专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US07410759B2 Compositions and methods for diagnosing and treating mood disorders 有权
标题翻译：用于诊断和治疗情绪障碍的组合和方法
公开(公告)号：US07410759B2
公开(公告)日：2008-08-12
申请号：US10701263
申请日：2003-11-03
申请人： Huda Akil , William E. Bunney, Jr. , Prabhakara V. Choudary , Simon J. Evans , Edward G. Jones , Jun Li , Juan F. Lopez , Robert C. Thompson , Richard Myers , Hiroaki Tomita , Marquis P. Vawter , Stanley Watson
发明人： Huda Akil , William E. Bunney, Jr. , Prabhakara V. Choudary , Simon J. Evans , Edward G. Jones , Jun Li , Juan F. Lopez , Robert C. Thompson , Richard Myers , Hiroaki Tomita , Marquis P. Vawter , Stanley Watson
IPC分类号： C12Q1/68 , G01N33/50
CPC分类号： C12Q1/6883 , C12Q2600/136 , C12Q2600/158
摘要： The present invention provides methods for diagnosing mental disorders such as mood disorders, including bipolar disorder I and II and major depression. The invention also provides methods of identifying modulators of such mental disorders as well as methods of using these modulators to treat patients suffering from such mental disorders.
摘要翻译：本发明提供诊断精神障碍如心理障碍的方法，包括双相情感障碍I和II以及重度抑郁症。本发明还提供鉴定这种精神障碍的调节剂的方法以及使用这些调节剂来治疗患有这种精神障碍的患者的方法。

2. 发明申请

US20110224144A1 COMPOSITIONS AND METHODS FOR DIAGNOSING AND TREATING MENTAL DISORDERS 审中-公开
标题翻译：用于诊断和治疗精神疾病的组合物和方法
公开(公告)号：US20110224144A1
公开(公告)日：2011-09-15
申请号：US12903039
申请日：2010-10-12
申请人： Huda Akil , Mary Atz , William E. Bunney, JR. , Prabhakara V. Choudary , Simon J. Evans , Edward G. Jones , Jun Li , Juan F. Lopez , Richard Myers , Robert C. Thompson , Hiroaki Tomita , Marquis P. Vawter , Stanley Watson
发明人： Huda Akil , Mary Atz , William E. Bunney, JR. , Prabhakara V. Choudary , Simon J. Evans , Edward G. Jones , Jun Li , Juan F. Lopez , Richard Myers , Robert C. Thompson , Hiroaki Tomita , Marquis P. Vawter , Stanley Watson
IPC分类号： A61K38/02 , G01N33/566 , A61K31/7088 , A61P25/00 , A61P25/18
CPC分类号： A61K31/519 , A61K31/7088 , G01N33/6893 , G01N2800/30 , G01N2800/302
摘要： The present invention provides methods for diagnosing mental disorders (e.g., psychotic disorders such as schizophrenia). The invention also provides methods of identifying modulators of such mental disorders as well as methods of using these modulators to treat patients suffering from such mental disorders.
摘要翻译：本发明提供了用于诊断精神障碍（例如精神病性精神障碍如精神分裂症）的方法。本发明还提供鉴定这种精神障碍的调节剂的方法以及使用这些调节剂来治疗患有这种精神障碍的患者的方法。

3. 发明申请

US20090117565A1 Compositions and methods for diagnosis and treating mood disorders 审中-公开
标题翻译：用于诊断和治疗情绪障碍的组合物和方法
公开(公告)号：US20090117565A1
公开(公告)日：2009-05-07
申请号：US12154419
申请日：2008-05-21
申请人： Huda Akil , William E. Bunney, JR. , Prabhakara V. Choudary , Simon J. Evans , Edward G. Jones , Jun Li , Juan F. Lopez , Robert C. Thompson , Richard Myers , Hiroaki Tomita , Marquis P. Vawter , Stanley Watson
发明人： Huda Akil , William E. Bunney, JR. , Prabhakara V. Choudary , Simon J. Evans , Edward G. Jones , Jun Li , Juan F. Lopez , Robert C. Thompson , Richard Myers , Hiroaki Tomita , Marquis P. Vawter , Stanley Watson
IPC分类号： C12Q1/68 , A61K38/02
CPC分类号： C12Q1/6883 , C12Q2600/136 , C12Q2600/158
摘要： The present invention provides methods for diagnosing mental disorders such as mood disorders, including bipolar disorder I and II and major depression; The invention also provides methods of identifying modulators of such mental disorders as well as methods of using these modulators to treat patients suffering from such mental disorders.
摘要翻译：本发明提供诊断精神障碍如心理障碍的方法，包括双相情感障碍I和II以及重度抑郁症; 本发明还提供鉴定这种精神障碍的调节剂的方法以及使用这些调节剂来治疗患有这种精神障碍的患者的方法。

4. 发明授权

US08415298B2 Administration of FGF2 for treamtent of anxiety 有权
标题翻译：管理FGF2治疗焦虑症
公开(公告)号：US08415298B2
公开(公告)日：2013-04-09
申请号：US11158530
申请日：2005-06-21
申请人： Huda Akil , William E. Bunney, Jr. , Prabhakara V. Choudary , Simon J. Evans , Edward G. Jones , Jun Li , Juan F. Lopez , David M. Lyons , Margherita Molnar , Richard M. Myers , Alan F. Schatzberg , Richard Stein , Robert C. Thompson , Hiroaki Tomita , Marquis P. Vawter , Stanley J. Watson
发明人： Huda Akil , William E. Bunney, Jr. , Prabhakara V. Choudary , Simon J. Evans , Edward G. Jones , Jun Li , Juan F. Lopez , David M. Lyons , Margherita Molnar , Richard M. Myers , Alan F. Schatzberg , Richard Stein , Robert C. Thompson , Hiroaki Tomita , Marquis P. Vawter , Stanley J. Watson
IPC分类号： A61K38/18
CPC分类号： C12Q1/6883 , A61K31/713 , A61K38/1825 , C07K16/22 , C12N15/1136 , C12N2310/14 , C12Q2600/136 , C12Q2600/156 , C12Q2600/158 , C12Q2600/172 , G01N33/6896 , G01N33/74 , G01N2333/726 , G01N2800/304
摘要： The present invention provides methods for diagnosing mental disorders. The invention also provides methods of identifying modulators of mental disorders as well as methods of using these modulators to treat patients suffering from mental disorders.
摘要翻译：本发明提供了诊断精神障碍的方法。本发明还提供识别精神障碍调节剂的方法以及使用这些调节剂治疗患有精神障碍的患者的方法。

5. 发明申请

US20110014610A1 COMPOSITIONS AND METHODS FOR DIAGNOSING AND TREATING NEUROPSYCHIATRIC DISORDERS 审中-公开
标题翻译：用于诊断和治疗神经缺血性疾病的组合物和方法
公开(公告)号：US20110014610A1
公开(公告)日：2011-01-20
申请号：US12701177
申请日：2010-02-05
申请人： Huda Akil , Mary Atz , William E. Bunney, JR. , William Byerley , Kathleen Casey , Prabhakara V. Choudary , Simon J. Evans , Edward G. Jones , Jun Li , Juan F. Lopez , Richard M. Myers , Brandi Rollins , Robert C. Thompson , Hiroaki Tomita , Marquis P. Vawter , Stanley J. Watson
发明人： Huda Akil , Mary Atz , William E. Bunney, JR. , William Byerley , Kathleen Casey , Prabhakara V. Choudary , Simon J. Evans , Edward G. Jones , Jun Li , Juan F. Lopez , Richard M. Myers , Brandi Rollins , Robert C. Thompson , Hiroaki Tomita , Marquis P. Vawter , Stanley J. Watson
IPC分类号： C12Q1/68 , G01N33/53
CPC分类号： G01N33/6893 , C12Q1/6883 , C12Q2600/136 , C12Q2600/156 , C12Q2600/158 , G01N33/573 , G01N33/6896 , G01N2500/00 , G01N2500/04 , G01N2800/28 , G01N2800/30 , G01N2800/302 , G01N2800/304
摘要： The present invention provides methods for diagnosing mental disorders (e.g., psychotic disorders such as schizophrenia and mood disorders such as major depression disorder and bipolar disorder). The invention also provides methods of identifying modulators of such mental disorders as well as methods of using these modulators to treat patients suffering from such mental disorders.
摘要翻译：本发明提供了用于诊断精神障碍（例如精神病性障碍如精神分裂症和情绪障碍如重性抑郁障碍和双相情感障碍）的方法。本发明还提供鉴定这种精神障碍的调节剂的方法以及使用这些调节剂来治疗患有这种精神障碍的患者的方法。

6. 发明授权

US07687235B2 Compositions and methods for diagnosing and treating neuropsychiatric disorders 有权
标题翻译：用于诊断和治疗神经精神障碍的组合物和方法
公开(公告)号：US07687235B2
公开(公告)日：2010-03-30
申请号：US11396050
申请日：2006-03-31
申请人： Huda Akil , Mary Atz , William E. Bunney, Jr. , William Byerley , Kathleen Casey , Prabhakara V. Choudary , Simon J. Evans , Edward G. Jones , Jun Li , Juan F. Lopez , Richard M. Myers , Brandi Rollins , Robert C. Thompson , Hiroaki Tomita , Marquis P. Vawter , Stanley J. Watson
发明人： Huda Akil , Mary Atz , William E. Bunney, Jr. , William Byerley , Kathleen Casey , Prabhakara V. Choudary , Simon J. Evans , Edward G. Jones , Jun Li , Juan F. Lopez , Richard M. Myers , Brandi Rollins , Robert C. Thompson , Hiroaki Tomita , Marquis P. Vawter , Stanley J. Watson
IPC分类号： C12Q1/68 , C12P19/34
CPC分类号： G01N33/6893 , C12Q1/6883 , C12Q2600/136 , C12Q2600/156 , C12Q2600/158 , G01N33/573 , G01N33/6896 , G01N2500/00 , G01N2500/04 , G01N2800/28 , G01N2800/30 , G01N2800/302 , G01N2800/304
摘要： The present invention provides methods for diagnosing mental disorders (e.g., psychotic disorders such as schizophrenia and mood disorders such as major depression disorder and bipolar disorder). The invention also provides methods of identifying modulators of such mental disorders as well as methods of using these modulators to treat patients suffering from such mental disorders.
摘要翻译：本发明提供了用于诊断精神障碍（例如精神病性障碍如精神分裂症和情绪障碍如重性抑郁障碍和双相情感障碍）的方法。本发明还提供鉴定这种精神障碍的调节剂的方法以及使用这些调节剂来治疗患有这种精神障碍的患者的方法。

7. 发明申请

US20090233842A1 FGF2-RELATED METHODS FOR DIAGNOSING AND TREATING DEPRESSION 审中-公开
标题翻译： FGF2相关方法诊断和治疗抑郁症
公开(公告)号：US20090233842A1
公开(公告)日：2009-09-17
申请号：US12093437
申请日：2006-11-13
申请人： Huda Akil , Stanley J. Watson , Simon J. Evans , Cortney Turner , Rene Bernard , Ilan Kerman , Robert C. Thompson , Margit Burmeister , Laura J. Scott , Fan Meng , Michael Boehnke , William E. Bunney, JR. , Marquis P. Vawter , Edward G. Jones , Prabhakara V. Choudary , Richard M. Myers , Alan F. Schatzberg , Jun Li , Devin Absher , Hiroaki Tomita
发明人： Huda Akil , Stanley J. Watson , Simon J. Evans , Cortney Turner , Rene Bernard , Ilan Kerman , Robert C. Thompson , Margit Burmeister , Laura J. Scott , Fan Meng , Michael Boehnke , William E. Bunney, JR. , Marquis P. Vawter , Edward G. Jones , Prabhakara V. Choudary , Richard M. Myers , Alan F. Schatzberg , Jun Li , Devin Absher , Hiroaki Tomita
IPC分类号： A61K38/00 , C12Q1/68
CPC分类号： C12Q1/6883 , A61K38/03 , A61K38/10 , A61K38/1774 , A61K38/1825 , C12Q2600/106 , C12Q2600/136 , C12Q2600/158 , G01N33/5023 , G01N2800/304
摘要： The present application relates to the treatment and diagnosis of mood disorders, including bipolar disorder, major depression disorder and schizophrenia. The invention provides novel diagnostic markers and assays, as well as research tools for the development and discovery of agents and compounds which are useful for treating patients who suffer from mental illness.
摘要翻译：本申请涉及心理障碍的治疗和诊断，包括双相情感障碍，重症抑郁障碍和精神分裂症。本发明提供了新的诊断标记和测定，以及用于开发和发现可用于治疗患有精神疾病的患者的药剂和化合物的研究工具。

8. 发明申请

US20080199866A1 SNP DETECTION AND OTHER METHODS FOR CHARACTERIZING AND TREATING BIPOLAR DISORDER AND OTHER AILMENTS 审中-公开
标题翻译：表征和处理双极性疾病及其他物质的SNP检测及其他方法
公开(公告)号：US20080199866A1
公开(公告)日：2008-08-21
申请号：US11868456
申请日：2007-10-05
申请人： Huda Akil , Stanley J. Watson , Simon J. Evans , Cortney Turner , Rene Bernard , Ilan Kerman , Robert Thompson , Margit Burmeister , Laura J. Scott , Fan Meng , Michael Boehnke , William Bunney , Marquis Vawter , Edward Jones , Prabhakara V. Choudary , Richard Myers , Alan Schatzberg , Jun Li , Devin Absher
发明人： Huda Akil , Stanley J. Watson , Simon J. Evans , Cortney Turner , Rene Bernard , Ilan Kerman , Robert Thompson , Margit Burmeister , Laura J. Scott , Fan Meng , Michael Boehnke , William Bunney , Marquis Vawter , Edward Jones , Prabhakara V. Choudary , Richard Myers , Alan Schatzberg , Jun Li , Devin Absher
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6883 , C12Q2600/136 , C12Q2600/156 , C12Q2600/158 , C12Q2600/172
摘要： The present application relates to the use of SNPs and differential exon expression to characterize, diagnose or treat bipolar disorder and other mental illnesses, such as major depressive disorder and schizophrenia.
摘要翻译：本申请涉及使用SNP和差异外显子表达来表征，诊断或治疗双相情感障碍和其他精神疾病，如重度抑郁障碍和精神分裂症。

9. 发明授权

US08667865B2 Hybrid transmission 有权
标题翻译：混合传输
公开(公告)号：US08667865B2
公开(公告)日：2014-03-11
申请号：US12815237
申请日：2010-06-14
申请人： David J. Hoyle , Simon J. Evans , Kevin W. Ford
发明人： David J. Hoyle , Simon J. Evans , Kevin W. Ford
IPC分类号： F16H37/06
CPC分类号： F16H47/02 , B60K17/35 , B60K23/08 , B60K23/0808 , F16H2003/0818 , Y10T74/19023 , Y10T74/19051
摘要： A transmission for a vehicle which includes a ground engaging structure driven from an output member of the transmission is disclosed, the transmission including a first input member connected to a prime mover, and a second input member drivable by the operation of a hydraulic drive motor, and the transmission being operable to transmit drive from the first input member to the output member in mechanical drive mode, and from the second input member to the output member in hydrostatic drive mode, the first input member providing a drive input from the prime mover to a mechanical drive train which includes a gear ratio selection apparatus, and for mechanical drive mode, the gear ratio selection apparatus providing for one of a plurality of alternative gear ratios to be selected by the engagement and/or disengagement of at least one power-shift clutch device, and the second input member being connected via a drive path to the output member, and there being a power-shift clutch device between the hydraulic drive motor and the second input member which is operative when the transmission is in hydrostatic drive mode, to transmit drive established by the operation of the hydraulic drive motor to the second input member.
摘要翻译：公开了一种用于车辆的变速器，其包括从变速器的输出构件驱动的地面接合结构，所述变速器包括连接到原动机的第一输入构件和通过液压驱动电动机的操作可驱动的第二输入构件，并且所述变速器可操作以在机械驱动模式下将驱动从所述第一输入构件传递到所述输出构件，并且在静液压驱动模式下将所述第二输入构件从所述第二输入构件传递到所述输出构件，所述第一输入构件提供从所述原动机到包括齿轮比选择装置和用于机械驱动模式的机械传动系，所述齿轮比选择装置提供通过至少一个动力换档的接合和/或分离来选择的多个替代齿轮比之一离合器装置，并且第二输入构件经由驱动路径连接到输出构件，并且存在动力换挡离合器装置使液压驱动马达和第二输入构件在变速器处于静液压驱动模式时可操作，以将通过液压驱动马达的操作建立的驱动传动到第二输入构件。

10. 发明申请

US20110030505A1 Hybrid Transmission 有权
标题翻译：混合传输
公开(公告)号：US20110030505A1
公开(公告)日：2011-02-10
申请号：US12815237
申请日：2010-06-14
申请人： David John Hoyle , Simon J. Evans , Kevin W. Ford
发明人： David John Hoyle , Simon J. Evans , Kevin W. Ford
IPC分类号： F16H37/06
CPC分类号： F16H47/02 , B60K17/35 , B60K23/08 , B60K23/0808 , F16H2003/0818 , Y10T74/19023 , Y10T74/19051
摘要： A transmission for a vehicle which includes a ground engaging structure driven from an output member of the transmission is disclosed, the transmission including a first input member connected to a prime mover, and a second input member drivable by the operation of a hydraulic drive motor, and the transmission being operable to transmit drive from the first input member to the output member in mechanical drive mode, and from the second input member to the output member in hydrostatic drive mode, the first input member providing a drive input from the prime mover to a mechanical drive train which includes a gear ratio selection apparatus, and for mechanical drive mode, the gear ratio selection apparatus providing for one of a plurality of alternative gear ratios to be selected by the engagement and/or disengagement of at least one power-shift clutch device, and the second input member being connected via a drive path to the output member, and there being a power-shift clutch device between the hydraulic drive motor and the second input member which is operative when the transmission is in hydrostatic drive mode, to transmit drive established by the operation of the hydraulic drive motor to the second input member.
摘要翻译：公开了一种用于车辆的变速器，其包括从变速器的输出构件驱动的地面接合结构，所述变速器包括连接到原动机的第一输入构件和通过液压驱动电动机的操作可驱动的第二输入构件，并且所述变速器可操作以在机械驱动模式下将驱动从所述第一输入构件传递到所述输出构件，并且在静液压驱动模式下从所述第二输入构件传递到所述输出构件，所述第一输入构件提供从所述原动机到包括齿轮比选择装置和用于机械驱动模式的机械传动系，所述齿轮比选择装置提供通过至少一个动力换档的接合和/或分离来选择的多个替代齿轮比之一离合器装置，并且第二输入构件经由驱动路径连接到输出构件，并且存在动力换挡离合器装置使液压驱动马达和第二输入构件在变速器处于静液压驱动模式时可操作，以将通过液压驱动马达的操作建立的驱动传动到第二输入构件。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式