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1. 发明申请

US20120238849A1 INFUSION SET COMPONENT WITH INTEGRATED ANALYTE SENSOR CONDUCTORS 审中-公开
标题翻译：具有集成分析仪传感器导线器的输注组件
公开(公告)号：US20120238849A1
公开(公告)日：2012-09-20
申请号：US13050814
申请日：2011-03-17
申请人： Kris R. HOLTZCLAW , Fan MENG
发明人： Kris R. HOLTZCLAW , Fan MENG
IPC分类号： A61B5/145 , A61M5/168
CPC分类号： A61M5/00 , A61B5/14532 , A61M5/14244 , A61M5/1723 , A61M39/08 , A61M2005/1726
摘要： An infusion set component for a fluid infusion device that delivers fluid to a patient is presented here. The component includes a tube formed from tubing material having an interior fluid canal defined therein to provide a fluid pathway from the fluid infusion device to the patient, a plurality of sensor conductors incorporated with the tubing material to facilitate sensing of an analyte of the patient by the fluid infusion device, and a combined infusion-sensor unit coupled to the tube and to the plurality of sensor conductors. The infusion-sensor unit accommodates delivery of fluid from the tube, and it also accommodates sensing of the analyte. The component may also include a connector assembly coupled to the tube and to the plurality of sensor conductors, to fluidly couple the fluid canal to a fluid reservoir of the fluid infusion device and to electrically couple the sensor conductors to an electronics module of the fluid infusion device.
摘要翻译：这里呈现用于将流体输送给患者的流体输注装置的输注组件。该组件包括由管材形成的管，其具有限定在其中的内部流体管道，以提供从流体输注装置到患者的流体路径，多个与管材料结合的传感器导体，以便于通过以下方式感测患者的分析物：流体输注装置，以及耦合到管和多个传感器导体的组合的输注 - 传感器单元。输液传感器单元容纳来自管的流体的输送，并且还适应对分析物的感测。该部件还可以包括连接器组件，其连接到管和多个传感器导体，以将流体管道流体地耦合到流体输注装置的流体容器，并将传感器导体电耦合到流体输注的电子模块设备。

2. 发明申请

US20150168217A1 METHODS AND APPARATUS FOR SPECTROMETRY 有权
标题翻译：方法和装置用于光谱测定
公开(公告)号：US20150168217A1
公开(公告)日：2015-06-18
申请号：US14325502
申请日：2014-07-08
申请人： Dirk Robert Englund , Edward H. Chen , Fan Meng , Tim Schroder , Noel Heng Loon Wang , Ren-Jye Shiue
发明人： Dirk Robert Englund , Edward H. Chen , Fan Meng , Tim Schroder , Noel Heng Loon Wang , Ren-Jye Shiue
IPC分类号： G01J3/45 , G01B9/02
CPC分类号： G01J3/0205 , G01J3/0218 , G01J3/0256 , G01J3/453 , G02B6/29344 , G02B6/4287
摘要： Multimode interference can be used to achieve ultra-high resolving powers (e.g., Q>105) with linewidths down to 10 pm at 1500 nm and a broad spectroscopy range (e.g., 400-2400 nm) within a monolithic, millimeter-scale device. For instance, multimode interference (MMI) in a tapered waveguide enables fine resolution and broadband spectroscopy in a compact, monolithic device. The operating range is limited by the transparency of the waveguide material and the sensitivity of the camera; thus, the technique can be easily extended into the ultraviolet and mid- and deep-infrared spectrum. Experiments show that a tapered fiber multimode interference spectrometer can operate across a range from 500 nm to 1600 nm (B=1.0576) without moving parts. The technique is suitable for on-chip tapered multimode waveguides, which could be fabricated in high volume by printing or optical lithography, for applications from biochemical sensing to the life and physical sciences.
摘要翻译：可以使用多模式干扰来实现超高分辨率功率（例如，Q> 105），线宽在1500nm处具有低至10μm，在单片毫米级装置内具有广泛的光谱范围（例如，400-2400nm）。例如，锥形波导中的多模干扰（MMI）可以在紧凑的单片设备中实现精细分辨率和宽带光谱。操作范围受波导材料的透明度和相机的灵敏度的限制; 因此，该技术可以容易地扩展到紫外线和中深红外光谱。实验表明，锥形光纤多模干涉光谱仪可以在500nm至1600nm（B = 1.0576）的范围内工作，无需移动部件。该技术适用于片上锥形多模波导，可通过印刷或光学光刻制造高容量，用于从生化传感到生命和物理科学的应用。

3. 发明授权

US08550997B2 Sensor and monitor system 有权
标题翻译：传感器和监视器系统
公开(公告)号：US08550997B2
公开(公告)日：2013-10-08
申请号：US12651213
申请日：2009-12-31
申请人： Cary Talbot , Kris R. Holtzclaw , Hans K. Wenstad , Gary Cohen , Brian T. Kannard , Keith E. DeBrunner , Joseph Makram Arsanious , Fan Meng , Andrew Michael Bryan , Ulrich H. Rankers
发明人： Cary Talbot , Kris R. Holtzclaw , Hans K. Wenstad , Gary Cohen , Brian T. Kannard , Keith E. DeBrunner , Joseph Makram Arsanious , Fan Meng , Andrew Michael Bryan , Ulrich H. Rankers
IPC分类号： A61B5/00 , A61B5/05
CPC分类号： A61B5/14532 , A61B5/14514 , A61B2560/0209 , A61B2560/0276 , A61B2560/0412 , A61B2560/0443 , A61B2560/0456
摘要： A monitor system is disclosed. The monitor system includes a sensor with a sensor port. The monitor system further includes a recorder with a recorder port within a recording housing. The recorder port interfaces with the sensor port to receive signals from the sensor port. A recorder clock is defined within the recorder housing, with a recorder processor to store signals from the sensor. The recorder includes a data port to interface with a dock receiver. The monitor system includes a dock remotely located from the sensor and the recorder. The dock receiver couples the recorder to the dock. The monitor system further includes a data processor to analyze the sensor signals from the recorder. The data processor includes memory and a clock. Further included with the data processor are program instructions to assign the time and date of the sensor signals.
摘要翻译：公开了一种监视器系统。监视器系统包括一个带传感器端口的传感器。监视器系统还包括具有在记录外壳内的记录器端口的记录器。记录器端口与传感器端口连接，以从传感器端口接收信号。记录器时钟被定义在记录器外壳内，记录器处理器存储来自传感器的信号。记录器包括与坞站接收器接口的数据端口。监视器系统包括远离传感器和记录器的基座。码头接收器将录音机连接到码头。监视器系统还包括数据处理器，用于分析来自记录器的传感器信号。数据处理器包括存储器和时钟。数据处理器还包括用于分配传感器信号的时间和日期的程序指令。

4. 发明申请

US20110104674A1 SNP DETECTION AND OTHER METHODS FOR CHARACTERIZING AND TREATING BIPOLAR DISORDER AND OTHER AILMENTS 审中-公开
标题翻译：表征和处理双极性疾病及其他物质的SNP检测及其他方法
公开(公告)号：US20110104674A1
公开(公告)日：2011-05-05
申请号：US12764023
申请日：2010-04-20
申请人： HUDA AKIL , STANLEY J. WATSON , SIMON J. EVANS , CORTNEY TURNER , RENE BERNARD , ILAN KERMAN , ROBERT THOMPSON , MARGIT BURMEISTER , LAURA J. SCOTT , FAN MENG , MICHAEL BOEHNKE , WILLIAM BUNNEY , MARQUIS VAWTER , EDWARD JONES , PRABHAKARA V. CHOUDARY , RICHARD MYERS , ALAN SCHATZBERG , JUN LI , DEVIN ABSHER
发明人： HUDA AKIL , STANLEY J. WATSON , SIMON J. EVANS , CORTNEY TURNER , RENE BERNARD , ILAN KERMAN , ROBERT THOMPSON , MARGIT BURMEISTER , LAURA J. SCOTT , FAN MENG , MICHAEL BOEHNKE , WILLIAM BUNNEY , MARQUIS VAWTER , EDWARD JONES , PRABHAKARA V. CHOUDARY , RICHARD MYERS , ALAN SCHATZBERG , JUN LI , DEVIN ABSHER
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6883 , C12Q2600/136 , C12Q2600/156 , C12Q2600/158 , C12Q2600/172
摘要： The present application relates to the use of SNPs and differential exon expression to characterize, diagnose or treat bipolar disorder and other mental illnesses, such as major depressive disorder and schizophrenia.
摘要翻译：本申请涉及使用SNP和差异外显子表达来表征，诊断或治疗双相情感障碍和其他精神疾病，如重度抑郁障碍和精神分裂症。

5. 发明申请

US20090019557A1 FGF2-RELATED METHODS FOR DIAGNOSING AND TREATING DEPRESSION 审中-公开
公开(公告)号：US20090019557A1
公开(公告)日：2009-01-15
申请号：US11559398
申请日：2006-11-13
申请人： Huda Akil , Stanley Watson , Simon Evans , Cortney Turner , Rene Bernard , Ilan Kerman , Robert C. Thompson , Margit Burmeister , Laura J. Scott , Fan Meng , Michael Boehnke , William Bunney , Marquis Vawter , Edward Jones , Prabhakara Choudary , Richard Myers , Alan Schatzberg , Jun Li , Devin Absher , Hiroaki Tomita
发明人： Huda Akil , Stanley Watson , Simon Evans , Cortney Turner , Rene Bernard , Ilan Kerman , Robert C. Thompson , Margit Burmeister , Laura J. Scott , Fan Meng , Michael Boehnke , William Bunney , Marquis Vawter , Edward Jones , Prabhakara Choudary , Richard Myers , Alan Schatzberg , Jun Li , Devin Absher , Hiroaki Tomita
IPC分类号： A01K67/00 , C12Q1/68 , C12Q1/02 , G01N33/68 , A61K38/17
CPC分类号： C12Q1/6883 , A61K38/03 , A61K38/10 , A61K38/1774 , A61K38/1825 , C12Q2600/106 , C12Q2600/136 , C12Q2600/158 , G01N33/5023 , G01N2800/304
摘要： The present application relates to the treatment and diagnosis of mood disorders, including bipolar disorder, major depression disorder and schizophrenia. The invention provides novel diagnostic markers and assays, as well as research tools for the development and discovery of agents and compounds which are useful for treating patients who suffer from mental illness.

6. 发明申请

US20110160553A1 Sensor and monitor system 有权
标题翻译：传感器和监视器系统
公开(公告)号：US20110160553A1
公开(公告)日：2011-06-30
申请号：US12651213
申请日：2009-12-31
申请人： Cary Talbot , Kris R. Holtzclaw , Hans K. Wanstad , Gary Cohen , Brian T. Kannard , Keith E. DeBrunner , Joseph Makram Arsanious , Fan Meng , Andrew Michael Bryan , Ulrich H. Rankers
发明人： Cary Talbot , Kris R. Holtzclaw , Hans K. Wanstad , Gary Cohen , Brian T. Kannard , Keith E. DeBrunner , Joseph Makram Arsanious , Fan Meng , Andrew Michael Bryan , Ulrich H. Rankers
IPC分类号： A61B5/145
CPC分类号： A61B5/14532 , A61B5/14514 , A61B2560/0209 , A61B2560/0276 , A61B2560/0412 , A61B2560/0443 , A61B2560/0456
摘要： A monitor system to monitor a characteristic of a user is disclosed. The monitor system includes a sensor to produce a signal indicative of a glucose characteristic measured in the user, the sensor further having a sensor port. The monitor system further includes a recorder within a recording housing, the recorder hosing also encompassing a batter. The recorder further includes a recorder port that interfaces with the sensor port in order to receive the produced signals from the sensor port. A recorder clock that assigns a time to the signals from the sensor is also defined within the recorder housing, as is a recorder processor that includes a recorder memory that is coupled to the recorder port to store the produced signals from the sensor. The recorder further includes a data port defined to interface with a dock receiver. A dock that is remotely located from the sensor and the recorder is also included with the monitor system. The dock includes the dock receiver that physically couples the recorder to the dock via the data port and a dock processor that is coupled to the dock receiver. The monitor system further includes a data processor defined to analyze the signals from the sensor that were stored in the recorder. The data processor includes: a data processor memory to store data from the recorder and a data processor clock. Further included with the data processor is a program to assign the time and date of the signals from the sensor by comparing the time and date on the data processor clock with the time assigned to the signals from the sensor by the recorder clock.
摘要翻译：公开了一种用于监视用户特性的监视器系统。监视器系统包括传感器，用于产生指示在用户中测量的葡萄糖特性的信号，该传感器还具有传感器端口。监视器系统还包括在记录外壳内的记录器，记录器还包括面糊。记录器还包括与传感器端口接口以便从传感器端口接收所产生的信号的记录器端口。在记录器外壳内也定义了一个将时间分配给传感器的信号的记录器时钟，记录器处理器还包括与记录器端口相连的记录器存储器，以存储来自传感器的信号。记录器还包括被定义为与码头接收器接口的数据端口。远程位于传感器和记录仪的底座也包含在监视器系统中。码头包括通过数据端口将记录器物理耦合到坞站的坞站接收器和耦合到坞站接收器的坞站处理器。监视器系统还包括定义为分析存储在记录器中的来自传感器的信号的数据处理器。数据处理器包括：数据处理器存储器，用于存储来自记录器的数据和数据处理器时钟。数据处理器还包括一个程序，通过将数据处理器时钟上的时间和日期与分配给传感器的信号的时间与记录器时钟进行比较，来分配来自传感器的信号的时间和日期。

7. 发明申请

US20090233842A1 FGF2-RELATED METHODS FOR DIAGNOSING AND TREATING DEPRESSION 审中-公开
标题翻译： FGF2相关方法诊断和治疗抑郁症
公开(公告)号：US20090233842A1
公开(公告)日：2009-09-17
申请号：US12093437
申请日：2006-11-13
申请人： Huda Akil , Stanley J. Watson , Simon J. Evans , Cortney Turner , Rene Bernard , Ilan Kerman , Robert C. Thompson , Margit Burmeister , Laura J. Scott , Fan Meng , Michael Boehnke , William E. Bunney, JR. , Marquis P. Vawter , Edward G. Jones , Prabhakara V. Choudary , Richard M. Myers , Alan F. Schatzberg , Jun Li , Devin Absher , Hiroaki Tomita
发明人： Huda Akil , Stanley J. Watson , Simon J. Evans , Cortney Turner , Rene Bernard , Ilan Kerman , Robert C. Thompson , Margit Burmeister , Laura J. Scott , Fan Meng , Michael Boehnke , William E. Bunney, JR. , Marquis P. Vawter , Edward G. Jones , Prabhakara V. Choudary , Richard M. Myers , Alan F. Schatzberg , Jun Li , Devin Absher , Hiroaki Tomita
IPC分类号： A61K38/00 , C12Q1/68
CPC分类号： C12Q1/6883 , A61K38/03 , A61K38/10 , A61K38/1774 , A61K38/1825 , C12Q2600/106 , C12Q2600/136 , C12Q2600/158 , G01N33/5023 , G01N2800/304
摘要： The present application relates to the treatment and diagnosis of mood disorders, including bipolar disorder, major depression disorder and schizophrenia. The invention provides novel diagnostic markers and assays, as well as research tools for the development and discovery of agents and compounds which are useful for treating patients who suffer from mental illness.
摘要翻译：本申请涉及心理障碍的治疗和诊断，包括双相情感障碍，重症抑郁障碍和精神分裂症。本发明提供了新的诊断标记和测定，以及用于开发和发现可用于治疗患有精神疾病的患者的药剂和化合物的研究工具。

8. 发明申请

US20080199866A1 SNP DETECTION AND OTHER METHODS FOR CHARACTERIZING AND TREATING BIPOLAR DISORDER AND OTHER AILMENTS 审中-公开
标题翻译：表征和处理双极性疾病及其他物质的SNP检测及其他方法
公开(公告)号：US20080199866A1
公开(公告)日：2008-08-21
申请号：US11868456
申请日：2007-10-05
申请人： Huda Akil , Stanley J. Watson , Simon J. Evans , Cortney Turner , Rene Bernard , Ilan Kerman , Robert Thompson , Margit Burmeister , Laura J. Scott , Fan Meng , Michael Boehnke , William Bunney , Marquis Vawter , Edward Jones , Prabhakara V. Choudary , Richard Myers , Alan Schatzberg , Jun Li , Devin Absher
发明人： Huda Akil , Stanley J. Watson , Simon J. Evans , Cortney Turner , Rene Bernard , Ilan Kerman , Robert Thompson , Margit Burmeister , Laura J. Scott , Fan Meng , Michael Boehnke , William Bunney , Marquis Vawter , Edward Jones , Prabhakara V. Choudary , Richard Myers , Alan Schatzberg , Jun Li , Devin Absher
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6883 , C12Q2600/136 , C12Q2600/156 , C12Q2600/158 , C12Q2600/172
摘要： The present application relates to the use of SNPs and differential exon expression to characterize, diagnose or treat bipolar disorder and other mental illnesses, such as major depressive disorder and schizophrenia.
摘要翻译：本申请涉及使用SNP和差异外显子表达来表征，诊断或治疗双相情感障碍和其他精神疾病，如重度抑郁障碍和精神分裂症。

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