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    • 9. 发明授权
    • Granule containing physiologically-active substance, method for
preparing same and use thereof
    • 含有生理活性物质的颗粒,其制备方法及其用途
    • US4713245A
    • 1987-12-15
    • US737407
    • 1985-05-24
    • Shinji AndoMasami OhtaguroTakayoshi MasudaYoshimoto Watanabe
    • Shinji AndoMasami OhtaguroTakayoshi MasudaYoshimoto Watanabe
    • A23K1/00A61K9/16A61K9/42A61K9/50
    • A61K9/501A23K40/00A23K40/35A61K9/1611A61K9/1617A61K9/1635A61K9/1652Y10S426/807
    • Disclosed herein is a granule containing physiologically-active substance which comprises at least(A): a physiologically-active substance;(B): a substance which is stable under neutral condition but disintegrates or dissolves at a pH of 3 or less; and(C): at least one substance selected from the group consisting of straight-chain or branched, saturated or unsaturated monocarboxylic acids having at least 14 carbon atoms and salts thereof, animal fats having a melting point of 40.degree. C. or higher, vegetable fats having a melting point of 40.degree. C. or higher and waxes having a melting point of 40.degree. C. or higher, and which granule further has a protective film comprising at least said substances (B) and (C) on the surface thereof. The protective film has a thickness of preferably at most 20% of the granular diameter and is preferably at least composed of at least 10% by weight of the substance (B) and at most 90% by weight of the substance (C). Granules having this specific protective film on the surface thereof have the use as a feed additive composition. A method for preparing said granules is also disclosed.
    • 本文公开了含有生理活性物质的颗粒,其至少包含(A):生理活性物质; (B):在中性条件下稳定但在pH3以下分解或溶解的物质; 和(C):选自具有至少14个碳原子的直链或支链,饱和或不饱和一元羧酸及其盐的至少一种物质,熔点为40℃或更高的动物脂肪, 熔点为40℃以上的植物脂肪和熔点为40℃以上的蜡,该颗粒还具有在表面上至少含有上述物质(B)和(C)的保护膜 其中。 保护膜的厚度优选为粒径的至多20%,优选至少为物质(B)的至少10重量%和物质(C)的至多90重量%。 在其表面具有该特定保护膜的颗粒具有作为饲料添加剂组合物的用途。 还公开了制备所述颗粒的方法。