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1. 发明授权

US07284405B2 Pressure controlled fluid pressure extrusion method 失效
标题翻译：压力流体压力挤压法
公开(公告)号：US07284405B2
公开(公告)日：2007-10-23
申请号：US10431114
申请日：2003-05-06
申请人： Hisanobu Kanamaru , Kazuto Kobayashi
发明人： Hisanobu Kanamaru , Kazuto Kobayashi
IPC分类号： B21C23/00
CPC分类号： B21C23/007 , B21C23/10 , B21J5/04 , B21J5/12 , B21K1/066 , B21K1/12 , B21K1/30
摘要： The lower part of a material to be molded forms a lower, seal with a die. A punch applying a molding force to the material forms an upper seal with the perimeter of the die. The space between the upper and lower, seals forms a pressure chamber that is filled with a fluid. As the punch descends into the die, the fluid is pressurized. The lower seal is a complete seal to prevent leakage of fluid into the die. The upper seal is given a clearance with the die that permits controlled leakage of fluid therepast at a rate that limits the maximum pressure in the pressure chamber while permitting the development of an adequate pressure on the material being molded.
摘要翻译：待模制材料的下部与模具形成较低的密封。将模塑力施加到材料上的冲头与模具的周边形成上密封。上部和下部之间的密封件形成充满流体的压力室。当冲头下降到模具中时，流体被加压。下密封是完整的密封，以防止流体泄漏到模具中。上密封件与模具给予间隙，其允许以限制压力室中的最大压力的速率控制流体的泄漏，同时允许在正在模制的材料上产生足够的压力。

2. 发明授权

US06406374B1 Outer ring of a constant velocity universal joint and manufacturing method for the same 失效
标题翻译：等速万向节外环及其制造方法
公开(公告)号：US06406374B1
公开(公告)日：2002-06-18
申请号：US09578754
申请日：2000-05-25
申请人： Hisanobu Kanamaru , Nobuyuki Ishinaga , Kazuto Kobayashi , Akira Matsumura
发明人： Hisanobu Kanamaru , Nobuyuki Ishinaga , Kazuto Kobayashi , Akira Matsumura
IPC分类号： F16D316
CPC分类号： B21D26/047 , B21K1/762 , B21K1/765 , Y10S464/905 , Y10S464/906 , Y10T403/7026
摘要： A groove is cut into an end surface of a shaft component to deform the shaft component into irregularities provided on a tubular component, thereby coupling the shaft component with the tubular component to form an outer ring for a constant velocity joint. This type of joint provides an outer ring having a strong coupling force and high coupling precision. The irregularities are preferably in the form of a spline cut in a portion of an inner perimeter surface of the tubular component, at a location where coupling of the tubular component with the shaft component is desired. The spline optionally includes a notch which provided additional coupling strength, especially in the shaft direction. The tubular component is shaped by pressing the inner surface of the tubular component into a mandrel having an outer surface shape of the desired inner surface shape of the tubular component. Hydraulic pressure is used to supply the force to press the material onto the mandrel to form the tubular component. This shaping method results in a molded material with high precision without requiring bond treatment.
摘要翻译：将槽切割成轴部件的端面，以将轴部件变形成设置在管状部件上的凹凸，从而将轴部件与管状部件联接以形成用于等速万向节的外圈。这种类型的接头提供了具有很强耦合力和高耦合精度的外圈。优选地，在管状部件的内周表面的一部分中，在期望管状部件与轴部件的联接的位置处，不规则部分形式为花键切割。花键可选地包括提供额外的联接强度的切口，特别是在轴向上。管状部件通过将管状部件的内表面压入具有管状部件的所需内表面形状的外表面形状的心轴中而成形。使用液压来提供力以将材料压在心轴上以形成管状部件。这种成形方法产生了高精度的模制材料，而不需要粘合处理。

3. 发明授权

US06250121B1 Method for molding metal using high fluid pressure 有权
标题翻译：使用高流体压力成型金属的方法
公开(公告)号：US06250121B1
公开(公告)日：2001-06-26
申请号：US09545082
申请日：2000-04-07
申请人： Kazuto Kobayashi , Hisanobu Kanamaru , Akira Matsumura
发明人： Kazuto Kobayashi , Hisanobu Kanamaru , Akira Matsumura
IPC分类号： B21D2602
CPC分类号： B21J5/04 , B21J5/02
摘要： A molding method uses a fluid-pressure generating unit form generating high fluid pressures that allows high-precision molding of complex shapes. The high fluid pressure is generated with a piston disposed in communication with a molding cavity. The high fluid pressure is imposed on a raw material workpiece to push the workpiece into a cavity causing the workpiece to conform to the shape of the cavity thereby producing an article of desired shape.
摘要翻译：模制方法使用产生高流体压力的流体压力产生单元，其允许复杂形状的高精度模塑。高流体压力是通过设置成与模腔连通的活塞产生的。高的流体压力施加在原材料工件上以将工件推入空腔中，使得工件符合空腔的形状，从而产生所需形状的制品。

4. 发明授权

US09006411B2 Neuron-specific retrograde transport vector 有权
标题翻译：神经元特异性逆行运输载体
公开(公告)号：US09006411B2
公开(公告)日：2015-04-14
申请号：US13988973
申请日：2011-11-25
申请人： Kazuto Kobayashi
发明人： Kazuto Kobayashi
IPC分类号： C07K14/005 , A01N63/00 , A01N65/00 , C12N15/86 , A61K48/00
CPC分类号： C12N15/86 , A61K48/0058 , C07K14/005 , C07K2319/00 , C07K2319/03 , C12N2740/16045 , C12N2740/16071 , C12N2760/20122 , C12N2760/20222 , C12N2810/6081
摘要： The present invention provides a lentiviral vector system having a higher titer, while sustaining an excellent retrograde transport ability, particularly, in the brain.The present invention also provides a kit for preparing a retrograde transport viral vector comprising: (1) a packaging plasmid containing the gag gene and the pol gene of HIV-1; (2) a packaging plasmid containing an accessory gene of HIV-1; (3) a transfer plasmid containing an target gene (a transgene); and (4) an envelope plasmid containing, as an envelope gene, a gene encoding a fused polypeptide comprising a fused extracellular domain consisting of the N-terminal region of an extracellular domain of rabies virus glycoprotein (RV-G) and the C-terminal region of an extracellular domain of vesicular stomatitis virus glycoprotein (VSV-G), a transmembrane domain of RV-G or VSV-G, and an intracellular domain of VSV-G, and the like.
摘要翻译：本发明提供了具有较高滴度的慢病毒载体系统，同时维持优异的逆行转运能力，特别是在脑中。本发明还提供了用于制备逆行转运病毒载体的试剂盒，其包含：（1）含有HIV-1的gag基因和pol基因的包装质粒; （2）含有HIV-1辅助基因的包装质粒; （3）含有靶基因（转基因）的转移质粒; （4）包含作为包膜基因的包含编码融合多肽的基因的包膜质粒，所述融合多肽包含由狂犬病病毒糖蛋白（RV-G）的细胞外结构域的N末端区域构成的融合细胞外结构域和C-末端水泡性口炎病毒糖蛋白（VSV-G）的细胞外结构域，RV-G或VSV-G的跨膜结构域和VSV-G的细胞内结构域等。

5. 发明授权

US08806880B2 Expansion valve 有权
标题翻译：膨胀阀
公开(公告)号：US08806880B2
公开(公告)日：2014-08-19
申请号：US12680991
申请日：2008-09-18
申请人： Kazuto Kobayashi , Takashi Mogi , Eiji Fukuda
发明人： Kazuto Kobayashi , Takashi Mogi , Eiji Fukuda
IPC分类号： F25B41/06
CPC分类号： F25B41/062 , F16K27/02 , F25B2341/0683 , F25B2500/01
摘要： An expansion valve for reducing the quantity of material required for the valve body by contriving the arrangement of bolt fitting grooves. In the expansion valve (20), displacement of a valve member driver (36) provided in the valve body (21) is transmitted to a valve member by a valve member drive rod (36f) and the valve opening is altered to control the flow rate of the refrigerant. The valve body (21) consists of a body upper portion (40) and a body lower portion (41) narrower than the body upper portion (40), and bolt fitting grooves (43, 43) opening in the flank of the valve body (21), preferably opening obliquely downward, are formed at the boundary (42) of the body upper portion (40) and the body lower portion (41). With such a layout, the material required at the boundary (42) can be reduced furthermore and the quantity of material required for the valve body (21) can be reduced furthermore, as a result. Since the opening width (minimum spatial dimension) w is smaller than the diameter of bolt, a seating surface is assured sufficiently around the bolt fitting groove (43) and the bolt does not drop off from the bolt fitting groove (43).
摘要翻译：一种膨胀阀，用于通过设计螺栓安装槽来减少阀体所需的材料的数量。在膨胀阀（20）中，设置在阀体（21）中的阀构件驱动器（36）的位移通过阀构件驱动杆（36f）传递到阀构件，并且改变阀开度以控制流量制冷剂的比例。阀体（21）由主体上部（40）和比主体上部（40）窄的主体下部（41）构成，在阀体的侧面开口的螺栓嵌合槽（43,43）（21），优选地向下倾斜地开口，形成在主体上部（40）和主体下部（41）的边界（42）处。通过这样的布局，可以进一步减少在边界（42）处所需的材料，并且可以进一步降低阀体（21）所需的材料量。由于开口宽度（最小空间尺寸）w小于螺栓的直径，因此在螺栓配合槽（43）周围充分确保就座面，并且螺栓不会从螺栓配合槽（43）脱落。

6. 发明授权

US08635775B2 Process for manufacturing a bearing ring member as a constituent of a rolling bearing unit for wheel support 有权
标题翻译：用于制造用于车轮支撑的滚动轴承单元的构件的轴承环构件的制造方法
公开(公告)号：US08635775B2
公开(公告)日：2014-01-28
申请号：US12096725
申请日：2006-12-05
申请人： Kazuto Kobayashi , Yuu Yasuda , Kiyoshi Ootsuka
发明人： Kazuto Kobayashi , Yuu Yasuda , Kiyoshi Ootsuka
IPC分类号： B21K1/40
CPC分类号： B21K1/40 , B21J5/02 , B21K23/04 , F16C19/186 , F16C33/64 , F16C2326/02 , Y10T29/49533 , Y10T29/49636 , Y10T29/49679 , Y10T29/49689
摘要： This invention provided a manufacturing method to process a small-diameter step section 18 on an inside end section of a hub body 13a that comprises an outward facing flange 15 and a positioning cylinder 16 stably and with high precision. In this invention, an intermediate material 40 is pressed between a lower punch 36 and an upper punch 46 with an outer peripheral surface of the intermediate material 40 being held by a lower die 37 and an upper die 43, and then a part of the intermediate material 40 is pressed into the lower punch 36 such that the small-diameter step section 18 is formed by cold plastic working.
摘要翻译：本发明提供了一种在毂体13a的内端部处处理小直径台阶部18的制造方法，其特征在于，其具有稳定且高精度的向外凸缘15和定位筒16。在本发明中，中间材料40被压在下冲头36和上冲头46之间，中间材料40的外周面由下模37和上模43保持，然后是中间材料的一部分材料40被压入下冲头36，使得小直径台阶部分18通过冷塑性加工形成。

7. 发明授权

US08424208B2 Manufacturing method for bearing outer ring 有权
标题翻译：轴承外圈的制造方法
公开(公告)号：US08424208B2
公开(公告)日：2013-04-23
申请号：US12522311
申请日：2008-01-16
申请人： Kazuto Kobayashi , Hiroshi Koyama
发明人： Kazuto Kobayashi , Hiroshi Koyama
IPC分类号： B21D53/10 , B21J5/08 , F16C33/58
CPC分类号： B23P15/003 , B21H1/12 , B21J1/00 , B21J1/04 , B21J5/02 , B21J5/10 , B21K1/04 , B21K21/02 , F16C19/184 , F16C33/62 , F16C33/64 , Y10T29/49636 , Y10T29/49643 , Y10T29/49689
摘要： Provided is a manufacturing method of an outer ring (3) of a back-to-back arrangement double-row angular ball bearing from a raw material (10) comprising a upsetting (A to B), a backward extrusion process (C to D), a punching (D to E), a rolling (E to F) and a finishing, wherein an outer diameter of a first intermediate material (11a) produced by the upsetting is equal to or smaller than an inside diameter of an inner periphery large diameter portion (18) of the inner circumference of a die (13) used in the backward extrusion process and larger than an inside diameter of an inner periphery small portion (19) of the die (13), and in a condition with the first intermediate material (11a) sitting on the inner periphery inclined portion (20) of the die (13), the intermediate material (11a) is pushed toward a base of the die (13) by a punch (14), to thereby the middle metal material (29) with the highest cleanliness of the raw material (10) is exposed to the two outer ring raceways (2) of the outer ring (3).
摘要翻译：本发明提供从包括镦粗（A〜B），向后挤压工序（C〜D）的原料（10）的背靠背排列双列角球轴承的外圈（3）的制造方法），冲压（D〜E），轧制（E〜F）和精加工，其中通过镦锻制造的第一中间材料（11a）的外径等于或小于内周的内径在向后挤压过程中使用的模具（13）的内周的大直径部分（18）大于模具（13）的内周小部分（19）的内径，并且在第一中间材料（11a）位于模具（13）的内周倾斜部分（20）上，中间材料（11a）通过冲头（14）被推向模具（13）的基部，由此原料（10）清洁度最高的中间金属材料（29）暴露于t的两个外圈滚道（2）他外圈（3）。

8. 发明申请

US20130008275A1 Method for Manufacturing Nut for Ball Screw and Ball Screw 有权
标题翻译：滚珠丝杠和滚珠丝杠螺母的制造方法
公开(公告)号：US20130008275A1
公开(公告)日：2013-01-10
申请号：US13581258
申请日：2011-03-31
申请人： Atsushi Watanabe , Toru Harada , Shouji Yokoyama , Kiyoshi Ootsuka , Koji Hashimoto , Kazuto Kobayashi , Toshio Nakamura , Shinobu Mogi , Shingo Saitou , Tomofumi Yamashita
发明人： Atsushi Watanabe , Toru Harada , Shouji Yokoyama , Kiyoshi Ootsuka , Koji Hashimoto , Kazuto Kobayashi , Toshio Nakamura , Shinobu Mogi , Shingo Saitou , Tomofumi Yamashita
IPC分类号： B21K1/70 , F16H25/22
CPC分类号： B21K1/70 , B21J5/12 , B21J13/025 , B21K1/04 , B21K21/12 , B21K21/16 , B21K23/00 , F16H25/2223 , F16H2025/2481 , Y10T74/19749 , Y10T74/19767 , Y10T74/19772
摘要： A method forms a concave constituting a ball return passage directly on an inner circumferential surface of a nut blank by plastic working without damaging a die. Letter S shaped concaves are formed on an inner circumferential surface of a nut blank, by pressing by use of a die having a blank holder, a cam driver, cam sliders, and a cylindrical member. The cam driver has inclined surfaces having the same angle of inclination as the cam sliders. The cam sliders have letter S shaped convexes corresponding to the letter S shaped concaves, and are held by through holes, respectively. When the cam driver is pressed from the top thereof, the cam sliders move outwardly in the radial direction, respectively, and the letter S shaped convexes push the inner circumferential surface of the nut blank for plastic deformation.
摘要翻译：一种方法通过塑料加工在螺母坯件的内周面上直接形成一个构成球返回通道的凹槽，而不会损坏模具。通过使用具有坯料保持器，凸轮驱动器，凸轮滑块和圆柱形构件的模具进行压制，在螺母坯料的内周面上形成字母S形凹部。凸轮驱动器具有与凸轮滑块具有相同倾斜角度的倾斜表面。凸轮滑块具有对应于字母S形凹部的字母S形凸起，并且分别由通孔保持。当凸轮驱动器从其顶部按压时，凸轮滑块分别沿径向向外移动，字母S形凸起推动螺母坯件的内圆周表面以塑性变形。

9. 发明申请

US20120295964A1 RETROGRADE TRANSPORT VIRAL VECTOR SYSTEM HAVING ENVELOPE COMPRISING FUSED GLYCOPROTEIN 有权
标题翻译：带有融合的糖蛋白的包装的退货运输病毒载体系统
公开(公告)号：US20120295964A1
公开(公告)日：2012-11-22
申请号：US13511873
申请日：2010-11-11
申请人： Kazuto Kobayashi
发明人： Kazuto Kobayashi
IPC分类号： C12N15/86 , C12N15/87 , A61P25/16 , C07K14/145 , C12N15/47 , C12N5/0783 , A61K48/00
CPC分类号： A61K48/0075 , C07K14/005 , C12N15/86 , C12N2740/16045 , C12N2740/16052 , C12N2760/20122 , C12N2760/20222 , C12N2810/6081
摘要： Provided is a lentiviral vector system which sustains a high-frequency retrograde transportation ability in animal brain and has a higher titer. A kit for preparing a retrograde transport viral vector, which comprises: (1) a packaging plasmid containing the gag gene and pol gene of HIV-1; (2) a packaging plasmid containing an accessory gene of HIV-1; (3) a transfer plasmid containing a target gene; and (4) an envelope plasmid containing, as an envelope gene, a gene encoding a fused polypeptide comprising the extracellular domain of rabies virus glycoprotein (RV-G), the transmembrane domain of rabies virus glycoprotein (RV-G) or vesicular stomatitis virus glycoprotein (VSV-G) and the intracellular domain of vesicular stomatitis virus glycoprotein (VSV-G).
摘要翻译：提供了一种在动物脑中维持高频逆行运输能力并具有较高滴度的慢病毒载体系统。一种用于制备逆行转运病毒载体的试剂盒，其包括：（1）含有HIV-1的gag基因和pol基因的包装质粒; （2）含有HIV-1辅助基因的包装质粒; （3）含有靶基因的转移质粒; （4）包含作为包膜基因的包含狂犬病病毒糖蛋白（RV-G）细胞外结构域，狂犬病病毒糖蛋白（RV-G）或水泡性口炎病毒的跨膜结构域的融合多肽的基因的包膜质粒糖蛋白（VSV-G）和水泡性口炎病毒糖蛋白（VSV-G）的细胞内结构域。

10. 发明授权

US08149819B2 ENUM system, ENUM client apparatus and method for communicating using ENUM client apparatus 失效
标题翻译： ENUM系统，ENUM客户端设备和使用ENUM客户端设备进行通信的方法
公开(公告)号：US08149819B2
公开(公告)日：2012-04-03
申请号：US11166236
申请日：2005-06-27
申请人： Kazuto Kobayashi , Akira Miyajima
发明人： Kazuto Kobayashi , Akira Miyajima
IPC分类号： G06F15/16 , H04L12/66
CPC分类号： H04M7/006
摘要： An ENUM system includes a Web server and an ENUM server. The Web server stores first NAPTR records corresponding to an ENUM client and another ENUM client on an IP network. The ENUM server stores second NAPTR records in which first URIs are associated with predetermined information for being linked to the Web server. In the ENUM system, the ENUM client transmits, to the ENUM server, a query for the second NAPTR record of the another ENUM client. The ENUM client then transmits, to the Web server, a request for access to the first URI included in the received second NAPTR record, and obtains the first NAPTR record corresponding to the another ENUM client.
摘要翻译： ENUM系统包括Web服务器和ENUM服务器。 Web服务器在IP网络上存储对应于ENUM客户端和另一个ENUM客户端的第一个NAPTR记录。 ENUM服务器存储第二个NAPTR记录，其中第一个URI与预定的信息相关联，以链接到Web服务器。在ENUM系统中，ENUM客户端向ENUM服务器发送另一个ENUM客户端的第二个NAPTR记录的查询。然后，ENUM客户端向Web服务器发送访问包括在接收的第二NAPTR记录中的第一URI的请求，并且获得与另一ENUM客户端对应的第一NAPTR记录。

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