专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20090020695A1 MASS SPECTROMETER 有权
标题翻译：质谱仪
公开(公告)号：US20090020695A1
公开(公告)日：2009-01-22
申请号：US12173328
申请日：2008-07-15
申请人： Hiroyuki Satake , Yuichiro Hashimoto , Yasuaki Takada
发明人： Hiroyuki Satake , Yuichiro Hashimoto , Yasuaki Takada
IPC分类号： B01D59/44
CPC分类号： H01J49/004 , H01J49/422 , H01J49/4255 , H01J49/427
摘要： A mass spectrometer includes a linear multipole electrode, an auxiliary electrode that applies a DC potential on the center axis of the linear multipole electrode, and a DC power supply that supplies a DC power to the auxiliary electrode. The DC potential slope formed on the center axis of the multipole electrode is changed according to the measuring condition. The ejection time of ions can be adjusted optimally by adjusting the potential slope so as to satisfy the measuring condition. If the ejection time of ions is shortened, confusion of different ion information items that might otherwise occur on a spectrum can be avoided. If the ejection time of ions is lengthened, detection limit exceeding can be avoided and ions can be measured efficiently, thereby highly efficient ion measurements are always assured.
摘要翻译：质谱仪包括线性多极电极，在线性多极电极的中心轴上施加直流电位的辅助电极和向辅助电极提供直流电力的直流电源。根据测量条件改变在多极电极的中心轴上形成的直流电位斜率。通过调整电位斜率以满足测量条件，可以最佳地调节离子的喷射时间。如果离子的喷射时间缩短，则可以避免在光谱上可能发生的不同离子信息项的混淆。如果离子的喷射时间延长，则可以避免超过检测极限，有效测量离子，从而确保高效的离子测量。

2. 发明授权

US08044349B2 Mass spectrometer 有权
标题翻译：质谱仪
公开(公告)号：US08044349B2
公开(公告)日：2011-10-25
申请号：US12173328
申请日：2008-07-15
申请人： Hiroyuki Satake , Yuichiro Hashimoto , Yasuaki Takada
发明人： Hiroyuki Satake , Yuichiro Hashimoto , Yasuaki Takada
IPC分类号： H01J49/00
CPC分类号： H01J49/004 , H01J49/422 , H01J49/4255 , H01J49/427
摘要： A mass spectrometer includes a linear multipole electrode, an auxiliary electrode that applies a DC potential on the center axis of the linear multipole electrode, and a DC power supply that supplies a DC power to the auxiliary electrode. The DC potential slope formed on the center axis of the multipole electrode is changed according to the measuring condition. The ejection time of ions can be adjusted optimally by adjusting the potential slope so as to satisfy the measuring condition. If the ejection time of ions is shortened, confusion of different ion information items that might otherwise occur on a spectrum can be avoided. If the ejection time of ions is lengthened, detection limit exceeding can be avoided and ions can be measured efficiently, thereby highly efficient ion measurements are always assured.
摘要翻译：质谱仪包括线性多极电极，在线性多极电极的中心轴上施加直流电位的辅助电极和向辅助电极提供直流电力的直流电源。根据测量条件改变在多极电极的中心轴上形成的直流电位斜率。通过调整电位斜率以满足测量条件，可以最佳地调节离子的喷射时间。如果离子的喷射时间缩短，则可以避免在光谱上可能发生的不同离子信息项的混淆。如果离子的喷射时间延长，则可以避免超过检测极限，有效测量离子，从而确保高效的离子测量。

3. 发明授权

US08164053B2 Mass analyzer and mass analyzing method 有权
标题翻译：质量分析仪和质量分析方法
公开(公告)号：US08164053B2
公开(公告)日：2012-04-24
申请号：US12039306
申请日：2008-02-28
申请人： Masuyuki Sugiyama , Yuichiro Hashimoto , Hideki Hasegawa , Yasuaki Takada
发明人： Masuyuki Sugiyama , Yuichiro Hashimoto , Hideki Hasegawa , Yasuaki Takada
IPC分类号： B01D59/44
CPC分类号： H01J49/0045
摘要： There has been a problem that both detection sensitivity and throughput cannot be improved simultaneously by a conventional MS/MS analysis method.A mass analyzer having an ion trap for ejecting ions in a specific mass range, a collisional dissociation part for causing ions ejected from the ion trap to be dissociated, a mass analyzing part for performing a mass analysis of ions ejected from the collisional dissociation part, and a control part including a list in which measurement conditions for each ion are stored selectively resonance-ejects ions introduced into and accumulated in the ion trap based on masses. A scanning operation is a repetition of an operation of ejecting specific precursor ions in a direction of the collisional dissociation part and an operation of ejecting nothing, and each ion can be measured under optimal measurement conditions by controlling an output voltage of each part with reference to list information, realizing a mass analyzer that can perform an MS/MS measurement with high throughput and high sensitivity.
摘要翻译：存在通过常规MS / MS分析方法不能同时改善检测灵敏度和通过量的问题。 1.一种质量分析装置，具有用于将特定质量范围的离子排出的离子阱，用于使从离子阱排出的离子离解的碰撞解离部，用于进行从碰撞解离部喷出的离子的质量分析的质量分析部，以及包括其中存储每个离子的测量条件的列表的控制部分选择性地基于质量共振 - 喷射引入和积聚在离子阱中的离子。扫描操作是重复在碰撞解离部分的方向上排出特定的前体离子的操作和不喷射的操作，并且可以在最佳测量条件下测量每个离子，通过参考每个部分的输出电压列表信息，实现能够以高吞吐量和高灵敏度执行MS / MS测量的质量分析器。

4. 发明授权

US07718960B2 Ion mobility spectrometer and ion-mobility-spectrometry/mass-spectrometry hybrid spectrometer 有权
标题翻译：离子迁移光谱仪和离子迁移光谱/质谱混合光谱仪
公开(公告)号：US07718960B2
公开(公告)日：2010-05-18
申请号：US12149737
申请日：2008-05-07
申请人： Yuichiro Hashimoto , Hideki Hasegawa , Masuyuki Sugiyama , Yasuaki Takada
发明人： Yuichiro Hashimoto , Hideki Hasegawa , Masuyuki Sugiyama , Yasuaki Takada
IPC分类号： H01J49/10 , H01J49/40
CPC分类号： G01N27/622
摘要： A low-cost and high-ion-transmission-ratio ion-mobility spectrometry filter, including an ion source, a first drift region in which a gas flow direction and a DC electric-field direction are opposite to each other, a second drift region in which a gas flow direction is provided, the gas flow direction being different from the gas flow direction in the first drift region, and being opposite to a DC electric-field application direction in the second drift region, an intermediate region having an electric field for causing ions to travel between the first drift region and the second drift region, and a detector for detecting ions which have passed through the first drift region and the second drift region.
摘要翻译：一种低成本和高离子透射率的离子迁移谱分析滤光器，包括离子源，气流方向和DC电场方向彼此相反的第一漂移区，第二漂移区其中设置有气体流动方向，气体流动方向与第一漂移区域中的气体流动方向不同，并且与第二漂移区域中的直流电场施加方向相反，具有电场的中间区域用于使离子在第一漂移区域和第二漂移区域之间行进;以及检测器，用于检测已经通过第一漂移区域和第二漂移区域的离子。

5. 发明申请

US20090065688A1 ANALYTICAL INSTRUMENT 有权
标题翻译：分析仪器
公开(公告)号：US20090065688A1
公开(公告)日：2009-03-12
申请号：US12037148
申请日：2008-02-26
申请人： Yuichiro Hashimoto , Hideki Hasegawa , Masuyuki Sugiyama , Yasuaki Takada
发明人： Yuichiro Hashimoto , Hideki Hasegawa , Masuyuki Sugiyama , Yasuaki Takada
IPC分类号： B01D59/44
CPC分类号： H01J49/0036
摘要： The present invention achieves accurate quantitative determination without reducing measurement throughput and also without having to add a multi-component reference standard. An analytical instrument of the present invention for determining the concentration of a target compound contained in a target sample includes: a means for ionizing a mixture having a specific compound added to the target sample; a means for performing mass analysis on resulting ions; and a database that stores dependence of signal intensity on the concentration of a specific matrix component for each of the target compound and the addition compound, wherein the database is used to calibrate the concentration of the target compound from a signal derived from the target compound and a signal derived from the addition compound, each signal obtained by the mass analysis means. The present invention achieves a multi-component analyzer using low-cost, high-throughput mass analysis, as compared to conventional technique.
摘要翻译：本发明可以在不降低测量吞吐量的情况下实现准确的定量测定，而且不必添加多组分参考标准。本发明的用于测定目标样品中包含的目标化合物浓度的分析仪包括：将具有特定化合物的混合物电离于目标样品的装置; 对所得离子进行质量分析的手段; 以及数据库，其存储信号强度对于每种目标化合物和加成化合物的特定基质成分的浓度的依赖性，其中所述数据库用于从源自目标化合物的信号校准目标化合物的浓度，以及来自加成化合物的信号，通过质量分析装置得到的各信号。与现有技术相比，本发明实现了使用低成本，高吞吐量质量分析的多分量分析仪。

6. 发明申请

US20090032697A1 MASS ANALYZER AND MASS ANALYZING METHOD 有权
标题翻译：质量分析仪和质量分析方法
公开(公告)号：US20090032697A1
公开(公告)日：2009-02-05
申请号：US12039306
申请日：2008-02-28
申请人： Masuyuki SUGIYAMA , Yuichiro Hashimoto , Hideki Hasegawa , Yasuaki Takada
发明人： Masuyuki SUGIYAMA , Yuichiro Hashimoto , Hideki Hasegawa , Yasuaki Takada
IPC分类号： B01D59/44
CPC分类号： H01J49/0045
摘要： There has been a problem that both detection sensitivity and throughput cannot be improved simultaneously by a conventional MS/MS analysis method.A mass analyzer having an ion trap for ejecting ions in a specific mass range, a collisional dissociation part for causing ions ejected from the ion trap to be dissociated, a mass analyzing part for performing a mass analysis of ions ejected from the collisional dissociation part, and a control part including a list in which measurement conditions for each ion are stored selectively resonance-ejects ions introduced into and accumulated in the ion trap based on masses. A scanning operation is a repetition of an operation of ejecting specific precursor ions in a direction of the collisional dissociation part and an operation of ejecting nothing, and each ion can be measured under optimal measurement conditions by controlling an output voltage of each part with reference to list information, realizing a mass analyzer that can perform an MS/MS measurement with high throughput and high sensitivity.
摘要翻译：存在通过常规MS / MS分析方法不能同时改善检测灵敏度和通过量的问题。 1.一种质量分析装置，具有用于在特定质量范围内排出离子的离子阱，用于使从离子阱排出的离子离解的碰撞解离部，对从碰撞解离部喷出的离子进行质量分析的质量分析部，以及包括其中存储每个离子的测量条件的列表的控制部分选择性地基于质量共振 - 喷射引入和积聚在离子阱中的离子。扫描操作是重复在碰撞解离部分的方向上排出特定的前体离子的操作和不喷射的操作，并且可以在最佳测量条件下测量每个离子，通过参考每个部分的输出电压列表信息，实现能够以高吞吐量和高灵敏度执行MS / MS测量的质量分析器。

7. 发明授权

US06423965B1 Mass spectrometer 有权
标题翻译：质谱仪
公开(公告)号：US06423965B1
公开(公告)日：2002-07-23
申请号：US09378767
申请日：1999-08-23
申请人： Yuichiro Hashimoto , Takayuki Nabeshima , Yasuaki Takada , Minoru Sakairi , Masamichi Tsukada
发明人： Yuichiro Hashimoto , Takayuki Nabeshima , Yasuaki Takada , Minoru Sakairi , Masamichi Tsukada
IPC分类号： H01J4900
CPC分类号： H01J49/04
摘要： Plasma ion source mass spectrometers or liquid chromatograph/mass spectrometers are provided: wherein photon noises and matrix molecule ions produced by the ion source are decreased, the decrease of the quantity of signal is suppressed, and the apparatus maintenance is improved. The photon noises are decreased with a shielding plate and a 90 degrees deflector. The maintainability in cleaning is improved by a combination of a leading electrode, the shielding plate having a small hole, and a gate valve. The decrease in the quantity of signal is suppressed with the leading electrode, and a double cylindrical type static lens. Position adjustment of the leading electrode is performed with a flat plate having plural holes. Using an ion trap mass analyzer, matrix molecule ions are eliminated by applying a resonance voltage between its end cap electrodes. Decrease in the quantity of signals, which has been a problem, can be prevented, and a high transmission can be realized with a preferable reproducibility against disturbance of an electric field caused by ion lens and the like. A detectable limit of atomic ions of the sample can be improved by eliminating the matrix molecule ions.
摘要翻译：提供了等离子体离子源质谱仪或液相色谱仪/质谱仪：其中由离子源产生的光子噪声和基质分子离子减少，抑制了信号量的减少，从而改善了设备的维护。光子噪声随屏蔽板和90度偏转器而减小。通过前导电极，具有小孔的屏蔽板和闸阀的组合来提高清洁的可维护性。用前导电极和双圆柱形静电透镜抑制信号量的减少。引导电极的位置调整用具有多个孔的平板进行。使用离子阱质量分析仪，通过在其端盖电极之间施加谐振电压来消除基质分子离子。可以防止已经存在问题的信号量的减少，并且以离子透镜等引起的电场干扰的优选再现性可以实现高透射率。可以通过消除基质分子离子来改善样品的原子离子的可检测极限。

8. 发明授权

US08835834B2 Mass spectrometer and mass spectrometry method 有权
标题翻译：质谱仪和质谱法
公开(公告)号：US08835834B2
公开(公告)日：2014-09-16
申请号：US13383371
申请日：2010-07-09
申请人： Masuyuki Sugiyama , Yuichiro Hashimoto , Hisashi Nagano , Hideki Hasegawa , Yasuaki Takada , Masuyoshi Yamada
发明人： Masuyuki Sugiyama , Yuichiro Hashimoto , Hisashi Nagano , Hideki Hasegawa , Yasuaki Takada , Masuyoshi Yamada
IPC分类号： B01D59/44 , H01J49/00
CPC分类号： H01J49/004
摘要： An object is to measure both cations and anions with high duty cycle. In a mass spectrometer comprising an ion source (1), an ion guide part (31), and an ion trap (32), while ions are being mass-selectively ejected from the ion trap, ions having a polarity reverse to that of the ions trapped in the ion trap are introduced into the ion guide part.
摘要翻译：一个目标是测量阳离子和阴离子高占空比。在离子源（1），离子引导部（31）和离子阱（32）的质谱仪中，离子从离子阱中质量选择性地喷出时，具有与捕获在离子阱中的离子被引入离子引导部。

9. 发明授权

US08560249B2 Dangerous substance detection system 有权
标题翻译：危险物质检测系统
公开(公告)号：US08560249B2
公开(公告)日：2013-10-15
申请号：US12903263
申请日：2010-10-13
申请人： Hisashi Nagano , Yasuaki Takada , Minoru Sakairi , Yuichiro Hashimoto , Masuyuki Sugiyama
发明人： Hisashi Nagano , Yasuaki Takada , Minoru Sakairi , Yuichiro Hashimoto , Masuyuki Sugiyama
IPC分类号： G01N31/00
CPC分类号： H01J49/0036 , G01N33/227 , H01J49/004
摘要： A method of quickly detecting a handmade explosive in a bottle with a low erroneous alarm frequency is provided. A sample gas generated from a bottle placed on a bottle placement space is sucked-in, and ions of the sample gas are generated by an ion source and subjected to mass analysis. The presence/absence of a mass spectrum derived from the handmade explosive is determined from an obtained mass spectrum, and the result thereof is displayed on a monitor, thereby quickly detecting the handmade explosive in the bottle or the handmade explosive adhering to the surface of the bottle at a low erroneous alarm frequency.
摘要翻译：提供了一种在低错误报警频率的瓶子中快速检测手工炸药的方法。将从放置在瓶放置空间的瓶子产生的样品气体吸入，并且通过离子源产生样品气体的离子并进行质量分析。从所获得的质谱确定来自手工炸药的质谱的存在/不存在，并将其结果显示在监视器上，从而快速检测瓶中的手工炸药或附着在表面上的手工炸药瓶子在低错误报警频率。

10. 发明申请

US20110093214A1 DANGEROUS SUBSTANCE DETECTION SYSTEM 有权
标题翻译：危险物质检测系统
公开(公告)号：US20110093214A1
公开(公告)日：2011-04-21
申请号：US12903263
申请日：2010-10-13
申请人： Hisashi NAGANO , Yasuaki Takada , Minoru Sakairi , Yuichiro Hashimoto , Masuyuki Sugiyama
发明人： Hisashi NAGANO , Yasuaki Takada , Minoru Sakairi , Yuichiro Hashimoto , Masuyuki Sugiyama
IPC分类号： G01N33/22 , H01J49/26
CPC分类号： H01J49/0036 , G01N33/227 , H01J49/004
摘要： A method of quickly detecting a handmade explosive in a bottle with a low erroneous alarm frequency is provided. A sample gas generated from a bottle placed on a bottle placement space is sucked-in, and ions of the sample gas are generated by an ion source and subjected to mass analysis. The presence/absence of a mass spectrum derived from the handmade explosive is determined from an obtained mass spectrum, and the result thereof is displayed on a monitor, thereby quickly detecting the handmade explosive in the bottle or the handmade explosive adhering to the surface of the bottle at a low erroneous alarm frequency.
摘要翻译：提供了一种在低错误报警频率的瓶子中快速检测手工炸药的方法。将从放置在瓶放置空间的瓶子产生的样品气体吸入，并且通过离子源产生样品气体的离子并进行质量分析。从所获得的质谱确定来自手工炸药的质谱的存在/不存在，并将其结果显示在监视器上，从而快速检测瓶中的手工炸药或附着在表面上的手工炸药瓶子在低错误报警频率。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式