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1. 发明授权

US4806367A Process for the production of a food material 失效
标题翻译：生产食品原料的方法
公开(公告)号：US4806367A
公开(公告)日：1989-02-21
申请号：US55523
申请日：1987-05-29
申请人： Hiroshi Kiuchi , Katsumi Murata , Kazuo Murakami , Isao Kusakabe , Hideyuki Kobayashi
发明人： Hiroshi Kiuchi , Katsumi Murata , Kazuo Murakami , Isao Kusakabe , Hideyuki Kobayashi
IPC分类号： A23L11/00 , A23C20/02 , A23J3/16 , A23J3/34 , A23L1/20 , A23J1/14
CPC分类号： A23C20/025 , A23J3/346
摘要： Soybean milk is treated with protease at a pH in the range which does not cause acid coagulation in the presence of a magnesium salt as a concentration in the range which does not substantially cause magnesium coagulation, to flocculate protein in soybean milk, thereby a food material having good mouthfeel and high processability may be obtained.
摘要翻译：在pH范围内用蛋白酶处理豆浆，在不存在镁盐的情况下，不会引起酸凝结的浓度，其浓度不会实质上引起镁凝结，絮凝豆浆中的蛋白质，从而使食品材料可以获得良好的口感和高加工性。

2. 发明授权

US4877622A Process for producing food material 失效
标题翻译：生产食品的方法
公开(公告)号：US4877622A
公开(公告)日：1989-10-31
申请号：US298287
申请日：1989-01-13
申请人： Hiroshi Kiuchi , Katsumi Murata , Kazuo Murakami , Isao Kusakabe , Hideyuki Kobayashi
发明人： Hiroshi Kiuchi , Katsumi Murata , Kazuo Murakami , Isao Kusakabe , Hideyuki Kobayashi
IPC分类号： A23C11/10 , A23J1/14 , A23J3/16 , A23J3/34 , A23L11/00
CPC分类号： A23J3/346
摘要： Protein obtained by coagulating soymilk with microbially produced protease within a pH range not causing acid coagulation and at a temperature higher than the optimum operation temperature of the protease provides food material of desirable flavor and high processability.
摘要翻译：通过在不引起酸凝结的pH范围内并且在高于蛋白酶的最佳操作温度的温度下用微生物产生的蛋白酶凝结豆浆获得的蛋白质提供了所需风味和高加工性的食品材料。

3. 发明授权

US5348875A Production of alginase from Enterobacter cloacae M-1 (FERM BP-2577) 失效
标题翻译：从阴沟肠杆菌M-1（FERM BP-2577）生产藻酸酶
公开(公告)号：US5348875A
公开(公告)日：1994-09-20
申请号：US132223
申请日：1993-10-06
申请人： Katsumi Murata , Kazuo Murakami , Isao Kusakabe , Toshihide Satoh
发明人： Katsumi Murata , Kazuo Murakami , Isao Kusakabe , Toshihide Satoh
IPC分类号： C12N9/88 , C12N9/24 , C12N1/00 , C12N1/12
CPC分类号： C12N9/88 , Y10S435/822
摘要： The present invention relates to alginase produced by bacteria belonging to the genus and a process for production thereof and bacteria as well as a method for decomposing alginic acid.
摘要翻译：本发明涉及由属于该属的细菌产生的藻酸酶及其生产方法和细菌以及分解藻酸的方法。

4. 发明授权

US06723704B2 Sphingoglycolipid 失效
标题翻译：鞘氨醇
公开(公告)号：US06723704B2
公开(公告)日：2004-04-20
申请号：US09894140
申请日：2001-06-29
申请人： Kazuyoshi Kawahara , Katsumi Murata
发明人： Kazuyoshi Kawahara , Katsumi Murata
IPC分类号： A61K31702
CPC分类号： C07H15/10 , A61K8/68 , A61Q1/02 , A61Q1/04 , A61Q1/06 , A61Q1/10 , A61Q5/02 , A61Q5/065 , A61Q9/02 , A61Q19/00 , A61Q19/02 , A61Q19/10 , C07H15/04 , C07H15/18
摘要： A glycosphingolipid having a sugar chain containing &agr;-glucosamine and &bgr;-glucosamine is disclosed. Such glycosphingolipid is advantageous in that possibly being manufactured in a facile and inexpensive manner, and that exhibiting moisturizing effect and immuno-enhancing activity.
摘要翻译：公开了具有含有α-葡糖胺和β-葡糖胺糖链的糖鞘脂。这样的鞘糖脂的优点在于可以以容易且廉价的方式制造，并且具有保湿作用和免疫增强活性。

5. 发明授权

US06514744B2 External compositions for skin comprising sphingoglycolipid 失效
标题翻译：用于皮肤的外用组合物包含鞘糖脂
公开(公告)号：US06514744B2
公开(公告)日：2003-02-04
申请号：US10012510
申请日：2001-12-12
申请人： Katsumi Murata , Takashi Nozawa , Hisako Hara , Michiki Asai , Sachio Wakayama
发明人： Katsumi Murata , Takashi Nozawa , Hisako Hara , Michiki Asai , Sachio Wakayama
IPC分类号： C12N120
CPC分类号： C12N1/14 , A61K8/0212 , A61K8/68 , A61K8/97 , A61K8/9706 , A61K8/99 , A61K2800/872 , A61Q1/02 , A61Q1/04 , A61Q1/06 , A61Q1/08 , A61Q1/10 , A61Q5/00 , A61Q5/02 , A61Q5/065 , A61Q9/02 , A61Q19/00 , A61Q19/02 , A61Q19/10 , Y10S435/822
摘要： A sphingoglycolipid represented by the following formula: obtained from a bacterium of the genus Sphingomonas, further from the species paucimobilis, capsulate or adhaesiva, after being washed with acetone and then extracted with alcohol or alcohol-water mixture. R1 represents a sugar portion of a single uronic acid or one to four hexoses of uronic acid, glucosamine, galactose and/or mannose; R2 represents an alkyl group which may have a cycloalkyl group, an alkenyl group or an alkynyl group; and R3 represents an alkyl group.
摘要翻译：由下式表示的神经鞘糖脂：从鞘氨醇单胞菌属细菌获得，进一步从类胡椒，包囊或adhaesiva，用丙酮洗涤，然后用醇或醇 - 水混合物萃取。 R1表示单一糖醛酸或一至四个糖醛酸，葡糖胺，半乳糖和/或甘露糖的己糖的糖部分; R 2表示可以具有环烷基，烯基或炔基的烷基; 并且R 3表示烷基。

6. 发明授权

US06348201B2 External composition for skin comprising sphingoglycolipid 失效
标题翻译：皮肤外用组合物，含有鞘糖脂
公开(公告)号：US06348201B2
公开(公告)日：2002-02-19
申请号：US09084394
申请日：1998-05-27
申请人： Katsumi Murata , Takashi Nozawa , Hisako Hara , Michiki Asai , Sachio Wakayama
发明人： Katsumi Murata , Takashi Nozawa , Hisako Hara , Michiki Asai , Sachio Wakayama
IPC分类号： A61K700
CPC分类号： C12N1/14 , A61K8/0212 , A61K8/68 , A61K8/97 , A61K8/9706 , A61K8/99 , A61K2800/872 , A61Q1/02 , A61Q1/04 , A61Q1/06 , A61Q1/08 , A61Q1/10 , A61Q5/00 , A61Q5/02 , A61Q5/065 , A61Q9/02 , A61Q19/00 , A61Q19/02 , A61Q19/10 , Y10S435/822
摘要： The present application discloses an external composition for skin comprising a component obtaind by washing a bacterium of the genus Sphingomonas with acetone and then extracting the resultant with alcohol or alcohol-water mixture; an external composition for skin comprising a component extracted from a white bacterium of the genus Sphingomonas; and an external composition for skin comprising a sphingoglycolipid represented by the following formula: where, R1 represents a sugar portion consisting of a single uronic acid or one to four hexoses selected from a group consisting of uronic acid, glucosamine, galactose and mannose; R2 represents an alkyl group which may have a cycloalkyl group, an alkenyl group or an alkynyl group; and R3 represents an alkyl group; these alkyl, alkenyl and alkynyl groups being straight or branched, and substituted or unsubstituted. These external compositions for skin exhibit excellent moisturizing and skin roughnes prevention effects.
摘要翻译：本申请公开了一种用于皮肤的外用组合物，其包含通过用丙酮洗涤鞘氨醇单胞菌属细菌获得的组分，然后用醇或醇 - 水混合物萃取所得物; 用于皮肤的外用组合物，其包含从鞘氨醇单胞菌属的白细菌提取的成分; 皮肤外用组合物，其含有由下式表示的鞘糖脂：其中，R1表示由单一糖醛酸或1〜4个选自由糖醛酸，葡糖胺，半乳糖和甘露糖组成的组的己糖组成的糖部分; R 2表示可以具有环烷基，烯基或炔基的烷基; R3代表烷基; 这些烷基，烯基和炔基是直链或支链的，并且是取代或未取代的。这些皮肤外用组合物表现出优异的保湿和皮肤粗糙度防止效果。

7. 发明授权

US06306915B1 Methods of making an emulsified composition 有权
标题翻译：乳化组合物的制备方法
公开(公告)号：US06306915B1
公开(公告)日：2001-10-23
申请号：US09370211
申请日：1999-08-09
申请人： Katsumi Murata
发明人： Katsumi Murata
IPC分类号： B01F308
CPC分类号： A61K8/68 , A61K8/06 , A61Q19/00 , A61Q19/10 , Y10S514/938 , Y10S514/939 , Y10S516/925 , Y10S516/926
摘要： The present invention provides a method of making an emulsified composition employing an emulsifier containing a sphingoglycolipid which has a structure represented by the following formula: wherein R1 is a saccharide moiety which consists of three to four hexoses selected from the group consisting of uronic acid, glucosamine, galactose, and mannose, or one uronic acid; R2 is an alkyl group, which may have a cycloalkyl group, an alkenyl group, or an alkynyl group; and R3 is an alkyl group. The alkyl group, the alkenyl group and the alkynyl group may have a normal chain or a branched chain, and may be substituted or unsubstituted. The emulsifier of the present invention has marked moisturizing effect, skin roughening preventing effect, and emulsifying effect.
摘要翻译：本发明提供一种使用含有鞘糖脂的乳化剂的乳化组合物的制造方法，所述乳化剂具有由下式表示的结构：其中，R1是由三至四种己糖组成的糖部分，所述糖部分选自糖醛酸，葡糖胺，半乳糖和甘露糖，或一种糖醛酸; R2是可以具有环烷基，烯基或炔基的烷基; R3为烷基。烷基，烯基和炔基可以具有正链或支链，并且可以是取代或未取代的。本发明的乳化剂具有显着的保湿作用，皮肤粗糙化防止效果和乳化作用。

8. 发明申请

US20060269524A1 Composition for nkt cell activation 审中-公开
标题翻译： nkt细胞活化的组成
公开(公告)号：US20060269524A1
公开(公告)日：2006-11-30
申请号：US10553695
申请日：2005-02-21
申请人： Yoshio Kumazawa , Katsumi Murata , Kazuyoshi Kawahara , Hiroaki Takimoto
发明人： Yoshio Kumazawa , Katsumi Murata , Kazuyoshi Kawahara , Hiroaki Takimoto
IPC分类号： A61K35/14 , A61K31/739
CPC分类号： A61K31/7012
摘要： Provided is more effective a cell activator. A cell activator comprising a glycosphingolipid having a structure represented by the following formula (1): formula (1) wherein R1 represents the following formula (1-1): formula (1-1) wherein R3 represents alkyl or alkenyl and R4 represents alkyl; and R2 represents hydrogen, or α-galactose, α-glucose, α-mannose, α-glucosamine, β-glucosamine or a combination thereof.
摘要翻译：提供更有效的细胞活化剂。包含具有下式（1）所示结构的鞘糖脂的细胞活化剂：式（1）其中R 1表示下式（1-1）：式（1-1）其中R 3是代表烷基或烯基，R 4表示烷基; R 2表示氢或α-半乳糖，α-葡萄糖，α-甘露糖，α-葡糖胺，β-葡糖胺或其组合。

9. 发明申请

US20110104248A1 LIPOSOMES AND IMMUNOPOTENTIATING COMPOSITIONS CONTAINING THE SAME 审中-公开
标题翻译：脂质体和含有其的免疫组合物
公开(公告)号：US20110104248A1
公开(公告)日：2011-05-05
申请号：US12301965
申请日：2008-03-24
申请人： Yoshio Kumazawa , Hiroaki Takimoto , Joe Inoue , Masahiro Kubota , Takashi Nozawa , Katsumi Murata
发明人： Yoshio Kumazawa , Hiroaki Takimoto , Joe Inoue , Masahiro Kubota , Takashi Nozawa , Katsumi Murata
IPC分类号： A61K31/7032 , A61K9/127 , A61K39/00 , A61P37/02 , A61P35/00 , A61P31/12 , A61P37/08
CPC分类号： A61K9/1272 , A61K39/39 , A61K2039/55555
摘要： It is an object to enhance immunopotentiating activity of a glycosphingolipid.A liposome, comprising at least one type of glycosphingolipid represented by the following Formula (1) inside and/or outside a lipid membrane:
摘要翻译：目的是提高糖鞘蛋白的免疫增强活性。一种脂质体，其包含在脂质膜的内部和/或外部由下式（1）表示的至少一种类型的鞘糖脂：

10. 发明申请

US20100008878A1 PROPYLENE GLYCOL HYALURONATE, AND SKINCARE PREPARATION FOR EXTERNAL USE COMPRISING SAME 审中-公开
标题翻译：丙烯酸羟丙酯，外用皮肤护理品的制备
公开(公告)号：US20100008878A1
公开(公告)日：2010-01-14
申请号：US12444889
申请日：2008-08-01
申请人： Hideki Hirai , Makoto Watanabe , Takashi Nozawa , Katsumi Murata
发明人： Hideki Hirai , Makoto Watanabe , Takashi Nozawa , Katsumi Murata
IPC分类号： A61K8/73 , C07H3/00 , A61Q19/02
CPC分类号： A61K47/36 , A61K8/735 , A61Q1/00 , A61Q1/04 , A61Q1/06 , A61Q1/08 , A61Q1/10 , A61Q1/12 , A61Q19/00 , A61Q19/02 , A61Q19/10 , C08B37/0072 , C08L5/08
摘要： A propylene glycol hyaluronate having an esterification degree of from 10 to 90% and a limiting viscosity of less than 3 dL/g has an excellent percutaneous absorption-promoting effect, and is widely usable as cosmetics and pharmaceutical products.
摘要翻译：酯化度为10〜90％，特性粘度小于3dL / g的丙二醇透明质酸酯具有优异的经皮吸收促进效果，广泛用作化妆品和药品。

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