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1. 发明授权

US06900446B2 Charged particle beam irradiation equipment and control method thereof 失效
标题翻译：带电粒子束照射设备及其控制方法
公开(公告)号：US06900446B2
公开(公告)日：2005-05-31
申请号：US10287656
申请日：2002-11-05
申请人： Hiroshi Akiyama , Hiroshi Kubo , Kazuo Hiramoto
发明人： Hiroshi Akiyama , Hiroshi Kubo , Kazuo Hiramoto
IPC分类号： A61N5/10 , G01Q10/00 , G01Q60/00 , G01Q60/50 , G09G3/10 , G21K1/08 , G21K1/093 , G21K5/00 , H01J7/28 , H05H7/04
CPC分类号： H05H7/04 , A61N5/10 , A61N5/1043 , A61N2005/1087 , G21K1/093
摘要： A power supply for applying a voltage to a scanning electromagnet for deflecting a charged particle beam has a first power supply unit having no filter and a second power supply unit having a filter. When an irradiation position of the charged particle beam in an irradiation object is moved, the first power supply unit, namely a power supply unit having no filter, is used to apply the voltage to the scanning electromagnet, so that an exciting current flowing in the scanning electromagnet can be changed in a short time. Further, when the irradiation position of the charged particle beam is maintained, the second power supply is used to apply a voltage whose pulsating component was removed to the scanning electromagnet, so that the exciting current flowing in the scanning electromagnet can be controlled precisely. Consequently, the charged particle beam can be applied uniformly to the irradiation object and an irradiation time of the charged particle beam to the irradiation object can be curtailed.
摘要翻译：用于向扫描电磁体施加电压以使带电粒子束偏转的电源具有不具有滤波器的第一电源单元和具有滤波器的第二电源单元。当照射物体中的带电粒子束的照射位置移动时，使用第一电源单元即不具有滤波器的电源单元将电压施加到扫描电磁体，使得在扫描电磁铁可以在短时间内改变。此外，当保持带电粒子束的照射位置时，使用第二电源将脉冲分量除去的电压施加到扫描电磁体，使得可以精确地控制在扫描电磁体中流动的激励电流。因此，可以将带电粒子束均匀地施加到照射物体，并且可以减少带电粒子束对照射物体的照射时间。

2. 发明授权

US06881970B2 Charged particle beam irradiation equipment and control method thereof 失效
公开(公告)号：US06881970B2
公开(公告)日：2005-04-19
申请号：US10716472
申请日：2003-11-20
申请人： Hiroshi Akiyama , Hiroshi Kubo , Kazuo Hiramoto
发明人： Hiroshi Akiyama , Hiroshi Kubo , Kazuo Hiramoto
IPC分类号： A61N5/10 , G01Q10/00 , G01Q60/00 , G01Q60/50 , G09G3/10 , G21K1/08 , G21K1/093 , G21K5/00 , H01J7/28 , H05H7/04 , G01M23/00
CPC分类号： H05H7/04 , A61N5/10 , A61N5/1043 , A61N2005/1087 , G21K1/093
摘要： A power supply for applying a voltage to a scanning electromagnet for deflecting a charged particle beam has a first power supply unit having no filter and a second power supply unit having a filter. When an irradiation position of the charged particle beam in an irradiation object is moved, the first power supply unit, namely a power supply unit having no filter, is used to apply the voltage to the scanning electromagnet, so that an exciting current flowing in the scanning electromagnet can be changed in a short time. Further, when the irradiation position of the charged particle beam is maintained, the second power supply is used to apply a voltage whose pulsating component was removed to the scanning electromagnet, so that the exciting current flowing in the scanning electromagnet can be controlled precisely. Consequently, the charged particle beam can be applied uniformly to the irradiation object and an irradiation time of the charged particle beam to the irradiation object can be curtailed.

3. 发明授权

US06903351B1 Charged particle beam irradiation equipment having scanning electromagnet power supplies 有权
标题翻译：具有扫描电磁铁电源的带电粒子束照射设备
公开(公告)号：US06903351B1
公开(公告)日：2005-06-07
申请号：US09623040
申请日：1999-09-27
申请人： Hiroshi Akiyama , Hiroshi Kubo , Kazuo Hiramoto
发明人： Hiroshi Akiyama , Hiroshi Kubo , Kazuo Hiramoto
IPC分类号： A61N5/10 , G01Q10/00 , G01Q60/00 , G01Q60/50 , G09G3/10 , G21K1/08 , G21K1/093 , G21K5/00 , H01J7/28 , H05H7/04 , G01M23/00
CPC分类号： H05H7/04 , A61N5/10 , A61N5/1043 , A61N2005/1087 , G21K1/093
摘要： A power supply for applying a voltage to a scanning electromagnet for deflecting a charged particle beam has a first power supply unit having no filter and a second power supply unit having a filter. When an irradiation position of the charged particle beam in an irradiation object is moved, the first power supply unit, namely a power supply unit having no filter, is used to apply the voltage to the scanning electromagnet, so that an exciting current flowing in the scanning electromagnet can be changed in a short time. Further, when the irradiation position of the charged particle beam is maintained, the second power supply is used to apply a voltage whose pulsating component was removed to the scanning electromagnet, so that the exciting current flowing in the scanning electromagnet can be controlled precisely. Consequently, the charged particle beam can be applied uniformly to the irradiation object and an irradiation time of the charged particle beam to the irradiation object can be curtailed.
摘要翻译：用于向扫描电磁体施加电压以使带电粒子束偏转的电源具有不具有滤波器的第一电源单元和具有滤波器的第二电源单元。当照射物体中的带电粒子束的照射位置移动时，使用第一电源单元即不具有滤波器的电源单元将电压施加到扫描电磁体，使得在扫描电磁铁可以在短时间内改变。此外，当保持带电粒子束的照射位置时，使用第二电源将脉冲分量除去的电压施加到扫描电磁体，使得能够精确地控制在扫描电磁体中流动的励磁电流。因此，可以将带电粒子束均匀地施加到照射物体，并且可以减少带电粒子束对照射物体的照射时间。

4. 发明授权

US07825388B2 Charged particle beam irradiation system and charged particle beam extraction method 有权
标题翻译：带电粒子束照射系统和带电粒子束提取方法
公开(公告)号：US07825388B2
公开(公告)日：2010-11-02
申请号：US11678300
申请日：2007-02-23
申请人： Hideaki Nihongi , Koji Matsuda , Kazuo Hiramoto , Hiroshi Akiyama
发明人： Hideaki Nihongi , Koji Matsuda , Kazuo Hiramoto , Hiroshi Akiyama
IPC分类号： H05H9/00
CPC分类号： G21K1/10 , A61N5/1048 , A61N5/1065 , A61N2005/1087 , A61N2005/1095 , A61N2005/1096 , H05H7/10
摘要： A charged particle beam irradiation system and a charged particle beam extraction method which can prevent erroneous irradiation of a charged particle beam in the direction of advance of the charged particle beam. The system and method are featured in stopping supply of an ion beam to one or more of a plurality of angle zones in each of which a target dose is attained, the angle zones being formed by dividing an RMW in a rotating direction thereof, and in allowing the supply of the ion beam to one or more other angle zones in each of which a target dose is not yet attained. The invention can easily adjust beam doses at various positions in an affected part of the patient body in the direction of advance of the ion beam, and can greatly reduce the probability of erroneous irradiation that the beam dose becomes excessive or deficient at the various positions within the affected part of the patient body in the direction of advance of the ion beam.
摘要翻译：带电粒子束照射系统和带电粒子束提取方法，其可以防止带电粒子束沿着带电粒子束的前进方向的错误照射。该系统和方法的特征在于停止向多个角区域中的一个或多个角度区域供应目标剂量，其中角度区域通过沿其旋转方向分割RMW而形成，并且在允许将离子束供应到一个或多个其他角度区域，其中每个角度区域中尚未获得目标剂量。本发明可以容易地在离子束前进方向上调整患者身体的受影响部位的各个位置处的光束剂量，并且可以大大降低光束剂量在各种位置内过度或不足的错误照射的可能性患者身体的受影响部分在离子束前进方向。

5. 发明授权

US07589334B2 Ion beam delivery equipment and an ion beam delivery method 有权
标题翻译：离子束输送设备和离子束输送方法
公开(公告)号：US07589334B2
公开(公告)日：2009-09-15
申请号：US11714219
申请日：2007-03-06
申请人： Kazuo Hiramoto , Hiroshi Akiyama , Masaki Yanagisawa , Hisataka Fujimaki , Alfred Smith , Wayne Newhauser
发明人： Kazuo Hiramoto , Hiroshi Akiyama , Masaki Yanagisawa , Hisataka Fujimaki , Alfred Smith , Wayne Newhauser
IPC分类号： G21G5/00
CPC分类号： A61N5/10 , A61N2005/1087 , A61N2005/1095 , G21K5/04 , H05H7/04
摘要： The invention is intended to increase the number of patients treatable using one wheel having a thickness varied in the rotating direction to change energy of an ion beam passing the wheel. Ion beam delivery equipment for irradiating an ion beam to a patient for treatment comprises a beam generator for producing and accelerating the ion beam, an beam delivery nozzle including a range modulation wheel which has a predetermined thickness distribution in the rotating direction and is rotated on a travel passage of the ion beam generated from the beam generator to control a range of the ion beam, and an irradiation controller for controlling the beam producing and accelerating operation of the beam generator in accordance with the phase of rotation of the range modulation wheel.
摘要翻译：本发明旨在增加使用具有在旋转方向上变化的厚度的一个车轮来治疗的患者数量，以改变通过车轮的离子束的能量。用于将离子束照射到患者进行治疗的离子束输送设备包括用于产生和加速离子束的束发生器，包括在旋转方向上具有预定厚度分布并在旋转方向上旋转的范围调制轮的束输送喷嘴从光束发生器产生的离子束的行进通过，以控制离子束的范围;以及照射控制器，用于根据范围调制轮的旋转相位控制光束发生器的光束产生和加速操作。

6. 发明授权

US07576342B2 Ion beam delivery equipment and ion beam delivery method 有权
标题翻译：离子束输送设备和离子束输送方法
公开(公告)号：US07576342B2
公开(公告)日：2009-08-18
申请号：US11758755
申请日：2007-06-06
申请人： Kazuo Hiramoto , Hiroshi Akiyama , Masaki Yanagisawa , Hisataka Fujimaki , Alfred P. Smith , Wayne Newhauser
发明人： Kazuo Hiramoto , Hiroshi Akiyama , Masaki Yanagisawa , Hisataka Fujimaki , Alfred P. Smith , Wayne Newhauser
IPC分类号： A61N5/01 , A61N5/00 , H01J37/08
CPC分类号： A61N5/10 , A61N2005/1087 , A61N2005/1095 , G21K5/04 , H05H7/04
摘要： The invention is intended to increase the number of patients treatable using one wheel having a thickness varied in the rotating direction to change energy of an ion beam passing the wheel. Ion beam delivery equipment for irradiating an ion beam to a patient for treatment comprises a beam generator for producing and accelerating the ion beam, an beam delivery nozzle including a range modulation wheel which has a predetermined thickness distribution in the rotating direction and is rotated on a travel passage of the ion beam generated from the beam generator to control a range of the ion beam, and an irradiation controller for controlling the beam producing and accelerating operation of the beam generator in accordance with the phase of rotation of the range modulation wheel.
摘要翻译：本发明旨在增加使用具有在旋转方向上变化的厚度的一个车轮来治疗的患者数量，以改变通过车轮的离子束的能量。用于将离子束照射到患者进行治疗的离子束输送设备包括用于产生和加速离子束的束发生器，包括在旋转方向上具有预定厚度分布并在旋转方向上旋转的范围调制轮的束输送喷嘴从光束发生器产生的离子束的行进通过，以控制离子束的范围;以及照射控制器，用于根据范围调制轮的旋转相位控制光束发生器的光束产生和加速操作。

7. 发明授权

US07456415B2 Charged particle beam extraction system and method 有权
标题翻译：带电粒子束提取系统及方法
公开(公告)号：US07456415B2
公开(公告)日：2008-11-25
申请号：US11392687
申请日：2006-03-30
申请人： Masaki Yanagisawa , Kazuo Hiramoto , Hiroshi Akiyama
发明人： Masaki Yanagisawa , Kazuo Hiramoto , Hiroshi Akiyama
IPC分类号： A61N5/00
CPC分类号： A61N5/10 , A61N2005/1087 , A61N2005/1095 , G21K5/04 , H05H7/10
摘要： A ridge filter or a range modulation wheel (RMW) is formed to have a shape corresponding to an affected part in the patient body. A plurality of spread-out Bragg peaks with the same dose or different doses are formed in the affected part by executing beam-on/off control of the RMW, beam current control with rotation of the RMW, intensity modulation control, or scanning irradiation. As an alternative, a spread-out Bragg peak containing a portion with a different dose is formed. A treatment time is cut.
摘要翻译：脊状过滤器或范围调制轮（RMW）被形成为具有与患者体内的受影响部分相对应的形状。通过执行RMW的束开/关控制，RMW的旋转，强度调制控制或扫描照射，在受影响的部分中形成具有相同剂量或不同剂量的多个展开的布拉格峰。作为替代，形成包含具有不同剂量的部分的展开布拉格峰。治疗时间缩短。

8. 发明申请

US20060163495A1 Ion beam therapy system and its couch positioning method 有权
标题翻译：离子束治疗系统及其沙发定位方法
公开(公告)号：US20060163495A1
公开(公告)日：2006-07-27
申请号：US11039959
申请日：2005-01-24
申请人： Kazuo Hiramoto , Hiroshi Akiyama , Yoshihiko Nagamine , Alfred Smith , Wayne Newhauser
发明人： Kazuo Hiramoto , Hiroshi Akiyama , Yoshihiko Nagamine , Alfred Smith , Wayne Newhauser
IPC分类号： A61N5/01 , A61N5/10
CPC分类号： A61N5/1049 , A61N5/1069 , A61N2005/1061 , A61N2005/1087
摘要： A therapy system using an ion beam, which can shorten the time required for positioning a couch (patient). The therapy system using the ion beam comprises a rotating gantry provided with an ion beam delivery unit including an X-ray tube. An X-ray detecting device having a plurality of X-ray detectors can be moved in the direction of a rotation axis of the rotating gantry. A couch on which a patient is lying is moved until a tumor substantially reaches an extension of an ion beam path in the irradiating unit. The X-ray tube is positioned on the ion beam path and the X-ray detecting device is positioned on the extension of the ion beam path. With rotation of the rotating gantry, both the X-ray tube emitting an X-ray and the X-ray detecting device revolve around the patient. The X-ray is emitted to the patient and detected by the X-ray detectors after penetrating the patient. Tomographic information of the patient is formed based on signals outputted from the X-ray detectors. Information for positioning the couch is generated by using the tomographic information.
摘要翻译：使用离子束的治疗系统，可以缩短定位沙发（患者）所需的时间。使用离子束的治疗系统包括设置有包括X射线管的离子束输送单元的旋转台架。具有多个X射线检测器的X射线检测装置能够沿旋转机架的旋转轴线的方向移动。将患者躺在其上的沙发移动直到肿瘤基本上到达照射单元中的离子束路径的延伸。 X射线管位于离子束路径上，X射线检测装置位于离子束路径的延伸部上。通过旋转机架的旋转，发射X射线的X射线管和X射线检测装置都围绕患者转动。 X射线发射到患者身上，并在穿透患者后由X射线检测器进行检测。基于从X射线检测器输出的信号形成病人的层析信息。通过使用层析信息生成用于定位沙发的信息。

9. 发明授权

US06316776B1 Charged particle beam apparatus and method for operating the same 有权
标题翻译：带电粒子束装置及其操作方法
公开(公告)号：US06316776B1
公开(公告)日：2001-11-13
申请号：US09388437
申请日：1999-09-02
申请人： Kazuo Hiramoto , Hiroshi Akiyama , Koji Matsuda , Tetsuro Norimine , Masahiro Tadokoro
发明人： Kazuo Hiramoto , Hiroshi Akiyama , Koji Matsuda , Tetsuro Norimine , Masahiro Tadokoro
IPC分类号： H05H900
CPC分类号： A61N5/1042 , A61N5/1049 , A61N2005/1087 , A61N2005/1095
摘要： A method of irradiation with a charged particle beam and an irradiation apparatus wherein the charged particle beam supplied from an accelerator and extracted from the irradiation apparatus. The irradiation apparatus includes an electromagnet for scanning with the charged particle beam. The method includes the steps of stopping the extraction of the charged particle beam from the irradiation apparatus, changing an irradiation point of the charged particle beam by controlling the electromagnet under a condition when the extraction is stopped, and resuming the extraction of the charged particle beam from the irradiation apparatus after changing the irradiation point.
摘要翻译：一种带电粒子束照射的方法和照射装置，其中从加速器提供并从照射装置中提取的带电粒子束。照射装置包括用于用带电粒子束扫描的电磁体。该方法包括以下步骤：停止从照射装置提取带电粒子束，通过在提取停止的条件下控制电磁体来改变带电粒子束的照射点，并恢复提取带电粒子束改变照射点后从照射装置。

10. 发明授权

US08253113B2 Charged particle beam irradiation system and charged particle beam extraction method 有权
标题翻译：带电粒子束照射系统和带电粒子束提取方法
公开(公告)号：US08253113B2
公开(公告)日：2012-08-28
申请号：US12490696
申请日：2009-06-24
申请人： Hideaki Nishiuchi , Kazuyoshi Saito , Masahiro Tadokoro , Hiroshi Akiyama , Kazuo Hiramoto
发明人： Hideaki Nishiuchi , Kazuyoshi Saito , Masahiro Tadokoro , Hiroshi Akiyama , Kazuo Hiramoto
IPC分类号： G21K5/04
CPC分类号： A61N5/10 , A61N2005/1087 , H05H7/10 , H05H13/04
摘要： A charged particle beam irradiation system includes a synchrotron which accelerates an ion beam, an irradiation apparatus for irradiating an object with the ion beam introduced from the synchrotron, detection means for measuring an amount of accumulated charge of the ion beam that orbits in the synchrotron immediately before an extraction control period in an operating cycle of the synchrotron, and beam extraction control means for controlling extraction of the ion beam based on the measurement result of the accumulated beam charge amount so that extraction of a total amount of the ion beam is to be completed with an expiration of an extraction control time, the extraction control time representing a length of the extraction control period of the synchrotron and being set in advance.
摘要翻译：带电粒子束照射系统包括加速离子束的同步加速器，用于从同步加速器引入的离子束照射物体的照射装置，用于测量在同步加速器中轨道运动的离子束的累积电荷量的检测装置在同步加速器的操作循环中的提取控制期间之前，以及根据累积的光束电荷量的测量结果控制离子束的提取的光束提取控制装置，使得离子束的总量的提取为在提取控制时间到期时完成，提取控制时间表示同步加速器的提取控制周期的长度，并且预先设定。

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