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1. 发明申请

US20100136110A1 GRANULAR PHARMACEUTICAL COMPOSITION FOR ORAL ADMINISTRATION 审中-公开
标题翻译：用于口腔管理的颗粒药物组合物
公开(公告)号：US20100136110A1
公开(公告)日：2010-06-03
申请号：US12568257
申请日：2009-09-28
申请人： Hiroaki Tasaki , Atsushi Maeda , Takeshi Yano , Kazuhiro Sako
发明人： Hiroaki Tasaki , Atsushi Maeda , Takeshi Yano , Kazuhiro Sako
IPC分类号： A61K9/20 , A61K9/16
CPC分类号： A61K9/0056
摘要： A granular pharmaceutical composition for oral administration, wherein a drug-containing particle is coated with a coating comprising a methyl methacrylate-butyl methacrylate-dimethylaminoethyl methacrylate copolymer and a water-soluble polymer is disclosed.
摘要翻译：公开了一种用于口服给药的粒状药物组合物，其中含有药物的颗粒用包含甲基丙烯酸甲酯 - 甲基丙烯酸丁酯 - 甲基丙烯酸二甲氨基乙酯共聚物和水溶性聚合物的涂层涂覆。

2. 发明授权

US09050249B2 Oral pharmaceutical compositions in timed-release particle form and fast-disintegrating tablets containing this composition 有权
标题翻译：定时释放颗粒形式的口服药物组合物和含有该组合物的快速崩解片剂
公开(公告)号：US09050249B2
公开(公告)日：2015-06-09
申请号：US11119460
申请日：2005-04-28
申请人： Takayuki Yoshida , Hiroaki Tasaki , Masataka Katsuma , Atsushi Maeda
发明人： Takayuki Yoshida , Hiroaki Tasaki , Masataka Katsuma , Atsushi Maeda
IPC分类号： A61K9/16 , A61K31/135 , A61K47/02 , A61K47/04 , A61K47/10 , A61K47/12 , A61K47/18 , A61K47/24 , A61K47/26 , A61K47/32 , A61K47/34 , A61K47/36 , A61K47/38 , A61K47/40 , A61K47/42 , A61K9/00 , A61K9/20 , A61K9/50
CPC分类号： A61K9/0056 , A61K9/2077 , A61K9/2081 , A61K9/2095 , A61K9/501 , A61K9/5015 , A61K9/5026 , A61K9/5042 , A61K9/5047 , A61K9/5078 , A61K31/135
摘要： The present invention relates to an oral pharmaceutical composition in particle form, which comprises particles that contain a drug at the core of the pharmaceutical composition in particle form; a middle layer that contains two types of water-soluble components, an insolubilizer and an insolubilizing substance; and an outer layer for controlling water penetration that contains a water-insoluble substance. The present invention makes it possible to provide a pharmaceutical composition in particle form for oral use with which initial drug release is suppressed, the drug is quickly released thereafter, and lag time can be controlled as needed, and fast-disintegrating tablets containing this composition.
摘要翻译：本发明涉及一种颗粒形式的口服药物组合物，其包含以粒子形式含有药物组合物核心的药物的颗粒; 含有两种水溶性组分的中间层，不溶物和不溶物质; 以及用于控制含水不溶性物质的水渗透的外层。本发明使得可以提供一种用于口服使用的颗粒形式的药物组合物，其中抑制初始药物释放，此后快速释放药物，并且可以根据需要控制滞后时间，以及含有该组合物的快速崩解片剂。

3. 发明申请

US20050287211A1 Oral pharmaceutical compositions in timed-release particle form and fast-disintegrating tablets containing this composition 有权
标题翻译：定时释放颗粒形式的口服药物组合物和含有该组合物的快速崩解片剂
公开(公告)号：US20050287211A1
公开(公告)日：2005-12-29
申请号：US11119460
申请日：2005-04-28
申请人： Takayuki Yoshida , Hiroaki Tasaki , Masataka Katsuma , Atsushi Maeda
发明人： Takayuki Yoshida , Hiroaki Tasaki , Masataka Katsuma , Atsushi Maeda
IPC分类号： A61K9/00 , A61K9/16 , A61K9/20 , A61K9/26 , A61K9/50 , A61K31/135 , A61K47/02 , A61K47/04 , A61K47/10 , A61K47/12 , A61K47/18 , A61K47/24 , A61K47/26 , A61K47/32 , A61K47/34 , A61K47/36 , A61K47/38 , A61K47/40 , A61K47/42
CPC分类号： A61K9/0056 , A61K9/2077 , A61K9/2081 , A61K9/2095 , A61K9/501 , A61K9/5015 , A61K9/5026 , A61K9/5042 , A61K9/5047 , A61K9/5078 , A61K31/135
摘要： The present invention relates to an oral pharmaceutical composition in particle form, which comprises particles that contain a drug at the core of the pharmaceutical composition in particle form; a middle layer that contains two types of water-soluble components, an insolubilizer and an insolubilizing substance; and an outer layer for controlling water penetration that contains a water-insoluble substance. The present invention makes it possible to provide a pharmaceutical composition in particle form for oral use with which initial drug release is suppressed, the drug is quickly released thereafter, and lag time can be controlled as needed, and fast-disintegrating tablets containing this composition.
摘要翻译：本发明涉及一种颗粒形式的口服药物组合物，其包含以粒子形式含有药物组合物核心的药物的颗粒; 含有两种水溶性组分的中间层，不溶物和不溶物质; 以及用于控制含水不溶性物质的水渗透的外层。本发明使得可以提供一种用于口服使用的颗粒形式的药物组合物，其中抑制初始药物释放，此后快速释放药物，并且可以根据需要控制滞后时间，以及含有该组合物的快速崩解片剂。

4. 发明申请

US20090239791A1 PHARMACEUTICAL COMPOSITION CONTAINING LIPOPHILIC SUBSTANCE WHICH INHIBITS IL-2 PRODUCTION 审中-公开
标题翻译：含有抑制IL-2生产的脂质物质的药物组合物
公开(公告)号：US20090239791A1
公开(公告)日：2009-09-24
申请号：US12256851
申请日：2008-10-23
申请人： Takayuki Yoshida , Kiyo Nakanishi , Atsushi Maeda , Kazuhiro Sako , Yuki Kasashima , Hiromu Kondo , Tatsunobu Yoshioka , Yuuki Tsutsui
发明人： Takayuki Yoshida , Kiyo Nakanishi , Atsushi Maeda , Kazuhiro Sako , Yuki Kasashima , Hiromu Kondo , Tatsunobu Yoshioka , Yuuki Tsutsui
IPC分类号： A61K38/13 , A61K31/436 , A61K31/343
CPC分类号： A61K9/08 , A61K31/343 , A61K31/365 , A61K31/436 , A61K38/13 , A61K47/10 , A61K47/12 , A61K47/14 , A61K47/44
摘要： A pharmaceutical composition comprising a lipophilic substance which inhibits IL-2 production, and a base capable of inhibiting blood exposure of the substance and delivering the substance to lymph following oral administration, is disclosed. The pharmaceutical composition can inhibit blood exposure of the substance to reduce its adverse effects, and can develop desired pharmacological effects.
摘要翻译：公开了一种药物组合物，其包含抑制IL-2产生的亲脂性物质，以及能够抑制物质的血液暴露并将其输送到口服给药后的淋巴液的碱。药物组合物可以抑制物质的血液暴露以减少其不利影响，并且可以产生所需的药理作用。

5. 发明授权

US09825314B2 Fuel cell and manufacturing method of expanded metal 有权
公开(公告)号：US09825314B2
公开(公告)日：2017-11-21
申请号：US14112394
申请日：2012-04-18
申请人： Atsushi Maeda , Kazumi Sugita , Atsushi Ida , Shingo Morikawa , Keiji Hashimoto , Satoshi Futami
发明人： Atsushi Maeda , Kazumi Sugita , Atsushi Ida , Shingo Morikawa , Keiji Hashimoto , Satoshi Futami
IPC分类号： H01M8/04082 , H01M8/241 , H01M8/2483 , H01M8/0232 , H01M8/0254 , H01M8/0258 , H01M8/04291 , B21D31/04 , H01M8/1007 , H01M8/1018
CPC分类号： H01M8/04201 , B21D31/04 , H01M8/0232 , H01M8/0254 , H01M8/0258 , H01M8/04291 , H01M8/1007 , H01M8/241 , H01M8/2483 , H01M2008/1095 , Y02P70/56 , Y10T29/18
摘要： A cathode-side gas flow path of a cell that forms part of a fuel cell is formed by a first expanded metal arranged on a gas inlet side, and a second expanded metal arranged on a downstream side. The first expanded metal is such that mesh is arranged in a straight line, and gas that flows on a gas diffusion layer side is separated from gas that flows on a separator side. The gas flowrate on the gas inlet side is reduced, so the amount of produced water that is carried away is reduced. As a result, the gas inlet side is inhibited from becoming dry at high temperatures.

6. 发明授权

US08556048B2 Hydraulic shock absorber 有权
标题翻译：液压减震器
公开(公告)号：US08556048B2
公开(公告)日：2013-10-15
申请号：US12068301
申请日：2008-02-05
申请人： Atsushi Maeda , Reiji Nakagawa
发明人： Atsushi Maeda , Reiji Nakagawa
IPC分类号： F16F9/14
CPC分类号： F16F9/092 , B60G17/08 , B60G2202/24
摘要： A piston connected with a piston rod is fitted in a cylinder having a hydraulic fluid sealed therein. A damping force is generated through extension and compression disk valves and an orifice. Vehicle height adjustment is performed with a self-leveling mechanism by transferring the hydraulic fluid between the cylinder and a hydraulic fluid tank. A bladder of the hydraulic fluid tank is clamped between an outer flange portion of a partition member and a casing. Because the hydraulic fluid tank is formed without welding, it is possible to avoid contamination of the hydraulic fluid by welding sputter and thermal deformation. Provision of an O-ring on the outer flange portion can reduce the pressure acting from a reservoir on the clamped portion of the bladder and hence prevent dislodging of the bladder.
摘要翻译：与活塞杆连接的活塞安装在其中密封有液压流体的气缸中。通过延伸和压缩盘阀和孔口产生阻尼力。通过在液压缸和液压油箱之间传递液压流体，通过自动调平机构执行车辆高度调节。液压油箱的气囊夹在分隔件的外凸缘部分和壳体之间。由于液压油箱不经焊接而形成，因此可以通过溅射和热变形来避免液压油的污染。在外部凸缘部分上设置O形环可以降低作用在气囊夹紧部分上的储存器的压力，从而防止气囊的移动。

7. 外观设计

USD674351S1 Circuit breaking terminal for electric vehicle 有权
标题翻译：电动车断路端子
公开(公告)号：USD674351S1
公开(公告)日：2013-01-15
申请号：US29419150
申请日：2012-04-25
申请人： Tomohiro Ikeda , Ryuta Takishita , Kouichirou Mochizuki , Sho Nogashira , Atsushi Maeda
设计人： Tomohiro Ikeda , Ryuta Takishita , Kouichirou Mochizuki , Sho Nogashira , Atsushi Maeda

8. 发明申请

US20120080098A1 Cutting liquid supply device for machine tool 有权
标题翻译：切削机床液体供给装置
公开(公告)号：US20120080098A1
公开(公告)日：2012-04-05
申请号：US13322433
申请日：2010-04-09
申请人： Tadashi Makiyama , Atsushi Maeda , Shinya Takeda , Takuya Kawamoto , Kunihiro Ikeda , Sadaharu Kittaka
发明人： Tadashi Makiyama , Atsushi Maeda , Shinya Takeda , Takuya Kawamoto , Kunihiro Ikeda , Sadaharu Kittaka
IPC分类号： B67D7/72
CPC分类号： B24C1/045 , B23Q11/10 , B23Q11/103 , B23Q11/1046 , Y02P70/169 , Y10T137/2931 , Y10T408/16 , Y10T408/44 , Y10T409/304032
摘要： A cutting liquid supply device in a machine tool is configured to remove gas mixed in a cutting liquid supply line to improve the response of discharging a mist of cutting liquid. Cutting liquid is supplied from a pump (42) through a rotary joint (28) to a mist generation device (24) within a rotating spindle (29). The pressure of the cutting liquid is measured by a pressure sensor (47). An air vent device (30) for opening and closing, with respect to atmospheric pressure, piping (3) that supplies the cutting liquid is provided above the rotary joint (28). A detection signal is inputted in the control board (70) from the pressure sensor (47), and when the control board (70) detects, after the pump (42) stops the supply of the cutting liquid to the piping (3), that the pressure of the cutting liquid does not decrease to a level lower than a predetermined threshold value, the control board (70) instructs the air vent device (30) to open the piping (4) to the atmosphere.
摘要翻译：在机床中的切割液体供给装置被构造成去除混合在切割液体供给管线中的气体，以改善排出切割液体雾的响应。切割液体通过旋转接头（28）从泵（42）供给到旋转主轴（29）内的雾化装置（24）。通过压力传感器（47）测量切割液体的压力。在旋转接头（28）的上方设置有用于打开和关闭相对于大气压力的供给切割液体的配管（3）的排气装置（30）。检测信号从压力传感器（47）输入控制板（70），当控制板（70）检测到泵（42）停止向管路（3）供给切断液后，切割液体的压力不会降低到低于预定阈值的水平，所以控制板（70）指示排气装置（30）将管道（4）打开到大气中。

9. 发明申请

US20100185390A1 NAVIGATION SYSTEM 有权
标题翻译：导航系统
公开(公告)号：US20100185390A1
公开(公告)日：2010-07-22
申请号：US12601732
申请日：2008-03-18
申请人： Yasuhiro Monde , Katsuro Hayami , Masatoshi Fujii , Atsushi Maeda
发明人： Yasuhiro Monde , Katsuro Hayami , Masatoshi Fujii , Atsushi Maeda
IPC分类号： G01C21/26
CPC分类号： G01C21/26 , G01C25/005 , G09B29/102
摘要： A navigation system includes: an angular velocity sensor 1 for detecting a change in an advancement direction of a vehicle; a vehicle azimuth calculation unit 13 for calculating a vehicle azimuth on the basis of angular velocity sensor information obtained from the angular velocity sensor; an on-board camera 2 for shooting a periphery of the vehicle; an image recognition unit 19 for recognizing an image obtained from the on-board camera; and an offset voltage correction unit 21 for performing a drift correction on the angular velocity sensor in accordance with an angle error between the vehicle azimuth calculated by the vehicle azimuth calculation unit and a vehicle azimuth determined from a white line on a road recognized by the image recognition unit.
摘要翻译：导航系统包括：角速度传感器1，用于检测车辆前进方向的变化; 车辆方位角计算单元13，用于基于从角速度传感器获得的角速度传感器信息来计算车辆方位角; 用于拍摄车辆周边的车载照相机2; 用于识别从车载摄像机获得的图像的图像识别单元19; 以及偏移电压校正单元21，用于根据由车辆方位计算单元计算的车辆方位角与由图像识别的道路上的白线确定的车辆方位角之间的角度误差，对角速度传感器进行漂移校正识别单位。

10. 发明申请

US20060191736A1 Electric power steering device 审中-公开
标题翻译：电动助力转向装置
公开(公告)号：US20060191736A1
公开(公告)日：2006-08-31
申请号：US10550316
申请日：2004-04-16
申请人： Atsushi Maeda , Kazuo Chikaraishi
发明人： Atsushi Maeda , Kazuo Chikaraishi
IPC分类号： B62D5/04
CPC分类号： B62D5/0409 , F16H1/16 , F16H55/24 , F16H2057/0213
摘要： A subject of the present invention is to provide an electric power steering capable of improving a contact ratio by using an hourglass worm to attain a higher output, and also performing a correction of a misalignment easily by simplifying remarkably a fitting operation of the hourglass worm. A worm gear system causes a hourglass worm 2 driven by an electric motor 4 to mesh with a worm wheel 3 provided to an output shaft 5, and a bearing 7 on the shaft end side, which bears rotatably the hourglass worm 2 is composed of a tapered roller bearing an outer ring of which can be separated. In a fitting operation, an inner ring 7a and rolling elements 7b are fitted into the hourglass worm 2 and also an outer ring 7c is fitted in advance in a gear housing 1. Then, the tapered roller bearing 7 is assembled in the gear housing 1 by moving the hourglass worm 2 obliquely to a rotating shaft line of the hourglass worm 2 in the gear housing 1 along a raceway of the outer ring 7c.
摘要翻译：本发明的目的是提供一种能够通过使用沙漏蜗杆来提高接触比以获得更高输出的电动助力转向器，并且通过简单地简化沙漏蜗杆的装配操作，容易地进行未对准的校正。蜗轮系统使得由电动机4驱动的沙漏蜗杆2与设置在输出轴5上的蜗轮3啮合，并且轴端侧的可旋转地安装有沙漏蜗杆2的轴承7由圆锥滚子轴承外圈可分离。在装配操作中，将内圈7a和滚动元件7b装配到沙漏蜗杆2中，并且外圈7c预先安装在齿轮箱1中。然后，通过沿着外圈7c的滚道将沙漏蜗杆2倾斜地旋转到齿轮箱1中的沙漏蜗杆2的旋转轴线，将锥形滚子轴承7组装在齿轮箱1中。

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