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    • 1. 发明授权
    • Implantable valvular prosthesis
    • 可植入瓣膜假体
    • US07347869B2
    • 2008-03-25
    • US10699295
    • 2003-10-31
    • Hikmat HojeibaneDavid Christopher Majercak
    • Hikmat HojeibaneDavid Christopher Majercak
    • A61F2/06
    • A61F2/2418A61F2/2475A61F2002/068A61F2220/0016A61F2230/0054
    • The present invention relates to a medical device, and in particular, to a stent-based valve. The valve includes a radially expandable structural frame including an anchor structure having a first and a second open end, a connecting member having a first and a second end, and a cantilever valve strut having a first and a second end. The first end of the connecting member is attached to the second end of the anchor structure. The first end of the cantilever valve strut is cooperatively associated with the second end of the connecting member. The prosthetic valve further includes a biocompatible membrane assembly having a substantially tubular configuration about the longitudinal axis, with a first open and a second closed end. The first end of the membrane assembly is attached to the structural frame along the second end of the cantilever valve strut.
    • 本发明涉及一种医疗装置,特别涉及一种基于支架的阀。 该阀包括具有第一和第二开口端的锚定结构的可径向扩张的结构框架,具有第一和第二端的连接构件以及具有第一和第二端的悬臂阀支柱。 连接构件的第一端附接到锚结构的第二端。 悬臂阀支柱的第一端与连接构件的第二端协作关联。 假体瓣膜还包括生物相容性膜组件,其具有围绕纵向轴线的基本上管状的构造,具有第一开放和第二闭合端。 膜组件的第一端沿着悬臂阀支柱的第二端连接到结构框架上。
    • 2. 发明授权
    • Implantable valvular prosthesis
    • 可植入瓣膜假体
    • US07070616B2
    • 2006-07-04
    • US10699014
    • 2003-10-31
    • David Christopher MajercakHikmat Hojeibane
    • David Christopher MajercakHikmat Hojeibane
    • A61F2/06
    • A61F2/2475A61F2/2418A61F2220/0016A61F2230/0054
    • The present invention relates to a medical device, and in particular, to a stent-based valve. The valve includes a radially expandable structural frame including an anchor structure having a first and a second open end, a connecting member having a first and a second end, and a cantilever valve strut having a first and a second end. The first end of the connecting member is attached to the second end of the anchor structure. The first end of the cantilever valve strut is cooperatively associated with the second end of the connecting member. The prosthetic valve further includes a biocompatible membrane assembly having a substantially tubular configuration disposed longitudinally about at least a portion of the connecting member. The membrane assembly has a first end having a first diameter and a second end having a second diameter, wherein the first diameter is greater than the second diameter. The first end of the membrane assembly is attached along the second end of the cantilever valve strut.
    • 本发明涉及一种医疗装置,特别涉及一种基于支架的阀。 该阀包括具有第一和第二开口端的锚定结构的可径向扩张的结构框架,具有第一和第二端的连接构件以及具有第一和第二端的悬臂阀支柱。 连接构件的第一端附接到锚结构的第二端。 悬臂阀支柱的第一端与连接构件的第二端协作关联。 假体瓣膜还包括生物相容性膜组件,其具有围绕连接构件的至少一部分纵向设置的大致管状结构。 膜组件具有第一端和第二端,第一端具有第一直径,第二端具有第二直径,其中第一直径大于第二直径。 膜组件的第一端沿悬臂阀支柱的第二端连接。
    • 4. 发明授权
    • Frame based unidirectional flow prosthetic implant
    • 基于框架的单向流动假体植入物
    • US07351256B2
    • 2008-04-01
    • US10402180
    • 2003-03-28
    • Hikmat HojeibaneDavid Christopher Majercak
    • Hikmat HojeibaneDavid Christopher Majercak
    • A61F2/06A61F2/24
    • A61F2/2475A61F2/2418A61F2002/825A61F2210/0076A61F2230/0054
    • The present invention relates to a medical device, and in particular, to a stent-based valve. The valve includes a radially expandable structural frame comprising a proximal anchor and a distal anchor. The proximal and distal anchors are formed from a lattice of interconnected elements, and have a substantially cylindrical configuration with first and second open ends and a longitudinal axis extending there between. The stent based valve also comprises one or more connecting members, each having a first and a second end. The first end of each connecting member is attached to the proximal anchor and the second end of each connecting member is attached to the distal anchor. A biocompatible valve assembly is attached to the proximal anchor and extends distally along the one or more connecting members.
    • 本发明涉及一种医疗装置,特别涉及一种基于支架的阀。 该阀包括可径向扩张的结构框架,其包括近端锚固件和远端锚固件。 近端和远端锚固件由互连元件的格子形成,并且具有基本上圆柱形的构造,其具有第一和第二开口端以及在其之间延伸的纵向轴线。 基于支架的阀还包括一个或多个连接构件,每个具有第一端和第二端。 每个连接构件的第一端附接到近端锚固件,并且每个连接构件的第二端附接到远端锚固件。 生物相容性阀组件附接到近端锚固件并且沿着一个或多个连接构件向远侧延伸。
    • 8. 发明授权
    • Method of forming a tubular membrane on a structural frame
    • 在结构框架上形成管状膜的方法
    • US07270675B2
    • 2007-09-18
    • US10402048
    • 2003-03-28
    • Iksoo ChunMark B. RollerDavid Christopher Majercak
    • Iksoo ChunMark B. RollerDavid Christopher Majercak
    • A61F2/06
    • D04H3/07A61F2/2412A61F2/2415A61F2/2418A61F2/2475A61F2/915A61F2002/825A61F2002/91533A61F2002/91558A61F2002/91575A61F2002/91583A61F2220/0058A61F2230/0054A61L27/18A61L27/34A61L27/54A61L2300/00D01D5/0084D01F6/32D01F6/84C08L67/04
    • The present invention relates to a medical device and method of forming the medical device. In particular, the present invention relates to a medical device having a tubular membrane structure over a radially expandable structural frame, and to a method of forming the tubular membrane on the radially expandable structural frame. In one aspect, a structural frame is placed over a spinning mandrel and a fiber is electro-statically spun over at least a portion of the structural frame forming a membrane. A transfer sheath may be used between the mandrel and structural frame to prevent the electro-statically spun fiber from adhering to the mandrel. In another aspect, a first membrane is spun over the mandrel before the structural frame is placed over the mandrel. In this aspect, at least a portion of the structural frame is sandwiched between the membranes. The membrane or membranes and structural frame form a fiber spun frame assembly. The fiber spun frame assembly may be coated with an elastic polymer. In addition, the membrane or membranes may go through some post processing to achieve desired characteristics or configurations.
    • 本发明涉及形成医疗装置的医疗装置及其方法。 特别地,本发明涉及一种在可径向扩张的结构框架上具有管状膜结构的医疗装置以及在径向可扩张的结构框架上形成管状膜的方法。 在一个方面,将结构框架放置在纺丝心轴上,并且将纤维在形成膜的结构框架的至少一部分上静电纺丝。 可以在心轴和结构框架之间使用转移护套,以防止静电纺丝纤维粘附到心轴上。 在另一方面,在结构框架放置在心轴上之前,将第一膜旋转在心轴上。 在这方面,结构框架的至少一部分被夹在膜之间。 膜或膜和结构框架形成纤维纺纱架组件。 纤维纺丝框架组件可以涂覆有弹性聚合物。 此外,膜或膜可以经历一些后处理以实现期望的特性或构型。
    • 10. 发明授权
    • Method of placing a tubular membrane on a structural frame
    • 将管状膜放置在结构框架上的方法
    • US07485141B2
    • 2009-02-03
    • US10401453
    • 2003-03-28
    • David Christopher MajercakVipul Bhupendra DaveIksoo ChunMark B. Roller
    • David Christopher MajercakVipul Bhupendra DaveIksoo ChunMark B. Roller
    • A61F2/06
    • A61F2/2475A61F2/2412A61F2/2418A61F2002/825A61F2230/0054
    • The present invention relates to a medical device, and more particularly to a method of forming a tubular membrane on a radially expandable structural frame. In one aspect, a structural frame is placed over a spinning mandrel and a fiber is electro-statically spun over at least a portion of the structural frame forming a membrane. A transfer sheath may be used between the mandrel and structural frame to prevent the electrostatically spun fiber from adhering to the mandrel. In another aspect, a first membrane is spun over the mandrel before the structural frame is placed over the mandrel. In this aspect, at least a portion of the structural frame is sandwiched between the membranes. The membrane or membranes and structural frame form a fiber spun frame assembly. The fiber spun frame assembly may be coated with an elastic polymer. In addition, the membrane or membranes may go through some post processing to achieve desired characteristics or configurations.
    • 医疗装置技术领域本发明涉及一种医疗装置,更具体地说,涉及一种在径向可展开的结构框架上形成管状膜的方法。 在一个方面,将结构框架放置在纺丝心轴上,并且将纤维在形成膜的结构框架的至少一部分上静电纺丝。 可以在心轴和结构框架之间使用转移护套,以防止静电纺丝纤维粘附到心轴上。 在另一方面,在结构框架放置在心轴上之前,将第一膜旋转在心轴上。 在这方面,结构框架的至少一部分被夹在膜之间。 膜或膜和结构框架形成纤维纺纱架组件。 纤维纺丝框架组件可以涂覆有弹性聚合物。 此外,膜或膜可以经历一些后处理以实现期望的特性或构型。