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1. 发明授权

US07390460B2 Control device for automatic liquid handling system 失效
标题翻译：自动液体处理系统控制装置
公开(公告)号：US07390460B2
公开(公告)日：2008-06-24
申请号：US10714891
申请日：2003-11-18
申请人： Hidetaka Osawa , Hiroatsu Toi , Kenji Yamada , Tadashi Ohkawara
发明人： Hidetaka Osawa , Hiroatsu Toi , Kenji Yamada , Tadashi Ohkawara
IPC分类号： G01N21/00
CPC分类号： G01N35/0092 , Y10T436/2575
摘要： In reagent reaction experiments using microplates, a desired period of time can be set for determining the time to introduce a reaction stop solution after introduction of a reagent. The set time is measured starting from the introduction of the reagent and the reaction stop solution is introduced immediately after expiration of the set time. A control device for an automatic liquid handling system having the above-described reaction time managing feature is also provided with a self-diagnosing function that is capable of determining whether scheduled processes are executable or not during the time set before execution of the processes and informing an operator of the results of determination.
摘要翻译：在使用微孔板的试剂反应实验中，可以设定期望的时间段以确定引入试剂后引入反应停止溶液的时间。从引入试剂开始测定凝固时间，并在设定时间期满后立即引入反应停止溶液。具有上述反应时间管理特征的自动液体处理系统的控制装置还具有能够在执行处理之前设定的时间内确定调度过程是否可执行的自诊断功能，并通知操作人员确定结果。

2. 发明授权

US07374720B2 Control device for automatic liquid handling system 失效
标题翻译：自动液体处理系统控制装置
公开(公告)号：US07374720B2
公开(公告)日：2008-05-20
申请号：US10714889
申请日：2003-11-18
申请人： Hiroatsu Toi , Hidetaka Osawa , Kenji Yamada , Tadashi Ohkawara
发明人： Hiroatsu Toi , Hidetaka Osawa , Kenji Yamada , Tadashi Ohkawara
IPC分类号： B32B5/02
CPC分类号： G01N35/1011 , G01N2035/103 , Y10T436/2575
摘要： In reagent reaction experiments using microplates, the operator cannot just set dispensing tips in all the fixing holes of the dispensing tip container. It is necessary to carry out the time-consuming task of deciding in advance on a suitable arrangement of positions for the dispensing tips. It is also necessary for the operator to carry out the time-consuming task of determining in advance the quantity of reagent used and how the reagent is to be arranged. These problems are solved by providing a control device that includes a dispensing tip arrangement calculator and reagent quantity and arrangement calculator, and that can inform the operator of these results. The dispensing tip arrangement, the reagent quantity used, and the reagent arrangement is calculated from the information set in advance on specific reagent, the quantity of reagent dispensed into one well of the microplate, the range of wells in the microplate into which reagent is dispensed, and the direction of dispensing.
摘要翻译：在使用微孔板的试剂反应实验中，操作者不能仅在分配尖端容器的所有固定孔中设置分配尖端。需要进行耗时的任务，即预先决定用于分配提示的适当位置。操作者还需要预先确定所用试剂的数量以及如何布置试剂的耗时的任务。这些问题通过提供一种控制装置来解决，所述控制装置包括分配尖端布置计算器和试剂数量和布置计算器，并且可以向操作者通知这些结果。根据预先对特定试剂设定的信息，分配到微板的一个孔中的试剂的量，分配试剂的微板中的孔的范围计算分配尖端装置，使用的试剂量和试剂装置，以及分配方向。

3. 发明授权

US07618589B2 Automatic dispenser 失效
标题翻译：自动分配器
公开(公告)号：US07618589B2
公开(公告)日：2009-11-17
申请号：US11116299
申请日：2005-04-28
申请人： Hiroatsu Toi , Kenji Yamada , Masataka Morita , Hidetaka Osawa , Tadashi Ohkawara
发明人： Hiroatsu Toi , Kenji Yamada , Masataka Morita , Hidetaka Osawa , Tadashi Ohkawara
IPC分类号： B01L3/02
CPC分类号： G01N35/1011 , G01N35/1065 , G01N2035/1013 , G01N2035/103
摘要： An automatic dispenser includes a dispensing head, a transporter, a controller, sensors, and an adjustor. The dispensing head accommodates a plurality of dispensing tips and draws liquid into and ejects liquid from the dispensing tips. The transporter moves the dispensing head within an XYZ space. The controller controls drawing and ejecting of liquid by the dispensing head and movement of the dispensing head by the transporter. The sensors detect whether dispensing tips are mounted in the dispensing head. The adjustor aligns the reference positions of the dispensing head and the sensors in the XY plane.
摘要翻译：自动分配器包括分配头，输送器，控制器，传感器和调节器。分配头容纳多个分配尖端并将液体从分配尖端抽出并喷出液体。输送器将分配头移动到XYZ空间内。控制器通过分配头控制液体的抽出和排出，并通过运送器移动分配头。传感器检测分配尖端是否安装在分配头中。调节器将分配头和传感器的参考位置对准XY平面。

4. 发明申请

US20060051246A1 Automatic dispenser 失效
公开(公告)号：US20060051246A1
公开(公告)日：2006-03-09
申请号：US11116299
申请日：2005-04-28
申请人： Hiroatsu Toi , Kenji Yamada , Masataka Morita , Hidetaka Osawa , Tadashi Ohkawara
发明人： Hiroatsu Toi , Kenji Yamada , Masataka Morita , Hidetaka Osawa , Tadashi Ohkawara
IPC分类号： B01L3/02
CPC分类号： G01N35/1011 , G01N35/1065 , G01N2035/1013 , G01N2035/103
摘要： An automatic dispenser includes a dispensing head, a transporter, a controller, sensors, and an adjustor. The dispensing head accommodates a plurality of dispensing tips and draws liquid into and ejects liquid from the dispensing tips. The transporter moves the dispensing head within an XYZ space. The controller controls drawing and ejecting of liquid by the dispensing head and movement of the dispensing head by the transporter. The sensors detect whether dispensing tips are mounted in the dispensing head. The adjustor aligns the reference positions of the dispensing head and the sensors in the XY plane.

5. 发明授权

US07101511B2 Microplate liquid handling system 有权
标题翻译：微孔板液体处理系统
公开(公告)号：US07101511B2
公开(公告)日：2006-09-05
申请号：US10669796
申请日：2003-09-25
申请人： Hiroatsu Toi , Kenji Yamada , Tadashi Ohkawara , Masashi Nagaoka
发明人： Hiroatsu Toi , Kenji Yamada , Tadashi Ohkawara , Masashi Nagaoka
IPC分类号： B01L3/02
CPC分类号： G01N35/1074 , G01N35/028 , G01N35/109 , G01N2035/1076
摘要： A microplate liquid handling system capable of automatically performing both longitudinal collective suction/discharge and lateral collective suction/discharge on a single microplate. The microplate liquid handling system has a main body equipped with a moving device, a rotating mechanism, a dispensing mechanism, and a stage. Connected to the moving device is the dispensing mechanism for performing dispensing on wells in a microplate on the stage through the rotating mechanism. A plurality of cylinders are arranged in a row in the dispensing mechanism. The dispensing mechanism is capable of moving forwards and backwards and to the right and left with respect to the main body, and is rotatable about a vertically directed rotation axis, making it possible to change the direction of the cylinder array from origin position to 90 degrees position and vice versa.
摘要翻译：一种微孔板液体处理系统，能够在单个微孔板上自动执行纵向共同吸入/排出和侧向共同吸入/排出。微板液体处理系统具有配备有移动装置，旋转机构，分配机构和台架的主体。连接到移动装置的是分配机构，用于通过旋转机构在台上的微板中进行分配。多个气缸在分配机构中排成一列。分配机构能够相对于主体向前和向后以及向左右移动，并且可以围绕垂直定向的旋转轴线旋转，使得可以将气缸阵列的方向从原点位置改变到90度位置，反之亦然。

6. 发明授权

US07169362B2 Microplate liquid handling system 失效
标题翻译：微孔板液体处理系统
公开(公告)号：US07169362B2
公开(公告)日：2007-01-30
申请号：US10669810
申请日：2003-09-25
申请人： Hiroatsu Toi , Kenji Yamada , Tadashi Ohkawara , Masashi Nagaoka
发明人： Hiroatsu Toi , Kenji Yamada , Tadashi Ohkawara , Masashi Nagaoka
IPC分类号： B01L3/02
CPC分类号： G01N35/1067 , G01N35/1072 , G01N35/1074 , G01N35/109 , G01N2035/103
摘要： A microplate liquid handling system requiring minimum installation area, helping to avoid waste of various reagents, and making it possible to perform dispensing the various reagents in the shortest possible time. The microplate liquid handling system has a main frame body provided with a moving mechanism, a dispensing mechanism, and a stage. On the stage, a microplate, two dispensing tip containers, and two reagent vessels are mounted. Formed in the microplate are 12×8 wells, i.e., 96 wells in total, arranged in matrix. The microplate, the dispensing tip containers, and the reagent vessels are substantially of the same, rectangular configuration. Each of the two dispensing tip containers is capable of accommodating 12×8 dispensing tips in total in a matrix fashion.
摘要翻译：需要最小安装面积的微孔板液体处理系统，有助于避免各种试剂的浪费，并且可以在尽可能短的时间内进行各种试剂的分配。微孔板液体处理系统具有设置有移动机构，分配机构和台架的主框体。在舞台上安装微板，两个分配头容器和两个试剂容器。在微量培养板中形成的是12×8个孔，即96个孔，总共排列成矩阵。微板，分配尖端容器和试剂容器基本上相同，矩形构造。两个分配尖端容器中的每一个能够以矩阵方式总共容纳12×8个分配尖端。

7. 发明授权

US07643236B2 Centrifugal machine 失效
标题翻译：离心机
公开(公告)号：US07643236B2
公开(公告)日：2010-01-05
申请号：US11848400
申请日：2007-08-31
申请人： Tadashi Ohkawara
发明人： Tadashi Ohkawara
IPC分类号： G11B5/02
CPC分类号： B04B15/02 , B04B13/00
摘要： A centrifugal machine comprises a rotor drivable and rotatable by a motor while holding a specimen, and including a recording medium for recording data therein; a Peltier element, when a voltage is applied thereto, for controlling the temperature of the rotor; a recording head disposed at a position adjacent to the rotor for reproducing data from the recording medium or for recording data into the recording medium; and, a control device not only for controlling the operation of the Peltier element when the Peltier element controls the temperature of the rotor but also for controlling the operation of the recording head when the recording head reproduces the data from the recording medium or records the data into the recording medium, wherein the control device, when carrying out the data reproduction or data recording with respect to the recording medium provided in the rotor, controls the Peltier element in such a manner that the operation of the Peltier element is caused to stop.
摘要翻译：一种离心机，其特征在于，包括在保持试样的状态下由马达驱动并可旋转的转子，并且包括用于在其中记录数据的记录介质; 当对其施加电压时，珀尔帖元件用于控制转子的温度; 记录头，设置在与转子相邻的位置处，用于从记录介质再现数据或将数据记录到记录介质中; 以及控制装置，其不仅用于当珀耳帖元件控制转子的温度时控制珀尔帖元件的操作，而且还用于当记录头从记录介质再现数据或记录数据时控制记录头的操作其中控制装置在对设置在转子中的记录介质进行数据再现或数据记录时，以使得停止Peltier元件的操作的方式控制珀尔帖元件。

8. 发明授权

US06338708B1 Centrifuge with a suspension for locating the drive in an axial direction 有权
标题翻译：离心机带有用于沿轴向定位驱动器的悬架
公开(公告)号：US06338708B1
公开(公告)日：2002-01-15
申请号：US09613907
申请日：2000-07-11
申请人： Masahiro Miura , Tadashi Ohkawara , Shinki Ohtsu
发明人： Masahiro Miura , Tadashi Ohkawara , Shinki Ohtsu
IPC分类号： B04B914
CPC分类号： B04B9/12 , Y10T74/2131
摘要： A centrifuge includes a rotor and a drive device for rotating the rotor. A support frame is located between the rotor and the drive device. A viscoelastic member is provided between the support frame and the drive device. A locating device operates for locating the drive device in an axial direction. The locating device may include a suspension connecting the support frame and a bottom of the drive device. Preferably, the suspension includes one of a wire rope and a piano wire.
摘要翻译：离心机包括转子和用于旋转转子的驱动装置。支撑架位于转子和驱动装置之间。在支撑框架和驱动装置之间设置粘弹性构件。定位装置用于沿轴向定位驱动装置。定位装置可以包括连接支撑框架和驱动装置的底部的悬架。优选地，悬架包括钢丝绳和钢琴线之一。

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