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1. 发明授权

US06432439B1 O/W emulsion composition 失效
标题翻译： O / W乳液组合物
公开(公告)号：US06432439B1
公开(公告)日：2002-08-13
申请号：US09541682
申请日：2000-04-03
申请人： Hidekazu Suzuki , Satoshi Yamazaki , Yoshikazu Naito , Masanobu Takeuchi , Yoshiaki Saito
发明人： Hidekazu Suzuki , Satoshi Yamazaki , Yoshikazu Naito , Masanobu Takeuchi , Yoshiaki Saito
IPC分类号： A61K3156
CPC分类号： A61K9/0048 , A61K9/107 , Y10S514/912 , Y10S514/914 , Y10S514/938 , Y10S514/939 , Y10S514/943
摘要： An O/W emulsion composition comprising fluorometholone or clobetasone butyrate, a phospholipid, an oil, a nonionic water-soluble cellulose derivative, and water. The O/W composition has advantages that fluorometholone or clobetasone butyrate contained therein is highly bioavailable and that the solubility of fluorometholone or clobetasone butyrate and the concentration thereof present in the composition can be kept stable. Thus, this composition is usable for the treatment of various inflammatory diseases by the generalized or local administration thereof. It provides a drug which shows an anti-inflammatory activity equal or higher than that of commercially available eye drops comprising a suspension of such an active ingredient even when it is applied in a smaller dose than that of commercially available one and further provides a drug having excellent storability, which reduces apprehension of systemic side effects of fluorometholone or clobetasone butyrate when it is applied to the eyes.
摘要翻译：包含氟美托隆或丁酸氯倍他松，磷脂，油，非离子水溶性纤维素衍生物和水的O / W乳液组合物。 O / W组合物的优点在于其中所含的氟米龙或丁酸氯倍他松具有高度的生物利用度，并且可以保持氟代米尔龙或丁酸氯倍他松的溶解度及其在组合物中的浓度。因此，该组合物可用于通过其广泛或局部施用治疗各种炎性疾病。它提供了一种药物，其显示的抗炎活性等于或高于包含这种活性成分的悬浮液的市售眼药水的抗炎活性，即使其施用量小于可商购的滴眼剂，并且还提供具有优异的保存性，减少了当应用于眼睛时，氟米龙或丁酸氯倍他松的全身副作用的忧虑。

2. 发明授权

US5693337A Stable lipid emulsion 失效
标题翻译：稳定的脂质乳剂
公开(公告)号：US5693337A
公开(公告)日：1997-12-02
申请号：US500087
申请日：1995-07-10
申请人： Hidekazu Suzuki , Satoshi Yamazaki , Yoshikazu Naito , Kenji Endo , Touru Oguma , Makoto Maeda
发明人： Hidekazu Suzuki , Satoshi Yamazaki , Yoshikazu Naito , Kenji Endo , Touru Oguma , Makoto Maeda
IPC分类号： A61K9/00 , A61K9/107 , A61K47/18 , A61K9/127
CPC分类号： A61K9/0029 , A61K47/183 , A61K9/0014 , A61K9/0019 , A61K9/0048 , A61K9/1075 , Y10S514/937 , Y10S514/943
摘要： A lipid emulsion which comprises (A) an oil component, (B) an emulsifying agent containing yolk lecithin and/or soybean lecithin, and (C) water, wherein the lipid emulsion further comprises citric acid or a pharmaceutically acceptable salt thereof and at least one member selected from the group consisting of methionine, phenylalanine, serine, histidine and pharmaceutically acceptable salts thereof, provided that it does not simultaneously contain methionine and phenylalanine. The addition of citric acid and histidine, methionine, phenylalanine and/or serine to a lipid emulsion containing natural lecithin as an emulsifying agent permits the prevention of change of color and formation of oil drops associated with the conventional natural lecithin-containing lipid emulsion due to the synergistic effect of the foregoing additives. The drug-containing lipid emulsion is also excellent in storage stability and thus the foregoing lipid emulsion can be applied to drugs such as injections, eye drops, nasal drops, lotions or liniments, inhalants and drugs for oral administration or cosmetics such as humectants.
摘要翻译：一种脂质乳剂，其包含（A）油组分，（B）含有卵黄卵磷脂和/或大豆卵磷脂的乳化剂和（C）水，其中所述脂质乳液还包含柠檬酸或其药学上可接受的盐，至少选自甲硫氨酸，苯丙氨酸，丝氨酸，组氨酸及其药学上可接受的盐中的一种，条件是其不同时含有甲硫氨酸和苯丙氨酸。将柠檬酸和组氨酸，甲硫氨酸，苯丙氨酸和/或丝氨酸加入到含有天然卵磷脂作为乳化剂的脂质乳剂中，可以防止与常规含天然卵磷脂的脂质乳液相关的颜色变化和油滴的形成，这是由于上述添加剂的协同效应。含药物的脂质乳剂的储存稳定性也优异，因此上述脂质乳剂可以用于药物如注射剂，滴眼剂，滴鼻剂，洗剂或搽剂，用于口服给药的吸入剂和药物，或诸如保湿剂的化妆品。

3. 发明授权

US6132751A O/W emulsion composition for eye drops 失效
标题翻译：用于滴眼剂的O / W乳液组合物
公开(公告)号：US6132751A
公开(公告)日：2000-10-17
申请号：US150
申请日：1998-02-03
申请人： Hidekazu Suzuki , Satoshi Yamazaki , Yoshikazu Naito , Takahiro Wada , Kaei Nagoshi , Noriko Tahira , Reiko Hirata , Touru Oguma , Makoto Maeda
发明人： Hidekazu Suzuki , Satoshi Yamazaki , Yoshikazu Naito , Takahiro Wada , Kaei Nagoshi , Noriko Tahira , Reiko Hirata , Touru Oguma , Makoto Maeda
IPC分类号： A61K9/00 , A61F2/00 , A61F13/00
CPC分类号： A61K31/573 , A61K9/0048
摘要： An O/W emulsion composition for eye drops comprises a drug selected from the group consisting of fluorometholone, clobetasone butyrate and clobetasol propionate; a phospholipid; liquid paraffine; and water. The O/W emulsion composition is excellent in solubility of fluorometholone, clobetasone butyrate and clobetasol propionate in the tear fluid. Therefore, the composition would exhibit an anti-inflammatory activity identical to or superior to those achieved by the conventional pharmaceutical preparations, by the administration thereof at a dose lower than those for these known drugs. The composition would also be excellent from the economical standpoint and permit reduction of systemic side effects which would be encountered when the conventional drugs are instilled in the eyes.
摘要翻译： PCT No.PCT / JP96 / 02187 Sec。 371日期1998年2月3日 102（e）1998年2月3日PCT PCT 1996年8月5日PCT公布。公开号WO97 / 05882 日期：1997年2月20日用于眼药水的O / W乳液组合物包含选自氟米隆，丁酸氯倍他丁和丙酸氯倍他索的药物; 磷脂; 液体石蜡; 和水。 O / W乳液组合物在泪液中的氟米龙，丁酸氯倍他丁和丙酸氯倍他索的溶解度优异。因此，通过以比这些已知药物低的剂量给药，组合物将表现出与常规药物制剂相同或优于常规药物制剂的抗炎活性。从经济角度看，组合物也是优异的，并且允许减少常规药物滴入眼睛时会遇到的全身副作用。

4. 发明授权

US09456980B2 Latanoprost-containing aqueous pharmaceutical composition 有权
标题翻译：含拉坦前列素的水性药物组合物
公开(公告)号：US09456980B2
公开(公告)日：2016-10-04
申请号：US12674962
申请日：2008-08-29
申请人： Kohei Yoda , Satoshi Yamazaki , Emi Kawaguchi
发明人： Kohei Yoda , Satoshi Yamazaki , Emi Kawaguchi
IPC分类号： A61K9/00 , A61K31/5575 , A61K31/215 , A61K31/557 , A61K47/14 , A61K47/26 , A61K47/44
CPC分类号： A61K9/0048 , A61K31/215 , A61K31/557 , A61K31/5575 , A61K47/14 , A61K47/26 , A61K47/44
摘要： The invention provides a latanoprost-containing aqueous pharmaceutical composition filled in a filter-equipped container, with the adsorption of latanoprost by the filter being prevented. In the latanoprost-containing aqueous pharmaceutical composition filled in the filter-equipped container, a nonionic surfactant is contained in the composition and the filter is made from at least one material selected from the group consisting of polyether sulfone, polyvinylidene fluoride, polycarbonate, and polytetrafluoroethylene.
摘要翻译：本发明提供一种填充在装有过滤器的容器中的含有拉坦前列素的水性药物组合物，其中通过过滤器吸收拉坦前列素。在装有过滤器的容器中的含有拉坦前列素的水性药物组合物中，组合物中含有非离子表面活性剂，过滤器由选自聚醚砜，聚偏二氟乙烯，聚碳酸酯，聚四氟乙烯。

5. 发明授权

US08749831B2 Printing system and data transfer method 有权
标题翻译：打印系统和数据传输方式
公开(公告)号：US08749831B2
公开(公告)日：2014-06-10
申请号：US13647808
申请日：2012-10-09
申请人： Satoshi Yamazaki , Shinichi Arazaki , Kohei Utsunomiya
发明人： Satoshi Yamazaki , Shinichi Arazaki , Kohei Utsunomiya
IPC分类号： G06F3/12
CPC分类号： H04N1/33323 , G06F3/1212 , G06F3/1236 , G06F3/1244 , G06F3/1285 , G06F3/1292 , H04N1/00233 , H04N1/33361 , H04N2201/0044 , H04N2201/0082 , H04N2201/33357 , H04N2201/33378
摘要： A printing system provided with a printer and a host computer which transfers image data to the printer includes a data transfer unit configured to transfer the image data as image data of a first data format in the case where a connection between the printer and the host computer is first connection means, and transfer the image data as image data of a second data format in the case where a connection between the printer and the host computer is second connection means, wherein the second connection means has less data communication amount per unit time than the first connection means, and when given image data is transferred, image data of the second data format, corresponding to the given image data, has less data amount than image data of the first data format, corresponding to the given image data.
摘要翻译：具有将图像数据传送到打印机的打印机和主计算机的打印系统包括数据传送单元，其被配置为在打印机和主计算机之间的连接的情况下将图像数据作为第一数据格式的图像数据传送是第一连接装置，并且在打印机和主机之间的连接是第二连接装置的情况下，将图像数据作为第二数据格式的图像数据传送，其中第二连接装置具有比每单位时间少的数据通信量第一连接装置，并且当传送给定图像数据时，对应于给定图像数据的第二数据格式的图像数据具有比对应于给定图像数据的第一数据格式的图像数据更少的数据量。

6. 发明授权

US08039423B2 Lubricant composition, speed reduction gear using the lubricant composition, and electric power steering apparatus using the speed reduction gear 有权
标题翻译：使用润滑剂组合物的润滑剂组合物，减速装置以及使用减速装置的电动助力转向装置
公开(公告)号：US08039423B2
公开(公告)日：2011-10-18
申请号：US10593820
申请日：2005-03-23
申请人： Kouji Kitahata , Fumiaki Kasahara , Yoshimasa Shirai , Takashi Okaniwa , Satoshi Yamazaki
发明人： Kouji Kitahata , Fumiaki Kasahara , Yoshimasa Shirai , Takashi Okaniwa , Satoshi Yamazaki
IPC分类号： C10M135/10 , C10M149/00
CPC分类号： C10M169/06 , C10M2201/05 , C10M2201/0626 , C10M2201/0876 , C10M2205/0206 , C10M2207/1265 , C10M2215/1026 , C10M2217/045 , C10M2219/0445 , C10M2219/0466 , C10N2220/022 , C10N2220/08 , C10N2220/082 , C10N2230/06 , C10N2230/76 , C10N2240/04 , C10N2250/10 , F16H1/16 , F16H57/0006 , F16H57/0498 , Y10T74/19991
摘要： Disclosed are a lubricant composition including a lubricating base oil, fine particles and a calcium sulfonate-based thickener, a speed reduction gear filled with the lubricant composition, and an electric power steering apparatus including the speed reduction gear. The invention reduces operating noise of the speed reduction gear, regardless of the amount of backlash that occurs on combining a small gear and a large gear and without a more complicated structure for the speed reduction gear, by action of the fine particles. Further, separation of oil is prevented, by action of the calcium sulfonate-based thickener of the lubricant composition, so that electric power steering apparatus noise within the inside of a car is reduced at a low cost.
摘要翻译：公开了一种润滑剂组合物，其包含润滑基础油，细颗粒和基于磺酸钙的增稠剂，填充有润滑剂组合物的减速齿轮以及包括减速齿轮的电动助力转向装置。无论细小颗粒的作用如何，通过组合小齿轮和大齿轮以及减速齿轮结构不复杂的结构，都能够减轻减速装置的运转噪音。此外，通过润滑剂组合物的磺酸钙系增稠剂的作用，可以防止油分离，从而以低成本降低了汽车内部的电动助力转向装置的噪音。

7. 发明授权

US07835085B2 Lens barrel and method of operation of lens barrel 有权
标题翻译：镜筒和镜筒操作方法
公开(公告)号：US07835085B2
公开(公告)日：2010-11-16
申请号：US11588275
申请日：2006-10-27
申请人： Satoshi Yamazaki
发明人： Satoshi Yamazaki
IPC分类号： G02B15/14
CPC分类号： G02B7/10 , G02B15/14
摘要： A lens barrel having a first moving barrel, second moving barrel, and a third moving barrel. The first moving barrel has first cam grooves configured corresponding to a focusing operation and holds an optical system used in a focusing operation. The second moving barrel has second cam grooves and is provided in relation to the first moving barrel. The third moving barrel has third cam grooves configured corresponding to a zoom operation and can move relative to a fixed barrel. The second cam grooves correct a position of said optical system corresponding to a drive operation of the third cam grooves.
摘要翻译：镜筒具有第一移动镜筒，第二移动镜筒和第三移动镜筒。第一移动筒具有对应于聚焦操作配置的第一凸轮槽，并且保持用于聚焦操作的光学系统。第二移动筒具有第二凸轮槽，并且相对于第一移动筒设置。第三移动筒具有对应于变焦操作构造的第三凸轮槽，并且可相对于固定筒移动。第二凸轮槽对应于第三凸轮槽的驱动操作校正所述光学系统的位置。

8. 发明申请

US20100211901A1 ON-VEHICLE APPARATUS AND CONTENT PROVIDING METHOD 有权
标题翻译：车载装置和内容提供方法
公开(公告)号：US20100211901A1
公开(公告)日：2010-08-19
申请号：US12771430
申请日：2010-04-30
申请人： Yoshiyuki NEZU , Makoto Sasaki , Satoshi Yamazaki
发明人： Yoshiyuki NEZU , Makoto Sasaki , Satoshi Yamazaki
IPC分类号： G06F3/048
CPC分类号： G01C21/36 , G06F3/0482 , G08G1/096872 , G08G1/096883 , G08G1/0969 , G09B29/10 , H04B1/202
摘要： The present invention is applied to, for example, a multimedia terminal having a function of navigation equipment and a function of playing back video and switches a display from a map display to a source display also with source switching operators 13P, 13R. In addition, menus of upper and lower hierarchies are simultaneously displayed to accept operations through a touch panel and a remote commander. In addition to a press-operable main rotary operator, a press-operable sub rotary operator is provided on a side surface. Among operations accepted through the main rotary operator, only a specific operation relating to content processing is accepted through the sub rotary operator.
摘要翻译：本发明应用于例如具有导航设备的功能的多媒体终端和播放视频的功能，并且也可以用源交换运算器13P，13R将显示从地图显示切换到源显示。此外，同时显示上层和下层的菜单，以通过触摸面板和遥控器接受操作。除了按压操作的主旋转操作器之外，在侧面设置有压力可操作的副旋转操作器。在通过主旋转操作器接受的操作中，仅通过副旋转操作器接受与内容处理相关的具体操作。

9. 发明授权

US07751088B2 High-image-quality halftone process 失效
标题翻译：高图像质量的半色调过程
公开(公告)号：US07751088B2
公开(公告)日：2010-07-06
申请号：US11450326
申请日：2006-06-09
申请人： Satoshi Yamazaki , Toshiaki Kakutani
发明人： Satoshi Yamazaki , Toshiaki Kakutani
IPC分类号： H04N1/405
CPC分类号： H04N1/4053 , H04N1/4015
摘要： This invention provides a method for generating a dither matrix includes: setting an evaluation function for calculating an evaluation value of the dither matrix; providing a dither matrix as an initial state which stores in respective elements each of a plurality of threshold values for deciding presence or absence of dot formation for each pixel according to an input tone value; fixing an element for storing a threshold value in an increasing order from a smaller threshold value while transposing at least one of the plurality of threshold values stored in a part of the elements and a threshold value stored in another part of the elements; and outputting a dither matrix in which elements for storing are fixed with regard to at least part of the plurality of threshold values. The step of fixing an element for storing a threshold value includes: transposing mutually part of the threshold values whose elements for storing have not been fixed, among the plurality of threshold values; calculating an evaluation value of the dither matrix in which the threshold values have been transposed, using the evaluation function; fixing an element for storing a smallest evaluation threshold value among the threshold values whose elements for storing have not been fixed, according to a compliance of the evaluation value to a predetermined criterion; and repeating the steps from the transposing step to the fixing step until elements for storing at least part of the plurality of threshold values are fixed.
摘要翻译：本发明提供了一种产生抖动矩阵的方法，包括：设置用于计算抖动矩阵的评估值的评估函数; 提供抖动矩阵作为初始状态，其根据输入色调值在每个像素存储用于决定每个像素的存在或不存在点的多个阈值中的每个元素中的每个元素; 固定用于从更小的阈值以递增的顺序存储阈值的元件，同时转置存储在元件的一部分中的多个阈值中的至少一个和存储在元件的另一部分中的阈值; 并且输出其中关于多个阈值的至少一部分固定存储元件的抖动矩阵。固定用于存储阈值的元素的步骤包括：在多个阈值之间相互调整存储元素的一部分阈值尚未固定的部分; 使用评价函数计算已经转置了阈值的抖动矩阵的评估值; 根据评估值与预定标准的一致性，固定用于存储其用于存储的元素的阈值中的最小评估阈值的元素尚未固定; 并重复从转置步骤到定影步骤的步骤，直到存储至少部分多个阈值的元素是固定的。

10. 发明授权

US07726769B2 Determination of ink ejection amount error for a printer 有权
标题翻译：确定打印机的喷墨量错误
公开(公告)号：US07726769B2
公开(公告)日：2010-06-01
申请号：US12150710
申请日：2008-04-29
申请人： Satoshi Yamazaki , Toshiaki Kakutani
发明人： Satoshi Yamazaki , Toshiaki Kakutani
IPC分类号： B41J29/393
CPC分类号： B41J29/393
摘要： A plurality of same ink nozzle arrays are provided, and multiple color patches are printed with mutually different dot recording rates respectively using one of the same ink nozzle arrays. Color specification value of the plurality of color patches is measured for each same ink nozzle array. The ink ejection amount error of each same ink nozzle array is determined based on the color specification values of the plurality of color patches for each same ink nozzle array. It is also possible to select among the plurality of color patches a preferable color patch that is closest to a specified reference color patch, and to determine the ink ejection amount error from the dot recording rate of the preferable color patch.
摘要翻译：提供多个相同的墨水喷嘴阵列，并且分别使用相同的墨水喷嘴阵列之一以相互不同的点记录速率打印多个色块。对于每个相同的墨水喷嘴阵列测量多个色块的颜色规格值。基于每个相同的墨水喷嘴阵列的多个色标的颜色规格值来确定每个相同的墨水喷嘴阵列的喷墨量误差。还可以在多个色标中选择最接近指定的参考色块的优选色标，并且从优选色标的点记录速率确定墨喷射量误差。

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