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1. 发明授权

US4737153A Reinforced therapeutic tube 失效
标题翻译：加强治疗管
公开(公告)号：US4737153A
公开(公告)日：1988-04-12
申请号：US10965
申请日：1987-02-04
申请人： Hidehiko Shimamura , Yoshihiko Yamada , Hiroyuki Akasu , Akio Ohmory , Toshiaki Takagi
发明人： Hidehiko Shimamura , Yoshihiko Yamada , Hiroyuki Akasu , Akio Ohmory , Toshiaki Takagi
IPC分类号： A61M16/04 , A61M25/00 , A61M27/00
CPC分类号： A61M16/04
摘要： A reinforced therapeutic tube which is excellent in kink resistance, pressure resistance and flexibility. The tube is made of an elastomeric material with a reinforcing material spirally embedded into the tube wall, and at least one of the tubular parts where no spiral reinforcing material exists. The tip end of the reinforcing material which is wound in spiral shape is bent parallel to the inside surface of the tube and inward of the tube for at least one or more pitches of the spiral, and at least the tip of the reinforcing material bent is buried into the inside wall of the tube.
摘要翻译：一种加压治疗管，耐扭结性，耐压性和柔韧性优异。该管由弹性体材料制成，其具有螺旋地嵌入管壁中的增强材料，以及不存在螺旋增强材料的至少一个管状部件。缠绕成螺旋形状的增强材料的前端与管的内表面平行并且向内弯曲至少一个或多个螺距的间距弯曲，至少弯曲的增强材料的尖端为埋入管内壁。

2. 发明授权

US4874522A Polysulfone hollow fiber membrane and process for making the same 失效
标题翻译：聚砜中空纤维膜及其制造方法
公开(公告)号：US4874522A
公开(公告)日：1989-10-17
申请号：US205079
申请日：1988-06-10
申请人： Takehiko Okamoto , Akio Ohmory , Akinori Sueoka , Ichiro Kawata , Hiroyuki Akasu
发明人： Takehiko Okamoto , Akio Ohmory , Akinori Sueoka , Ichiro Kawata , Hiroyuki Akasu
IPC分类号： B01D69/02 , B01D69/08 , B01D71/68 , D01D5/24
CPC分类号： B01D69/02 , B01D69/08 , B01D71/68 , D01D5/24
摘要： The polysulfone hollow fiber membrane provided by the present invention can prohibit bacteria, bacilli, viruses and the like, and is therefore useful, besides as an industrial filter for water purification, as a membrane for body fluid filtration or condensation. In particular, the polysulfone hollow fiber membrane is, being excellent in removing .beta..sub.2 -MG, markedly useful as a membrane for treating body fluid such as hemodialysis and hemofiltration.

3. 发明授权

US4251567A Process for producing a fibrous milk protein product 失效
标题翻译：纤维性乳蛋白制品的制造方法
公开(公告)号：US4251567A
公开(公告)日：1981-02-17
申请号：US944525
申请日：1978-09-21
申请人： Shuzo Ohyabu , Syuji Kawai , Hiroyuki Akasu , Takeo Akiya , Keiji Matsumura , Naoki Yagi , Kwang Young Kim , Tarushige Nakaji
发明人： Shuzo Ohyabu , Syuji Kawai , Hiroyuki Akasu , Takeo Akiya , Keiji Matsumura , Naoki Yagi , Kwang Young Kim , Tarushige Nakaji
IPC分类号： A23J3/00 , A23J3/10 , A23J3/28 , A23J1/20
CPC分类号： A23J3/285 , A23J3/28 , Y10S426/802
摘要： A fibrous milk protein product having a high tensile elongation (115 to 380%) and an excellent stability to hot water cooking (tolerant to treatment in hot water of 135.degree. C. for 4 minutes) which is produced by forming the starting milk protein into a fibrous composition and then treating the fibrous composition in an aqueous solution containing at least one of sodium, potassium and calcium salts and also an aldehyde type crosslinking agent having a ratio of molecular weight (M) to number of aldehyde groups (n) of 120 to 360 (e.g. lactose) at a pH of 2.5 to 6.5 and at 100.degree. to 140.degree. C. for 20 minutes to 3 hours.
摘要翻译：一种具有高拉伸伸长率（115-380％）和对热水烹饪（耐受135℃热水处理4分钟）的优异稳定性的纤维性乳蛋白产品，其通过将起始乳蛋白形成为纤维组合物，然后在含有钠，钾和钙盐中的至少一种的水溶液中处理纤维组合物，还有一种醛类交联剂，其分子量（M）与醛基数（n）的比值为120 至360（例如乳糖），pH为2.5至6.5，在100至140℃下进行20分钟至3小时。

4. 发明授权

US5340480A Polysulfone-based hollow fiber membrane and process for manufacturing the same 失效
标题翻译：聚砜基中空纤维膜及其制造方法
公开(公告)号：US5340480A
公开(公告)日：1994-08-23
申请号：US53074
申请日：1993-04-26
申请人： Ichiro Kawata , Takehiko Okamoto , Hiroyuki Akasu , Kensaku Komatsu
发明人： Ichiro Kawata , Takehiko Okamoto , Hiroyuki Akasu , Kensaku Komatsu
IPC分类号： B01D67/00 , B01D69/08 , B01D71/68 , D01F1/08
CPC分类号： B01D71/68 , B01D67/0011 , B01D69/08 , B01D2323/08 , B01D2323/12 , B01D2325/022 , B01D2325/20 , B01D2325/34
摘要： The polysulfone hollow fiber membrane of the invention has an inner dense skin layer composed of a polysulfone and a less amount of a polyvinylpyrrolidone, a content of the polyvinylpyrrolidone in the dense skin layer being higher than that in an outer surface layer. This membrane has excellent biocompatibility and antithrombogenetic ability and is, therefore, useful in body fluid treatment, such as hemodialysis, hemofiltration and hemoconcentration, without clogging with thrombi.
摘要翻译：本发明的聚砜中空纤维膜具有由聚砜和少量的聚乙烯吡咯烷酮构成的内部致密表皮层，致密表皮层中聚乙烯吡咯烷酮的含量高于外表面层中的含量。该膜具有优异的生物相容性和抗血栓发生能力，因此可用于体液治疗，如血液透析，血液滤过和血液浓缩，无栓塞堵塞。

5. 发明授权

US4650457A Apparatus for extracorporeal lung assist 失效
标题翻译：体外肺辅助装置
公开(公告)号：US4650457A
公开(公告)日：1987-03-17
申请号：US766751
申请日：1985-08-16
申请人： Tohru Morioka , Hidenori Terasaki , Hiroyuki Akasu , Akiyoshi Nakano , Kohichi Takase
发明人： Tohru Morioka , Hidenori Terasaki , Hiroyuki Akasu , Akiyoshi Nakano , Kohichi Takase
IPC分类号： A61M1/10 , A61M1/03
CPC分类号： A61M1/1086 , A61M1/1037 , Y10S128/03
摘要： An apparatus for extracorporeal lung assist including a pump device having a flexible blood reservoir housed in a rigid housing, which pump device is able to expand and contract the blood reservoir by pumping liquid into and from the housing, thereby repeating cycles of blood feed and blood take-off, a blood take-off circuit connected to the in-flow side of a membrane artificial lung and in which the pump device is disposed, a blood feed circuit connected to the out-flow side of the membrane artificial lung, the two circuits forming an extracorporeal circulation circuit, a liquid circulation circuit connected to the housing of the pump device and having a flexible liquid reservoir disposed therein with a head provided relative to the pump device, and sensors for detecting the expansion and contraction of the liquid reservoirs, whereby blood in-flow and out-flow paths are controlled so that when the blood reservoir is contracted, blood is drawn into the blood reservoir under subpressure in the housing, whereas when the blood reservoir is expanded, blood is discharged from the blood reservoir under pressure developed in the housing. The apparatus of the invention provides respiratory aids safely for a long period of time and is therefore useful for treatment of acute respiratory failure cases.
摘要翻译：一种用于体外肺辅助的装置，包括具有容纳在刚性壳体中的柔性血液储存器的泵装置，所述泵装置能够通过将液体泵入和从壳体中泵送液体来扩张和收缩血液储存器，从而重复血液供给和血液循环起飞，连接到膜人造肺的流入侧的血液输出回路，其中设置有泵装置;血液供给回路，连接到膜人造肺的流出侧，两个形成体外循环回路的电路，连接到泵装置的壳体并具有设置在其中的柔性储液器的液体循环回路，其具有相对于泵装置设置的头部，以及用于检测液体储存器的膨胀和收缩的传感器，由此控制血液流入和流出路径，使得当血液储存器收缩时，血液在负压下被吸入血液储存器而在血液储存器膨胀的时候，血液在血液储存器中在壳体内产生的压力下排出。本发明的装置长时间安全地提供呼吸辅助剂，因此可用于治疗急性呼吸衰竭病例。

6. 发明授权

US5192320A Artificial lung and method of using it 失效
标题翻译：人造肺及其使用方法
公开(公告)号：US5192320A
公开(公告)日：1993-03-09
申请号：US488452
申请日：1990-02-23
申请人： Takanori Anazawa , Kazutaka Murata , Hiroyuki Akasu , Rishichi Mimura
发明人： Takanori Anazawa , Kazutaka Murata , Hiroyuki Akasu , Rishichi Mimura
IPC分类号： A61M1/16 , B01D67/00 , B01D69/02 , B01D69/08 , B01D71/26 , B01F3/04 , B01F5/04
CPC分类号： B01F5/045 , B01D67/0025 , B01D69/02 , B01D69/08 , B01D71/26 , B01F3/04269 , A61M1/1698 , B01D2325/02 , B01F2003/0439
摘要： A membrane-type artificial lung adapted to perform exchange of gases between blood and a gas through a membrane by passing blood over one side of the membrane and oxygen or an oxygen-containing gas over the other side, said membrane being a hollow fiber membrane which is composed mainly of a polyolefin, has an inside diameter of 10 to 500 micrometers, a thickness of 5 to 100 micrometers, a porosity of 7 to 50% and an oxygen flux, Q(O.sub.2), of at least 1.times.10.sup.-6 [cm.sup.3 (STP)/(cm.sup.2.sec.cmHg)] and is substantially impermeable to ethanol.
摘要翻译：一种膜型人造肺，其适于通过使血液在膜的一侧上通过血液和通过膜的气体与氧气或含氧气体在另一侧之间进行气体交换，所述膜是中空纤维膜，其中主要由聚烯烃组成，内径为10至500微米，厚度为5至100微米，孔隙率为7至50％，氧气通量Q（O2）至少为1×10-6 [cm3 （STP）/（cm2.sec.cmHg）]，并且对乙醇是基本上不可渗透的。

7. 发明授权

US4911846A Fluid treating apparatus and method of using it 失效
标题翻译：流体处理装置及其使用方法
公开(公告)号：US4911846A
公开(公告)日：1990-03-27
申请号：US354794
申请日：1989-05-22
申请人： Hiroyuki Akasu , Rishichi Mimura , Takao Migaki , Takashi Yamauchi , Michio Kusachi
发明人： Hiroyuki Akasu , Rishichi Mimura , Takao Migaki , Takashi Yamauchi , Michio Kusachi
IPC分类号： A61M1/14 , A61M1/18 , B01D63/02
CPC分类号： B01D63/026 , B01D63/02 , B01D2313/025 , B01D2313/38
摘要： Disclosed is a fluid treating apparatus of hollow fiber type. The apparatus can prevent channeling or stagnation of the fluid which flows inside it by specifying the densities of the hollow fibers and the warps forming a hollow fiber sheet and the laminating conditions for laminating the hollow fiber sheets to form a laminate which is to be housed in a housing.

8. 发明授权

US4275084A Formed food product of microfibrillar protein and process for the production thereof 失效
标题翻译：微纤维蛋白的成型食品及其生产方法
公开(公告)号：US4275084A
公开(公告)日：1981-06-23
申请号：US102483
申请日：1979-12-11
申请人： Shuzo Ohyabu , Syozi Kurosaki , Keiji Matsumura , Hiroyuki Akasu , Takeo Akiya , Naoki Yagi , Kwang Y. Kim , Tarushige Nakaji , Akiko Miyanaka
发明人： Shuzo Ohyabu , Syozi Kurosaki , Keiji Matsumura , Hiroyuki Akasu , Takeo Akiya , Naoki Yagi , Kwang Y. Kim , Tarushige Nakaji , Akiko Miyanaka
IPC分类号： A23J3/00 , A23J3/10 , A23J3/22 , D01F4/00 , D01F4/04
CPC分类号： A23J3/227 , D01F4/00 , Y10S426/802
摘要： There is disclosed a formed food product of microfibrillar protein comprising a bundle of microfibrillar protein having a diameter of fiber of 10.mu. or less and a high heat resistance (A) and a microfibrillar protein having a diameter of fiber of 10.mu. or less and a low heat resistance (B) and optionally one or more fillers and/or other additives, which has similar structure and texture to those of cooked natural meats and has excellent stability to hot water cooking, excellent shape retention and good texture, and hence is useful as an artificial meat product.
摘要翻译：公开了一种微纤维蛋白质的成形食品，其包含纤维直径为10μm以下，高耐热性（A）和纤维直径为10μm以下的微原纤维的纤维束，低耐热性（B）和任选的一种或多种填充剂和/或其它添加剂，其具有与煮熟的天然肉类相似的结构和质地，并且对热水烹饪具有优异的稳定性，优异的保形性和良好的质地，因此是有用的作为人造肉制品。

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