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1. 发明授权

US4617263A Method for quantitative determination of acetylputrescine in a mixture 失效
标题翻译：用于定量测定混合物中乙酰肌氨酸的方法
公开(公告)号：US4617263A
公开(公告)日：1986-10-14
申请号：US776162
申请日：1985-09-13
申请人： Hideaki Yamada , Shogo Otsuji , Kimiyasu Isobe , Kuniyoshi Matsunaga , Tadahiko Inukai
发明人： Hideaki Yamada , Shogo Otsuji , Kimiyasu Isobe , Kuniyoshi Matsunaga , Tadahiko Inukai
IPC分类号： G01N33/52 , C12Q1/26 , G01N33/50
CPC分类号： C12Q1/26
摘要： A rapid and reliable method is proposed for the quantitative determination of the individual free and acetylated polyamines, i.e. spermine, spermidine, putrescine, acetylspermine, N.sup.1 - and N.sup.8 -acetylspermidines and acetylputrescine in the body fluid of a patient suffering cancer or other diseases to facilitate diagnosis and therapeutic treatment. The method comprises subjecting the aqueous fluid to several enzymatic oxidative decomposition reactions of the polyamines in sequence or in combination by use of the 4 enzymes, i.e. polyamine oxidase AT-1, polyamine oxidase PC-3, putrescine oxidase and acetylputrescine oxidase, and determining, preferably photometrically, the amount of hydrogen peroxide formed as a byproduct in each of the reaction steps followed by setting up a set of simultaneous equations to give the respective amounts of the individual polyamines as a function of the amounts of the hydrogen peroxide formed in the reaction steps and solving the simultaneous equations.
摘要翻译：提出了一种快速可靠的方法，用于定量测定患有癌症或其他疾病的患者的体液中的个体游离和乙酰化多胺，即精胺，亚精胺，腐胺，乙酰精胺，N1-和N8-乙酰精氨酸和乙酰胞嘧啶诊断和治疗。该方法包括通过使用4种酶，即多胺氧化酶AT-1，多胺氧化酶PC-3，腐胺氧化酶和乙酰胸腺嘧啶氧化酶，依次或组合地对含水液体进行多种酶的氧化分解反应，优选光度计，在每个反应步骤中作为副产物形成的过氧化氢的量随后建立一组联立方程，以得到作为在反应中形成的过氧化氢的量的函数的各个多胺的各自量步骤和求解联立方程。

2. 发明授权

US4550078A Method for the quantitative determination of individual polyamine components in a mixture 失效
标题翻译：用于定量测定混合物中单个多胺组分的方法
公开(公告)号：US4550078A
公开(公告)日：1985-10-29
申请号：US495677
申请日：1983-05-18
申请人： Hideaki Yamada , Shogo Otsuji , Kimiyasu Isobe , Kuniyoshi Matsunaga , Tadahiko Inukai
发明人： Hideaki Yamada , Shogo Otsuji , Kimiyasu Isobe , Kuniyoshi Matsunaga , Tadahiko Inukai
IPC分类号： G01N33/52 , C12Q1/26 , G01N33/50
CPC分类号： C12Q1/26
摘要： A rapid and reliable method is proposed for the quantitative determination of the individual free and acetylated polyamines, i.e. spermine, spermidine, putrescine, acetylspermine, N.sup.1 - and N.sup.8 -acetylspermidines and acetylputrescine in the body fluid of a patient suffering cancer or other deseases to facilitate diagnosis and therapeutic treatment. The method comprises subjecting the aqueous fluid to several enzymatic oxidative decomposition reactions of the polyamines in sequence or in combination by use of the 4 enzymes, i.e. polyamine oxidase AT-1, polyamine oxidase PC-3, putrescine oxidase and acetylputrescine oxidase, and determining, preferably photometrically, the amount of hydrogen peroxide formed as a byproduct in each of the reaction steps followed by setting up a set of simultaneous equations to give the respective amounts of the individual polyamines as a function of the amounts of the hydrogen peroxide formed in the reaction steps and solving the simultaneous equations.
摘要翻译：提出了一种快速可靠的方法，用于定量测定患有癌症或其他疾病的患者的体液中的各种游离和乙酰化多胺，即精胺，亚精胺，腐胺，乙酰精胺，N1-和N8-乙酰哌啶和乙酰吗啡诊断和治疗。该方法包括通过使用4种酶，即多胺氧化酶AT-1，多胺氧化酶PC-3，腐胺氧化酶和乙酰胸腺嘧啶氧化酶，依次或组合地对含水液体进行多种酶的氧化分解反应，优选光度计，在每个反应步骤中作为副产物形成的过氧化氢的量随后建立一组联立方程，以得到作为在反应中形成的过氧化氢的量的函数的各个多胺的各自量步骤和求解联立方程。

3. 发明授权

US4373026A Microbial polyamide oxidase PC-3 and process for preparation thereof 失效
标题翻译：微生物聚酰胺氧化酶PC-3及其制备方法
公开(公告)号：US4373026A
公开(公告)日：1983-02-08
申请号：US216302
申请日：1980-12-12
申请人： Hideaki Yamada , Yoshiki Tani , Kimiyasu Isobe
发明人： Hideaki Yamada , Yoshiki Tani , Kimiyasu Isobe
IPC分类号： C12N9/06 , C12Q1/26 , C12R1/82 , C12P21/00
CPC分类号： C12N9/0026 , C12Q1/26 , Y10S435/935
摘要： A novel polyamine oxidase, polyamine oxidase PC-3, takes an important role participating in decomposition and metabolism and polyamines such as spermidine and spermine.
摘要翻译：一种新型多胺氧化酶多胺氧化酶PC-3在分解代谢和多胺如亚精胺和精胺中起重要作用。

4. 发明授权

US4371621A Microbial polyamine oxidase AT-1 失效
标题翻译：微生物多胺氧化酶AT-1
公开(公告)号：US4371621A
公开(公告)日：1983-02-01
申请号：US216301
申请日：1980-12-12
申请人： Hideaki Yamada , Yoshiki Tani , Kimiyasu Isobe
发明人： Hideaki Yamada , Yoshiki Tani , Kimiyasu Isobe
IPC分类号： C12N9/06 , C12R1/66 , C12R1/82
CPC分类号： C12N9/0026 , Y10S435/913
摘要： A novel polyamine oxidase, polyamine oxidase AT-1, takes an important role participating in decomposition and metabolism of polyamines such as spermidine and spermine.
摘要翻译：一种新型多胺氧化酶多胺氧化酶AT-1在多胺如亚精胺和精胺的分解和代谢中起重要作用。

5. 发明授权

US09410241B2 Method for separating surface layer or growth layer of diamond 有权
标题翻译：分离金刚石表面层或生长层的方法
公开(公告)号：US09410241B2
公开(公告)日：2016-08-09
申请号：US12439887
申请日：2007-08-31
申请人： Yoshiaki Mokuno , Akiyoshi Chayahara , Hideaki Yamada
发明人： Yoshiaki Mokuno , Akiyoshi Chayahara , Hideaki Yamada
IPC分类号： C23C16/01 , C23C16/27 , C23C16/56 , C25F3/00 , C30B29/04 , C30B31/22 , C30B33/06
CPC分类号： C23C16/01 , C23C16/27 , C23C16/56 , C25F3/00 , C30B29/04 , C30B31/22 , C30B33/06
摘要： The present invention provides a method for separating a surface layer of a diamond, which comprises implanting ions into a diamond to form a non-diamond layer near a surface of the diamond; and etching the non-diamond layer in the diamond by applying an alternating-current voltage across electrodes in an electrolytic solution; and a method for separating a grown layer of a diamond, which further comprises the step of growing a diamond by a vapor-phase synthesis method, after forming a non-diamond layer according to the above-described method. The invention is applicable to various single-crystal and polycrystal diamonds. More specifically, even with a large single-crystal diamond, a portion of the single-crystal diamond can be efficiently separated in a reusable form in a relatively short period of time.
摘要翻译：本发明提供一种用于分离金刚石的表面层的方法，其包括将离子注入金刚石以在金刚石的表面附近形成非金刚石层; 以及通过在电解液中跨越电极施加交流电压来蚀刻金刚石中的非金刚石层; 以及分离金刚石生长层的方法，其还包括根据上述方法在形成非金刚石层之后通过气相合成法生长金刚石的步骤。本发明适用于各种单晶和多晶钻石。更具体地，即使使用大的单晶金刚石，一部分单晶金刚石可以在相对较短的时间内以可重复使用的形式被有效地分离。

6. 发明授权

US08940266B2 Large diamond crystal substrates and methods for producing the same 有权
标题翻译：大型金刚石晶体基板及其制造方法
公开(公告)号：US08940266B2
公开(公告)日：2015-01-27
申请号：US12646163
申请日：2009-12-23
申请人： Hideaki Yamada , Akiyoshi Chayahara , Yoshiaki Mokuno , Shinichi Shikata
发明人： Hideaki Yamada , Akiyoshi Chayahara , Yoshiaki Mokuno , Shinichi Shikata
IPC分类号： B01J3/06 , C30B33/06 , C30B23/00 , B01J19/08 , C23C14/00 , C30B29/04 , C30B33/00 , C01B31/06 , C30B25/00
CPC分类号： C30B29/04 , C01B32/25 , C01B32/28 , C30B23/00 , C30B25/00 , C30B33/00 , C30B33/06
摘要： The present invention provides a method for producing a large substrate of single-crystal diamond, including the steps of preparing a plurality of single-crystal diamond layers separated form an identical parent substrate, placing the single-crystal diamond layers in a mosaic pattern on a flat support, and growing a single-crystal diamond by a vapor-phase synthesis method on faces of the single-crystal diamond layers where they have been separated from the parent substrate.According to the method of the invention, a mosaic single-crystal diamond having a large area and good quality can be produced relatively easily.
摘要翻译：本发明提供一种用于制造大型单晶金刚石基板的方法，包括以下步骤：制备从相同的母基板分离的多个单晶金刚石层，将单晶金刚石层以马赛克图案放置在平面支撑，并通过气相合成法在单晶金刚石层的与母体基底分离的面上生长单晶金刚石。根据本发明的方法，可以相对容易地制造面积大，质量好的马赛克单晶金刚石。

7. 发明授权

US08575919B2 Inclination detection method and inclination detection apparatus 有权
标题翻译：倾斜检测方法和倾斜检测装置
公开(公告)号：US08575919B2
公开(公告)日：2013-11-05
申请号：US12843818
申请日：2010-07-26
申请人： Hideaki Yamada , Michihiro Nagaishi
发明人： Hideaki Yamada , Michihiro Nagaishi
IPC分类号： G01P13/00 , G01P15/00
CPC分类号： G01C9/10 , G01C9/06
摘要： An inclination detection method is disclosed, which uses a pair of electrodes placed so as to face each other and having a fixed positional relation and an electric conductor which can move between the pair of electrodes, wherein the pair of electrodes is in either a conducting state or a nonconducting state depending on the position of the movable electric conductor, the conducting state in a predetermined period is expressed as any one of a plurality of level values, and a movement state of the pair of electrodes is estimated based on which of the plurality of level values the conducting state takes on.
摘要翻译：公开了一种倾斜检测方法，其使用一对彼此相对放置并具有固定的位置关系的电极和能够在该对电极之间移动的电导体，其中该对电极处于导通状态或取决于可动电导体的位置的不导电状态，将预定周期中的导通状态表示为多个电平值中的任何一个，并且基于多个电极中的哪一个来估计该对电极的移动状态的执行状态的水平值。

8. 发明授权

US08339160B2 Clock generating device and jitter reducing method in the clock generating device 有权
标题翻译：时钟发生装置中的时钟发生装置和抖动减少方法
公开(公告)号：US08339160B2
公开(公告)日：2012-12-25
申请号：US12619947
申请日：2009-11-17
申请人： Hideaki Yamada
发明人： Hideaki Yamada
IPC分类号： H03B21/00
CPC分类号： G06F1/08 , G06F1/025
摘要： A clock generating device includes: a DDS circuit that generates a periodic signal; and a comparator that compares an input signal and a reference signal and outputs a binary signal. The clock generating device includes a rate-of-change correcting unit that applies correction for increasing a rate of change at a crossing point with the reference signal to the periodic signal generated by the DDS circuit.
摘要翻译：时钟发生装置包括：产生周期信号的DDS电路; 以及比较器，其比较输入信号和参考信号，并输出二进制信号。时钟发生装置包括变化率校正单元，其对与DDS电路产生的周期信号相对应的参考信号将交叉点的变化率提高的校正。

9. 发明申请

US20100260274A1 COMMUNICATION METHOD AND COMMUNICATION SYSTEM 有权
标题翻译：通信方法与通信系统
公开(公告)号：US20100260274A1
公开(公告)日：2010-10-14
申请号：US12756888
申请日：2010-04-08
申请人： Hideaki Yamada
发明人： Hideaki Yamada
IPC分类号： H04L27/00
CPC分类号： H03M5/14
摘要： A communication method includes: (a) dividing one bit data group into a plurality of bit groups, the one bit data group being taken out from a plurality of bit data groups defined by a communication protocol for transmitting predetermined information, and exerting no substantial influence on the predetermined information even when arbitrarily inverting a value of the bit; (b) determining whether or not the values of the bits constituting the bit group are all the same by each of the plurality of bit groups divided into in step (a); (c) inverting at least one of the values of the bits of the bit group determined in step (b) that the values of the bits are all the same; and (d) arranging the plurality of bit groups, each of which has at least one of the values of the bits inverted in step (c), in the plurality of bit data groups except the one bit data group at regular intervals.
摘要翻译：一种通信方法包括：（a）将一个比特数据组划分成多个比特组，从由用于发送预定信息的通信协议定义的多个比特数据组中取出一比特数据组，并且不施加实质影响即使当任意地反转位的值时，也可以对预定信息进行处理; （b）通过步骤（a）中划分的多个比特组中的每一个来确定构成比特组的比特的值是否全部相同; （c）将在步骤（b）中确定的比特组的比特的值中的至少一个值反转为比特的值全部相同; 以及（d）在所述多个比特数据组中排列多个比特组，每个比特组具有在步骤（c）中反转的比特值中的至少一个的值，该比特数据组除了一个比特数据组以规则的间隔。

10. 发明申请

US20100186514A1 Surface acoustic wave pressure sensor 有权
标题翻译：表面声波压力传感器
公开(公告)号：US20100186514A1
公开(公告)日：2010-07-29
申请号：US12656209
申请日：2010-01-21
申请人： Akihiko Teshigahara , Hideaki Yamada
发明人： Akihiko Teshigahara , Hideaki Yamada
IPC分类号： G01L11/04
CPC分类号： G01L9/0025 , G01L9/008
摘要： A sensor chip has a substrate and a comb-teeth electrode arranged on the substrate. The sensor chip is fixed to a diaphragm structure to be distorted by receiving pressure, and is fixed to the diaphragm structure only through a predetermined fix area so as to detect the pressure. The fix area is defined on only a part of the sensor chip opposing to the diaphragm structure. The sensor chip is restrained by the diaphragm structure in a direction of transmitting surface acoustic wave. Flexibility of the sensor chip in a perpendicular direction approximately perpendicular to the wave transmitting direction is larger than that in the transmitting direction.
摘要翻译：传感器芯片具有布置在基板上的基板和梳齿电极。传感器芯片固定在膜片结构上，通过接受压力而变形，并且仅通过预定的固定区域固定到膜片结构，以便检测压力。固定区仅限于与隔膜结构相对的传感器芯片的一部分。传感器芯片在传播表面声波的方向上被隔膜结构约束。传感器芯片在大致垂直于波浪传播方向的垂直方向上的灵活性大于传送方向的灵敏度。

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