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1. 发明申请

US20100312538A1 APPARATUS FOR IN SILICO SCREENING, AND METHOD OF IN SILOCO SCREENING 审中-公开
标题翻译： SILICO筛选设备及SILOO筛选方法
公开(公告)号：US20100312538A1
公开(公告)日：2010-12-09
申请号：US12734515
申请日：2008-11-12
申请人： Hideaki Umeyama , Daisuke Takaya , Mayuko Shitaka , Kazuhiko Kanou , Genki Terashi , Katsuichiro Komatsu
发明人： Hideaki Umeyama , Daisuke Takaya , Mayuko Shitaka , Kazuhiko Kanou , Genki Terashi , Katsuichiro Komatsu
IPC分类号： G06G7/58 , G06G7/48
CPC分类号： G16C20/60 , G16B35/00
摘要： The present invention provides an apparatus including a compound database which has been produced by extracting fingerprints of compound related to plural atoms in a compound for each candidate compound, characterized by extracting the fingerprints of compound of binding compounds that are already known to bind to family proteins having 3-dimensional structure that is identical or similar to that of target protein, together with the 3-dimensional coordinates that have been converted into the coordinate system of the target protein, to produce a fingerprint set of binding compound, and for a candidate compound stored in the compound database, computing the 3-dimensional structure of the candidate compound with respect to the target protein, so that the interaction score based on the root-mean-square deviation of a unit of fingerprint of compound calculated on the basis of the 3-dimensional coordinates of the fingerprint set of binding compound is optimized.
摘要翻译：本发明提供了一种装置，其包括通过提取每种候选化合物的化合物中与多个原子相关的化合物的指纹而产生的化合物数据库，其特征在于提取已知结合家族蛋白的结合化合物的化合物的指纹具有与靶蛋白相同或相似的3维结构，以及已经转化为靶蛋白的坐标系的3维坐标，以产生结合化合物的指纹集，以及候选化合物存储在化合物数据库中，计算相对于目标蛋白质的候选化合物的3维结构，使得基于根据化合物计算的化合物指纹单位的均方根偏差的相互作用评分优化了结合化合物指纹集的3维坐标。

2. 发明申请

US20100057420A1 APPARATUS FOR PROCESSING 3-DIMENSIONAL STRUCTURE OF PROTEIN, METHOD OF PROCESSING 3-DIMENSIONAL STRUCTURE OF PROTEIN, AND PROGRAM 审中-公开
标题翻译：用于加工蛋白质三维结构的装置，处理蛋白质三维结构的方法和程序
公开(公告)号：US20100057420A1
公开(公告)日：2010-03-04
申请号：US12312634
申请日：2007-11-21
申请人： Hideaki Umeyama , Mayuko Shitaka , Genki Terashi , Kazuhiko Kanou , Katsuichiro Komatsu , Mitsuo Iwadat
发明人： Hideaki Umeyama , Mayuko Shitaka , Genki Terashi , Kazuhiko Kanou , Katsuichiro Komatsu , Mitsuo Iwadat
IPC分类号： G06G7/48
CPC分类号： C07K14/00 , G16B15/00 , G16B30/00
摘要： An apparatus for processing 3-dimensional structure of protein includes a control unit and a storage unit, wherein the storage unit stores 3-dimensional structure information of protein, and the control unit predicts 3-dimensional structure information of protein after the mutation when an arbitrary amino acid residue A in the 3-dimensional structure information of protein stored in the storage unit is mutated into another amino acid residue a, thereof from the 3-dimensional structure information of protein before and after the mutation, collects the amino acid residue A, the amino acid residue a, environment information P, and environment information p, which are related to each other, as information on environmental change, when the environment information P around the amino acid residue A before the mutation changes to the environment information p around the amino acid residue a after the mutation, thereby storing information on the environmental change in the storage unit.
摘要翻译：用于处理蛋白质的三维结构的装置包括控制单元和存储单元，其中存储单元存储蛋白质的3维结构信息，并且控制单元预测突变后蛋白质的三维结构信息，当任意存储在存储单元中的蛋白质的3维结构信息中的氨基酸残基A从突变前后的蛋白质的3维结构信息突变成另一个氨基酸残基a，收集氨基酸残基A，当突变前后的氨基酸残基A周围的环境信息P变化为环境信息p周围的环境信息p时，将彼此相关的氨基酸残基a，环境信息P和环境信息p作为环境变化的信息突变后的氨基酸残基a，从而存储关于存储单元中的环境变化的信息。

3. 发明授权

US5504356A Semiconductor accelerometer 失效
标题翻译：半导体加速度计
公开(公告)号：US5504356A
公开(公告)日：1996-04-02
申请号：US152505
申请日：1993-11-16
申请人： Yukihiro Takeuchi , Toshimasa Yamamoto , Yoshinori Ohtsuka , Shigeyuki Akita , Tadashi Hattori , Kazuhiko Kanou , Hirotane Ikeda
发明人： Yukihiro Takeuchi , Toshimasa Yamamoto , Yoshinori Ohtsuka , Shigeyuki Akita , Tadashi Hattori , Kazuhiko Kanou , Hirotane Ikeda
IPC分类号： G01P15/08 , G01P15/12 , H01L29/78 , H01L29/84
CPC分类号： G01P15/124 , G01P15/0802
摘要： This invention aims at providing a novel semiconductor accelerometer comprising a smaller number of substrates and a production method thereof.An insulating film is formed on a main plane of a P-type silicon substrate, and a beam-like movable electrode is formed on the insulating film. Fixed electrodes are then formed on both sides of the movable electrode in self-alignment with the movable electrode by diffusing an impurity into the P-type silicon substrate, and the insulating film below the movable electrode is etched and removed. There is thus produced a semiconductor accelerometer comprising the P-type silicon substrate 1, the movable electrode 4 having the beam structure and disposed above the P-type silicon substrate 1 with a predetermined gap between them, and the fixed electrodes 8, 9 consisting of the impurity diffusion layer and formed on both sides of the movable electrode 4 on the P-type silicon substrate 1 in self-alignment with the movable electrode 4. This sensor can detect acceleration from the change (increase/decrease) of a current between the fixed electrodes 8 and 9 resulting from the displacement of the movable electrode 4 due to acceleration.
摘要翻译：本发明的目的在于提供一种新型的半导体加速度计，其包括较少数量的基板及其制造方法。在P型硅基板的主平面上形成绝缘膜，在绝缘膜上形成有束状的可动电极。然后通过将杂质扩散到P型硅衬底中，在可动电极的两侧与可动电极自对准地形成固定电极，蚀刻除去可动电极下面的绝缘膜。因此，制造了包括P型硅衬底1，具有光束结构的可动电极4并且在它们之间具有预定间隙并且设置在P型硅衬底1上方的固定电极8,9的半导体加速度计，该杂质扩散层形成在与可动电极4自对准的P型硅衬底1上的可动电极4的两侧。该传感器可以从电流的变化（增加/减少）固定电极8和9由于加速而由可动电极4的位移而产生。

4. 发明授权

US08876400B2 Thrust roller bearing and method for manufacturing thrust race thereof 有权
标题翻译：推力滚子轴承及其推力轮的制造方法
公开(公告)号：US08876400B2
公开(公告)日：2014-11-04
申请号：US13060709
申请日：2010-02-24
申请人： Kazuhiko Kanou , Tetsuya Takahashi
发明人： Kazuhiko Kanou , Tetsuya Takahashi
IPC分类号： F16C33/58 , F16C43/04 , F16C19/30 , F16C33/64 , F16C35/06 , B23P15/00
CPC分类号： F16C19/305 , B23P15/003 , F16C19/30 , F16C33/588 , F16C33/64 , F16C35/06 , Y10T29/49645
摘要： A thrust race of a thrust roller bearing has a race portion and a cylindrical portion extending from the race portion in an axial direction. At a plurality of locations along a circumferential direction on the cylindrical portion, cutout portions are formed such that each of the cutout portions is recessed in the axial direction from a distal edge of the cylindrical portion toward the race portion. A protrusion is provided at a portion closer to the race portion from a bottom edge of each of the cutout portions such that the protrusion protrudes in a radial direction from the cylindrical portion toward a side away from the race portion. The protrusion serves as a race-retaining locking portion to prevent a race from moving out from a mating member on which the race is mounted.
摘要翻译：推力滚子轴承的推力座圈具有一个座圈部分和一个从座圈部分沿轴向延伸的圆柱形部分。在圆筒部的圆周方向的多个位置上，形成有切口部，从而从圆筒部的远端朝向座部的方向从轴向凹入。在每个切口部分的底边缘处的靠近滚道部分的部分处设置突起，使得突出部沿径向从圆柱部分向远离滚道部分的一侧突出。突起用作挡圈保持锁定部分，以防止赛跑从安装有赛车的配合构件移出。

5. 发明申请

US20110158573A1 THRUST ROLLER BEARING AND METHOD FOR MANUFACTURING THRUST RACE THEREOF 有权
标题翻译：推力滚子轴承及其制造方法
公开(公告)号：US20110158573A1
公开(公告)日：2011-06-30
申请号：US13060709
申请日：2010-02-24
申请人： Hiroyuki Hara , Kazuhiko Kanou , Tomoyuki Yokota , Tetsuya Takahashi
发明人： Hiroyuki Hara , Kazuhiko Kanou , Tomoyuki Yokota , Tetsuya Takahashi
IPC分类号： F16C33/46 , F16C33/64 , F16C33/58
CPC分类号： F16C19/305 , B23P15/003 , F16C19/30 , F16C33/588 , F16C33/64 , F16C35/06 , Y10T29/49645
摘要： A thrust race of a thrust roller bearing has a race portion and a cylindrical portion extending from the race portion in an axial direction. At a plurality of locations along a circumferential direction on the cylindrical portion, cutout portions are formed such that each of the cutout portions is recessed in the axial direction from a distal edge of the cylindrical portion toward the race portion. A protrusion is provided at a portion closer to the race portion from a bottom edge of each of the cutout portions such that the protrusion protrudes in a radial direction from the cylindrical portion toward a side away from the race portion. The protrusion serves as a race-retaining locking portion to prevent a race from moving out from a mating member on which the race is mounted.
摘要翻译：推力滚子轴承的推力座圈具有一个座圈部分和一个从座圈部分沿轴向延伸的圆柱形部分。在圆筒部的圆周方向的多个位置上，形成有切口部，从而从圆筒部的远端朝向座部的方向从轴向凹入。在每个切口部分的底边缘处的靠近滚道部分的部分处设置突起，使得突出部沿径向从圆柱部分向远离滚道部分的一侧突出。突起用作挡圈保持锁定部分，以防止赛跑从安装有赛车的配合构件移出。

6. 发明授权

US5587417A Rubber composition for tire tread 失效
标题翻译：轮胎胎面橡胶组合物
公开(公告)号：US5587417A
公开(公告)日：1996-12-24
申请号：US403720
申请日：1995-03-14
申请人： Shinsuke Nakane , Kazuhiko Kanou , Takatsugu Hashimoto
发明人： Shinsuke Nakane , Kazuhiko Kanou , Takatsugu Hashimoto
IPC分类号： B60C1/00 , C08K3/04 , C08K5/09 , C08L7/00 , C08L9/00 , C08K3/00
CPC分类号： C08K3/04 , B60C1/0016 , C08K5/09
摘要： A rubber composition for a tire tread which is provided by the present invention can be obtained by blending 100 parts by weight of a natural rubber and/or a diene synthetic rubber with40 to 100 parts by weight of a carbon black having characteristic values of a cetyltriammonium bromide adsorption specific surface area (CTAB) being 90 to 220 m.sup.2 /g and a 24M4DBP absorption value being 90 to 140 ml/100 g, and0.1 to 20 parts by weight of an organic unsaturated fatty acid having two or more carbon double bonds in its molecule which includes 10% by weight or more of a conjugated diene acid having at least one pair of two carbon double bonds in a conjugated relation in its molecule.This rubber composition for a tire tread can be suitably used for a pneumatic tire, particularly a pneumatic tire for heavy load having an excellent wear resistance.
摘要翻译： PCT No.PCT / JP93 / 00971 Sec。 371日期：1995年3月14日 102（e）1995年3月14日PCT PCT 1993年7月14日PCT公布。出版物WO93 / 日本特开1993年10月14日由本发明提供的轮胎胎面用橡胶组合物可以通过将100重量份的天然橡胶和/或二烯合成橡胶与40〜100重量份的炭黑十六烷基三甲基溴化铵吸附比表面积（CTAB）的特征值为90〜220m2 / g，24M4DBP吸收值为90〜140ml / 100g，0.1〜20重量份具有2个或更多的碳双键，其包含10重量％以上的分子中具有共轭关系的至少一对双碳双键的共轭二烯酸。用于轮胎胎面的这种橡胶组合物可以适用于充气轮胎，特别是具有优异耐磨性的重载充气轮胎。

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