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1. 发明申请

US20120029088A1 ANTI-ANXIETY COMPOSITION 审中-公开
标题翻译：抗坏血酸组合物
公开(公告)号：US20120029088A1
公开(公告)日：2012-02-02
申请号：US13188328
申请日：2011-07-21
申请人： Hideaki HARA , Atsushi OOYAGI , Takashi ISHIBASHI
发明人： Hideaki HARA , Atsushi OOYAGI , Takashi ISHIBASHI
IPC分类号： A61K31/122 , C07C49/647 , A61P25/22 , C07C49/743
CPC分类号： A61K31/122 , A23L2/52 , A23L33/105 , A61K2300/00
摘要： This invention provides a highly safe anti-anxiety composition that can be used for treatment or prevention of anxiety disorders. Such anti-anxiety composition comprises, as an active ingredient, a carotenoid.
摘要翻译：本发明提供了可用于治疗或预防焦虑症的高度安全的抗焦虑组合物。这种抗焦虑组合物包含类胡萝卜素作为活性成分。

2. 发明申请

US20220401377A1 COMPOSITION FOR PREVENTING AND/OR TREATING NEURODEGENERATIVE DISORDERS 有权
公开(公告)号：US20220401377A1
公开(公告)日：2022-12-22
申请号：US17772139
申请日：2020-10-20
申请人： Hideaki HARA , ICHIMARU PHARCOS CO., LTD.
发明人： Hideaki HARA , Masashi MIKAMI , Hiroyuki KOJIMA , Tatsuji TAKAHASHI , Kenichi ITO , Iddamalgoda ARUNASIRI
IPC分类号： A61K31/047 , A61K36/23 , A61K31/192 , A61P25/28
摘要： Provided is a composition useful for preventing and/or treating neurodegenerative disorders such as Alzheimer's disease and Parkinson's disease. The composition is for preventing and/or treating a neurodegenerative disorder, and contains, as an active ingredient, a compound represented by the following formula (I): or an isomer thereof, or a salt thereof.

3. 发明申请

US20120040994A1 THERAPEUTIC AGENT FOR GLAUCOMA COMPRISING Rho KINASE INHIBITOR AND PROSTAGLANDIN 审中-公开
标题翻译：包含Rho激酶抑制剂和前列腺素的GLAUCOMA治疗药物
公开(公告)号：US20120040994A1
公开(公告)日：2012-02-16
申请号：US13280684
申请日：2011-10-25
申请人： Tadashi NAKAJIMA , Takeshi MATSUGI , Hideaki HARA
发明人： Tadashi NAKAJIMA , Takeshi MATSUGI , Hideaki HARA
IPC分类号： A61K31/497 , A61P27/06 , A61K31/437
CPC分类号： A61K45/06 , A61K9/0048 , A61K31/437 , A61K31/4409 , A61K31/4725 , A61K31/5377 , A61K31/553 , A61K31/5575 , A61K2300/00
摘要： A therapeutic composition for treating glaucoma or for reducing intraocular pressure containing a combination of pharmaceutically effective amounts of drugs including (i) a Rho kinase inhibitor selected from the group consisting of (R)-(+)-N-(1H-pyrrolo[2,3-b]pyridin-4-yl)-4-(1-aminoethyl)benzamide and 1-(5-isoquinolinesulfonyl)-homopiperazine, or a salt thereof and (ii) a prostaglandin which is latanoprost or a salt of latanoprost, and (iii) optionally a pharmaceutically acceptable carrier. A therapeutic composition for treating glaucoma or for reducing intraocular pressure containing a combination of pharmaceutically effective amounts of drugs comprising (i) a Rho kinase which is (R)-(+)-N-(1H-pyrrolo[2,3-b]pyridin-4-yl)-4-(1-aminoethyl)benzamide or a slat thereof and (ii) a prostaglandin which is isopropyl unoprostone or a salt thereof, and (iii) optionally a pharmaceutically acceptable carrier.
摘要翻译：一种用于治疗青光眼或降低眼内压的治疗组合物，其包含药学有效量的药物的组合，包括（i）选自（R） - （+）-N-（1H-吡咯并[2 ，3-b]吡啶-4-基）-4-（1-氨基乙基）苯甲酰胺和1-（5-异喹啉磺酰基） - 高哌嗪或其盐和（ii）前列腺素，其为拉坦前列素或拉坦前列素盐，和（iii）任选的药学上可接受的载体。一种用于治疗青光眼或降低眼内压的治疗组合物，其包含药物有效量的药物的组合，其包含（i）Rho - （+） - N-（1H-吡咯并[2,3-b] 吡啶-4-基）-4-（1-氨基乙基）苯甲酰胺或其板条，和（ii）作为异丙基异佛石或其盐的前列腺素，和（iii）任选的药学上可接受的载体。

4. 发明申请

US20070163886A1 PROCESSING SOLUTION TANK 有权
标题翻译：加工溶液罐
公开(公告)号：US20070163886A1
公开(公告)日：2007-07-19
申请号：US11693018
申请日：2007-03-29
申请人： Hideaki HARA , Toshinori WATANABE
发明人： Hideaki HARA , Toshinori WATANABE
IPC分类号： C25D1/12
CPC分类号： C25D13/22
摘要： A processing solution tank of forming an agitating flow by flowing and circulating a processing solution in directions opposite to each other between the side of a liquid surface and the side of a tank bottom, in which a guide plate substantially of an arcuate shape is formed to an end of the tank situated at least to the downstream on the side of the liquid surface or the downstream on the side of the tank bottom in the agitating flow for reversing the flow downward to the tank bottom or upward to the liquid surface, and a swirl chamber having a swirl generating portion of a substantially arcuate face for capturing dusts is provided at the bottom of the tank, whereby high quality surface treatment, for example, electrodeposition coating can be conducted by uniformly stirring the processing solution so as not to cause backflow or turbulence in the processing solution tank while dipping a work on a conveyor in the processing solution.
摘要翻译： 1.一种处理液槽，其特征在于，在液面的侧面与罐底的侧面之间流动并循环处理液的方向形成搅拌流体，其中形成大致弓形的导向板，罐的端部至少位于搅拌流中的液面或罐底侧的下游侧的下游，用于将流向下方向下移动到罐底或向上流到液面，在罐的底部设置有具有用于捕获灰尘的大致弧形面的旋涡产生部的涡流室，由此可以通过均匀搅拌处理溶液来进行高质量的表面处理，例如电沉积涂覆，从而不会引起回流或处理溶液槽中的湍流，同时将工件浸入处理溶液中的输送机上。

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