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1. 发明申请

US20090258411A1 CENTRIFUGAL DEVICE AND METHOD FOR OVA DETECTION 审中-公开
标题翻译：用于OVA检测的离心装置和方法
公开(公告)号：US20090258411A1
公开(公告)日：2009-10-15
申请号：US12400364
申请日：2009-03-09
申请人： Henry Petithory , James Kelland , Kevin Sullivan , Linda Martin
发明人： Henry Petithory , James Kelland , Kevin Sullivan , Linda Martin
IPC分类号： C12N1/02 , C12M1/00
CPC分类号： B04B5/04 , A61B10/0038 , B01L3/0272 , B01L3/5021 , B01L3/5029 , B01L2300/0681 , B04B5/0414 , B04B7/02 , B04B11/04 , B04B11/06 , B04B2005/0464 , B04B2005/0478
摘要： A centrifugal device and method are provided for the separation of buoyant material such as parasitic ova from fecal matter. A rotor assembly, rotatable about its central axis in a centrifuge, includes a housing with a centrally located top opening leading to a centrally located mixing chamber. An annular sediment chamber is provided, also coaxial about the central axis, connected by a passage with the mixing chamber. A coring assembly is used to retrieve and insert a fecal sample into the mixing chamber for mixing with a flotation fluid. During centrifugation, heavier fecal components pass radially outwardly to the sediment chamber while the ova collect on the inward surface of the flotation fluid. After centrifugation, more flotation fluid is added, if needed, until a meniscus forms at the top opening. A coverslip is placed over the top opening and the ova float to the surface of the fluid and adhere to the coverslip. The coverslip is removed and the ova detected using standard microscopy procedures. In another aspect, a centrifugal device is provided in which the ova are delivered through centrifugation to a pipette tip for dispensing onto a microscope slide or coverslip.
摘要翻译：提供了一种离心装置和方法，用于将浮力物质（例如寄生虫卵）与粪便分离。在离心机中围绕其中心轴线旋转的转子组件包括具有中心定位的顶部开口的壳体，其通向位于中心的混合室。提供环形沉积室，其也围绕中心轴线共轴，通过与混合室的通道连接。取芯组件用于将粪便样品回收并插入到混合室中以与浮选流体混合。在离心过程中，较重的粪便部件径向向外通向沉淀室，而卵子则聚集在浮选流体的内表面上。离心后，如果需要，加入更多的浮选液，直到在顶部开口处形成弯液面。将盖玻片放置在顶部开口上方，并且ova浮动到流体表面并粘附到盖玻片上。取出盖玻片，使用标准显微镜检查检测到ova。在另一方面，提供一种离心装置，其中通过离心将卵子输送到移液管尖端以分配到显微镜载玻片或盖玻片上。

2. 发明授权

US08540082B2 Centrifugal assembly and method for ova detection 有权
标题翻译：离心装置及ova检测方法
公开(公告)号：US08540082B2
公开(公告)日：2013-09-24
申请号：US13120984
申请日：2009-09-25
申请人： James Kelland , Henry Petithory , Kevin Sullivan
发明人： James Kelland , Henry Petithory , Kevin Sullivan
IPC分类号： B04B5/02 , B04B7/00
CPC分类号： B01L3/50215 , A61B10/0038 , B01L2200/025 , B01L2300/0672 , B01L2300/0681 , B01L2300/0854 , B01L2400/0478 , B01L2400/0683
摘要： A centrifugal assembly is provided that can be used in common laboratory fixed angle or swinging bucket centrifuges for the separation of material, such as parasitic ova, based on particle density. The centrifugal assembly allows the fluid level to be gently adjusted to form a meniscus without disruption of the buoyant matter, such as ova. The centrifugal assembly also enables a user to easily and hygienically collect and transfer a measured amount of a sample, such as fecal material, and to break apart and mix the sample with a floatation fluid contained in a centrifuge tube.
摘要翻译：提供了一种离心组件，可用于普通的实验室固定角度或摆动式离心机中，用于基于颗粒密度分离材料，如寄生卵。离心组件允许轻轻地调整液面以形成弯月面而不破坏浮力物质，例如ova。离心组件还使得使用者能够容易且卫生地收集和转移测量量的诸如粪便材料的样品，并且将样品与包含在离心管中的浮选流体分开并混合。

3. 发明申请

US20110177931A1 CENTRIFUGAL ASSEMBLY AND METHOD FOR OVA DETECTION 有权
标题翻译：离心装配和OVA检测方法
公开(公告)号：US20110177931A1
公开(公告)日：2011-07-21
申请号：US13120984
申请日：2009-09-25
申请人： James Kelland , Henry Petithory , Kevin Sullivan
发明人： James Kelland , Henry Petithory , Kevin Sullivan
IPC分类号： B04B7/18
CPC分类号： B01L3/50215 , A61B10/0038 , B01L2200/025 , B01L2300/0672 , B01L2300/0681 , B01L2300/0854 , B01L2400/0478 , B01L2400/0683
摘要： A centrifugal assembly is provided that can be used in common laboratory fixed angle or swinging bucket centrifuges for the separation of material, such as parasitic ova, based on particle density. The centrifugal assembly allows the fluid level to be gently adjusted to form a meniscus without disruption of the buoyant matter, such as ova. The centrifugal assembly also enables a user to easily and hygienically collect and transfer a measured amount of a sample, such as fecal material, and to break apart and mix the sample with a floatation fluid contained in a centrifuge tube.
摘要翻译：提供了一种离心组件，可用于普通的实验室固定角度或摆动式离心机中，用于基于颗粒密度分离材料，如寄生卵。离心组件允许轻轻地调整液面以形成弯月面而不破坏浮力物质，例如ova。离心组件还使得使用者能够容易且卫生地收集和转移测量量的诸如粪便材料的样品，并且将样品与包含在离心管中的浮选流体分开并混合。

4. 发明申请

US20130048089A1 Analytical System For Performing Laboratory Protocols and Associated Methods 审中-公开
标题翻译：执行实验室协议和相关方法的分析系统
公开(公告)号：US20130048089A1
公开(公告)日：2013-02-28
申请号：US13695081
申请日：2011-04-29
申请人： Nils B. Adey , Rob Parry , James Kelland , Kevin Sullivan
发明人： Nils B. Adey , Rob Parry , James Kelland , Kevin Sullivan
IPC分类号： G01N1/28 , F17D1/00 , C40B40/00
摘要： Systems, devices, and methods for automating laboratory protocols utilizing cooperative efforts between differing components including fluidics, agitation and thermal control for processing a wide variety of disparate laboratory protocols are provided. In one aspect, a sample processing module is provided, including a housing configured to accommodate a pre-identified sample process, a temperature input capable of interfacing with a temperature controller, a fluid input capable of interfacing with an input fluid controller, a fluid output capable of interfacing with an output fluid controller, and a standardized agitation connector capable of interfacing with an agitator. A control system interfaces with the temperature input, fluid input, fluid output, and agitation connector to enable the system to perform laboratory protocols that require complex, sequential fluidic steps in association with the temperature and agitation control.
摘要翻译：提供了使用不同组件之间的协作努力自动化实验室协议的系统，设备和方法，包括用于处理各种不同实验室协议的流体学，搅拌和热控制。在一个方面，提供了一种样品处理模块，其包括被配置为容纳预先识别的样品过程的壳体，能够与温度控制器接口的温度输入，能够与输入流体控制器接口的流体输入，流体输出能够与输出流体控制器接口，以及能够与搅拌器接口的标准化搅拌连接器。控制系统与温度输入，流体输入，流体输出和搅拌连接器接口，使系统能够执行实验室协议，这些实验室协议需要与温度和搅拌控制相关联的复杂的，顺序的流程步骤。

5. 发明授权

US08841267B2 Micro-RNA scaffolds, non-naturally occurring micro-RNAs, and methods for optimizing non-naturally occurring micro-RNAs 有权
标题翻译：微RNA支架，非天然存在的微RNA，以及优化非天然存在的微RNA的方法
公开(公告)号：US08841267B2
公开(公告)日：2014-09-23
申请号：US12601506
申请日：2008-05-22
申请人： Melissa Kelley , Amanda Birmingham , Jon Karpilow , Anastasia Khvorova , Kevin Sullivan
发明人： Melissa Kelley , Amanda Birmingham , Jon Karpilow , Anastasia Khvorova , Kevin Sullivan
IPC分类号： C12N15/11 , C12N15/64 , C07H21/04
CPC分类号： C12N15/113 , C12N15/111 , C12N2310/141 , C12N2310/531 , C12N2320/30 , C12N2330/30 , C12Q1/6869
摘要： The present disclosure provides non-naturally occurring miR-196a-2 miRNAs and non-naturally occurring miR-204 miRNAs. The non-naturally occurring miRNAs of the disclosure have mature strand sequences distinct from their endogenous counterparts. The disclosure also provides methods of selecting mature strand sequences that function optimally in non-naturally occurring miR-196a-2 miRNAs. The methods and compositions of the disclosure may be used to mediate gene silencing via the RNAi pathway.
摘要翻译：本公开提供非天然存在的miR-196a-2 miRNA和非天然存在的miR-204 miRNA。本公开的非天然存在的miRNA具有与其内源对应物不同的成熟链序列。本公开还提供了选择在非天然存在的miR-196a-2 miRNA中最佳起作用的成熟链序列的方法。本公开的方法和组合物可用于通过RNAi途径介导基因沉默。

6. 发明申请

US20100026488A1 Safety barrier with integrated alarm 有权
标题翻译：集成报警器安全屏障
公开(公告)号：US20100026488A1
公开(公告)日：2010-02-04
申请号：US12221479
申请日：2008-08-04
申请人： Kevin Sullivan
发明人： Kevin Sullivan
IPC分类号： G08B13/00
CPC分类号： G08B21/086
摘要： A safety barrier with an integrated alarm comprising a plurality of posts for supporting fencing material, each post having an inner portion, an outer portion, an upper portion and a lower portion, wherein the lower portion of said post has embedded therein an alarm contact; a plurality of base supports for supporting posts, each base having an interior portion, an exterior portion, a top portion and a bottom portion, wherein the bottom of the interior portion of each base has an alarm contact embedded therein at the end proximate to the base support which corresponds to the alarm contact embedded in the lower portion of each post. The exterior portion of each base has an extension continuing downward from the bottom portion of each base for mounting in a ground surface or sleeve. The top portion of the base support contains an aperture having a diameter greater than the post. The bottom portion of the base is greater in diameter than the top portion thereof. Connecting alarm contacts embedded in the lower portion of the post and the bottom of the interior portion of the base closes the circuit between a transmitter and alarm contacts embedded in the lower portion of the post and the bottom of the interior portion of the base, which prevents the sound emitting device from emitting sound. Disconnecting alarm contacts embedded in the lower portion of the post and the bottom of the interior portion of the base opens a circuit, which causes a transmitter to send a signal to a receiver to trigger a sound emitting device to emit sound.
摘要翻译：一种具有集成警报器的安全屏障，包括用于支撑围栏材料的多个支柱，每个支柱具有内部部分，外部部分，上部分和下部分，其中所述支柱的下部嵌入有警报触点; 用于支撑柱的多个基座支撑件，每个基座具有内部部分，外部部分，顶部部分和底部部分，其中每个基座的内部部分的底部具有嵌入其中的报警接触件，基座支架对应于嵌入每个柱的下部的报警触点。每个基座的外部部分具有从每个底座的底部向下延伸的延伸部，用于安装在地面或套筒中。基部支撑件的顶部包含直径大于柱的孔。基部的底部的直径大于其顶部部分。连接埋在柱的下部和基座内部的底部的报警触点封闭了传感器和嵌入在柱的下部和底座内部的底部之间的报警触点之间的电路，防止发声装置发出声音。断开嵌入在柱的下部和底座内部的底部的报警触点打开电路，这使得发射器向接收器发送信号以触发发声装置发出声音。

7. 发明申请

US20070005497A1 Mutual Fund Card Method and System 有权
标题翻译：共同基金卡方式和制度
公开(公告)号：US20070005497A1
公开(公告)日：2007-01-04
申请号：US11461951
申请日：2006-08-02
申请人： Kevin Sullivan
发明人： Kevin Sullivan
IPC分类号： G06Q40/00
CPC分类号： G06Q30/02 , G06Q20/10 , G06Q20/105 , G06Q30/00 , G06Q40/00 , G06Q40/04
摘要： A computerized method and system for implementing such method, the method comprising establishing a card payment instrument account for an approved customer and an investment account for the benefit of the approved customer. A rebate is calculated periodically based on credit card usage and the rebate is applied to fund the investment account periodically. The rebate is the only funding of the investment account accomplished through the card payment instrument account.
摘要翻译：一种用于实现这种方法的计算机化方法和系统，所述方法包括为获得批准的客户的利益建立用于已批准客户的卡支付工具账户和投资账户。根据信用卡使用情况定期计算回扣，并定期回馈投资账户。退款是通过卡支付工具账户完成的投资账户的唯一资金。

8. 发明授权

US06917760B2 Wide passband optical interleaver 失效
标题翻译：宽通带光交错器
公开(公告)号：US06917760B2
公开(公告)日：2005-07-12
申请号：US10039242
申请日：2001-12-31
申请人： Yuan P. Li , Yan Wang , Robert John Shine, Jr. , Kevin Sullivan
发明人： Yuan P. Li , Yan Wang , Robert John Shine, Jr. , Kevin Sullivan
IPC分类号： G02B6/34 , H04J14/02 , H04B10/00
CPC分类号： H04J14/02 , G02B6/29361 , G02B6/29386
摘要： A method and apparatus is provided for reformatting or interleaving a WDM signal that includes a plurality of optical channels having a first bandwidth and a first channel spacing. The method begins by receiving the WDM signal and dividing it into first and second subsets of optical channels each having a second channel spacing. Next, the first subset of optical channels are divided into third and fourth subsets of optical channels each having a third channel spacing. In addition, the second subset of optical channels is divided into fifth and sixth subsets of optical channels each having a fourth channel spacing. The third and fifth subsets of optical channels are combined to generate a first output WDM signal, while the fourth and sixth subsets of optical channels are combined to generate a second output WDM signal.
摘要翻译：提供了一种用于重新格式化或交织包括具有第一带宽和第一信道间隔的多个光信道的WDM信号的方法和装置。该方法通过接收WDM信号并将其划分为每个具有第二信道间隔的光信道的第一和第二子集开始。接下来，光信道的第一子集被分成具有第三信道间隔的光信道的第三和第四子集。另外，光信道的第二子集被分成具有第四信道间隔的光信道的第五和第六子集。光信道的第三和第五子集被组合以产生第一输出WDM信号，而光信道的第四和第六子集被组合以产生第二输出WDM信号。

9. 发明授权

US06782157B1 Bidirectional optical interleaver 有权
标题翻译：双向光交织器
公开(公告)号：US06782157B1
公开(公告)日：2004-08-24
申请号：US10038882
申请日：2002-01-02
申请人： Huali Ariel Luo , Kevin Sullivan
发明人： Huali Ariel Luo , Kevin Sullivan
IPC分类号： G02B628
CPC分类号： G02B6/29386 , G02B6/29355 , H04J14/02
摘要： The abstract is amended to read, “An inventive method and apparatus is provided by a bidirectional optical 1×2 device formed by a cascade of three optical 2×2 devices. Each 2×2 device is bidirectional where optical signals propagate through the 2×2 device in the forward and backward directions simultaneously. The demultiplexing and multiplexing occur simultaneously to thereby perform bidirectional 1×2 optical demultiplexing and 2×1 optical multiplexing in the 1×2 device.”
摘要翻译：摘要被修改为：“本发明的方法和装置由由三个光学2x2装置的级联形成的双向光学1x2装置提供。每个2x2装置是双向的，其中光信号沿前后方向传播通过2x2装置同时进行解复用和多路复用，从而在1x2设备中执行双向1x2光解复用和2x1光复用。

10. 发明授权

US11847910B2 Emergency vehicle alert system 有权
公开(公告)号：US11847910B2
公开(公告)日：2023-12-19
申请号：US17244045
申请日：2021-04-29
申请人： Kevin Sullivan
发明人： Kevin Sullivan
IPC分类号： G08G1/087 , G08G1/01 , H04W4/90 , H04W4/44 , H04W4/80 , B60Q5/00
CPC分类号： G08G1/087 , B60Q5/00 , G08G1/0141 , H04W4/44 , H04W4/80 , H04W4/90
摘要： An emergency vehicle alert system includes a traffic control device having a transceiver. The transceiver is configured to receive a first signal and to transmit a second signal. A receiver is configured to receive the second signal from the transceiver and to initiate an alert upon receiving the second signal from the transceiver. The first signal is transmitted to the transceiver from an emergency vehicle and causes the traffic control device to transition from a first configuration to a second configuration. The transceiver transmits the second signal in response to the transceiver receiving the first signal.

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