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1. 发明授权

US08452416B2 Medical lead assembly and method for implantation thereof 有权
标题翻译：医用铅组件及其植入方法
公开(公告)号：US08452416B2
公开(公告)日：2013-05-28
申请号：US13000075
申请日：2008-06-27
申请人： Henrik Djurling , Rolf Hill , Olof Stegfeldt , Åsa Broomé , Hans Strandberg
发明人： Henrik Djurling , Rolf Hill , Olof Stegfeldt , Åsa Broomé , Hans Strandberg
IPC分类号： A61N1/05
CPC分类号： A61N1/05 , A61M25/0054 , A61M2025/0063 , A61N1/056 , A61N1/086 , A61N2001/0578
摘要： An assembly includes a medical implantable lead adapted to be attached with a distal end of the lead to an organ inside a human or animal body, the medical implantable lead being formed with an inner lumen extending along essentially the entire length of the lead. The assembly also includes a support core that has a desirable stiffness and a suitably cross sectional dimension such that it is insertable into the lumen (7) in order to increase the stiffness of the lead along its length during its working life when being implanted into a body. A method for implanting a medical implantable lead into a human or animal body makes use of such an assembly.
摘要翻译：组件包括医疗可植入引线，其适合于将引导件的远端连接到人体或动物体内的器官，所述医学可植入引线形成有沿着铅的整个长度的内腔延伸的内腔。组件还包括支撑芯，其具有期望的刚度和适当的横截面尺寸，使得其可插入到腔（7）中，以便在植入到内腔（7）的工作寿命期间增加引线沿其长度的刚度身体。将医用植入式铅植入人体或动物体内的方法利用了这种组件。

2. 发明申请

US20110093053A1 MEDICAL LEAD ASSEMBLY AND METHOD FOR IMPLANTATION THEREOF (As Amended) 有权
标题翻译：医疗铅组件及其植入方法（修改）
公开(公告)号：US20110093053A1
公开(公告)日：2011-04-21
申请号：US13000075
申请日：2008-06-27
申请人： Henrik Djurling , Rolf Hill , Olof Stegfeldt , Åsa Broomé , Hans Strandberg
发明人： Henrik Djurling , Rolf Hill , Olof Stegfeldt , Åsa Broomé , Hans Strandberg
IPC分类号： A61N1/00
CPC分类号： A61N1/05 , A61M25/0054 , A61M2025/0063 , A61N1/056 , A61N1/086 , A61N2001/0578
摘要： An assembly includes a medical implantable lead adapted to be attached with a distal end of the lead to an organ inside a human or animal body, the medical implantable lead being formed with an inner lumen extending along essentially the entire length of the lead. The assembly also includes a support core that has a desirable stiffness and a suitably cross sectional dimension such that it is insertable into the lumen in order to increase the stiffness of the lead along its length during its working life when being implanted into a body. A method for implanting a medical implantable lead into a human or animal body makes use of such an assembly.
摘要翻译：组件包括医疗可植入引线，其适合于将引导件的远端连接到人体或动物体内的器官，所述医学可植入引线形成有沿着铅的整个长度的内腔延伸的内腔。组件还包括支撑芯，其具有期望的刚度和适当的横截面尺寸，使得其可插入到内腔中，以便在植入体内时在其工作寿命期间沿其长度增加引线的刚度。将医用植入式铅植入人体或动物体内的方法利用了这种组件。

3. 发明申请

US20120022356A1 IMPLANTABLE MRI COMPATIBLE MEDICAL LEAD WITH A ROTATABLE CONTROL MEMBER 审中-公开
标题翻译：可植入MRI兼容医疗引导与可旋转的控制成员
公开(公告)号：US20120022356A1
公开(公告)日：2012-01-26
申请号：US13262179
申请日：2009-10-30
申请人： Linn Olsen , Mikael Forslund , Henrik Djurling , Patrik Forsström , Leda Henriquez , Kenneth Dahlberg , Olof Stegfeldt , Åke Sivard
发明人： Linn Olsen , Mikael Forslund , Henrik Djurling , Patrik Forsström , Leda Henriquez , Kenneth Dahlberg , Olof Stegfeldt , Åke Sivard
IPC分类号： A61N1/05 , A61B5/04
CPC分类号： A61N1/057 , A61N1/3752
摘要： A medical implantable lead is adapted to be implanted into a human or animal body for monitoring and/or controlling of an organ inside the body. The lead has in a distal end, a combined fixation means and electrode member in form of a helix, which is connected to a rotatable tubular member being connected to a rotatable member at a proximal end of the lead, and which is rotatable in relation to the lead and extendable out from the distal end, by rotation of the control member and the tubular torque transferring member, to be able to fixate the distal end of the lead to the organ by being screwed into the tissue. The helix is electrically connected to a connector at the proximal end by means of at least one electrically conducting wire formed as an electrically conducting coil, which is separate from the tubular torque transferring member and unrotatable in relation to the lead and that has one or more individual wires, each including an electrically conducting wire core and a surrounding electrically insulating layer, wherein the rotatable control member is rotatable within the connector.
摘要翻译：医用可植入引线适于植入人体或动物体内，用于监测和/或控制体内器官。引线具有远端，组合的固定装置和螺旋形式的电极构件，其连接到可旋转的管状构件，该可旋转的管状构件在引线的近端处连接到可旋转构件，并且其可相对于引线并且通过控制构件和管状扭矩传递构件的旋转从远端可伸出，以能够通过拧入组织而将引线的远端固定到器官。螺旋线通过至少一个形成为导电线圈的导电线电连接到近端处的连接器，导电线圈与管状扭矩传递构件分离并且相对于引线不可旋转，并且具有一个或多个各个电线各自包括导电线芯和周围的电绝缘层，其中可旋转控制构件可在连接器内旋转。

4. 发明授权

US08521307B2 Implantable MRI compatible medical lead 有权
标题翻译：可植入MRI兼容医用铅
公开(公告)号：US08521307B2
公开(公告)日：2013-08-27
申请号：US13262551
申请日：2009-07-10
申请人： Henrik Djurling , Kenneth Dahlberg , Mikael Forslund , Patrik Forsström , Leda Henriquez , Linn Olsen , Olof Stegfeldt , Åke Sivard
发明人： Henrik Djurling , Kenneth Dahlberg , Mikael Forslund , Patrik Forsström , Leda Henriquez , Linn Olsen , Olof Stegfeldt , Åke Sivard
IPC分类号： A61N1/05
CPC分类号： A61N1/057 , A61N1/3752
摘要： A medical implantable lead is adapted to be implanted into a human or animal body for monitoring and/or controlling of an organ inside the body, and has in a distal end, a combined fixation means and electrode member in form of a helix, which is rotatable in relation to the lead and extendable out from the distal end by rotation of a tubular torque transferring member. The helix is electrically connected to a connector in the proximal end by at least one electrically conducting wire, which is formed as an electrically conducting coil, which is separate from the tubular torque transferring member and that includes one or more individual wires each having an electrically conducting wire core and a surrounding electrically insulating layer. The tubular torque transferring member has no electrically conducting function to or from the helix. The lead is arranged such that the electrical connection between the helix and the conducting wire is always maintained regardless of the rotational position of the helix while no electrical connection is present between the helix and the tubular torque transferring member although the helix is rotatable by the tubular torque transferring member.
摘要翻译：医用可植入引线适于植入人体或动物体内，用于监测和/或控制体内器官，并且在远端具有组合的固定装置和螺旋形式的电极部件可相对于引线旋转，并通过管状扭矩传递构件的旋转从远端伸出。螺旋线通过至少一个导电线电连接到近端的连接器，导电线形成为导电线圈，其与管状扭矩传递构件分离，并且包括一个或多个单独的导线，每个导线导线芯和周围的电绝缘层。管状转矩传递部件不具有与螺旋之间的导电功能。导线被布置成使得螺旋和导线之间的电连接总是保持，而不管螺旋的旋转位置如何，同时螺旋和管状扭矩传递构件之间没有电连接，尽管螺旋可由管状扭矩传递构件。

5. 发明申请

US20120035693A1 IMPLANTABLE MRI COMPATIBLE MEDICAL LEAD 有权
标题翻译：可植入MRI兼容医用引线
公开(公告)号：US20120035693A1
公开(公告)日：2012-02-09
申请号：US13262551
申请日：2009-07-10
申请人： Henrik Djurling , Kenneth Dahlberg , Mikael Forslund , Patrik Forsström , Leda Henriquez , Linn Olsen , Olof Stegfeldt , Åke Sivard
发明人： Henrik Djurling , Kenneth Dahlberg , Mikael Forslund , Patrik Forsström , Leda Henriquez , Linn Olsen , Olof Stegfeldt , Åke Sivard
IPC分类号： A61N1/00
CPC分类号： A61N1/057 , A61N1/3752
摘要： A medical implantable lead is adapted to be implanted into a human or animal body for monitoring and/or controlling of an organ inside the body, and has in a distal end, a combined fixation means and electrode member in form of a helix, which is rotatable in relation to the lead and extendable out from the distal end by rotation of a tubular torque transferring member. The helix is electrically connected to a connector in the proximal end by at least one electrically conducting wire, which is formed as an electrically conducting coil, which is separate from the tubular torque transferring member and that includes one or more individual wires each having an electrically conducting wire core and a surrounding electrically insulating layer. The tubular torque transferring member has no electrically conducting function to or from the helix. The lead is arranged such that the electrical connection between the helix and the conducting wire is always maintained regardless of the rotational position of the helix while no electrical connection is present between the helix and the tubular torque transferring member although the helix is rotatable by the tubular torque transferring member.
摘要翻译：医用可植入引线适于植入人体或动物体内，用于监测和/或控制体内器官，并且在远端具有组合的固定装置和螺旋形式的电极部件可相对于引线旋转，并通过管状扭矩传递构件的旋转从远端伸出。螺旋线通过至少一个导电线电连接到近端的连接器，导电线形成为导电线圈，其与管状扭矩传递构件分离，并且包括一个或多个单独的导线，每个导线导线芯和周围的电绝缘层。管状转矩传递部件不具有与螺旋之间的导电功能。引线被布置成使得螺旋和导线之间的电连接总是保持，而不管螺旋的旋转位置如何，同时螺旋和管状扭矩传递构件之间没有电连接，尽管螺旋可由管状扭矩传递构件。

6. 发明授权

US08224457B2 Medical implantable lead 有权
标题翻译：医用植入式铅
公开(公告)号：US08224457B2
公开(公告)日：2012-07-17
申请号：US12447984
申请日：2006-10-31
申请人： Hans Strandberg , Anna Norlin-Weissenrieder , Leda Henriquez , Eva Harström , Mikael Sjögren , Annika Naeslund , Susanne Nilsson , Olof Stegfeldt
发明人： Hans Strandberg , Anna Norlin-Weissenrieder , Leda Henriquez , Eva Harström , Mikael Sjögren , Annika Naeslund , Susanne Nilsson , Olof Stegfeldt
IPC分类号： A61N1/05
CPC分类号： A61N1/05 , A61N1/056 , H01B7/0823
摘要： A medical implantable lead has a proximal end and a distal end, and a flexible flat elongate body. The elongate body includes a layer of strip conductors extending along the length of the flat elongate body, a top insulating layer, and a bottom insulating layer. The layer of strip conductors is sealingly enclosed between the top and bottom insulating layers, and at least a major portion of the flat elongate body is twisted into an elongate helical portion having a central cavity extending longitudinally of the helical portion.
摘要翻译：医用可植入引线具有近端和远端，以及柔性扁平细长体。细长主体包括沿扁平细长体的长度延伸的条形导体层，顶部绝缘层和底部绝缘层。带状导体层被密封地封闭在顶部和底部绝缘层之间，并且扁平细长体的至少大部分被扭转成具有沿螺旋部分纵向延伸的中心空腔的细长螺旋部分。

7. 发明申请

US20100114279A1 MEDICAL IMPLANTABLE LEAD 有权
标题翻译：医用植入式铅
公开(公告)号：US20100114279A1
公开(公告)日：2010-05-06
申请号：US12447984
申请日：2006-10-31
申请人： Hans Strandberg , Anna Norlin-Weissenrieder , Leda Henriquez , Eva Harström , Mikael Sjögren , Annika Naeslund , Susanne Nilsson , Olof Stegfeldt
发明人： Hans Strandberg , Anna Norlin-Weissenrieder , Leda Henriquez , Eva Harström , Mikael Sjögren , Annika Naeslund , Susanne Nilsson , Olof Stegfeldt
IPC分类号： A61N1/00
CPC分类号： A61N1/05 , A61N1/056 , H01B7/0823
摘要： A medical implantable lead has a proximal end and a distal end, and a flexible flat elongate body. The elongate body includes a layer of strip conductors extending along the length of the flat elongate body, a top insulating layer, and a bottom insulating layer. The layer of strip conductors is sealingly enclosed between the top and bottom insulating layers, and at least a major portion of the flat elongate body is twisted into an elongate helical portion having a central cavity extending longitudinally of the helical portion.
摘要翻译：医用可植入引线具有近端和远端，以及柔性扁平细长体。细长主体包括沿扁平细长体的长度延伸的条形导体层，顶部绝缘层和底部绝缘层。带状导体层被密封地封闭在顶部和底部绝缘层之间，并且扁平细长体的至少大部分被扭转成具有沿螺旋部分纵向延伸的中心空腔的细长螺旋部分。

8. 发明授权

US09108043B2 Bipolar screw-in lead 有权
标题翻译：双极螺丝引线
公开(公告)号：US09108043B2
公开(公告)日：2015-08-18
申请号：US12905911
申请日：2010-10-15
申请人： Mary Elizabeth Bush , Rolf Hill , Steven R. Conger , Olof Stegfeldt
发明人： Mary Elizabeth Bush , Rolf Hill , Steven R. Conger , Olof Stegfeldt
IPC分类号： A61N1/05
CPC分类号： A61N1/0573
摘要： An implantable active fixation lead includes an outer sheath, a protector member having a peripheral surface extending between its distal and proximal end surfaces with a helical groove formed in the peripheral surface, and a fixation helix integral with the outer sheath. The fixation helix includes a tip end engageable with body tissue and slidably engaged with the helical groove for relative translation and rotation. A longitudinal force on the lead firmly engages the protector member's distal end surface with the body tissue. With the fixation helix initially retracted proximally of the protector member's distal end surface and disengaged from the body tissue, upon application of torque to the outer sheath, the distal end surface of the protector member is moved proximally with respect to the fixation helix which, simultaneously, is extended distally beyond the distal end surface of the protector member to an extended position into engagement with the body tissue.
摘要翻译：可植入主动固定引线包括外护套，保护构件，其具有在其远端表面和近端表面之间延伸的周边表面，在外周表面上形成有螺旋槽，以及与外护套成一体的固定螺旋。固定螺旋包括可与身体组织接合并且与螺旋槽可滑动地接合以用于相对平移和旋转的尖端。导线上的纵向力使保护构件的远端表面与身体组织牢固地接合。当固定螺旋件最初在保护器构件的远端表面的近侧收回并且从身体组织脱离时，当向外护套施加扭矩时，保护构件的远端表面相对于固定螺旋线向近侧移动，同时远离保护器构件的远端表面延伸到与身体组织接合的延伸位置。

9. 发明授权

US09114251B2 Medical implantable lead and a method for attaching the same 有权
标题翻译：医用可植入引线及其附着方法
公开(公告)号：US09114251B2
公开(公告)日：2015-08-25
申请号：US12596607
申请日：2008-04-25
申请人： Rolf Hill , Olof Stegfeldt
发明人： Rolf Hill , Olof Stegfeldt
IPC分类号： A61N1/04 , A61N1/05
CPC分类号： A61N1/0573
摘要： A medical implantable lead of the type being adapted to be implanted into a human or animal body and attached with a distal end to an organ inside the body, has a helix of a helical wire in the distal end which is adapted to be screwed into the organ. In addition to the first helix, the lead also has a second helix of a helical wire, the second helix having the same diameter, the same pitch and being intertwined with the helical wire of the first helix and which, upon rotation of the first helix, will be rotated and screwed into the tissue. The first helix is electrically non-conductive whereas the second helix is electrically conductive. In a method for attaching a medical implantable lead to an organ inside a human or animal body, such a medical lead is employed and fixed to tissue in vivo.
摘要翻译：该类型的医用可植入引线适于被植入到人或动物体中并且与远端连接到身体内部的器官，具有在远端中的螺旋线的螺旋，其适于拧入器官。除了第一螺旋之外，引线还具有螺旋线的第二螺旋，第二螺旋具有相同的直径，相同的间距并与第一螺旋的螺旋线缠结，并且在第一螺旋旋转时，将旋转并拧入组织。第一螺旋是非导电的，而第二螺旋是导电的。在用于将医用可植入引线附着到人或动物体内的器官的方法中，使用这种医用引线并在体内固定到组织。

10. 发明申请

US20130156933A1 METHOD FOR MANUFACTURING AN ACTIVE FIXATION ELECTRODE 审中-公开
标题翻译：制造活性固定电极的方法
公开(公告)号：US20130156933A1
公开(公告)日：2013-06-20
申请号：US13549087
申请日：2012-07-13
申请人： Anna Norlin Weissenrieder , Rolf Hill , Olof Stegfeldt , Marie Herstedt , Mikael Forslund , Susanne Nilsson
发明人： Anna Norlin Weissenrieder , Rolf Hill , Olof Stegfeldt , Marie Herstedt , Mikael Forslund , Susanne Nilsson
IPC分类号： H01B13/00
CPC分类号： H01B13/00 , A61N1/0573 , Y10T29/49073 , Y10T29/49124 , Y10T29/49169 , Y10T29/49174 , Y10T29/49201 , Y10T29/49218
摘要： The present invention relates to methods for manufacturing active fixation helices for the stimulation and/or sensing of organs. A first embodiment of a method in accordance with the present invention for making a helix comprises a first step of producing an elongated helix precursor body comprising one or more electrical conductors surrounded by an insulating material. This helix precursor body is then shaped into a helix, material removed in predetermined places in order to expose the areas of the conductors which will be used as electrodes in the final product. The body is coated with an electrically conducting biocompatible coating which is subsequently partly removed in continuous loops from around the electrodes in order to electrically insulate them from each other and to ensure that the electrically active areas of the electrodes are of the correct dimensions.
摘要翻译：本发明涉及用于制造用于刺激和/或感测器官的活动固定螺旋的方法。根据本发明的用于制造螺旋的方法的第一实施例包括制造细长螺旋前体体的第一步骤，该主体包括由绝缘材料包围的一个或多个电导体。然后将该螺旋前体体成形为螺旋，在预定位置移除材料，以暴露将用作最终产品中的电极的导体区域。该主体涂覆有导电生物相容性涂层，其随后部分地从电极周围以连续的环路去除，以使它们彼此电绝缘并且确保电极的电活性区域具有正确的尺寸。

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