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    • 1. 发明授权
    • Halomethyl-thioamino-benzamides, a process for their preparation and
their use
    • 卤甲基 - 硫代氨基 - 苯甲酰胺,其制备方法及其应用
    • US4455309A
    • 1984-06-19
    • US294694
    • 1981-08-20
    • Helmut RitterWilfried PaulusEngelbert KuhleHermann Genth
    • Helmut RitterWilfried PaulusEngelbert KuhleHermann Genth
    • A01N47/04C07C67/00C07C313/00C07C313/20C07D295/192A61K31/495A01N47/08C07D241/04
    • C07D295/192A01N47/04
    • New halo-methyl-thioamino-benzamides of the formula ##STR1## wherein X.sup.1 represents optionally substituted alkylene, arylene or alkarylene, it being possible for the alkylene and/or arylene and/or alkarylene groups to be linked via oxo, thio, carboxo, carboxamido or sulphoxo groups,A.sup.1 denotes the radical ##STR2## wherein Hal represents halogen,the various substituents R can be identical or different and represent hydrogen, optionally substituted alkyl or aryl or a substituted R, in the case where X.sup.1 denotes optionally substituted ethylene and m.sup.1 and n.sup.1 represent the number 1, forms an ethylene bridge by being linked to a second R,m.sup.1 denotes an integer from 1 to 5 and indicates the number of linkages of ##STR3## with X.sup.1, and n.sup.1 denotes a number from 1 to 100;a process for preparing the same by reaction of a halo-methyl-thioamino-benzoic acid fluoride with an amine in the presence of a base and the use of such halo-methyl-thioamino-benzamides as microbicidal agents.
    • 其中X 1表示任选取代的亚烷基,亚芳基或亚烷基的新的卤代甲基 - 硫代氨基 - 苯甲酰胺,亚烷基和/或亚芳基和/或亚烷基可以通过氧代,硫代,羧基, 甲酰胺基或亚磺基,A1表示基团,其中Hal表示卤素,各个取代基R可以相同或不同,表示氢,任选取代的烷基或芳基或取代的R,在X1表示任选取代的亚乙基和 m1和n1表示数字1,通过连接到第二个R形成乙烯桥,m1表示1至5的整数,表示与X1的连接数,n1表示1至100的数字 ; 在碱的存在下,通过卤代 - 甲基 - 硫代氨基 - 苯甲酸氟化物与胺的反应以及使用这种卤代 - 甲基 - 硫代氨基 - 苯甲酰胺作为杀菌剂来制备该方法。
    • 6. 发明申请
    • DENTAL COMPOSITION
    • 牙科成分
    • US20120238662A1
    • 2012-09-20
    • US13512769
    • 2010-12-07
    • Joachim E. KleeHelmut RitterSven PohleOliver ElsnerMareike Bardts
    • Joachim E. KleeHelmut RitterSven PohleOliver ElsnerMareike Bardts
    • C08G63/91A61K6/00
    • A61K6/0835A61K6/0038A61K6/083C08F218/06C08F265/02C08F267/04C08L33/00
    • Dental cement composition comprising a polymerizable polyacidic polymer having repeating units in the polymer backbone, which are represented by the following formula (I)1 (II), and/or (III): wherein X represents O, S, or NR′, whereby R′ represents a hydrogen atom or a straight or branched C1-C6 alkyl group, C3-C6 cycloalkyl group, or C4-C8 cycloalkylalkyl group, Y a group of the following formula (IV), wherein each of L1, L2, L3 and L4, which are independent from each other represents a single bond, a straight or branched C1-C6 alkylene group, a straight or branched C1-C6 alkenylene, or a straight or branched C1-C20 alkylene group which includes 1 to 8 atoms selected from oxygen and sulfur atoms, X′ represents O, S, or NR″, whereby R″ represents a hydrogen atom or a straight or branched C1-C6 alkyl group, C3-C6 cycloalkyl group, or C4-C8 cycloalkylalkyl group, m is 0 to 3, and n is 1 to 3.
    • 含有聚合物主链中具有重复单元的聚合性聚酸聚合物的牙科水泥组合物,其由下式(I)1(II)和/或(III)表示:其中X表示O,S或NR',由此 R'表示氢原子或直链或支链C1-C6烷基,C3-C6环烷基或C4-C8环烷基烷基,Y为下式(Ⅳ)的基团,其中L1,L2,L3和 L4彼此独立地表示单键,直链或支链C1-C6亚烷基,直链或支链C1-C6亚烯基或包含1至8个选自以下的1至8个原子的直链或支链C 1 -C 20亚烷基 氧原子和硫原子,X'表示O,S或NR“,其中R”表示氢原子或直链或支链C 1 -C 6烷基,C 3 -C 6环烷基或C 4 -C 8环烷基烷基,m为0 至3,n为1至3。