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    • 4. 发明申请
    • ALGORITHMS FOR OUTCOME PREDICTION IN PATIENTS WITH NODE-POSITIVE CHEMOTHERAPY-TREATED BREAST CANCER
    • 患有结直肠癌治疗乳腺癌的患者的预后预测方法
    • US20110166838A1
    • 2011-07-07
    • US12999522
    • 2009-06-16
    • Mathias GehrmannRalf KronenwettUdo StroppChristian Von TörneKarsten Weber
    • Mathias GehrmannRalf KronenwettUdo StroppChristian Von TörneKarsten Weber
    • G06F7/60
    • C12Q1/6886C12Q2600/106C12Q2600/112C12Q2600/118C12Q2600/136C12Q2600/158G16B20/00G16B25/00G16B40/00
    • The invention relates to methods for predicting an outcome of cancer in a patient suffering from cancer, said patient having been previously diagnosed as node positive and treated with cytotoxic chemotherapy, said method comprising determining in a biological sample from said patient an expression level of a plurality of genes selected from the group consisting of ACTG1, CAl2, CALM2, CCND1, CHPT1, CLEC2B, CTSB, CXCL13, DCN, DHRS2, EIF4B, ERBB2, ESR1, FBXO28, GABRP, GAPDH, H2AFZ, IGFBP3, IGHG1, IGKC, KCTD3, KIAA0101, KRT17, MLPH, MMP1, NAT1, NEK2, NR2F2, OAZ1, PCNA, PDLIM5, PGR, PPIA, PRC1, RACGAP1, RPL37A, SOX4, TOP2A, UBE2C and VEGF; ABCB1, ABCG2, ADAM15, AKR1C1, AKR1C3, AKT1, BANF1, BCL2, BIRC5, BRMS1, CASP10, CCNE2, CENPJ, CHPT1, EGFR, CTTN, ERBB3, ERBB4, FBLN1, FIP1L1, FLT1, FLT4, FNTA, GATA3, GSTP1, Herstatin, IGF1R, IGHM, KDR, KIT, CKRT5, SLC39A6, MAPK3, MAPT, MKI67, MMP7, MTA1, FRAP1, MUC1, MYC, NCOA3, NFIB, OLFM1, TP53, PCNA, PI3K, PPERLD1, RAB31, RAD54B, RAF1, SCUBE2, STAU, TINF2, TMSL8, VGLL1, TRA@, TUBA1, TUBB, TUBB2A.
    • 本发明涉及用于预测患有癌症的患者的癌症结果的方法,所述患者先前被诊断为淋巴结阳性并用细胞毒性化疗治疗,所述方法包括在来自所述患者的生物样品中确定多个表达水平 选自ACTG1,CA2,CALM2,CCND1,CHPT1,CLEC2B,CTSB,CXCL13,DCN,DHRS2,EIF4B,ERBB2,ESR1,FBXO28,GABRP,GAPDH,H2AFZ,IGFBP3,IGHG1,IGKC,KCTD3, KIAA0101,KRT17,MLPH,MMP1,NAT1,NEK2,NR2F2,OAZ1,PCNA,PDLIM5,PGR,PPIA,PRC1,RACGAP1,RPL37A,SOX4,TOP2A,UBE2C和VEGF; ABCB1,ABCG2,ADAM15,AKR1C1,AKR1C3,AKT1,BANF1,BCL2,BIRC5,BRMS1,CASP10,CCNE2,CENPJ,CHPT1,EGFR,CTTN,ERBB3,ERBB4,FBLN1,FIP1L1,FLT1,FLT4,FNTA,GATA3,GSTP1, Herbatin,IGF1R,IGHM,KDR,KIT,CKRT5,SLC39A6,MAPK3,MAPT,MKI67,MMP7,MTA1,FRAP1,MUC1,MYC,NCOA3,NFIB,OLFM1,TP53,PCNA,PI3K,PPERLD1,RAB31,RAD54B,RAF1, SCUBE2,STAU,TINF2,TMSL8,VGLL1,TRA @,TUBA1,TUBB,TUBB2A。
    • 5. 发明申请
    • AIR SPRING FOR A VEHICLE
    • 空中弹簧车
    • US20100001444A1
    • 2010-01-07
    • US12374583
    • 2007-08-07
    • Karsten Weber
    • Karsten Weber
    • F16F9/05
    • B60G11/27B60G7/04B60G2202/152B60G2204/45B60G2204/4502F16F9/052F16F9/057
    • An air spring for a vehicle comprises an air bellows that includes an axle-side region and a superstructure-side region movable with respect to one other between a first, adjacent position and a second, spaced-apart position, and a plunger which is arranged on the axle-side region of the air bellows. The air spring further comprising a fastening section adapted to fasten the superstructure-side region of the air bellows to a support element of the vehicle, and a displacement element which is arranged on the fastening section of the air bellows, wherein the displacement element fills at least a substantial portion of the space between the plunger and the fastening section in the first position of the air bellows.
    • 一种用于车辆的空气弹簧包括空气波纹管,其包括轴侧区域和在第一相邻位置和第二间隔位置之间可相对于彼此移动的上部结构侧区域,以及布置成 在空气波纹管的轴侧区域。 空气弹簧还包括紧固部分,其适于将空气波纹管的上部结构侧区域紧固到车辆的支撑元件;以及位移元件,其布置在空气波纹管的紧固部分上,其中位移元件填充在 在空气波纹管的第一位置的柱塞和紧固部分之间的空间的至少大部分。
    • 7. 发明申请
    • EXPANDABLE SHAFT
    • 可膨胀的轴
    • US20120018565A1
    • 2012-01-26
    • US13143820
    • 2009-10-23
    • Karsten Weber
    • Karsten Weber
    • B65H75/24
    • B65H75/243
    • The present invention relates to an expandable shaft (1) for insertion into a core, the expandable shaft have a longitudinal extension and comprising: a profile (4), which extends in the longitudinal direction of the shaft, the profile comprising a plurality of longitudinal grooves; inflatable and expandable chambers which are adapted to be arranged in the grooves; gripping means (3) which are arranged in connection to the expandable chambers, the gripping means being adapted to radial movement between a first position and a second position in view of an expansion of the inflatable and expandable chambers so that the gripping means (3) are movable in a radial direction between a first position and a second position depending on an expansion of the expandable chambers wherein an outer cylindrical tube is arranged outside the profile (4), the outer cylindrical tube comprising a plurality of openings, and wherein the gripping means (3) are aligned with the openings of the tube so that the gripping means can project through and beyond the tube in a radial direction of the shaft during the expansion of the expandable chambers.
    • 本发明涉及一种用于插入到芯中的可膨胀轴(1),该可膨胀轴具有一纵向延伸部分,并包括:一个在轴的纵向延伸的型材(4),该型材包括多个纵向 凹槽 适于布置在凹槽中的充气和可膨胀室; 夹持装置(3),其布置成与可膨胀腔室相连接,所述夹持装置适于在可膨胀和可膨胀腔室的膨胀的情况下考虑到第一位置和第二位置之间的径向移动,使得夹持装置(3) 可根据可膨胀室的膨胀在第一位置和第二位置之间沿径向方向移动,其中外圆柱形管布置在型材(4)的外侧,外圆柱形管包括多个开口,并且其中夹紧 装置(3)与管的开口对准,使得夹持装置可以在可膨胀室的膨胀期间沿着轴的径向突出并超过管。
    • 9. 发明授权
    • Clamp
    • US5546640A
    • 1996-08-20
    • US302811
    • 1994-09-13
    • Karlhans KronauerJosef AignerFranz KleinKarsten WeberMonika SchmidRobert Pfab
    • Karlhans KronauerJosef AignerFranz KleinKarsten WeberMonika SchmidRobert Pfab
    • F16B2/20A47G25/48D06F55/00D06F57/00A44B21/00
    • A47G25/485Y10T24/44376Y10T24/4447Y10T24/44521
    • A clamp for arrangement on a carrying arm is described. The clamp has a first and a second clamp half (10, 20) with in each case two lateral angle pieces (12; 21 ), in which are located a hole (14; 23) for positioning the clamp halves (10, 20) on the carrying arm, whereby the angle pieces (12, 21) which are directed against each other lie pairwise against each other and in each case one angle piece (21) of each clamp half (10, 20) lies on the inside and the other angle piece (12) of the same clamp half (10, 20) lies on the outside, and a legged spring (4) which lies between the clamp halves (10, 20) and keeps the clamps (3) closed. The internal angle piece (21) of one clamp half (10; 20) interlocks rotatably with the external angle piece (12) of the other clamp half (20; 10), and the legged spring (4) fills, in axial direction, the space between the internal angle pieces (21) in each case of the clamp halves (10, 20).
    • PCT No.PCT / EP94 / 00099 Sec。 371日期1994年9月13日 102(e)1994年9月13日PCT 1994年1月14日PCT PCT。 出版物WO94 / 15506 日期:1994年7月21日描述了用于在承载臂上布置的夹具。 夹具具有第一和第二夹具半部(10,20),每个壳体中分别具有两个横向角件(12; 21),其中定位有用于定位夹具半部(10,20)的孔(14; 23) 由此,彼此相对的角部件(12,21)彼此成对配置,并且在每种情况下,每个夹具半部(10,20)的一个角件(21)位于内侧,并且 相同的夹具半部(10,20)的其他角件(12)位于外侧,并且位于夹具半部(10,20)之间并保持夹具(3)关闭的有腿弹簧(4)。 一个夹具半部(10; 20)的内角件(21)与另一个夹具半部(20; 10)的外角件(12)可转动地连接,并且有腿的弹簧(4)沿轴向方向填充, 每个夹具半部(10,20)的内角片(21)之间的空间。