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1. 发明授权

US08092521B2 Device for the implantation and fixation of prosthetic valves 有权
标题翻译：假体瓣植入和固定装置
公开(公告)号：US08092521B2
公开(公告)日：2012-01-10
申请号：US11589570
申请日：2006-10-30
申请人： Hans-Reiner Figulla , Markus Ferrari , Christoph Damm
发明人： Hans-Reiner Figulla , Markus Ferrari , Christoph Damm
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/24 , A61F2/2409 , A61F2/2412 , A61F2/2427 , A61F2/243 , A61F2/2433 , A61F2/2436 , A61F2/82 , A61F2/95 , A61F2/958 , A61F2002/9528 , A61F2210/0014 , A61F2220/0025 , A61F2230/0054 , A61F2250/006
摘要： A device for the transvascular implantation and fixation of prosthetic heart valves having a self-expanding heart valve stent (10) with a prosthetic heart valve (11) at its proximal end is introducible into a patient's main artery. With the objective of optimizing such a device to the extent that the prosthetic heart valve (11) can be implanted into a patient in a minimally-invasive procedure, to ensure optimal positioning accuracy of the prosthesis (11) in the patient's ventricle, the device includes a self-expanding positioning stent (20) introducible into an aortic valve positioned within a patient. The positioning stent is configured separately from the heart valve stent (10) so that the two stents respectively interact in their expanded states such that the heart valve stent (10) is held by the positioning stent (20) in a position in the patient's aorta relative the heart valve predefinable by the positioning stent (20).
摘要翻译：用于在其近端具有具有假心脏瓣膜（11）的自扩张型心脏瓣膜支架（10）的假性心脏瓣膜的经血管植入和固定的装置可导入患者的主动脉。为了将这种装置优化到可以以微创程序将假体心脏瓣膜（11）植入患者体内的程度，为了确保患者心室中假体（11）的最佳定位精度，该装置包括可扩张到定位在患者体内的主动脉瓣的自扩张定位支架（20）。所述定位支架与所述心脏瓣膜支架（10）分开配置，使得所述两个支架分别以其展开状态相互作用，使得所述心脏瓣膜支架（10）由所述定位支架（20）保持在患者主动脉中的位置相对于由定位支架（20）预先确定的心脏瓣膜。

2. 发明授权

US07914575B2 Medical device for treating a heart valve insufficiency 有权
公开(公告)号：US07914575B2
公开(公告)日：2011-03-29
申请号：US12572340
申请日：2009-10-02
申请人： Volker Guyenot , Thomas Peschel , Christoph Damm , Hans-Reiner Figulla , Markus Ferrari , Johannes Jung
发明人： Volker Guyenot , Thomas Peschel , Christoph Damm , Hans-Reiner Figulla , Markus Ferrari , Johannes Jung
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/2442 , A61F2210/0014 , A61F2220/0008 , A61F2220/0016 , A61F2220/0075 , A61F2230/0013 , A61F2230/0054 , Y10T29/5116
摘要： A medical device for treating a heart valve insufficiency, with an endoprosthesis which can be introduced into a patient's body and expanded to secure a heart valve prosthesis in the patient's aorta. In an embodiment, the endoprosthesis has at plurality of positioning arches configured to be positioned with respect to a patient's aorta and a plurality of retaining arches to support a heart valve prosthesis. The endoprosthesis includes a first collapsed mode during the process of introducing it into the patient's body and a second expanded mode when it is implanted.

3. 发明授权

US07896913B2 Anchoring system for implantable heart valve prostheses 有权
标题翻译：植入式心脏瓣膜假体锚固系统
公开(公告)号：US07896913B2
公开(公告)日：2011-03-01
申请号：US11515589
申请日：2006-09-05
申请人： Christoph Damm , Carsten Weber , Stefan Risse , Volker Guyenot , Matthias Mohaupt , Gerd Harnisch , Peggy Dorrer , Markus Ferrari , Klaus Lang , Hans-Reiner Figulla
发明人： Christoph Damm , Carsten Weber , Stefan Risse , Volker Guyenot , Matthias Mohaupt , Gerd Harnisch , Peggy Dorrer , Markus Ferrari , Klaus Lang , Hans-Reiner Figulla
IPC分类号： A61F2/06 , A61F2/24
CPC分类号： A61F2/2418 , A61F2220/0008 , A61F2220/0016
摘要： The invention relates to an anchoring system for heart valve prostheses which can be implanted by introduction via the aorta without any major surgical operation. With the heart valve prosthesis according to the invention it shall be achieved that this can be safely and quickly guided through the aorta toward the heart, and can be fixed there. With this, hook-shaped elements are secured to the commissures of the heart valve prosthesis the hooks of which are guided in an outward direction through the heart valve prosthesis material.
摘要翻译：本发明涉及一种用于心脏瓣膜假体的锚固系统，其可以通过主动脉的引入而植入，而无需任何大的手术操作。对于根据本发明的心脏瓣膜假体，应当实现这可以安全和快速地通过主动脉引导到心脏，并且可以固定在那里。由此，钩形元件被固定到心脏瓣膜假体的连合处，其钩被沿向外的方向引导通过心脏瓣膜假体材料。

4. 发明申请

US20090234443A1 Catheter for the Transvascular Implantation of Prosthetic Heart Valves 有权
标题翻译：人造心脏瓣膜血管植入导管
公开(公告)号：US20090234443A1
公开(公告)日：2009-09-17
申请号：US11795590
申请日：2006-01-12
申请人： Rüdiger Ottma , Robert Moszner , Hans-Reiner Figulla , Markus Ferrari , Christoph Damm
发明人： Rüdiger Ottma , Robert Moszner , Hans-Reiner Figulla , Markus Ferrari , Christoph Damm
IPC分类号： A61F2/24 , A61F2/06
CPC分类号： A61F2/2427 , A61F2/2418 , A61F2/2436 , A61F2002/9517 , A61F2240/008
摘要： The invention relates to a catheter for the transvascular implantation of prosthetic heart valves, in particular comprising self-expanding anchorage supports (10), which allow a minimally invasive implantation of prosthetic heart valves. The aim of the invention is to reduce the risk to the patient during the implantation. To achieve this, according to the invention a prosthetic heart valve comprising anchorage supports is temporarily housed in a folded form in a cartridge-type unit (4) during the implantation. The cartridge-type unit can be fixed on the proximal end of a guide system (1), which comprises a flexible region (9) that can be guided through the aorta. Actuating elements (2, 3) run through the interior of the hollow guide system, said elements permitting sections of the cartridge-type unit to be displaced radially about their longitudinal axis and/or laterally in a proximal direction, thus allowing individual sections of the anchorage support and the associated prosthetic heart valve to be sequentially released.
摘要翻译：本发明涉及一种用于假体心脏瓣膜的经血管植入的导管，特别地包括允许假体心脏瓣膜的微创植入的自膨胀锚固支撑件（10）。本发明的目的是降低在植入期间患者的风险。为了实现这一点，根据本发明，在植入期间，包括锚固支撑件的假体心脏瓣膜在植入期间以折叠形式暂时容纳在盒式单元（4）中。药筒型单元可以固定在引导系统（1）的近端上，引导系统（1）包括可以被引导通过主动脉的柔性区域（9）。致动元件（2,3）穿过中空导向系统的内部，所述元件允许盒式单元的部分围绕其纵向轴线径向偏移和/或在近端方向上横向移动，从而允许锚固支撑件和相关联的假体心脏瓣膜被顺序释放。

5. 发明申请

US20080255660A1 Medical device for treating a heart valve insufficiency 有权
标题翻译：用于治疗心脏瓣膜不全的医疗装置
公开(公告)号：US20080255660A1
公开(公告)日：2008-10-16
申请号：US11785072
申请日：2007-04-13
申请人： Volker Guyenot , Thomas Peschel , Christoph Damm , Hans-Reiner Figulla , Markus Ferrari , Johannes Jung
发明人： Volker Guyenot , Thomas Peschel , Christoph Damm , Hans-Reiner Figulla , Markus Ferrari , Johannes Jung
IPC分类号： A61F2/24 , B21D53/00
CPC分类号： A61F2/2418 , A61F2/2442 , A61F2210/0014 , A61F2220/0008 , A61F2220/0016 , A61F2220/0075 , A61F2230/0013 , A61F2230/0054 , Y10T29/5116
摘要： A medical device for treating a heart valve insufficiency, with an endoprosthesis which can be introduced into a patient's body and expanded to secure a heart valve prosthesis in the patient's aorta. In an embodiment, the endoprosthesis has at plurality of positioning arches configured to be positioned with respect to a patient's aorta and a plurality of retaining arches to support a heart valve prosthesis. The endoprosthesis includes a first collapsed mode during the process of introducing it into the patient's body and a second expanded mode when it is implanted.
摘要翻译：用于治疗心脏瓣膜不全的医疗装置，其具有可被引入患者体内并扩张以将患者主动脉中的心脏瓣膜假体固定的内假体。在一个实施例中，内假体具有多个定位弓，其构造成相对于患者主动脉定位并且具有多个保持弓以支撑心脏瓣膜假体。内置假体包括在将其插入患者体内的过程中的第一折叠模式，以及植入时的第二扩张模式。

6. 再颁专利

USRE45130E1 Device for fastening and anchoring cardiac valve prostheses 有权
标题翻译：用于紧固和固定心脏瓣膜假体的装置
公开(公告)号：USRE45130E1
公开(公告)日：2014-09-09
申请号：US12213991
申请日：2008-06-26
申请人： Hans-Reiner Figulla , Markus Ferrari , Carsten Weber , Thomas Peschel , Christoph Damm
发明人： Hans-Reiner Figulla , Markus Ferrari , Carsten Weber , Thomas Peschel , Christoph Damm
IPC分类号： A61F2/24 , A61F2/06
摘要： This invention relates to a device for fastening and anchoring heart valve prostheses which is essentially formed of wire-shaped interconnected elements. The aim of the invention is to be able to be implant, in a minimally invasive manner, a device of this type via the aorta by compressing the device to make it smaller, and by extending the same at the site of implantation, whereby ensuring a secure retention and a secure sealing with regard to the aorta wall. To this end, the invention provides that for fastening and supporting a cardiac valve prosthesis, three identical pairs of arched elements are interconnected, with a configuration that is offset by 120°, by means of solid body articulations. These solid body articulations carry out the function of pivot bearings.
摘要翻译：本发明涉及一种用于紧固和锚定心脏瓣膜假体的装置，其基本上由线状互连元件形成。本发明的目的是能够以微创的方式通过压缩该装置以使其更小并通过在植入部位延伸而将该装置以微创方式植入到主动脉中，从而确保保持固定和对主动脉壁的安全密封。为此，本发明提供了用于紧固和支撑心脏瓣膜假体的三个相同的拱形元件对，通过固体关节连接，其构造被偏移120°。这些实心铰接件具有枢轴轴承的功能。

7. 发明授权

US08685085B2 Medical device for treating a heart valve insufficiency 有权
标题翻译：用于治疗心脏瓣膜不全的医疗装置
公开(公告)号：US08685085B2
公开(公告)日：2014-04-01
申请号：US13030708
申请日：2011-02-18
申请人： Volker Guyenot , Thomas Peschel , Christoph Damm , Hans-Reiner Figulla , Markus Ferrari , Johannes Jung
发明人： Volker Guyenot , Thomas Peschel , Christoph Damm , Hans-Reiner Figulla , Markus Ferrari , Johannes Jung
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/2442 , A61F2210/0014 , A61F2220/0008 , A61F2220/0016 , A61F2220/0075 , A61F2230/0013 , A61F2230/0054 , Y10T29/5116
摘要： A medical device for treating a heart valve insufficiency, with an endoprosthesis which can be introduced into a patient's body and expanded to secure a heart valve prosthesis in the patient's aorta. In an embodiment, the endoprosthesis has at plurality of positioning arches configured to be positioned with respect to a patient's aorta and a plurality of retaining arches to support a heart valve prosthesis. The endoprosthesis includes a first collapsed mode during the process of introducing it into the patient's body and a second expanded mode when it is implanted.
摘要翻译：用于治疗心脏瓣膜不全的医疗装置，其具有可被引入患者体内并扩张以将患者主动脉中的心脏瓣膜假体固定的内假体。在一个实施例中，内假体具有多个定位弓，其构造成相对于患者主动脉定位并且具有多个保持弓以支撑心脏瓣膜假体。内置假体包括在将其插入患者体内的过程中的第一折叠模式，以及植入时的第二扩张模式。

8. 发明授权

US07896915B2 Medical device for treating a heart valve insufficiency 有权
标题翻译：用于治疗心脏瓣膜不全的医疗装置
公开(公告)号：US07896915B2
公开(公告)日：2011-03-01
申请号：US11785072
申请日：2007-04-13
申请人： Volker Guyenot , Thomas Peschel , Christoph Damm , Hans-Reiner Figulla , Markus Ferrari , Johannes Jung
发明人： Volker Guyenot , Thomas Peschel , Christoph Damm , Hans-Reiner Figulla , Markus Ferrari , Johannes Jung
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/2442 , A61F2210/0014 , A61F2220/0008 , A61F2220/0016 , A61F2220/0075 , A61F2230/0013 , A61F2230/0054 , Y10T29/5116
摘要： A medical device for treating a heart valve insufficiency, with an endoprosthesis which can be introduced into a patient's body and expanded to secure a heart valve prosthesis in the patient's aorta. In an embodiment, the endoprosthesis has at plurality of positioning arches configured to be positioned with respect to a patient's aorta and a plurality of retaining arches to support a heart valve prosthesis. The endoprosthesis includes a first collapsed mode during the process of introducing it into the patient's body and a second expanded mode when it is implanted.
摘要翻译：用于治疗心脏瓣膜不全的医疗装置，其具有可被引入患者体内并扩张以将患者主动脉中的心脏瓣膜假体固定的内假体。在一个实施例中，内假体具有多个定位弓，其构造成相对于患者主动脉定位并且具有多个保持弓以支撑心脏瓣膜假体。内置假体包括在将其插入患者体内的过程中的第一折叠模式，以及植入时的第二扩张模式。

9. 发明授权

US07198646B2 Device for fastening and anchoring cardiac valve prostheses 有权
标题翻译：用于紧固和固定心脏瓣膜假体的装置
公开(公告)号：US07198646B2
公开(公告)日：2007-04-03
申请号：US10204990
申请日：2001-02-28
申请人： Hans-Reiner Figulla , Markus Ferrari , Carsten Weber , Thomas Peschel , Christoph Damm
发明人： Hans-Reiner Figulla , Markus Ferrari , Carsten Weber , Thomas Peschel , Christoph Damm
IPC分类号： A61F2/06 , A61F2/24
CPC分类号： A61F2/2418 , A61F2230/0054 , Y10S623/90
摘要： This invention relates to a device for fastening and anchoring heart valve prostheses which is essentially formed of wire-shaped interconnected elements. The aim of the invention is to be able to be implant, in a minimally invasive manner, a device of this type via the aorta by compressing the device to make it smaller, and by extending the same at the site of implantation, whereby ensuring a secure retention and a secure sealing with regard to the aorta wall. To this end, the invention provides that for fastening and supporting a cardiac valve prosthesis, three identical pairs of arched elements are interconnected, with a configuration that is offset by 120°, by means of solid body articulations. These solid body articulations carry out the function of pivot bearings.
摘要翻译：本发明涉及一种用于紧固和锚定心脏瓣膜假体的装置，其基本上由线状互连元件形成。本发明的目的是能够以微创的方式通过压缩该装置以使其更小并通过在植入部位延伸而将该装置以微创方式植入到主动脉中，从而确保保持固定和对主动脉壁的安全密封。为此，本发明提供了用于紧固和支撑心脏瓣膜假体的三个相同的拱形元件对，通过固体关节连接，其构造被偏移120°。这些实心铰接件具有枢轴轴承的功能。

10. 发明申请

US20110238159A1 MEDICAL DEVICE FOR TREATING A HEART VALVE INSUFFICIENCY 有权
标题翻译：用于治疗心脏瓣膜不适的医疗装置
公开(公告)号：US20110238159A1
公开(公告)日：2011-09-29
申请号：US13030708
申请日：2011-02-18
申请人： VOLKER GUYENOT , Thomas Peschel , Christoph Damm , Hans-Reiner Figulla , Markus Ferrari , Johannes Jung
发明人： VOLKER GUYENOT , Thomas Peschel , Christoph Damm , Hans-Reiner Figulla , Markus Ferrari , Johannes Jung
IPC分类号： A61F2/82
CPC分类号： A61F2/2418 , A61F2/2442 , A61F2210/0014 , A61F2220/0008 , A61F2220/0016 , A61F2220/0075 , A61F2230/0013 , A61F2230/0054 , Y10T29/5116
摘要： A medical device for treating a heart valve insufficiency, with an endoprosthesis which can be introduced into a patient's body and expanded to secure a heart valve prosthesis in the patient's aorta. In an embodiment, the endoprosthesis has at plurality of positioning arches configured to be positioned with respect to a patient's aorta and a plurality of retaining arches to support a heart valve prosthesis. The endoprosthesis includes a first collapsed mode during the process of introducing it into the patient's body and a second expanded mode when it is implanted.
摘要翻译：用于治疗心脏瓣膜不全的医疗装置，其具有可被引入患者体内并扩张以将患者主动脉中的心脏瓣膜假体固定的内假体。在一个实施例中，内假体具有多个定位弓，其构造成相对于患者主动脉定位并且具有多个保持弓以支撑心脏瓣膜假体。内置假体包括在将其插入患者体内的过程中的第一折叠模式，以及植入时的第二扩张模式。

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