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    • 7. 发明授权
    • Analysis system for determining an analyte in a body fluid and disposable integrated sample acquisition and analysis element
    • 用于确定体液中的分析物和一次性综合样品采集和分析元件的分析系统
    • US08114028B2
    • 2012-02-14
    • US12548479
    • 2009-08-27
    • Hans ListVolker ZimmerMichael Keil
    • Hans ListVolker ZimmerMichael Keil
    • A61B5/00
    • A61B5/157A61B5/150022A61B5/150175A61B5/150358A61B5/150435A61B5/150511A61B5/150572A61B5/15186A61B2562/0295
    • An analyte determination analysis system with a disposable integrated sample acquisition and analysis element is disclosed. A piercing element has a tip for generating a bodily puncture wound and a test strip having a body fluid sample receiving zone to perform an analysis on a body fluid sample. A reusable analysis instrument comprises a coupling unit that couples the integrated sample acquisition and analysis element to a drive that drives a piercing element in a piercing movement comprising two phases: a propulsion phase wherein the piercing element moves on a puncture path in a puncture direction and a retraction phase wherein the piercing element moves opposite to the puncture direction after reaching a reversal point. A measuring and analysis unit measures a variable characteristic for the determination of the analyte and determines a desired analysis result on the basis of the measurement. The sample receiving zone of the test strip forms a sample contact. The piercing element, located parallel to the test strip, moves on a movement path relative to the test strip a puncture path. The piercing element, located adjacent to the sample contact, has a capillary channel with a sample inlet for body fluid entry after the piercing and a sample outlet for body fluid exit. The piercing element movement has a sample transfer position wherein the sample outlet is adjacent to the sample receiving zone such that the body fluid may be transferred from the capillary channel through the sample outlet to the sample receiving zone.
    • 公开了一种具有一次性集成样品采集和分析元件的分析物测定分析系统。 穿刺元件具有用于产生身体穿刺伤口的尖端和具有体液样品接收区以对体液样品进行分析的测试条。 一种可重复使用的分析仪器包括耦合单元,该耦合单元将集成采样和分析元件耦合到驱动器,该驱动器以穿刺运动的方式驱动穿刺元件,所述穿孔运动包括两相:推进阶段,其中穿刺元件在穿刺方向上在穿刺路径上移动, 其中穿刺元件在达到反转点之后与穿刺方向相反移动。 测量和分析单元测量用于测定分析物的可变特性,并且基于测量确定期望的分析结果。 测试条的样品接收区形成样品接触。 刺穿元件平行于测试条移动,相对于测试条在穿刺路径上移动。 位于邻近样品接触处的刺穿元件具有毛细通道,其具有用于在穿刺之后进入体液的样品入口和用于体液排出的样品出口。 穿刺元件移动具有样品转移位置,其中样品出口与样品接收区相邻,使得体液可以从毛细通道通过样品出口转移到样品接收区。