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1. 发明授权

US4712555A Physiologically responsive pacemaker and method of adjusting the pacing interval thereof 失效
标题翻译：生理反应起搏器和调整其起搏间隔的方法
公开(公告)号：US4712555A
公开(公告)日：1987-12-15
申请号：US716831
申请日：1985-03-27
申请人： Hans T. Thornander , John W. Poore , Jason A. Sholder , James R. Thacker , David C. Amundson
发明人： Hans T. Thornander , John W. Poore , Jason A. Sholder , James R. Thacker , David C. Amundson
IPC分类号： A61N1/08 , A61N1/365 , A61N1/368 , A61N1/37 , A61N1/36
CPC分类号： A61N1/365 , A61N1/368 , A61N1/3712 , A61N1/3714 , A61N1/3716
摘要： A pacemaker and physiological sensor for use therewith that allows the rate at which the pacemaker delivers electrical stimulation pulses to the heart, or the escape interval during which a natural heart event must occur before an electrical stimulation pulse is delivered, to be adjusted as needed in order to satisfy the body's physiological needs. The sensor measures the depolarization time interval between an atrial stimulation pulse, A, and the responsive atrial or ventricle depolarization, P or R respectively, as an indication of the physiological demands placed on the heart. The time interval between a ventricular stimulation pulse, V, and the responsive ventricular depolarization, R, may also be measured and used as an indication of physiological need, and hence as an alternative criteria for rate control. Atrial depolarization is sensed by detecting a P-wave, and ventricular depolarization is preferably sensed by detecting an R-wave. A method of measuring A-P, A-R, or V-R intervals is used to ascertain if these intervals are increasing or decreasing. If, over several heart cycles or beats, an increase or decrease in these measurements is detected, the pacing interval set by the pacemaker is adjusted in an appropriate direction in order to adjust the heart stimulation rate accordingly.
摘要翻译：用于其的起搏器和生理传感器允许起搏器向心脏传递电刺激脉冲的速率，或者在传送电刺激脉冲之前必须发生自然心脏事件的逃逸间隔，以根据需要进行调整为了满足身体的生理需要。传感器测量心房刺激脉冲A与反应性心房或心室去极化P或R之间的去极化时间间隔，作为对心脏的生理需求的指示。也可以测量心室刺激脉冲V与响应性心室去极化R之间的时间间隔，并将其用作生理需要的指示，并因此用作速率控制的替代标准。通过检测P波来感测心房去极化，并且优选通过检测R波来感测心室去极化。使用测量A-P，A-R或V-R间隔的方法来确定这些间隔是否增加或减少。如果在几个心脏周期或节拍中检测到这些测量值的增加或减少，起搏器设定的起搏间隔将在适当的方向进行调节，以便相应地调整心脏刺激速率。

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