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1. 发明授权

US4807632A Measuring instrument for intracardial acquisition of the blood oxygen saturation of a patient for controlling the pacing rate of a heart pacemaker 失效
标题翻译：用于心脏内采集患者血氧饱和度的测量仪器，用于控制心脏起搏器的起搏速率
公开(公告)号：US4807632A
公开(公告)日：1989-02-28
申请号：US52032
申请日：1987-05-19
申请人： Hans D. Liess , Roland Heinze
发明人： Hans D. Liess , Roland Heinze
IPC分类号： G01N33/49 , A61B5/00 , A61B5/145 , A61B5/1459 , A61B5/1473 , A61N1/365 , G01D18/00
CPC分类号： A61B5/1459 , A61N1/36557
摘要： A measuring instrument for the intracardial acquistion of the blood oxygen saturation of a patient for use in controlling a heart pacemaker implanted in the patient has a measuring probe with a measuring current path which includes a light transmitter and a light receiver which receives light emitted by the light transmitter and reflected by the blood. The measuring probe is connected to an evaluation circuit via two lines. A useful signal measurement and a reference measurement, independent of the blood reflection, are made and the blood oxygen saturation is identified by comparing the two signals. A separate evaluation of the useful signal measurement and the reference signal measurement is enabled by making the useful signal measurement chronologically offset with respect to the reference measurement in one embodiment, or by using the amplitude of the current from the light receiver to make one measurement, and using the voltage amplitude to make the other measurement in another embodiment.
摘要翻译：用于心脏采集患者的血氧饱和度用于控制植入患者的心脏起搏器的测量仪器具有测量电流路径的测量探头，该测量电流路径包括光发射器和接收由光发射器和血液反射。测量探头通过两条线连接到评估电路。进行独立于血液反射的有用的信号测量和参考测量，并通过比较两个信号来识别血氧饱和度。通过使有用信号测量在一个实施例中相对于参考测量按时间顺序偏移，或者通过使用来自光接收器的电流的振幅进行一次测量，可以对有用信号测量和参考信号测量进行单独的评估，并且在另一实施例中使用电压幅度进行另一测量。

2. 发明授权

US4399820A Process and device for regulating the stimulation frequency of heart pacemakers 失效
标题翻译：调节心脏起搏器刺激频率的过程和装置
公开(公告)号：US4399820A
公开(公告)日：1983-08-23
申请号：US346315
申请日：1982-02-05
申请人： Alexander Wirtzfeld , Roland Heinze , Thomas Bock , Hans D. Liess
发明人： Alexander Wirtzfeld , Roland Heinze , Thomas Bock , Hans D. Liess
IPC分类号： A61B5/00 , A61B5/145 , A61B5/1459 , A61N1/365 , A61N1/36
CPC分类号： A61N1/36557 , A61B5/1459
摘要： A process and a device for regulating the stimulation frequency of heart pacemakers are disclosed. The process comprises generating with the aid of light emitted by a light-emitting element, reflected by the blood of a patient, and received by a light-receiving element, a current flow which causes, in a measuring probe, an increasing of the current flow at a constant probe voltage or a damping of the probe voltage at constant current flow. Thereafter, one of the possible changing values is measured and the change, with time, is evaluated as a measured quantity proportional to the change, with time, of the blood oxygen saturation, and, as a function of the measured quantity, the stimulation frequency of the heart pacemaker is regulated in such a manner that the greatest possible blood oxygen saturation is always achieved with the lowest stimulation frequency. The device for practicing the invention comprises a measuring probe containing at least one combination of only two active optoelectronic elements, one light-emitting element and one light-receiving element; a control circuit electrically connected to the measuring probe; a stimulation catheter in which the measuring probe is incorporated, and at least two electric lines leading through the stimulation catheter and electrically connecting the measuring probe to the control circuit of the measuring probe.
摘要翻译：公开了一种用于调节心脏起搏器刺激频率的过程和装置。该过程包括借助由发光元件发射的光产生，由患者的血液反射并由光接收元件接收的电流，其在测量探针中引起电流的增加在恒定电流下以恒定的探针电压或探针电压的阻尼流动。此后，测量可能的变化值之一，随时间的变化被评估为与血氧饱和度随时间的变化成比例的测量量，并且作为测量量的函数，刺激频率心脏起搏器的调节方式是以最低的刺激频率始终实现最大可能的血氧饱和度。用于实施本发明的装置包括测量探头，其包含仅两个有源光电元件，一个发光元件和一个光接收元件的至少一个组合; 电连接到所述测量探针的控制电路; 其中结合有测量探针的刺激导管和通过刺激导管的至少两条电线，并将测量探针电连接到测量探针的控制电路。

3. 发明授权

US4870967A Measuring arrangement for controlling an implantable body-assist device 失效
标题翻译：用于控制可植入身体辅助装置的测量装置
公开(公告)号：US4870967A
公开(公告)日：1989-10-03
申请号：US84204
申请日：1987-08-12
申请人： Roland Heinze , Hans D. Liess
发明人： Roland Heinze , Hans D. Liess
IPC分类号： A61F2/48 , A61B5/0402 , A61B5/0408 , A61B5/0478 , A61B5/0492 , A61B5/05 , A61B5/145 , A61N1/05 , A61N1/365 , G01N27/416
CPC分类号： A61N1/3655
摘要： An implantable arrangement for operating a body-assist device, the body-assist device including circuitry for generating electrical signals and also being implanted in a patient, includes circuitry for controlling the generation of the electric signals, a measuring probe in the patient for obtaining signals to be used by the control circuitry, a single current conductor electrically connecting the control circuitry and the measuring probe and forming a first current path therebetween, and spaced electrodes connected to the measuring probe and the control circuitry disposed in the patient with body tissue therebetween such that a second current path is formed in the body tissue.
摘要翻译：一种用于操作身体辅助装置的可植入装置，所述身体辅助装置包括用于产生电信号并且还植入患者体内的电路，包括用于控制电信号的产生的电路，用于获得信号的患者中的测量探针由控制电路使用的单电流导体，电连接控制电路和测量探针并在它们之间形成第一电流路径，以及间隔开的电极，其连接到测量探针和设置在患者体内的身体组织的控制电路之间，在身体组织中形成第二电流路径。

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