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1. 发明申请

US20130267954A1 ANTI-INFECTIVE SPACER FOR OSTEOSYNTHESIS PLATES 有权
标题翻译：用于骨质疏松板的抗感染间隔物
公开(公告)号：US20130267954A1
公开(公告)日：2013-10-10
申请号：US13799870
申请日：2013-03-13
申请人： Heraeus Medical GmbH
发明人： Sebastian Vogt , Klaus-Dieter Kühn
IPC分类号： A61B17/80
CPC分类号： A61B17/8028 , A61B2017/00889 , A61B2017/00893 , A61F2250/0067
摘要： The invention relates to an anti-infective spacer for osteosynthesis plates comprising a plate having at least one opening for accommodating a screw, whereby the plate is made up of at least one biocompatible material, in which at least one antimicrobial substance is distributed, dispersed or dissolved. The invention also relates to a set comprising at least one osteosynthesis plate and at least one said spacer, preferably comprising at least one screw for each recess of each spacer.
摘要翻译：本发明涉及一种用于骨接合术板的抗感染性间隔物，其包括具有用于容纳螺钉的至少一个开口的板，由此该板由至少一种生物相容性材料制成，其中至少一种抗微生物物质被分散或分散，溶解。本发明还涉及包含至少一个骨接合板和至少一个所述间隔物的组，其优选地包括用于每个间隔物的每个凹部的至少一个螺钉。

2. 发明授权

US09833472B2 Antiseptic polymethylmethacrylate bone cement 有权
公开(公告)号：US09833472B2
公开(公告)日：2017-12-05
申请号：US14081180
申请日：2013-11-15
申请人： HERAEUS MEDICAL GMBH
发明人： Sebastian Vogt , Klaus-Dieter Kühn
IPC分类号： C08L33/12 , A61K33/40 , A61L24/00
CPC分类号： A61K33/40 , A61L24/0015 , A61L2300/11 , A61L2430/02 , C08L33/12 , C08L2312/00
摘要： The invention proposes an antiseptic composition for use as bone cement, in particular an antiseptic polymethylmethacrylate bone cement, that can be cured and comprises a content of at least one component that is a compound with an oxidizing effect or from which a compound with an oxidizing effect can be released. Preferably, hydrogen peroxide is or can be released. In this context, it is particularly preferred to use an adduct or a salt of hydrogen peroxide that releases hydrogen peroxide in the presence of water or aqueous conditions. The antiseptic polymethylmethacrylate bone cement can be used for mechanical fixation of primary total articular endoprostheses, for mechanical fixation of revision total articular endoprostheses, and for producing spacers.

3. 发明授权

US09241746B2 Anti-infective spacer for osteosynthesis plates 有权
标题翻译：用于骨接合板的抗感染间隔物
公开(公告)号：US09241746B2
公开(公告)日：2016-01-26
申请号：US13799870
申请日：2013-03-13
申请人： Heraeus Medical GmbH
发明人： Sebastian Vogt , Klaus-Dieter Kühn
IPC分类号： A61B17/80 , A61B17/00
CPC分类号： A61B17/8028 , A61B2017/00889 , A61B2017/00893 , A61F2250/0067
摘要： The invention relates to an anti-infective spacer for osteosynthesis plates comprising a plate having at least one opening for accommodating a screw, whereby the plate is made up of at least one biocompatible material, in which at least one antimicrobial substance is distributed, dispersed or dissolved. The invention also relates to a set comprising at least one osteosynthesis plate and at least one said spacer, preferably comprising at least one screw for each recess of each spacer.
摘要翻译：本发明涉及一种用于骨接合术板的抗感染性间隔物，其包括具有用于容纳螺钉的至少一个开口的板，由此该板由至少一种生物相容性材料制成，其中至少一种抗微生物物质被分散或分散，溶解。本发明还涉及包含至少一个骨接合板和至少一个所述间隔物的组，其优选地包括用于每个间隔物的每个凹部的至少一个螺钉。

4. 发明授权

US09700657B2 Bio-absorbable composite materials containing magnesium and magnesium alloys as well as implants made of said composites 有权
公开(公告)号：US09700657B2
公开(公告)日：2017-07-11
申请号：US14337492
申请日：2014-07-22
申请人： HERAEUS MEDICAL GMBH , MEDIZINISCHE UNIVERSITÄT GRAZ
发明人： Klaus-Dieter Kühn , Annelie Weinberg , Peter Uggowitzer , Sebastian Vogt , Jörg Löffler
IPC分类号： A61L31/12 , A61F2/88 , A61L27/04 , A61L27/54 , A61L27/58 , A61L31/02 , A61L31/14 , A61L31/16 , C22C21/06
CPC分类号： A61L31/124 , A61F2/885 , A61F2220/005 , A61L27/047 , A61L27/54 , A61L27/58 , A61L31/028 , A61L31/148 , A61L31/16 , A61L2300/206 , A61L2300/23 , A61L2300/406 , A61L2300/414 , C22C21/06
摘要： The invention relates to a composite material that comprises at least one magnesium component, whereby the magnesium component consists of pure magnesium or a magnesium-calcium alloy or a magnesium-calcium-X alloy, whereby X is another biodegradable element. The composite material also contains at least one organic anti-infective agent having a solubility in water at room temperature of less than 10 grams per liter.

5. 发明申请

US20140141097A1 ANTISEPTIC POLYMETHYLMETHACRYLATE BONE CEMENT 有权
标题翻译：抗粘蛋白聚甲基丙烯酸酯骨水泥
公开(公告)号：US20140141097A1
公开(公告)日：2014-05-22
申请号：US14081180
申请日：2013-11-15
申请人： HERAEUS MEDICAL GMBH
发明人： Sebastian VOGT , Klaus-Dieter Kühn
IPC分类号： A61K33/40
CPC分类号： A61K33/40 , A61L24/0015 , A61L2300/11 , A61L2430/02 , C08L33/12 , C08L2312/00
摘要： The invention proposes an antiseptic composition for use as bone cement, in particular an antiseptic polymethylmethacrylate bone cement, that can be cured and comprises a content of at least one component that is a compound with an oxidising effect or from which a compound with an oxidising effect can be released. Preferably, hydrogen peroxide is or can be released. In this context, it is particularly preferred to use an adduct or a salt of hydrogen peroxide that releases hydrogen peroxide in the presence of water or aqueous conditions. The antiseptic polymethylmethacrylate bone cement can be used for mechanical fixation of primary total articular endoprostheses, for mechanical fixation of revision total articular endoprostheses, and for producing spacers.
摘要翻译：本发明提出了一种用作骨水泥，特别是防腐聚甲基丙烯酸甲酯骨水泥的防腐组合物，其可以固化，并且包含至少一种作为具有氧化作用的化合物或具有氧化作用的化合物的组分的含量可以释放优选地，过氧化氢是或可以释放的。在本文中，特别优选使用在水或水溶液条件存在下释放过氧化氢的过氧化氢的加合物或盐。防腐聚甲基丙烯酸甲酯骨水泥可用于初级全关节内假体的机械固定，修复全关节内假体的机械固定，以及用于制备间隔物。

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