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1. 发明授权

US09428711B2 Chromatographic process for the production of highly purified polyunsaturated fatty acids 有权
标题翻译：用于生产高纯度多不饱和脂肪酸的色谱法
公开(公告)号：US09428711B2
公开(公告)日：2016-08-30
申请号：US14149420
申请日：2014-01-07
申请人： Groupe Novasep SAS
发明人： Philippe Adam , Eric Valéry , Jean Bléhaut
IPC分类号： C11B7/00 , C11C1/00
CPC分类号： C11B7/0025 , C11B7/0008 , C11C1/005 , C11C1/007
摘要： A process is provided for recovering a first polyunsaturated fatty acid (PUFA) from a feed mixture including at least one additional fatty acid (e.g., a second fatty acid (FA)). The process optionally comprises: performing a main step of chromatographic separation using an aqueous organic eluent and collecting a first stream of eluent enriched in the first PUFA and a second stream of eluent enriched in the second FA; subjecting the second stream of eluent to a partial concentration step to obtain a concentrated portion including the second FA, and a depleted portion comprising eluent, but depleted of the second FA. The process also includes: at least partially recycling the depleted portion for use in the main step of chromatographic separation.
摘要翻译：提供了一种从包含至少一种另外的脂肪酸（例如第二脂肪酸（FA））的进料混合物中回收第一多不饱和脂肪酸（PUFA）的方法。所述方法任选地包括：使用含水有机洗脱液进行色谱分离的主要步骤，并收集富含第一PUFA的第一洗脱液流和富含第二FA的第二洗脱液流; 使第二流的洗脱液进行部分浓缩步骤以获得包括第二FA的浓缩部分和包含洗脱液但是耗尽第二FA的贫化部分。该方法还包括：至少部分地循环耗尽部分以用于色谱分离的主要步骤。

2. 发明授权

US08802880B1 Chromatographic process for the production of highly purified polyunsaturated fatty acids 有权
标题翻译：用于生产高纯度多不饱和脂肪酸的色谱法
公开(公告)号：US08802880B1
公开(公告)日：2014-08-12
申请号：US13897056
申请日：2013-05-17
申请人： Groupe Novasep SAS
发明人： Philippe Adam , Eric Valéry , Jean Bléhaut
IPC分类号： C11B3/00
CPC分类号： C11C1/007 , C11B7/0008 , C11B7/0025 , C11C1/005
摘要： A process is provided for recovering a first polyunsaturated fatty acid (PUFA) from a feed mixture including at least one additional fatty acid (e.g., a second fatty acid (FA)). The process optionally comprises: performing a main step of chromatographic separation using an aqueous organic eluent and collecting a first stream of eluent enriched in the first PUFA and a second stream of eluent enriched in the second FA; subjecting the second stream of eluent to a concentration step to obtain a concentrated portion including the second FA, and a depleted portion comprising eluent, but depleted of the second FA. The water-to-organic ratio of the depleted portion is lower than the water-to-organic ratio of the second stream of eluent. The process also includes: at least partially recycling the depleted portion for use in the main step of chromatographic separation.
摘要翻译：提供了一种从包含至少一种另外的脂肪酸（例如第二脂肪酸（FA））的进料混合物中回收第一多不饱和脂肪酸（PUFA）的方法。所述方法任选地包括：使用含水有机洗脱液进行色谱分离的主要步骤，并收集富含第一PUFA的第一洗脱液流和富含第二FA的第二洗脱液流; 将第二流洗脱液经受浓缩步骤以获得包括第二FA的浓缩部分，以及包含洗脱液但耗尽第二FA的贫化部分。耗尽部分的水与有机比率低于第二流洗脱液的水与有机比。该方法还包括：至少部分地循环耗尽部分以用于色谱分离的主要步骤。

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