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1. 发明授权

US06667923B1 RAM data array configured to provide data-independent, write cycle coherent current drain 有权
标题翻译： RAM数据阵列配置为提供数据无关，写周期相干电流消耗
公开(公告)号：US06667923B1
公开(公告)日：2003-12-23
申请号：US10205862
申请日：2002-07-26
申请人： Gregory Jay DelMain , John Gord , Lawrence J. Karr , Paul De Rocco , Glenn A. DeMichele , Douglas Kerns , Andrew Barber
发明人： Gregory Jay DelMain , John Gord , Lawrence J. Karr , Paul De Rocco , Glenn A. DeMichele , Douglas Kerns , Andrew Barber
IPC分类号： G11C702
CPC分类号： G11C7/1036
摘要： An apparatus and method for forming a RAM data memory that generates predictable noise/interference components that are coherent with each write cycle and essentially independent of the data content of the RAM data memory. The RAM data memory is comprised of a plurality of cells, each representing a data bit, which are selectively addressable as memory bytes formed of multiple bits. Each cell is formed of two sets of cross-coupled transistors. By causing each set of cross-coupled transistors to be set to a common voltage level at the beginning of a write cycle before setting one set of transistors to a low level and the one set of transistors to be set to a high level (thus representing a desired data bit value), the associated noise/interference components of the power drain are data independent. Furthermore, the data-independent noise occurs at frequencies at or above the write cycle rate.
摘要翻译：一种用于形成RAM数据存储器的装置和方法，所述RAM数据存储器产生与每个写周期相干并且基本上独立于RAM数据存储器的数据内容的可预测的噪声/干扰分量。 RAM数据存储器由多个单元组成，每个单元表示数据位，其可选择地可寻址为由多位形成的存储器字节。每个单元由两组交叉耦合晶体管组成。通过在将一组晶体管设置为低电平并且将一组晶体管设置为高电平（从而代表一个晶体管的一组）之前，将每组交叉耦合晶体管设置为写周期开始时的公共电压电平期望的数据位值），功率相关的噪声/干扰分量是数据无关的。而且，数据无关的噪声出现在等于或高于写周期速率的频率。

2. 发明授权

US06774157B2 Biocompatible medical devices with polyurethane surface 有权
标题翻译：具有聚氨酯表面的生物相容性医疗器械
公开(公告)号：US06774157B2
公开(公告)日：2004-08-10
申请号：US09962727
申请日：2001-09-25
申请人： Gregory Jay DelMain
发明人： Gregory Jay DelMain
IPC分类号： B05D304
CPC分类号： C08J7/02 , A61L29/06 , A61L33/068 , C08J2375/04 , C08L75/04
摘要： A system for improving the biocompatibility of medical devices present within a patient's body. In one embodiment, the present subject matter reduces the thrombogenicity of polyurethane materials in contact with the blood of a patient. In one embodiment, the medical device has a polymeric wall and a coating of polyurethane, said coating of polyurethane having the same chemical composition throughout the thickness and displaying an antithrombogenic effect when inserted into a patient's body in contact with blood for a period of at least twenty-four hours. The present subject matter relates to the manufacture and treatment of polymeric materials that may be inserted as medical devices, accessories, implants or replacements into animal bodies, such as the human body.
摘要翻译：用于改善存在于患者体内的医疗装置的生物相容性的系统。在一个实施方案中，本主题降低与患者的血液接触的聚氨酯材料的血栓形成性。在一个实施方案中，医疗装置具有聚合物壁和聚氨酯涂层，所述聚氨酯涂层在整个厚度上具有相同的化学组成，并且当插入患者体内与血液接触至少一段时间时，具有抗血栓形成作用二十四小时。本主题涉及可以作为医疗装置，附件，植入物或替代物插入动物体例如人体的聚合物材料的制造和处理。

3. 发明授权

US06959217B2 Multi-mode crystal oscillator system selectively configurable to minimize power consumption or noise generation 有权
标题翻译：多模式晶体振荡器系统可选择配置以最小化功耗或产生噪声
公开(公告)号：US06959217B2
公开(公告)日：2005-10-25
申请号：US10280841
申请日：2002-10-24
申请人： Gregory Jay DelMain , John C. Gord , Paul DeRocco
发明人： Gregory Jay DelMain , John C. Gord , Paul DeRocco
IPC分类号： A61N1/08 , H03K3/012 , H03K3/013 , H03K3/03 , H03K3/354 , A61N1/00
CPC分类号： A61N1/08 , H03L7/00 , Y10S323/911
摘要： The present invention is directed to a multi-mode crystal oscillator system selectively configurable to minimize power consumption or noise generation. Such a system is particularly applicable to the communication system of an implantable device, e.g., the microstimulator/sensor device described in U.S. Pat. Nos. 6,164,284 and 6,185,452. In such devices, their small size limits the size of the battery contained within and thus makes it essential to minimize power consumption. Additionally, the small size and battery capacity result in a limited transmission power. Furthermore, the small size limits the antenna efficiency which makes it desirable to limit any noise generation to maximize the signal-to-noise level of the resulting receive signal. Accordingly, embodiments of the present invention alternatively supply power to the oscillator in either a first mode that minimizes power consumption or a second mode that minimizes noise generation.
摘要翻译：本发明涉及一种多模式晶体振荡器系统，其选择性地可配置以最小化功率消耗或产生噪声。这样的系统特别适用于可植入装置的通信系统，例如美国专利No. 6,164,284和6,185,452号。在这样的设备中，它们的小尺寸限制了包含在其中的电池的尺寸，并且因此使得最小化功率消耗成为必要。此外，小尺寸和电池容量导致有限的发射功率。此外，小尺寸限制了天线效率，这使得期望限制任何噪声产生以使得到的接收信号的信噪比水平最大化。因此，本发明的实施例可以以最小化功耗的第一模式或使噪声产生最小化的第二模式向振荡器供电。

4. 发明授权

US06323256B1 Biocompatible medical devices with polyurethane surface 有权
标题翻译：具有聚氨酯表面的生物相容性医疗器械
公开(公告)号：US06323256B1
公开(公告)日：2001-11-27
申请号：US09329869
申请日：1999-06-11
申请人： Gregory Jay DelMain
发明人： Gregory Jay DelMain
IPC分类号： B05D304
CPC分类号： C08J7/02 , A61L29/06 , A61L33/068 , C08J2375/04 , C08L75/04
摘要： The present invention provides a method for improving the biocompatibility of devices, especially medical devices which are invasively present within a patient's body and the improved medical device. The present invention particularly reduces the thrombogenicity of polyurethane materials in contact with the blood of a living patient. The method comprises providing a biocompatible medical device having polymeric polyurethane components thereon, exposing the polyurethane components of the medical device to polar solvents for said polymeric components while the polar solvents are in the vapor phase, and allowing said vapor phase exposure to continue for a sufficient amount of time as to reduce at least some irregular or sharp features on the surface of the polymeric component. The invention describes a method of improving a medical device having at least one polymeric component, the process comprising the steps of providing a vapor phase comprising a solvent for said polymer component, and exposing said polymeric component to said vapor phase. The process comprises taking a polyurethane component having a surface with a topography (e.g., roughness, grooves, wave patterns, sharp edge features, deviations from planarity and the like), and exposing the polyurethane component to said vapor phase to increase planarity in said topography. This is done without chemical reaction with the polymer component, and because of the control of the amount of solvent which can contact the polymer, the potential for damage to the polymeric component is reduced. In particular, the vapor phase treatment will reduce the dimensions of extrusion markings on the exterior surface of the polyurethane with minimum potential for damage to the structure of the polyurethane, even where the polyurethane is present as thin walls (e.g., less than 0.0762 mm).
摘要翻译：本发明提供一种用于改善设备，特别是侵入地存在于患者体内的医疗设备和改进的医疗设备的生物相容性的方法。本发明特别降低与活体患者的血液接触的聚氨酯材料的血栓形成。该方法包括在其上提供具有聚合物聚氨酯组分的生物相容性医疗装置，将所述医疗装置的聚氨酯组分暴露于所述聚合物组分的极性溶剂，同时极性溶剂处于气相，并允许所述气相暴露持续足够的用于减少聚合物组分表面上至少一些不规则或尖锐特征的时间量。本发明描述了改进具有至少一种聚合物组分的医疗装置的方法，该方法包括以下步骤：提供包含所述聚合物组分的溶剂的气相，并将所述聚合物组分暴露于所述气相。该方法包括使具有表面的聚氨酯组分具有形貌（例如，粗糙度，凹槽，波形图案，尖锐边缘特征，与平面度偏差等），并将聚氨酯组分暴露于所述气相以增加所述形貌中的平面度。这完成了与聚合物组分的化学反应，并且由于可以控制可以与聚合物接触的溶剂的量，所以降低了对聚合物组分的损害的可能性。特别地，气相处理将减小聚氨酯外表面上挤出标记的尺寸，即使在聚氨酯以薄壁（例如，小于0.0762mm）存在聚氨酯的结构的情况下，也可能损坏聚氨酯的结构，。

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