专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20070032642A1 Novel genes and their use in the modulation of obesity, diabetes and energy imbalance 审中-公开
标题翻译：新型基因及其在调节肥胖，糖尿病和能量失衡中的应用
公开(公告)号：US20070032642A1
公开(公告)日：2007-02-08
申请号：US11544140
申请日：2006-10-06
申请人： Gregory Collier , Paul Zimmet , Kenneth Walder , Kelly Windmill , Janine McMillan
发明人： Gregory Collier , Paul Zimmet , Kenneth Walder , Kelly Windmill , Janine McMillan
IPC分类号： C07H21/04
CPC分类号： C07K14/47 , A61K38/00
摘要： The present invention relates generally to nucleic acid molecules encoding proteins associated with the modulation of obesity, diabetes and/or metabolic energy levels. More particularly, the present invention is directed to nucleic acid molecules and the recombinant and purified proteins encoded thereby and their use in therapeutic and diagnostic protocols for conditions such as obesity, diabetes and energy imbalance. The subject nucleic acid molecules and proteins and their derivatives, homologs, analogs, chemical equivalents and mimetics are proposed as therapeutic and diagnostic agents for obesity, diabetes and energy imbalance.
摘要翻译：本发明一般涉及编码与肥胖，糖尿病和/或代谢能量水平的调节相关的蛋白质的核酸分子。更具体地，本发明涉及由此编码的核酸分子和重组和纯化的蛋白质，以及它们在治疗和诊断方案中用于诸如肥胖症，糖尿病和能量失衡的病症的用途。提出了本研究的核酸分子和蛋白质及其衍生物，同系物，类似物，化学当量和模拟物，作为肥胖，糖尿病和能量失衡的治疗和诊断剂。

2. 发明申请

US20070281986A1 Methods and Compositions for Modulating Satiety 审中-公开
标题翻译：调节饱腹感的方法和组合
公开(公告)号：US20070281986A1
公开(公告)日：2007-12-06
申请号：US10588576
申请日：2005-02-01
申请人： Gregory Collier , Kenneth Walder
发明人： Gregory Collier , Kenneth Walder
IPC分类号： A61K31/4178
CPC分类号： G01N33/6872 , A61K31/4178 , A61K33/24 , A61K45/06 , G01N2500/02 , G01N2800/044
摘要： The present invention relates generally to a method for modulating the sensation of satiety perception and to agents useful for same. More particularly, the present invention identifies molecules which interact with ion channels thereby modulating the perception of satiety. The present invention contemplates, therefore, a method for modulating gastric distension by the administration of agents which control the activation or inhibition of mechanoreceptors. The present invention further provides compositions comprising these agents and methods of treatment using same. In a particular embodiment, the present invention permits modulation of the sensation of gastric distension by the administration of agents which control the activation of mechanoreceptors associated with mechanical stretch.
摘要翻译：本发明一般涉及一种调节饱腹感觉感觉的方法以及对其有用的药剂。更具体地，本发明鉴定与离子通道相互作用的分子，从而调节饱腹感。因此，本发明考虑了通过施用控制机械感受器的活化或抑制的试剂调节胃膨胀的方法。本发明还提供了包含这些试剂的组合物和使用它们的治疗方法。在一个具体实施方案中，本发明允许通过施用控制与机械拉伸相关的机械感受器的活化的试剂调节胃胀气的感觉。

3. 发明申请

US20060155111A9 Novel genes and their use in the modulation of obesity, diabetes and energy imbalance 审中-公开
公开(公告)号：US20060155111A9
公开(公告)日：2006-07-13
申请号：US10039050
申请日：2001-12-31
申请人： Gregory Collier , Paul Zimmet , Kenneth Walder , Kelly Windmill , Janine McMillan
发明人： Gregory Collier , Paul Zimmet , Kenneth Walder , Kelly Windmill , Janine McMillan
IPC分类号： C07K14/435 , C07H21/04 , C12P21/02 , C12N5/06
CPC分类号： C07K14/47 , A61K38/00
摘要： The present invention relates generally to nucleic acid molecules encoding proteins associated with the modulation of obesity, diabetes and/or metabolic energy levels. More particularly, the present invention is directed to nucleic acid molecules and the recombinant and purified proteins encoded thereby and their use in therapeutic and diagnostic protocols for conditions such as obesity, diabetes and energy imbalance. The subject nucleic acid molecules and proteins and their derivatives, homologs, analogs, chemical equivalents and mimetics are proposed as therapeutic and diagnostic agents for obesity, diabetes and energy imbalance.

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式