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1. 发明授权

US09102125B2 Printed flexible film for food packaging 有权
标题翻译：用于食品包装的打印柔性薄膜
公开(公告)号：US09102125B2
公开(公告)日：2015-08-11
申请号：US13390956
申请日：2010-08-26
申请人： Graham C. Battersby , Stephen A. Santos , Bin Zhong , Xiangdong Gan
发明人： Graham C. Battersby , Stephen A. Santos , Bin Zhong , Xiangdong Gan
IPC分类号： B29D22/00 , B32B27/08 , B65D65/40 , B41M7/02 , B32B27/36 , B41M7/00 , B32B27/32 , C09D193/02
CPC分类号： B32B27/08 , B32B9/02 , B32B9/04 , B32B15/04 , B32B15/20 , B32B27/06 , B32B27/304 , B32B27/306 , B32B27/32 , B32B27/34 , B32B27/36 , B32B2255/00 , B32B2255/06 , B32B2255/10 , B32B2255/26 , B32B2270/00 , B32B2307/412 , B32B2307/546 , B32B2307/7163 , B32B2307/7244 , B32B2307/7246 , B32B2307/75 , B32B2439/70 , B32B2439/80 , B41M7/0036 , B41M7/0045 , B41M7/02 , B65D65/40 , C09D193/02 , Y10T428/1334 , Y10T428/1379 , Y10T428/24851 , C08L71/02 , C08L89/00 , C08L1/28
摘要： The printed image on a major face of a flexible food packaging film is covered by a shellac barrier coating.
摘要翻译：柔性食品包装膜的主面上的印刷图像被虫胶屏障涂层覆盖。

2. 发明申请

US20120207887A1 PRINTED FLEXIBLE FILM FOR FOOD PACKAGING 有权
标题翻译：用于食品包装的打印柔性膜
公开(公告)号：US20120207887A1
公开(公告)日：2012-08-16
申请号：US13390956
申请日：2010-08-26
申请人： Graham C. Battersby , Stephen A. Santos , Bin Zhong , Xiangdong Gan
发明人： Graham C. Battersby , Stephen A. Santos , Bin Zhong , Xiangdong Gan
IPC分类号： B32B9/00 , B32B3/00
CPC分类号： B32B27/08 , B32B9/02 , B32B9/04 , B32B15/04 , B32B15/20 , B32B27/06 , B32B27/304 , B32B27/306 , B32B27/32 , B32B27/34 , B32B27/36 , B32B2255/00 , B32B2255/06 , B32B2255/10 , B32B2255/26 , B32B2270/00 , B32B2307/412 , B32B2307/546 , B32B2307/7163 , B32B2307/7244 , B32B2307/7246 , B32B2307/75 , B32B2439/70 , B32B2439/80 , B41M7/0036 , B41M7/0045 , B41M7/02 , B65D65/40 , C09D193/02 , Y10T428/1334 , Y10T428/1379 , Y10T428/24851 , C08L71/02 , C08L89/00 , C08L1/28
摘要： The printed image on a major face of a flexible food packaging film is covered by a shellac barrier coating.
摘要翻译：柔性食品包装膜的主面上的印刷图像被虫胶屏障涂层覆盖。

3. 发明授权

US08765239B2 Printed flexible film for food packaging 有权
公开(公告)号：US08765239B2
公开(公告)日：2014-07-01
申请号：US13390956
申请日：2010-08-26
申请人： Graham C. Battersby , Stephen A. Santos , Bin Zhong , Xiangdong Gan
发明人： Graham C. Battersby , Stephen A. Santos , Bin Zhong , Xiangdong Gan
IPC分类号： B29D22/00 , B32B27/08 , B65D65/40 , B41M7/02 , B41M7/00 , B32B27/32 , B32B27/36 , C09D193/02
摘要： The printed image on a major face of a flexible food packaging film is covered by a shellac barrier coating.

4. 发明申请

US20110236537A1 Coating for Iced or Glazed Frozen Food Products 有权
标题翻译：冰晶或釉面冷冻食品涂料
公开(公告)号：US20110236537A1
公开(公告)日：2011-09-29
申请号：US13133273
申请日：2009-12-07
申请人： Bin Zhong , Xiangdong Gan
发明人： Bin Zhong , Xiangdong Gan
IPC分类号： A23G3/54
CPC分类号： A21D15/02 , A21D13/24 , A21D13/28 , A21D13/60 , A23G3/343 , A23P20/10 , A23P20/105
摘要： The gloss of iced frozen baked goods once thawed, is enhanced by coating the baked goods with shellac prior to freezing.
摘要翻译：一旦解冻的冰冻冷冻烘焙食品的光泽度，在冻结之前用紫胶包衣烘焙食品可以增强。

5. 发明申请

US20080102497A1 ENZYMATIC HYDROLYSIS OF STARCH 审中-公开
标题翻译：淀粉酶水解
公开(公告)号：US20080102497A1
公开(公告)日：2008-05-01
申请号：US11619314
申请日：2007-01-03
申请人： Dominic Wong , Arun Kumar Uppalanchi , Xiangdong Gan , Bin Zhong
发明人： Dominic Wong , Arun Kumar Uppalanchi , Xiangdong Gan , Bin Zhong
IPC分类号： C12P19/04 , C12P19/02 , C12N9/32
CPC分类号： C12P19/14 , C12P19/20 , C12P19/22
摘要： Provided herein are methods of increasing the enzymatic rate of hydrolysis of starch substrates. In certain embodiments the method comprises contacting a starch substrate with one or more amylase family enzymes in the presence of greater than 0.001 mM manganese ions. In certain embodiments, the method comprises contacting a starch substrate with one or more glucoamylase and/or β-amylase enzymes in the presence of greater than 0.001 mM calcium ions (Ca++). In certain embodiments, the method comprises contacting the starch substrate with a β-amylase in the presence of greater than 0.001 mM manganese ion, calcium ion, magnesium ion (Mg++), strontium ion (Sr++), barium ion (Ba++) or any combination of said metal ions. In certain embodiments the method comprises contacting the starch substrate with a glucoamylase in the presence of greater than 0.001 mM manganese ion, calcium ion, lithium ion (Li+), potassium ion (K+), or any combination of said metal ions. Also provided herein are compositions and kits for hydrolyzing starch.
摘要翻译：本文提供了增加淀粉底物的酶水解速率的方法。在某些实施方案中，该方法包括在大于0.001mM锰离子的存在下使淀粉底物与一种或多种淀粉酶家族酶接触。在某些实施方案中，该方法包括在大于0.001mM钙离子（Ca ++）的存在下使淀粉底物与一种或多种葡糖淀粉酶和/或β-淀粉酶接触。在某些实施方案中，该方法包括在大于0.001mM的锰离子，钙离子，镁离子（Mg ++），锶离子（Sr < SUP + ++），钡离子（Ba ++）或所述金属离子的任何组合。在某些实施方案中，所述方法包括在大于0.001mM的锰离子，钙离子，锂离子（Li +）和/或离子（K +）的存在下使淀粉底物与葡糖淀粉酶接触， / SUP>）或所述金属离子的任何组合。本文还提供用于水解淀粉的组合物和试剂盒。

6. 发明授权

US09861107B2 Coating for iced or glazed frozen food products 有权
公开(公告)号：US09861107B2
公开(公告)日：2018-01-09
申请号：US13133273
申请日：2009-12-07
申请人： Bin Zhong , Xiangdong Gan
发明人： Bin Zhong , Xiangdong Gan
IPC分类号： A21D15/02 , A23G3/34 , A23P20/10 , A21D13/24 , A21D13/60 , A21D13/28
CPC分类号： A21D15/02 , A21D13/24 , A21D13/28 , A21D13/60 , A23G3/343 , A23P20/10 , A23P20/105
摘要： The gloss of iced frozen baked goods once thawed, is enhanced by coating the baked goods with shellac prior to freezing.

7. 发明申请

US20090246330A1 ANTI-SCUFF COATING FOR CHOCOLATE 审中-公开
标题翻译：用于巧克力的防雾涂料
公开(公告)号：US20090246330A1
公开(公告)日：2009-10-01
申请号：US12294290
申请日：2007-03-26
申请人： Bin Zhong , Margo McWeeney , Stephen A. Santos , Alan McGregor
发明人： Bin Zhong , Margo McWeeney , Stephen A. Santos , Alan McGregor
IPC分类号： A23G1/54 , A23L1/275 , A23L3/28
CPC分类号： A23P20/105 , A23G1/305 , A23G1/54 , A23G2200/00
摘要： Provided herein are methods and compositions for forming a coating on the external surface of a solid chocolate or chocolate-coated product. The method comprises applying at least one layer of a coating composition comprising a solvent selected from water, ethanol, and isopropanol, or any combination thereof and one or more film forming agents to the external surface of the product, and then drying the coating composition to provide a dried coating or film on the external surface of the chocolate. The dried coating renders the external surface of the chocolate more resistant to abrasion or scuffing during processing, packaging, storage, and/or transport. The coating composition of the present invention cures or dries in 30 minutes or less. In certain embodiments, the film or coating cures in 15 minutes or less. In certain embodiments, the film or coating cures in 10 minutes or less.
摘要翻译：本文提供了在固体巧克力或巧克力涂层产品的外表面上形成涂层的方法和组合物。该方法包括将至少一层包含选自水，乙醇和异丙醇的溶剂或其任何组合和一种或多种成膜剂的涂料组合物涂覆到产品的外表面上，然后将涂料组合物干燥至在巧克力的外表面上提供干燥的涂层或薄膜。干燥的涂层使得巧克力的外表面在加工，包装，储存和/或运输过程中更耐磨损或磨损。本发明的涂料组合物在30分钟以内固化或干燥。在某些实施方案中，薄膜或涂层在15分钟或更短时间内固化。在某些实施方案中，膜或涂层在10分钟或更短时间内固化。

8. 发明申请

US20190175602A1 HETEROCYCLE-SUBSTITUTED TETRACYCLIC COMPOUNDS AND METHODS OF USE THEREOF FOR THE TREATMENT OF VIRAL DISEASES 审中-公开
公开(公告)号：US20190175602A1
公开(公告)日：2019-06-13
申请号：US16326039
申请日：2017-08-14
申请人： Wensheng Yu , LING Tong , Joseph A. Koziowski , Craig: A Coburn , De-yi J. Yang , Deyou Sha , Jae-Hun. Kim , Michael Dwyer , Kartik M. Keertikar , Bin Hu , Bin Zhong , Jinglai Hao , Dahai Wang
发明人： Wensheng Yu , LING Tong , Joseph A. Koziowski , Craig: A Coburn , De-yi J. Yang , Deyou Sha , Jae-Hun. Kim , Michael Dwyer , Kartik M. Keertikar , Bin Hu , Bin Zhong , Jinglai Hao , Dahai Wang
IPC分类号： A61K31/5365 , C07D498/04 , A61P31/14 , A61K31/4995 , C07D519/00
摘要： The present invention relates to novel Heterocycle-Substituted Tetracyclic Compounds of Formula (I): (I) and pharmaceutically acceptable salts thereof, wherein A, A′, R2 R3 and R5 are as defined herein. The present invention also relates to compositions comprising at least one Heterocycle-Substituted Tetra-cyclic Compound, and methods of using the Heterocycle-Substituted Tetracyclic Compounds for treating or preventing HCV infection in a patient.

9. 发明申请

US20170073354A1 PIPERAZINE DERIVATIVES AS HIV PROTEASE INHIBITORS 审中-公开
标题翻译：作为HIV蛋白酶抑制剂的哌嗪衍生物
公开(公告)号：US20170073354A1
公开(公告)日：2017-03-16
申请号：US15124635
申请日：2015-03-06
申请人： Jurgen SCHULZ , Peter D. WILLIAMS , John A. MCCAULEY , Christopher J. BUNGARD , David Jonathan BENNETT , Sherman T. WADDELL , Gregori J. MORRIELLO , Lehua CHANG , Michael P. DWYER , Katharine M. HOLLOWAY , Alejandro CRESPO , Xin-Jie CHU , Catherine WISCOUNT , Marie H. LOUGHRAN , Jesse J. MANIKOWSKI , Kartik M. KEERTIKAR , Bin HU , Bin ZHONG , Tao JI , Merck Sharp & Dohme Corp. , MSD R&D (China) Co., Ltd.
发明人： Peter D. Williams , John A. McCauley , Christopher J. Bungard , David Jonathan Bennett , Sherman T. Waddell , Gregori J. Morriello , Lehua Chang , Michael P. Dwyer , M. Katharine Holloway , Alejandro Crespo , Xin-Jie Chu , Catherine Wiscount , H. Marie Loughran , Jesse J. Manikowski , Jurgen Schulz , Kartik M. Keertikar , Bin Hu , Bin Zhong , Tao Ji
IPC分类号： C07D513/08 , A61K31/554 , A61K45/06
CPC分类号： C07D513/08 , A61K31/554 , A61K45/06
摘要： The present invention is directed to compounds of Formula I pharmaceutical compositions comprising the same, and their use in the inhibition of HIV protease, the inhibition of HIV replication, the prophylaxis of infection by HIV, the treatment of infection by HIV, and the prophylaxis, treatment, and delay in the onset or progression of AIDS.
摘要翻译：本发明涉及含有该化合物的式I药物组合物的化合物及其在抑制HIV蛋白酶，抑制HIV复制，预防HIV感染，HIV感染治疗和预防，治疗和延迟艾滋病的发病或进展。

10. 发明申请

US20120083483A1 INHIBITORS OF HEPATITIS C VIRUS REPLICATION 有权
标题翻译： HEPATITIS C VIRUS REPLICATION的抑制剂
公开(公告)号：US20120083483A1
公开(公告)日：2012-04-05
申请号：US13260684
申请日：2010-03-25
申请人： Craig A. Coburn , John A. McCauley , Steven W. Ludmerer , Kun Liu , Joseph P. Vacca , Hao Wu , Bin Hu , Richard Soll , Fei Sun , Xinghai Wang , Man Yan , Chengren Zhang , Mingwei Zheng , Bin Zhong , Jian Zhu
发明人： Craig A. Coburn , John A. McCauley , Steven W. Ludmerer , Kun Liu , Joseph P. Vacca , Hao Wu , Bin Hu , Richard Soll , Fei Sun , Xinghai Wang , Man Yan , Chengren Zhang , Mingwei Zheng , Bin Zhong , Jian Zhu
IPC分类号： A61K31/553
CPC分类号： C07D498/04 , A61K31/4025 , A61K31/404 , A61K31/4178 , A61K31/4184 , A61K31/423 , A61K31/437 , A61K31/4439 , A61K31/4985 , A61K31/506 , A61K31/5365 , A61K31/5377 , A61K31/5383 , A61K31/553 , A61K38/05 , A61K38/06 , A61K45/06 , C07D401/14 , C07D403/12 , C07D403/14 , C07D405/12 , C07D405/14 , C07D409/14 , C07D413/14 , C07D471/04 , C07D487/04 , C07D498/10 , C07K5/06 , C07K5/08
摘要： The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5A inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5A activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.
摘要翻译：本发明涉及可用作丙型肝炎病毒（HCV）NS5A抑制剂，这种化合物的合成以及这些化合物用于抑制HCV NS5A活性用于治疗或预防HCV感染的用途的式（I）化合物和抑制基于细胞的系统中的HCV病毒复制和/或病毒生产。

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