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1. 发明授权

US5279618A Process and kit for dyeing hair 失效
标题翻译：毛发染色工艺和成套工具
公开(公告)号：US5279618A
公开(公告)日：1994-01-18
申请号：US923078
申请日：1992-07-31
申请人： Giuseppe Prota , Leszek Wolfram , Gottfried Wenke
发明人： Giuseppe Prota , Leszek Wolfram , Gottfried Wenke
IPC分类号： A61K8/00 , A61K20060101 , A61K8/20 , A61K8/24 , A61K8/33 , A61K8/41 , A61K8/44 , A61K8/49 , A61Q5/10 , A61K7/13
CPC分类号： A61K8/44 , A61Q5/10
摘要： A process for dyeing hair by preparing and thereafter applying to the hair an aqueous reaction medium comprising dopa and an oxidant, said aqueous reaction medium further containing at least one hair dyeing agent selected from the group consisting of primary intermediates and couplers and also containing a buffer to maintain the pH in the range from 6 to 10 during the reaction, and removing said aqueous reaction medium from the hair within about one hour following its preparation.
摘要翻译：通过制备毛发以及其后向包含多巴和氧化剂的水性反应介质施加染发毛发的方法，所述水性反应介质还包含至少一种选自主要中间体和成色剂的染发剂，并且还含有缓冲液以在反应期间将pH保持在6至10的范围内，并且在其制备后约1小时内从毛发中除去所述水性反应介质。

2. 发明授权

US5704949A Process for the manufacture of a hair dye product containing 5,6-dihydroxyindole 失效
标题翻译：用于制造含有5,6-二羟基吲哚的染发剂的方法
公开(公告)号：US5704949A
公开(公告)日：1998-01-06
申请号：US603953
申请日：1996-02-16
申请人： Giuseppe Prota , Gottfried Wenke , Leszek Wolfram
发明人： Giuseppe Prota , Gottfried Wenke , Leszek Wolfram
IPC分类号： A61K8/49 , A61Q5/10 , A61K7/13
CPC分类号： A61Q5/10 , A61K8/492
摘要： The present invention is directed to the preparation of an aqueous hair dyeing composition containing an effective hair dyeing amount--at least 2 mg/ml--5,6-dihydroxyindole (DHI). An aqueous hair dyeing composition is produced by reacting under essentially anaerobic conditions dopa or a salt thereof with an alkali metal ferricyanide oxidant in an aqueous reaction medium to obtain dopachrome, and permitting the dopachrome to undergo rearrangement in the aqueous medium to form 5,6-dihydroxyindole, said rearrangement being conducted in the substantial absence of oxidant, the aqueous medium being buffered by sufficient buffering agent to maintain a pH of from about 4.5 to about 9 for the reaction medium throughout the series of reactions that take place thereafter, removing the ferrocyanide species present in the aqueous system, and lastly, charging the composition into a suitable container.
摘要翻译：本发明涉及含有有效染发剂量至少2mg / ml-5,6-二羟基吲哚（DHI）的含水染发组合物的制备。通过在基本上厌氧条件下使多巴或其盐与碱金属铁氰化物氧化剂在水性反应介质中反应来制备水性染发组合物，以获得多巴色素，并允许多巴色素在水性介质中重排以形成5,6- 所述重排在实质上不存在氧化剂的情况下进行，所述水性介质通过足够的缓冲剂缓冲，以在其后发生的一系列反应中为反应介质保持pH为约4.5至约9，除去亚铁氰化物存在于水体系中的物质，最后，将组合物装入合适的容器中。

3. 发明授权

US5279617A Process and kit for dyeing hair 失效
标题翻译：毛发染色工艺和成套工具
公开(公告)号：US5279617A
公开(公告)日：1994-01-18
申请号：US909371
申请日：1992-07-13
申请人： Giuseppe Prota , Leszek Wolfram , Gottfried Wenke
发明人： Giuseppe Prota , Leszek Wolfram , Gottfried Wenke
IPC分类号： A61K20060101 , A61K7/13
CPC分类号： A61K8/44 , A61Q5/10
摘要： A process for dyeing hair by preparing and thereafter applying to the hair an aqueous reaction medium comprising a substituted dopa species and an oxidant which is a ferricyanide salt, said aqueous reaction medium further containing a buffer to maintain the pH in the range from 6 to 10 during the reaction, and removing said aqueous reaction medium from the hair within about one hour following its preparation.
摘要翻译：通过制备毛发以及其后将包含取代的多巴物质和作为铁氰化物盐的氧化剂的水性反应介质施用于头发来染色毛发的方法，所述水性反应介质还含有缓冲液以将pH维持在6至10的范围内并且在其制备后约1小时内从毛发中除去所述水性反应介质。

4. 发明授权

US5032138A Chlorites as oxidants in hair coloring 失效
标题翻译：亚氯酸盐作为毛发着色中的氧化剂
公开(公告)号：US5032138A
公开(公告)日：1991-07-16
申请号：US355950
申请日：1989-05-23
申请人： Leszek Wolfram , Thomas Schultz , Alice Mayer , Keith Brown
发明人： Leszek Wolfram , Thomas Schultz , Alice Mayer , Keith Brown
IPC分类号： A61K8/00 , A45D20060101 , A61K20060101 , A61K8/20 , A61Q5/10 , C01B20060101 , C01B11/10 , C07C39/07 , C07C39/38 , C07C211/51 , C07C215/76 , D06P3/08
CPC分类号： A61K8/20 , A61Q5/10
摘要： The invention provides compositions and methods for oxidative hair dyeing utilizing a chlorite salt as the oxidizing agent.

5. 发明授权

US4968497A Skin tanning composition and method 失效
标题翻译：皮肤晒黑组合物和方法
公开(公告)号：US4968497A
公开(公告)日：1990-11-06
申请号：US237123
申请日：1988-08-26
申请人： Leszek Wolfram , Alexander C. Chan , Thomas M. Schultz , Bryan P. Murphy
发明人： Leszek Wolfram , Alexander C. Chan , Thomas M. Schultz , Bryan P. Murphy
IPC分类号： A61K8/00 , A61K8/34 , A61K8/44 , A61K8/49 , A61Q17/04 , A61Q19/04
CPC分类号： A61Q19/04 , A61K8/44 , A61K8/492 , Y10S514/937
摘要： The present invention relates to a method of imparting a controlled tanning of skin by treating the skin with an aqueous medium containing melanin or a precursor of melanin.

6. 发明授权

US5665336A Acidic post-treatment of hair dyed with dihydroxyindole 失效
标题翻译：酸性后处理用二羟基吲哚染色的头发
公开(公告)号：US5665336A
公开(公告)日：1997-09-09
申请号：US517179
申请日：1995-08-21
申请人： Leszek Wolfram
发明人： Leszek Wolfram
IPC分类号： A61K8/49 , A61Q5/10 , A61K7/06 , A61K7/13
CPC分类号： A61K8/492 , A61Q5/10
摘要： A process for altering the color of hair that has been dyed with dihydroxyindole comprising the steps of treating the dyed hair with an acidic solution for an effective amount of time and rinsing the treated hair.
摘要翻译：用二羟基吲哚染色的毛发颜色的改变方法，包括用酸性溶液处理染色毛发达一段有效时间并冲洗经处理的毛发的步骤。

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