专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US06750337B2 Couplers for use in oxidative hair dyeing 有权
标题翻译：用于氧化染发剂的成色剂
公开(公告)号：US06750337B2
公开(公告)日：2004-06-15
申请号：US10052362
申请日：2002-01-18
申请人： Mu-Ill Lim , Yuh-Guo Pan , Gottfried Wenke
发明人： Mu-Ill Lim , Yuh-Guo Pan , Gottfried Wenke
IPC分类号： C07D27910
CPC分类号： C07C217/84 , A61K8/415 , A61K8/416 , A61K8/49 , A61K8/4906 , A61K8/4913 , A61K8/4926 , A61K8/494 , A61Q5/10 , C07C2601/14
摘要： Couplers for hair coloring compositions for oxidative dyeing of hair are compounds of the formula (1): wherein X is selected from halogen and R5SO4 where the halogen is preferably Cl, Br or I; R, R1 and R2 are each individually selected from C1 to C22 alkyl and C1 to C22 mono or dihydroxyalkyl, or two of R, R1 and R2 together with the nitrogen atom to which they are attached form a C3 to C6 saturated or unsaturated ring optionally containing in the ring one or more additional hetero atoms selected from O, S and N atoms; R3 and R 4 are each individually selected from C1 to C6 alkyl, C1 to C6 hydroxyalkyl, C1 to C6 alkoxy, C1 to C6 aminoalkyl or R3 and R4 together form a C1 to C5 alkylene group; and R5 is selected from C1 to C22 alkyl and C1 to C22 mono or dihydroxyalkyl.
摘要翻译：用于头发氧化染色的染发组合物的成色剂是式（1）的化合物：其中X选自卤素和R 5 SO 4，其中卤素优选为Cl，Br或I; R 1，R 2和R 2各自独立地选自C 1至C 22烷基和C 1至C 22单或二羟基烷基，或者R 1，R 2和R 2中的两个与它们的氮原子一起连接形成任选地在环中含有一个或多个选自O，S和N原子的另外的杂原子的C 3至C 6饱和或不饱和环; R 3和R 4各自独立地选自C 1至C 6烷基，C 1至C 6羟基烷基，C 1至C 6烷氧基，C 1至C 6氨基烷基或R 3和R 4一起形成C 1至C 5亚烷基组; 并且R 5选自C 1至C 22烷基和C 1至C 22单或二羟基烷基。

2. 发明授权

US5961991A Melanoquaternary compounds and their use as hair dyes and for skin treatment 失效
标题翻译：梅拉诺季铵化合物及其作为染发剂和用于皮肤治疗的用途
公开(公告)号：US5961991A
公开(公告)日：1999-10-05
申请号：US873386
申请日：1997-06-11
申请人： Gottfried Wenke , Giuseppe Prota
发明人： Gottfried Wenke , Giuseppe Prota
IPC分类号： A61K8/41 , A61K8/49 , A61K8/72 , A61Q5/06 , A61Q5/10 , A61Q17/04 , A61Q19/04 , A61K7/48
CPC分类号： A61Q19/04 , A61K8/416 , A61K8/492 , A61K8/72 , A61Q17/04 , A61Q5/065 , A61Q5/10 , A61K2800/57
摘要： Water soluble, cationic products useful as hair colorants or for the treatment of skin which are esters or amides formed by reaction of melanin and a quaternary salt containing a reactive amino or hydroxyl group, as well as compositions containing them and methods of using such products to color hair or treat skin are described.
摘要翻译：可用作头发着色剂的水溶性阳离子产品或用于治疗由黑色素和含有反应性氨基或羟基的季盐形成的酯或酰胺的皮肤，以及含有它们的组合物以及使用这些产品的方法描述了彩色头发或治疗皮肤。

3. 发明授权

US5827330A Synthesis of quarternary melanin compounds and their use as hair dyes or for skin treatment 失效
标题翻译：合成季铵黑色素化合物及其用作染发剂或用于皮肤治疗
公开(公告)号：US5827330A
公开(公告)日：1998-10-27
申请号：US874154
申请日：1997-06-13
申请人： Gottfried Wenke , Giuseppe Prota
发明人： Gottfried Wenke , Giuseppe Prota
IPC分类号： A61K8/00 , A61K8/40 , A61K8/49 , A61K8/72 , A61Q5/06 , A61Q5/10 , A61Q19/00 , C07D209/04 , C07D209/18 , C07D209/42 , A61K7/13 , A61K7/42
CPC分类号： A61Q5/10 , A61K8/492 , A61K8/72 , A61Q5/065
摘要： Water soluble, cationic products useful as hair colorants or for the treatment of skin which are esters or amides formed by reaction of melanin and a quaternary salt containing a reactive amino or hydroxyl group, as well as compositions containing them and methods of using such products to color hair or treat skin are described.
摘要翻译：可用作头发着色剂的水溶性阳离子产品或用于治疗由黑色素和含有反应性氨基或羟基的季盐形成的酯或酰胺的皮肤，以及含有它们的组合物以及使用这些产品的方法描述了彩色头发或治疗皮肤。

4. 发明授权

US5704949A Process for the manufacture of a hair dye product containing 5,6-dihydroxyindole 失效
标题翻译：用于制造含有5,6-二羟基吲哚的染发剂的方法
公开(公告)号：US5704949A
公开(公告)日：1998-01-06
申请号：US603953
申请日：1996-02-16
申请人： Giuseppe Prota , Gottfried Wenke , Leszek Wolfram
发明人： Giuseppe Prota , Gottfried Wenke , Leszek Wolfram
IPC分类号： A61K8/49 , A61Q5/10 , A61K7/13
CPC分类号： A61Q5/10 , A61K8/492
摘要： The present invention is directed to the preparation of an aqueous hair dyeing composition containing an effective hair dyeing amount--at least 2 mg/ml--5,6-dihydroxyindole (DHI). An aqueous hair dyeing composition is produced by reacting under essentially anaerobic conditions dopa or a salt thereof with an alkali metal ferricyanide oxidant in an aqueous reaction medium to obtain dopachrome, and permitting the dopachrome to undergo rearrangement in the aqueous medium to form 5,6-dihydroxyindole, said rearrangement being conducted in the substantial absence of oxidant, the aqueous medium being buffered by sufficient buffering agent to maintain a pH of from about 4.5 to about 9 for the reaction medium throughout the series of reactions that take place thereafter, removing the ferrocyanide species present in the aqueous system, and lastly, charging the composition into a suitable container.
摘要翻译：本发明涉及含有有效染发剂量至少2mg / ml-5,6-二羟基吲哚（DHI）的含水染发组合物的制备。通过在基本上厌氧条件下使多巴或其盐与碱金属铁氰化物氧化剂在水性反应介质中反应来制备水性染发组合物，以获得多巴色素，并允许多巴色素在水性介质中重排以形成5,6- 所述重排在实质上不存在氧化剂的情况下进行，所述水性介质通过足够的缓冲剂缓冲，以在其后发生的一系列反应中为反应介质保持pH为约4.5至约9，除去亚铁氰化物存在于水体系中的物质，最后，将组合物装入合适的容器中。

5. 发明授权

US5279617A Process and kit for dyeing hair 失效
标题翻译：毛发染色工艺和成套工具
公开(公告)号：US5279617A
公开(公告)日：1994-01-18
申请号：US909371
申请日：1992-07-13
申请人： Giuseppe Prota , Leszek Wolfram , Gottfried Wenke
发明人： Giuseppe Prota , Leszek Wolfram , Gottfried Wenke
IPC分类号： A61K20060101 , A61K7/13
CPC分类号： A61K8/44 , A61Q5/10
摘要： A process for dyeing hair by preparing and thereafter applying to the hair an aqueous reaction medium comprising a substituted dopa species and an oxidant which is a ferricyanide salt, said aqueous reaction medium further containing a buffer to maintain the pH in the range from 6 to 10 during the reaction, and removing said aqueous reaction medium from the hair within about one hour following its preparation.
摘要翻译：通过制备毛发以及其后将包含取代的多巴物质和作为铁氰化物盐的氧化剂的水性反应介质施用于头发来染色毛发的方法，所述水性反应介质还含有缓冲液以将pH维持在6至10的范围内并且在其制备后约1小时内从毛发中除去所述水性反应介质。

6. 发明授权

US06379399B1 Oxidation hair dyeing systems and process for providing more equalized coloration on new and old growth hair 失效
标题翻译：氧化染发系统和在新旧生长发上提供更均匀着色的方法
公开(公告)号：US06379399B1
公开(公告)日：2002-04-30
申请号：US09504818
申请日：2000-02-16
申请人： Gottfried Wenke , Michael Y. M. Wong
发明人： Gottfried Wenke , Michael Y. M. Wong
IPC分类号： A61K713
CPC分类号： A61K8/411 , A61K8/415 , A61K8/4926 , A61Q5/10
摘要： Oxidative hair dyeing systems are provided that are “root seeking”, i.e., which produce more intense initial coloration on new growth, less porous hair compared to the initial coloration produced in older, damaged, more porous hair. More equalized coloration along the shaft of hair can be obtained with the “root seeking” dyeing products.
摘要翻译：提供了氧化染发系统，其是“根本寻求”，即在新生长时产生更强烈的初始着色，与在较老的，损坏的，更多孔的头发中产生的初始着色相比，具有较少的多孔毛发。可以通过“寻根”染色产品获得沿毛发轴更均衡的着色。

7. 发明授权

US5792220A Dyeing hair with melanin procursors in the presence of iodate and peroxide 失效
标题翻译：在碘酸盐和过氧化物存在下，用黑色素前体染色头发
公开(公告)号：US5792220A
公开(公告)日：1998-08-11
申请号：US857632
申请日：1997-05-16
申请人： Gottfried Wenke , Giuseppe Prota
发明人： Gottfried Wenke , Giuseppe Prota
IPC分类号： A61K8/49 , A61Q5/10 , A61K7/13
CPC分类号： A61Q5/10 , A61K8/492
摘要： The present invention concerns improved processes for dyeing keratinous fibers especially hair on the human scalp using a two-step oxidation process for the oxidation of the melanin precursors 5,6-dihydroxyindoline (DHIN), 5,6-dihydroxyindole (DHI), and derivatives thereof such as 5,6-dihydroxyindole-2-carboxylic acid (DHICA).
摘要翻译：本发明涉及使用用于氧化黑色素前体5,6-二羟基二氢吲哚（DHIN），5,6-二羟基吲哚（DHI）和衍生物的两步氧化方法对人类头皮上的角质纤维特别是毛发染色的改进方法例如5,6-二羟基吲哚-2-羧酸（DHICA）。

8. 发明授权

US5702712A Melanoquaternary compounds and their use as hair dyes and for skin treatment 失效
标题翻译：梅拉诺季铵化合物及其作为染发剂和用于皮肤治疗的用途
公开(公告)号：US5702712A
公开(公告)日：1997-12-30
申请号：US568056
申请日：1995-12-06
申请人： Gottfried Wenke , Giuseppe Prota
发明人： Gottfried Wenke , Giuseppe Prota
IPC分类号： A61K8/41 , A61K8/49 , A61K8/72 , A61Q5/06 , A61Q5/10 , A61Q17/04 , A61Q19/04 , A61K7/48
CPC分类号： A61Q19/04 , A61K8/416 , A61K8/492 , A61K8/72 , A61Q17/04 , A61Q5/065 , A61Q5/10 , A61K2800/57
摘要： Water soluble, cationic products useful as hair colorants or for the treatment of skin which are esters or amides formed by reaction of melanin and a quaternary salt containing a reactive amino or hydroxyl group, as well as compositions containing them and methods of using such products to color hair or treat skin are described.
摘要翻译：可用作头发着色剂的水溶性阳离子产品或用于治疗由黑色素和含有反应性氨基或羟基的季盐形成的酯或酰胺的皮肤，以及含有它们的组合物以及使用这些产品的方法描述了彩色头发或治疗皮肤。

9. 发明授权

US5486619A Method of producing DAI from DOPA, using one reaction vessel 失效
标题翻译：使用一个反应容器从DOPA生产DAI的方法
公开(公告)号：US5486619A
公开(公告)日：1996-01-23
申请号：US235763
申请日：1994-04-29
申请人： Gottfried Wenke , Yuh-Guo Pan , Mu-Ill Lim , Linas Stasaitis
发明人： Gottfried Wenke , Yuh-Guo Pan , Mu-Ill Lim , Linas Stasaitis
IPC分类号： C07D209/08
CPC分类号： C07D209/08
摘要： A method of producing and isolating 5,6-diacetoxyindole (DAI) in a single reaction vessel comprising the following steps:(a) preparing a first solution comprising dopa, water and a solubilizing agent selected from the group consisting of an acid having a pk.sub.a value equal to or less than 4 and a first base having a pk.sub.b value equal to or greater than 10;(b) preparing a second solution comprising an oxidant, a buffer and water;(c) mixing the first and second solutions to form a combined solution which is rendered oxygen-free and has a pH of from about 6 to about 9;(d) stirring the combined solution in an inert atmosphere until 5,6-dihydroxyindole (DHI) is substantially completely formed;(e) adding a derivatizing agent and a second base to the combined solution to form a final solution;(f) stirring the final solution until the DHI is substantially fully consumed;(g) cooling the final solution to precipitate DAI;(h) isolating the precipitated DAI.
摘要翻译：一种在单个反应容器中生产和分离5,6-二乙酰氧基吲哚（DAI）的方法，包括以下步骤：（a）制备包含多巴，水和增溶剂的第一溶液，所述第一溶液选自具有pka 值等于或小于4，以及pkb值等于或大于10的第一碱基; （b）制备包含氧化剂，缓冲剂和水的第二溶液; （c）混合第一和第二溶液以形成无氧的并具有约6至约9的pH的组合溶液; （d）在惰性气氛中搅拌合并的溶液直到5,6-二羟基吲哚（DHI）基本上完全形成; （e）向组合溶液中加入衍生剂和第二碱以形成最终溶液; （f）搅拌最终溶液直到DHI基本上完全消耗; （g）冷却最终溶液以沉淀DAI; （h）分离析出的DAI。

10. 发明授权

US5441542A Process and kit for post-oxidative treatment of permanently dyed hair 失效
标题翻译：永久染色头发后氧化处理的方法和试剂盒
公开(公告)号：US5441542A
公开(公告)日：1995-08-15
申请号：US174487
申请日：1993-12-27
申请人： Giuseppe Prota , Gottfried Wenke
发明人： Giuseppe Prota , Gottfried Wenke
IPC分类号： A61K7/13
CPC分类号： A61K8/44 , A61Q5/10
摘要： A process for increasing the amount of melanin formation following hair dyeing by ferricyanide oxidation of a dopa species hair colorant utilizing a post-oxidant such as sodium periodate at a controlled pH and compositions and kits for use in the process.
摘要翻译：通过在受控pH下使用后氧化剂如高碘酸钠的多巴物质着色剂，通过铁氰化物氧化来增加黑色素形成量的方法以及用于该方法的组合物和试剂盒的方法。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式