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1. 发明申请

US20050273088A1 Myopia correction enhancing biodynamic ablation 审中-公开
标题翻译：近视矫正增强生物动力学消融
公开(公告)号：US20050273088A1
公开(公告)日：2005-12-08
申请号：US10519368
申请日：2003-06-26
申请人： Gerhard Youssefi , Friedrich Moritz
发明人： Gerhard Youssefi , Friedrich Moritz
IPC分类号： A61F9/007 , A61B18/20 , A61F9/01
CPC分类号： A61F9/008 , A61F9/00804 , A61F9/00817 , A61F2009/00857 , A61F2009/00872
摘要： This invention is directed to a method for providing a LASIK or a LASEK myopia vision correction, and to a medium that has stored therein an instruction for directing a laser vision correcting laser platform to deliver a controlled biodynamic ablation according to the invention. A known biodynamic response of the eye is induced by performing a controlled laser ablation in a cornea of the eye outside of an optical zone for the nominal ablation in a laser vision correction surgery. An ablation ring, or portion thereof, outside of the optical zone produces a biodynamic flattening of the central region of the cornea which in turn provides for a decreased depth of volumetric ablation to correct a myopic refractive defect of the eye. Such controlled biodynamic flattening may provide the opportunity for laser vision correction in patients whose corneas would otherwise be too thin post-operatively to warrant laser vision correction.
摘要翻译：本发明涉及一种用于提供LASIK或LASEK近视视力矫正的方法，以及存储有根据本发明的用于引导激光视力矫正激光平台传送受控生物动力学消融的指令的介质。通过在激光视力矫正手术中的用于标称消融的光学区域外部的眼睛的角膜中进行受控激光烧蚀来诱导眼睛的已知生物动力学响应。在光学区域外部的消融环或其部分产生角膜中心区域的生物动力学平坦化，其进而降低体积消融的深度以校正眼睛的近视屈光不良。这种受控的生物动力学平整可以为患者提供激光视力矫正的机会，其角膜否则在手术后会太薄，以保证激光视力矫正。

2. 发明授权

US07029119B2 Objective manifest refraction 有权
$Objective manifest refraction$
公开(公告)号：US07029119B2
公开(公告)日：2006-04-18
申请号：US10972096
申请日：2004-10-22
申请人： Gerhard Youssefi , Friedrich Moritz
发明人： Gerhard Youssefi , Friedrich Moritz
IPC分类号： A61B3/10 , A61B3/00
CPC分类号： A61B3/0025 , G06F19/00
摘要： An method for providing an objective manifest refraction of a patient's eye includes obtaining at least fourth-order Zernike wavefront aberration information, fitting a second-order only polynomial to the at least fourth-order data, and using this information to predict the patient's manifest refraction with an accuracy approaching the patient's subjective manifest refraction. A method is also described for prescribing an accurate vision correction based upon the objective manifest refraction. A display according to the invention includes higher-order wavefront aberrations, lower order wavefront aberrations, numerical indicia of predicted manifest refraction, and images of qualitative assessments of a patient's vision quality. A device for obtaining an objective manifest refraction is described.

3. 发明申请

US20080228177A1 System and Method for Correction of Ophthalmic Refractive Errors 审中-公开
$System and Method for Correction of Ophthalmic Refractive Errors$
标题翻译：矫正眼科屈光不正的系统和方法
公开(公告)号：US20080228177A1
公开(公告)日：2008-09-18
申请号：US12092899
申请日：2006-10-12
申请人： Friedrich Moritz , Gerhard Youssefi
发明人： Friedrich Moritz , Gerhard Youssefi
IPC分类号： A61F9/01 , A61B3/10
CPC分类号： A61F9/008 , A61F9/007 , A61F9/00806
摘要： The present invention relates to a system and a method for calculating a course of refractive treatment for correcting a refractive error of a patient's eye. It is based on the concept to combine at least a first treatment which provides an overcorrection of the intended correction with at least a second treatment which corrects said overcorrection.
摘要翻译：本发明涉及一种用于计算用于矫正患者眼睛屈光不正的折射治疗过程的系统和方法。这是基于将至少第一种处理结合起来的概念，该第一种处理提供预期校正的过度校正以及至少第二种处理，其校正所述过度校正。

4. 发明申请

US20070161972A1 Method, system and algorithm related to treatment planning for vision correction 审中-公开
标题翻译：与视力矫正治疗计划相关的方法，系统和算法
公开(公告)号：US20070161972A1
公开(公告)日：2007-07-12
申请号：US10550438
申请日：2004-04-12
申请人： Craig Felberg , Robin Hughes , Rupert Veith , Michael Johnson , Florian Dambacher , Arne Matthaus , Gerhard Youssefi , Friedrich Moritz
发明人： Craig Felberg , Robin Hughes , Rupert Veith , Michael Johnson , Florian Dambacher , Arne Matthaus , Gerhard Youssefi , Friedrich Moritz
IPC分类号： A61B18/18 , A61B3/00
CPC分类号： A61F9/00806 , A61B3/103 , A61B3/107 , A61F2009/00846 , A61F2009/00857 , A61F2009/00859 , A61F2009/00872 , A61F2009/0088 , A61F2009/00882 , G06F19/3481
摘要： The invention is directed to a system and methods for automatically determining a multiple number of viable treatment plans for correcting a patient's vision via photoablative refractive surgery. Embodiments of the invention rely on selected various diagnostic input about the patient's eye to classify the eye as being particularly suitable for treatment by several different treatment algorithms. The invention is further directed to the simultaneous presentation of various treatment plans based upon selected input data and available treatment algorithms that can be reviewed, modified, and ultimately selected for application. A system embodiment according to the invention includes a component for receiving the diagnostic input data about the patient's vision, for analyzing the input data and determining the potentially usable treatment algorithms, and for processing the potentially usable treatment algorithms based upon the input data, and a component for displaying the multilevel graphical user interface which facilitates review, modification, and selection of viable treatment plans for correcting the patient's vision. The system is further operably associated with a storage medium for storing calculated and selected treatment plans which include executable instructions for a photoablative laser component of the system to deliver a selected treatment plan to the patient's eye.
摘要翻译：本发明涉及一种系统和方法，用于通过光烧伤性屈光手术来自动确定用于校正患者视力的多个可行治疗计划。本发明的实施例依赖于关于患者眼睛的所选择的各种诊断输入来将眼睛分类为特别适合于通过若干不同的治疗算法进行治疗。本发明进一步涉及基于所选择的输入数据和可被审查，修改和最终选择用于应用的可用治疗算法来同时呈现各种治疗计划。根据本发明的系统实施例包括用于接收关于患者视力的诊断输入数据的组件，用于分析输入数据并确定潜在可用的治疗算法，以及基于输入数据处理潜在可用的治疗算法，以及用于显示多级图形用户界面的组件，其便于查看，修改和选择用于校正患者视力的可行治疗计划。该系统进一步可操作地与用于存储计算和选择的治疗计划的存储介质相关联，所述治疗计划包括用于系统的光消融激光组件的可执行指令，以将选定的治疗计划传递给患者的眼睛。

5. 发明申请

US20070032782A1 Method and apparatus for eye alignment 审中-公开
标题翻译：眼睛对齐的方法和装置
公开(公告)号：US20070032782A1
公开(公告)日：2007-02-08
申请号：US10549220
申请日：2004-02-18
申请人： Gerhard Youssefi , Friedrich Moritz
发明人： Gerhard Youssefi , Friedrich Moritz
IPC分类号： A61F9/008 , A61B18/18
CPC分类号： A61F9/008 , A61B3/113 , A61F2009/00846 , A61F2009/00872 , G01B9/02091
摘要： In an ophthalmic laser system preferably intended for photoablative refractive surgery, a component apparatus that is preferably an optical coherence tomography device for measuring corneal pachymetry makes its measurement when the First and Second Purkinje reflections of the OCT probe beam are detected, otherwise, the reflection signal is not strong enough to enable the OCT measurement. The beam axis of the therapeutic laser of the system is co-aligned with the OCT-prbbe beam. When the First and Second Purkinje reflections of the OCT probe beam are detected, a signal is generated by the OCT device and sent to the eye tracker component of the system to engage the eye tracker operation. This allows for objective, automatic engagement of the eye tracker and alignment of the patient's optical axis to the treatment axis or a diagnostic beam axis.
摘要翻译：在优选用于光烧伤性屈光手术的眼科激光系统中，优选地，用于测量角膜厚度测量的光学相干断层摄影装置的分量装置在检测到OCT探针光束的第一和第二浦肯野反射时进行测量，否则，反射信号不够强大，不能进行OCT测量。系统的治疗激光束的光束轴与OCT-prbbe光束共同对准。当检测到OCT探测光束的第一次和第二次浦肯野反射时，由OCT装置产生信号并将其发送到系统的眼睛跟踪器部件以进行眼动仪操作。这允许眼睛跟踪器的客观的自动接合和患者的光轴对准治疗轴或诊断光束轴。

6. 发明授权

US10716706B2 System and method for performing lens fragmentation 有权
公开(公告)号：US10716706B2
公开(公告)日：2020-07-21
申请号：US13436352
申请日：2012-03-30
申请人： Frieder Loesel , Jochen Kandulla , Friedrich Moritz , Gwillem Mosedale , Holger Schlueter , Roland Toennies , Gerhard Youssefi , David Haydn Mordaunt
发明人： Frieder Loesel , Jochen Kandulla , Friedrich Moritz , Gwillem Mosedale , Holger Schlueter , Roland Toennies , Gerhard Youssefi , David Haydn Mordaunt
IPC分类号： A61F9/008
摘要： A system and method are provided for fragmenting a crystalline lens, to facilitate its removal from the lens bag during an ophthalmic laser surgery. First, a predetermined pattern is used to make Laser Induced Optical Breakdown (LIOB) cuts that section the lens into asymmetrical, operational segments. At least one operational segment is then selected and softened with a plurality of compact LIOB cuts. Once softened, the selected segment is aspirated. The remaining operational segments are then subsequently removed. During a procedure, an imaging unit can monitor movements of the lens bag to ensure proper placement of the LIOB cuts on the lens.

7. 发明申请

US20130317488A1 System and Method for Correction of Ophthalmic Refractive Errors 审中-公开
$System and Method for Correction of Ophthalmic Refractive Errors$
标题翻译：矫正眼科屈光不正的系统和方法
公开(公告)号：US20130317488A1
公开(公告)日：2013-11-28
申请号：US13953311
申请日：2013-07-29
申请人： Friedrich Moritz , Gerhard Youssefi
发明人： Friedrich Moritz , Gerhard Youssefi
IPC分类号： A61F9/008
CPC分类号： A61F9/008 , A61F9/007 , A61F9/00806
摘要： The present invention relates to a system and a method for calculating a course of refractive treatment for correcting a refractive error of a patient's eye. It is based on the concept to combine at least a first treatment which provides an overcorrection of the intended correction with at least a second treatment which corrects said overcorrection.
摘要翻译：本发明涉及一种用于计算用于矫正患者眼睛屈光不正的折射治疗过程的系统和方法。这是基于将至少第一种处理结合起来的概念，该第一种处理提供预期校正的过度校正以及至少第二种处理，其校正所述过度校正。

8. 发明申请

US20120259320A1 System and Method for Performing Lens Fragmentation 审中-公开
标题翻译：执行镜头碎片的系统和方法
公开(公告)号：US20120259320A1
公开(公告)日：2012-10-11
申请号：US13436352
申请日：2012-03-30
申请人： Frieder Loesel , Jochen Kandulla , Friedrich Moritz , Gwillem Mosedale , Holger Schlueter , Roland Toennies , Gerhard Youssefi , David Haydn Mordaunt
发明人： Frieder Loesel , Jochen Kandulla , Friedrich Moritz , Gwillem Mosedale , Holger Schlueter , Roland Toennies , Gerhard Youssefi , David Haydn Mordaunt
IPC分类号： A61B18/20
CPC分类号： A61F9/00825 , A61F2009/00851 , A61F2009/0087 , A61F2009/00887
摘要： A system and method are provided for fragmenting a crystalline lens, to facilitate its removal from the lens bag during an ophthalmic laser surgery. First, a predetermined pattern is used to make Laser Induced Optical Breakdown (LIOB) cuts that section the lens into asymmetrical, operational segments. At least one operational segment is then selected and softened with a plurality of compact LIOB cuts. Once softened, the selected segment is aspirated. The remaining operational segments are then subsequently removed. During a procedure, an imaging unit can monitor movements of the lens bag to ensure proper placement of the LIOB cuts on the lens.
摘要翻译：提供了一种用于使晶状体碎裂的系统和方法，以便于在眼科激光手术期间从晶状体袋移除晶状体。首先，使用预定的图案来制造将透镜划分为不对称的，可操作的部分的激光诱导光学分解（LIOB）切割。然后，利用多个紧凑的LIOB切割来选择和软化至少一个操作段。一旦软化，所选择的部分被吸出。其余的操作段随后被移除。在一个过程中，成像单元可以监控透镜袋的运动，以确保LIOB切口在透镜上的正确放置。

9. 发明申请

US20050110946A1 Objective manifest refraction 有权
$Objective manifest refraction$
标题翻译：客观明显折射
公开(公告)号：US20050110946A1
公开(公告)日：2005-05-26
申请号：US10972096
申请日：2004-10-22
申请人： Gerhard Youssefi , Friedrich Moritz
发明人： Gerhard Youssefi , Friedrich Moritz
IPC分类号： A61B3/10 , A61B3/103 , A61B3/00
CPC分类号： A61B3/0025 , G06F19/00
摘要： An method for providing an objective manifest refraction of a patient's eye includes obtaining at least fourth-order Zernike wavefront aberration information, fitting a second-order only polynomial to the at least fourth-order data, and using this information to predict the patient's manifest refraction with an accuracy approaching the patient's subjective manifest refraction. A method is also described for prescribing an accurate vision correction based upon the objective manifest refraction. A display according to the invention includes higher-order wavefront aberrations, lower order wavefront aberrations, numerical indicia of predicted manifest refraction, and images of qualitative assessments of a patient's vision quality. A device for obtaining an objective manifest refraction is described.
摘要翻译：用于提供患者眼睛的客观清晰度折射的方法包括获得至少四阶Zernike波前像差信息，将二阶唯一多项式拟合到至少四阶数据，并且使用该信息来预测患者的明显折射准确地接近患者的主观显示折射。还描述了一种基于客观清晰度折射来规定准确的视力矫正的方法。根据本发明的显示器包括更高阶波前像差，较低阶波阵面像差，预测明显折射的数字标记以及患者视力质量的定性评估图像。描述了用于获得客观清晰度折射的装置。

10. 发明申请

US20110276043A1 Apparatus and method for providing a laser shot file 有权
标题翻译：用于提供激光拍摄文件的装置和方法
公开(公告)号：US20110276043A1
公开(公告)日：2011-11-10
申请号：US13098267
申请日：2011-04-29
申请人： Gerhard Youssefi , Ernst Hegels
发明人： Gerhard Youssefi , Ernst Hegels
IPC分类号： A61F9/008
CPC分类号： A61F9/008 , A61F9/00806 , A61F2009/00848 , A61F2009/00857 , A61F2009/00872 , A61F2009/0088 , A61F2009/00882
摘要： The invention relates to an apparatus, an algorithm and a method for providing a laser shot file for use in a laser. The laser may be an excimer laser. The shot file may be applied for performing a refractive laser treatment of an eye or for producing a customized contact lens or an intraocular lens. According to the invention information with respect to a desired ablation profile is provided and a first series of laser shot positions is calculated based on the desired ablation profile. A simulated ablation profile is generated using said first series of laser shot positions and using information about pulse characteristics of a single laser shot. The simulated ablation profile is compared with the desired ablation profile and residual structures are determined.
摘要翻译：本发明涉及一种用于提供用于激光器的激光射击文件的装置，算法和方法。激光可以是准分子激光器。射击文件可以用于执行眼睛的折射激光治疗或用于制造定制的隐形眼镜或眼内透镜。根据本发明，提供关于期望的消融轮廓的信息，并且基于期望的消融轮廓来计算第一系列的激光拍摄位置。使用所述第一系列激光拍摄位置并使用关于单个激光射击的脉冲特性的信息来生成模拟消融轮廓。将模拟的消融轮廓与期望的消融轮廓进行比较，并确定残余结构。

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