专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US5550232A Diastereomers of 1-(isopropoxycarbonyloxy) ethyl 3-cephem 4-carboxylate 失效
标题翻译： 1-（异丙氧基羰基氧基）乙基3-头孢烯-4-羧酸酯的非对映异构体
公开(公告)号：US5550232A
公开(公告)日：1996-08-27
申请号：US447229
申请日：1995-05-22
申请人： Gerd Fischer , Elisabeth Defossa , Uwe Gerlach , Rolf H orlein , Norbert Krass , Rudolf Lattrell , Ulrich Stache , Theodor Wollmann , Dieter Isert
发明人： Gerd Fischer , Elisabeth Defossa , Uwe Gerlach , Rolf H orlein , Norbert Krass , Rudolf Lattrell , Ulrich Stache , Theodor Wollmann , Dieter Isert
IPC分类号： A61K31/545 , A61K31/546 , A61P31/04 , C07D501/00 , C07D501/06 , C07D501/34 , C07D501/56 , C07D501/14
CPC分类号： C07D501/00
摘要： Enterally absorbable diastereomers of 1-(isopropoxycarbonyloxy)ethyl (6R,7R)-7-[2-(2-aminothiazol-4-yl)-2-(Z)-(methoxyimino)acetamido]-3-(methoxymethyl)-3-cephem-4-carboxylate of the formula I ##STR1## and their physiologically acceptable salts and also diastereomerically pure salts of the compounds of the formula II ##STR2## where HX is a mono- or polybasic acid and where X is an inorganic or organic physiologically acceptable anion, and a process for the preparation of these compounds of the formula I or II, which comprises first precipitating the more sparingly soluble diastereomer of the formula IV in the mixing together of 1 equivalent of a solution of the diastereomer mixture of the formula III with 0.2-2 equivalents of a solution of the acid component HY and separating it off by filtration, then precipitating the more readily soluble diastereomer of the formula IV from the filtration solution, it being possible for the acid component HY to be identical or different in the consecutive partial steps and any desired sequence of addition of different acid components HY being possible, and optionally further purifying the obtained salts by crystallization, are described.
摘要翻译： 1-（异丙氧羰基氧基）乙基（6R，7R）-7- [2-（2-氨基噻唑-4-基）-2-（Z） - （甲氧基亚氨基）乙酰氨基] -3-（甲氧基甲基）-3 式I的化合物 - 头孢烯-4-羧酸酯及其生理学上可接受的盐以及式II化合物的非对映体纯盐，其中HX是单或多元酸，其中X是无机或有机的生理学上可接受的阴离子，以及制备这些式I或II化合物的方法，其包括首先将式IV的较微溶的非对映体沉淀在1当量的式（I）的非对映体混合物的溶液中， III与0.2-2当量的酸组分HY的溶液并通过过滤分离，然后从过滤溶液中沉淀出更容易溶解的式IV的非对映异构体，酸组分HY可能相同或不同在一起描述了部分步骤和任何期望的不同酸组分HY的加入顺序是可能的，并且任选地通过结晶进一步纯化得到的盐。

2. 发明授权

US5188865A Production of a magnetic recording medium 失效
标题翻译：制作磁记录介质
公开(公告)号：US5188865A
公开(公告)日：1993-02-23
申请号：US866587
申请日：1992-04-10
申请人： Hans J. Richter , Hartmut Hibst , Gerd Fischer
发明人： Hans J. Richter , Hartmut Hibst , Gerd Fischer
IPC分类号： C23C14/24 , G11B5/85
CPC分类号： G11B5/85
摘要： A magnetic recording medium, consisting essentially of a polymeric, web-like substrate and a coherent thin layer of a ferromagnetic material, is produced in a chamber under reduced pressure by depositing a vapor jet of the ferromagnetic material onto the moving substrate surface guided over a cylindrical drum, by a process in which the axis of the cooling element is inclined relative to the plane of the evaporator unit.
摘要翻译：基本上由聚合物网状衬底和铁磁性材料的相干薄层组成的磁记录介质通过将铁磁材料的蒸汽射流沉积在导向的移动衬底表面上而在减压下在腔室中产生通过冷却元件的轴线相对于蒸发器单元的平面倾斜的过程，圆筒形滚筒。

3. 发明授权

US5417896A Preparation of sheet-like polyethylene terephthalate materials having little surface roughness 失效
标题翻译：制备表面粗糙度小的片状聚对苯二甲酸乙二醇酯材料
公开(公告)号：US5417896A
公开(公告)日：1995-05-23
申请号：US99139
申请日：1993-07-29
申请人： Gerd Fischer , Alfred Hagemeyer , Hartmut Hibst , Hans J. Richter , Hans-Peter Schildberg , Sylvain Lazare , Matthias Bolle
发明人： Gerd Fischer , Alfred Hagemeyer , Hartmut Hibst , Hans J. Richter , Hans-Peter Schildberg , Sylvain Lazare , Matthias Bolle
IPC分类号： C08J7/00 , B23K26/00 , B29C35/08 , B29C59/16 , C08G63/88 , C08J5/18 , G11B5/73 , G11B5/84 , H05K3/38 , C08J3/28
CPC分类号： G11B5/7315 , B29C59/16 , C08G63/88 , C08J5/18 , G11B5/8404 , B29C2035/0827 , B29C2035/0838 , B29C2791/001 , B29K2067/06 , C08J2367/02 , H05K3/381
摘要： Sheet-like PET materials having slight surface roughness consisting of fine dot patterns in the submicron range are produced by double successive exposure of the surfaces to polarized UV light produced by a pulsed excimer laser and having planes of polarization arranged at an angle of from 20.degree. to 90.degree. relative to one another, and the PET films treated in this manner are used as a substrate for thin ferromagnetic metal layers.
摘要翻译：具有由亚微米范围内的微小点图案组成的轻微表面粗糙度的片状PET材料通过将表面双重曝光到由脉冲准分子激光器产生的偏振UV光并具有以20°的角度排列的偏振面相对于彼此为90度，并且以这种方式处理的PET膜用作薄铁磁性金属层的基板。

4. 发明授权

US5410042A Process for the cleavage of cephalosporin prodrug esters to 7-amino-3-methoxymethylceph-3-em-4-carboxylic acid 失效
标题翻译：将头孢菌素前药酯切割成7-氨基-3-甲氧基甲基头孢-3-烯-4-羧酸的方法
公开(公告)号：US5410042A
公开(公告)日：1995-04-25
申请号：US063574
申请日：1993-05-19
申请人： Norbert Krass , Elisabeth Defossa , Gerd Fischer , Uwe Gerlach , Rolf Hoerlein , Rudolf Lattrell , Adolf H. Linkies , Wolfgang Martin , Ulrich Stache , Theodor Wollmann
发明人： Norbert Krass , Elisabeth Defossa , Gerd Fischer , Uwe Gerlach , Rolf Hoerlein , Rudolf Lattrell , Adolf H. Linkies , Wolfgang Martin , Ulrich Stache , Theodor Wollmann
IPC分类号： C07D501/00 , C07D501/04 , C07D501/18
CPC分类号： C07D501/00
摘要： The present invention relates to a process for the preparation of 7-amino-3-methoxymethylceph-3-em-4-carboxylic acid (I) from 7-amino-3-methoxymethylceph-3-em-4-carboxylic acid esters (II) or their salts by ester cleavage.The process comprises treating the compound II with formic acid, trifluoroacetic acid, methanesulfonic acid or trifluoromethanesulfonic acid or a mixture of two of these acids in each case.
摘要翻译：本发明涉及从7-氨基-3-甲氧基甲基头孢-3-烯-4-羧酸酯（II）制备7-氨基-3-甲氧基甲基头孢-3-烯-4-羧酸（I）的方法）或它们的盐通过酯裂解。该方法包括在各种情况下用甲酸，三氟乙酸，甲磺酸或三氟甲磺酸或这些酸的两种混合物处理化合物II。

5. 发明授权

US5306717A Cephalosporin derivatives 失效
标题翻译：头孢菌素衍生物
公开(公告)号：US5306717A
公开(公告)日：1994-04-26
申请号：US924598
申请日：1992-07-24
申请人： Friedhelm Adam , Walter Durckheimer , Gerd Fischer , Burkhard Mencke , Gerhard Seibert , Dieter Isert , Norbert Klesel
发明人： Friedhelm Adam , Walter Durckheimer , Gerd Fischer , Burkhard Mencke , Gerhard Seibert , Dieter Isert , Norbert Klesel
IPC分类号： A61K20060101 , A61K31/545 , A61K31/546 , A61P31/04 , C07D20060101 , C07D501/00 , C07D501/04 , C07D501/06 , C07D501/22 , C07D501/34 , C07D501/46
CPC分类号： C07D501/34
摘要： Cephalosporin derivatives of the general formula ##STR1## pharmaceutical preparations which are active against bacterial infections and contain such cephem derivatives, processes for the preparation of the cephem derivatives and the pharmaceutical preparations and the use of the cephem derivatives for combating bacterial infections.
摘要翻译：具有抗细菌感染和含有此类头孢烯衍生物的通式为“IMAGE”+ TR 的药物制剂的头孢菌素衍生物，头孢烯衍生物和药物制剂的制备方法以及头孢烯衍生物用于对抗细菌感染。

6. 发明授权

US5290590A Production of magnetic recording medium 失效
标题翻译：生产磁记录介质
公开(公告)号：US5290590A
公开(公告)日：1994-03-01
申请号：US822259
申请日：1992-01-17
申请人： Hans J. Richter , Hartmut Hibst , Gerd Fischer
发明人： Hans J. Richter , Hartmut Hibst , Gerd Fischer
IPC分类号： C23C14/24 , G11B5/85 , B05D5/12
CPC分类号： G11B5/85
摘要： A magnetic recording medium, consisting essentially of a polymeric, web-like substrate and a coherent thin layer of a ferromagnetic material is produced in a reduced-pressure chamber by depositing a vapor jet of the ferromagnetic material onto the moving substrate surface which is fed on a cylindrical drum.
摘要翻译：在减压室中通过将铁磁材料的蒸汽射流沉积到移动的衬底表面上来制造基本上由聚合物网状衬底和铁磁材料的粘结薄层组成的磁记录介质，圆柱形鼓。

7. 发明申请

US20120175622A1 METHOD FOR PRODUCING A SILICON INGOT 有权
标题翻译：生产硅胶的方法
公开(公告)号：US20120175622A1
公开(公告)日：2012-07-12
申请号：US13339488
申请日：2011-12-29
申请人： Andreas Krause , Bernhard Freudenberg , Gerd Fischer , Josef Stenzenberger , Mark Hollatz , Armin Müller
发明人： Andreas Krause , Bernhard Freudenberg , Gerd Fischer , Josef Stenzenberger , Mark Hollatz , Armin Müller
IPC分类号： H01L29/04 , C01B33/021 , C01B33/02
CPC分类号： C30B29/06 , C30B11/003 , C30B11/14
摘要： Method for producing a silicon ingot, comprising the following steps: providing a container to receive a silicon melt, providing a temperature control device to control the temperature of the silicon melt in the container, arranging raw material in the container comprising silicon and at least one nucleation agent to assist a heterogeneous nucleation in the silicon melt, and control of the temperature in the container for the directed solidification of the silicon melt , the nucleation agent comprising nanoscale particles.
摘要翻译：制造硅锭的方法，包括以下步骤：提供容器以接收硅熔体，提供温度控制装置以控制容器中硅熔体的温度，将原料排列在包含硅和至少一个成核剂以帮助硅熔体中的异相成核，以及控制容器中的温度以使硅熔体的定向固化，成核剂包含纳米级颗粒。

8. 发明授权

US06837543B2 Seat, for automobiles or the like 失效
标题翻译：座椅，汽车等
公开(公告)号：US06837543B2
公开(公告)日：2005-01-04
申请号：US10198123
申请日：2002-07-19
申请人： Roland Och , Gerd Fischer
发明人： Roland Och , Gerd Fischer
IPC分类号： A47C3/025 , A47C7/46 , B60N2/66
CPC分类号： B60N2/6671 , B60N2/666
摘要： A seat for an automobile includes a backrest fitted with a frame, an adjusting device inside the backrest in the region of the lumbar vertebral column, an elongated, resiliently bending element running transversely inside the frame, two bowden cables each with a sheath and a traction wire, a drive device at the backrest one rest for each bowden cable sheath in each end zone off the elongated element and through which the traction wire is made to pass in longitudinally displaceable manner, an affixation of the free end of the traction wire at a part of the backrest frame facing it whereby the elongated element is suspended in such manner in the frame that, when a tension is exerted on the traction wire, the elongated element shall be moved forward.

9. 发明授权

US5589594A Process for the preparation of cephem prodrug esters 失效
标题翻译：头孢烯前药酯的制备方法
公开(公告)号：US5589594A
公开(公告)日：1996-12-31
申请号：US176501
申请日：1993-12-30
申请人： Elisabeth Defossa , Gerd Fischer , Uwe Gerlach , Rolf Horlein , Norbert Krass , Rudolf Lattrell , Ulrich Stache , Theodor Wollmann
发明人： Elisabeth Defossa , Gerd Fischer , Uwe Gerlach , Rolf Horlein , Norbert Krass , Rudolf Lattrell , Ulrich Stache , Theodor Wollmann
IPC分类号： A61K31/545 , A61K31/546 , A61P31/04 , C07D277/20 , C07D277/40 , C07D417/12 , C07D501/00 , C07D501/04 , C07D501/06 , C07D501/34 , C07D501/02
CPC分类号： C07D277/587 , C07D417/12 , C07D501/00 , Y02P20/55
摘要： The invention relates to a process for the preparation of cephem prodrug esters of the formula: ##STR1## in which R.sup.1 is C.sub.1 -C.sub.5 -alkanoyloxy-C.sub.1 -C.sub.3 -alkyl or C.sub.1 -C.sub.5 -alkoxycarbonyloxy-C.sub.1 -C.sub.3 -alkyl and X is an inorganic or organic anion, and in which the hydroxyimino group is present in the syn-form.
摘要翻译：本发明涉及一种制备下式的头孢烯前药酯的方法：其中R 1是C 1 -C 5 - 烷酰氧基-C 1 -C 3 - 烷基或C 1 -C 5 - 烷氧羰基氧基-C 1 -C 3烷基和X 是无机或有机阴离子，其中羟基亚氨基以合成形式存在。

10. 发明授权

US5556850A Crystalline acid addition salts of diastereomerically pure 1-(2,2-dimethyl-propionyloxy)-ethyl-3-cephem-4-carboxylate 失效
标题翻译：非对映体纯的1-（2,2-二甲基 - 丙酰氧基） - 乙基-3-头孢烯-4-羧酸的结晶酸加成盐
公开(公告)号：US5556850A
公开(公告)日：1996-09-17
申请号：US447635
申请日：1995-05-23
申请人： Elisabeth Defossa , Gerd Fischer , Joachim-Heiner Jendralla , Rudolf Lattrell , Theodor Wollmann , Dieter Isert
发明人： Elisabeth Defossa , Gerd Fischer , Joachim-Heiner Jendralla , Rudolf Lattrell , Theodor Wollmann , Dieter Isert
IPC分类号： A61K31/545 , A61K31/546 , A61P31/04 , C07B57/00 , C07D417/12 , C07D501/00 , C07D501/12 , C07D501/18 , C07D501/32 , C07D501/34
CPC分类号： C07D501/00
摘要： The invention relates to crystalline acid addition salt of the two diastereomers of the 1-(2,2-dimethylpropionyloxy)ethyl 3-cephem-4-carboxylate of the general formula II ##STR1## in which X is the anion of a physiologically acceptable, mono- or polybasic, inorganic or organic acid and the group .dbd.N--OH is in the syn-position, pharmaceutical formulations which are active against bacterial infections and contain such cephem derivatives, processes for the preparation of the cephem derivatives and the use of the cephem derivatives for combating bacterial infections.
摘要翻译：本发明涉及通式II II的1-（2,2-二甲基丙酰氧基）乙基3-头孢烯-4-羧酸酯的两种非对映异构体的结晶酸加成盐，其中X是生理上可接受的单 - 或多碱性，无机或有机酸，并且组= N-OH处于顺式位置，对细菌感染有活性并含有此类头孢烯衍生物的药物制剂，用于制备头孢烯衍生物的方法和使用用于对抗细菌感染的头孢烯衍生物。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式