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    • 5. 发明授权
    • Endolumenal stent-graft with leak-resistant seal
    • 腔内支架移植物具有防漏密封
    • US6015431A
    • 2000-01-18
    • US773479
    • 1996-12-23
    • Troy ThorntonLilip Lau
    • Troy ThorntonLilip Lau
    • A61F2/00A61F2/06
    • A61F2/07A61F2/97A61F2/848A61F2/89A61F2/954A61F2002/067A61F2002/075A61F2002/9511A61F2220/0075A61F2230/0054A61F2230/0078A61F2250/0039
    • An implantable medical device has a tubular member and a sealing member secured to an outer surface of the tubular member. The tubular member is expandable to engage an endolumenal wall and has a lumen for providing an artificial conduit for flow through an endolumenal space defined by that wall. The seal member occludes flow around the tubular member between the outer surface and the endolumenal wall. One suitable tubular member for use in the present invention is a stent-graft which may be bifurcated for use in protecting vascular wall malformations adjacent to vascular bifurcations against endolumenal pressure and flow. The seal member may be a flange that is oriented on the outer surface at one end of the tubular member as a one-way valve against flow. Multiple seal members may be used, either on opposite ends of the tubular member or in series at one end thereof. Where anchors are used to secure the tubular member to the endolumenal wall, the seal member is positioned to protect against flow through leakage paths formed at localized areas of deformation in the tubular wall adjacent to the anchors. One or more seal members may also be used with two or more tubular members to prevent flow through endolumenal spaces that remain open to flow due to gaps between the multiple, parallel tubular members.
    • 可植入医疗装置具有管状构件和固定到管状构件的外表面的密封构件。 管状构件可扩张以接合内腔壁,并具有内腔,用于提供用于流过由该壁限定的腔室空间的人造管道。 密封构件在外表面和内腔壁之间封闭管状构件周围的流动。 用于本发明的一种合适的管状构件是支架移植物,其可以分叉用于保护邻近血管分叉的血管壁畸形以抵抗内腔内压力和流动。 密封构件可以是在管状构件的一端的外表面上定向为防止流动的单向阀的凸缘。 可以在管状构件的相对端上或在其一端串联使用多个密封构件。 在使用锚固件将管状构件固定到内腔壁的情况下,密封构件被定位成防止流过形成在与锚固件相邻的管状壁中的局部变形区域处的泄漏路径。 一个或多个密封构件也可以与两个或多个管状构件一起使用,以防止由于多个平行的管状构件之间的间隙而保持开放的内腔空间的流动。