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1. 发明申请

US20090017865A1 MAKING CALLS USING THE PREFERRED NETWORK 审中-公开
标题翻译：使用优选网络进行呼叫
公开(公告)号：US20090017865A1
公开(公告)日：2009-01-15
申请号：US11777612
申请日：2007-07-13
申请人： Gary Cole , Charles Liu , Dan Ding
发明人： Gary Cole , Charles Liu , Dan Ding
IPC分类号： H04M1/00
CPC分类号： H04W8/18 , H04M1/2745 , H04M1/274508 , H04M1/677 , H04M1/72563 , H04M2250/06 , H04W48/18
摘要： A portable electronic device includes call circuitry operable to establish a communication link over a plurality of different communication networks, and a logic circuit operatively coupled to said call circuitry. The logic circuit operative to automatically select a communication network of the plurality of different communication networks prior to establishing the communication link, said selection based on a predefined user preference.
摘要翻译：便携式电子设备包括可操作以在多个不同通信网络上建立通信链路的呼叫电路，以及可操作地耦合到所述呼叫电路的逻辑电路。逻辑电路可操作以在建立通信链路之前自动选择多个不同通信网络的通信网络，所述选择基于预定义的用户偏好。

2. 发明申请

US20140328764A1 Biocompatible Nanoparticles with Aggregation Induced Emission Characteristics as Fluorescent Bioprobes and Methods of Using the Same for In Vitro and In Vivo Imaging 审中-公开
标题翻译：具有聚集诱导的排放特性作为荧光生物探针的生物相容纳米颗粒及其在体外和体内成像中的使用方法
公开(公告)号：US20140328764A1
公开(公告)日：2014-11-06
申请号：US14342074
申请日：2012-09-03
申请人： Benzhong Tang , Wei Qin , Jianzhao Liu , Sijie Chen , Tsz Kin Kwok , Bin Liu , Kai Li , Dan Ding , Haibin Shi , Jun Long Geng , Jingzhi Sun , Anjun Qin , Qiuli Zhao
发明人： Benzhong Tang , Wei Qin , Jianzhao Liu , Sijie Chen , Tsz Kin Kwok , Bin Liu , Kai Li , Dan Ding , Haibin Shi , Jun Long Geng , Jingzhi Sun , Anjun Qin , Qiuli Zhao
IPC分类号： G01N33/58 , A61K49/00 , G01N33/574 , C12Q1/37
CPC分类号： G01N33/582 , A61K49/0021 , A61K49/0054 , A61K49/0093 , C09K11/06 , C12Q1/37 , G01N33/574 , G01N2333/96466
摘要： The development of fluorescent bioprobes comprising organic fluorescent compounds that exhibit aggregation induced emission (AIE) properties, methods of producing the same, and their practical applications for in vitro and in vivo bioimaging.
摘要翻译：荧光生物探针的发展包括显示聚集诱导发射（AIE）性质的有机荧光化合物，其生产方法及其在体外和体内生物成像中的实际应用。

3. 发明申请

US20130109029A1 Methods And Compositions For Cellular Imaging And Cancer Cell Detection Using Light Harvesting Conjugated Polymer-Biomolecular Conjugates 审中-公开
标题翻译：细胞成像的方法和组合和使用光收获共轭聚合物 - 生物分子结合体的癌细胞检测
公开(公告)号：US20130109029A1
公开(公告)日：2013-05-02
申请号：US13806447
申请日：2011-06-29
申请人： Bin Liu , Kanyi Pu , Kai Li , Liping Cai , Yanyan Wang , Dan Ding
发明人： Bin Liu , Kanyi Pu , Kai Li , Liping Cai , Yanyan Wang , Dan Ding
IPC分类号： C07K17/02
CPC分类号： C07K17/02 , B82Y15/00 , C07D285/10 , C09K11/06 , C09K2211/1416 , G01N33/582 , G01N33/588
摘要： The present invention relates to conjugated polyelectrolyte (CPE) or oligoelectrolyte (COE) compounds represented by general structural formulae (I)-(IV), or a salt thereof and methods of using these compounds to detect targets in samples. In particular, the methods include: (1) exposing a sample to a compound of structural formula (I), (II) or (IV) or a salt thereof, allowing the compound to bind to a target and detecting a signal produced by the compound; (2) functionalizing a solid support with a ligand, incubating the sample with a charged CPE or COE and detecting the fluorescence of the solid support and thereby detecting the target or (3) functionalizing a surface of a solid support with a charged ligand, thereby creating a charge on the surface of the solid support; incubating the ligand-functionalized solid support with a sample, whereupon binding of the target, the charge on the surface of the solid support switches; incubating the sample with CPE or COE that has a complementary charge to the charge of the target-bound surface; and detecting the fluorescence of the solid support and thereby detecting the target. The compounds of the present invention possess high photoluminescence quantum yields in biological media, low cytotoxicity, and excellent environmental stability and photostability and can be used in biosensor and bioimaging applications.
摘要翻译：本发明涉及由通式（I） - （IV）表示的共轭聚电解质（CPE）或低聚电解质（COE）化合物或其盐，以及使用这些化合物检测样品中靶标的方法。特别地，所述方法包括：（1）将样品暴露于结构式（I），（II）或（IV）的化合物或其盐，使化合物与靶标结合并检测由复合; （2）用配体官能化固体支持物，将样品与带电荷的CPE或COE孵育并检测固体支持物的荧光，从而检测靶，或（3）用带电的配体使固体支持物的表面官能化，从而在固体支撑体的表面上产生电荷; 将配体官能化的固体支持物与样品一起孵育，随后靶标结合，固体支持开关表面上的电荷; 将样品与具有补充电荷的CPE或COE孵育到靶结合表面的电荷; 并检测固体支持物的荧光，从而检测目标物。本发明的化合物在生物培养基中具有高的光致发光量子产率，低的细胞毒性和优异的环境稳定性和光稳定性，并可用于生物传感器和生物成像应用。

4. 发明授权

US10753941B2 Biocompatible nanoparticles with aggregation induced emission characteristics as fluorescent bioprobes and methods of using the same for in vitro and in vivo imaging 有权
公开(公告)号：US10753941B2
公开(公告)日：2020-08-25
申请号：US14342074
申请日：2012-09-03
申请人： Benzhong Tang , Wei Qin , Jianzhao Liu , Sijie Chen , Tsz Kin Kwok , Bin Liu , Kai Li , Dan Ding , Haibin Shi , Jun Long Geng , Jingzhi Sun , Anjun Qin , Qiuli Zhao
发明人： Benzhong Tang , Wei Qin , Jianzhao Liu , Sijie Chen , Tsz Kin Kwok , Bin Liu , Kai Li , Dan Ding , Haibin Shi , Jun Long Geng , Jingzhi Sun , Anjun Qin , Qiuli Zhao
IPC分类号： A61B5/00 , A61B8/00 , A61B10/00 , G01N33/58 , A61K49/00 , C09K11/06 , C12Q1/37 , G01N33/574
摘要： The development of fluorescent bioprobes comprising organic fluorescent compounds that exhibit aggregation induced emission (AIE) properties, methods of producing the same, and their practical applications for in vitro and in vivo bioimaging.

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