专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US06951649B2 Methods of making neuraminidase-supplemented compositions 失效
标题翻译：制备补充神经氨酸酶的组合物的方法
公开(公告)号：US06951649B2
公开(公告)日：2005-10-04
申请号：US10264813
申请日：2002-10-04
申请人： Gail Eugene Smith , James T. Matthews , Edwin D Kilbourne , Bert E. Johansson , Bethanie E. Wilkinson , Andrie I. Voznesensky , Craig S. Hackett , Franklin Volvovitz
发明人： Gail Eugene Smith , James T. Matthews , Edwin D Kilbourne , Bert E. Johansson , Bethanie E. Wilkinson , Andrie I. Voznesensky , Craig S. Hackett , Franklin Volvovitz
IPC分类号： A61K39/00 , A61K39/12 , A61K39/145 , A61K39/39 , A61K48/00 , C07K14/11 , C12N15/33 , A61K39/295
CPC分类号： C07K14/005 , A61K39/00 , A61K39/12 , A61K39/145 , A61K39/39 , A61K48/00 , A61K2039/5252 , A61K2039/55516 , A61K2039/70 , C07K2319/00 , C07K2319/02 , C07K2319/035 , C07K2319/036 , C07K2319/40 , C07K2319/91 , C12N2710/14143 , C12N2760/16022 , C12N2760/16034 , C12N2760/16122 , C12N2760/16134 , C12N2760/16234
摘要： The present invention relates to a method for formulating a vaccine composition which comprises an anti-influenza vaccine, wherein the improvement of the vaccine composition is that the vaccine includes, as an additive, neuraminidase (NA). The base anti-influenza vaccine can be any commercially available anti-influenza vaccine. The improved composition can include and be administered with an adjuvant. The improved vaccine composition provides protection in a host, animal or human, against influenza infection, including viral replication and systemic infection.
摘要翻译：本发明涉及一种配制包含抗流感疫苗的疫苗组合物的方法，其中疫苗组合物的改进是疫苗包含作为添加剂的神经氨酸酶（NA）。基础抗流感疫苗可以是任何市售的抗流感疫苗。改进的组合物可以包含佐剂和与佐剂一起施用。改进的疫苗组合物在宿主，动物或人体中提供针对流感感染的保护，包括病毒复制和全身感染。

2. 发明授权

US06485729B1 Neuraminidase-supplemented compositions 失效
标题翻译：神经氨酸酶补充组合物
公开(公告)号：US06485729B1
公开(公告)日：2002-11-26
申请号：US09372734
申请日：1999-08-11
申请人： Gail Eugene Smith , James T. Matthews , Edwin D. Kilbourne , Bert E. Johansson , Bethanie E. Wilkinson , Andrei I. Voznesensky , Craig S. Hackett , Franklin Volvovitz
发明人： Gail Eugene Smith , James T. Matthews , Edwin D. Kilbourne , Bert E. Johansson , Bethanie E. Wilkinson , Andrei I. Voznesensky , Craig S. Hackett , Franklin Volvovitz
IPC分类号： A61K39145
CPC分类号： C07K14/005 , A61K39/00 , A61K39/12 , A61K39/145 , A61K39/39 , A61K48/00 , A61K2039/5252 , A61K2039/55516 , A61K2039/70 , C07K2319/00 , C07K2319/02 , C07K2319/035 , C07K2319/036 , C07K2319/40 , C07K2319/91 , C12N2710/14143 , C12N2760/16022 , C12N2760/16034 , C12N2760/16122 , C12N2760/16134 , C12N2760/16234
摘要： An anti-influenza vaccine composition wherein the improvement is that the vaccine includes, as an additive, neuraminidase (NA). The base anti-influenza vaccine can be any commercially available anti-influenza vaccine. The composition can include and be administered with an adjuvant. The vaccine composition provides protection in a host, animal or human, against influenza infection, including viral replication and systemic infection. Oral, nasal or other mucosal or per needle administration, including intracutaneous, intradermal, intramuscular, intravascular, and intravenous, are included.
摘要翻译：一种抗流感疫苗组合物，其中改进之处在于疫苗包含作为添加剂的神经氨酸酶（NA）。基础抗流感疫苗可以是任何市售的抗流感疫苗。该组合物可以包括并且与佐剂一起施用。疫苗组合物在宿主，动物或人体中提供针对流感感染的保护，包括病毒复制和全身感染。包括皮下，皮内，肌内，血管内和静脉内的口服，鼻或其他粘膜或每针给药。

3. 发明授权

US5016463A Apparatus and method for forming can bottoms 失效
标题翻译：用于形成罐底的装置和方法
公开(公告)号：US5016463A
公开(公告)日：1991-05-21
申请号：US548951
申请日：1990-09-04
申请人： Bert E. Johansson , Conrad M. Grims
发明人： Bert E. Johansson , Conrad M. Grims
IPC分类号： B21D22/30 , B21D51/26
CPC分类号： B21D22/30 , B21D51/26
摘要： A can bottom forming assembly for forming the bottom wall of a can body. A bodymaker punch urges a can bottom wall first against an outer forming ring, then against a middle forming ring, and then against a domer die.
摘要翻译： PCT No.PCT / US89 / 00337 Sec。 371 1990年9月4日第 102（e）1990年9月4日PCT PCT 1989年8月10日提交PCT。第WO89 / 07021号公报日期1989年8月10日。一种用于形成罐体底壁的底部成形组件。主体拳头首先将罐底壁抵靠外部成形环，然后抵靠中间成形环，然后抵靠一个三角形模具。

4. 发明授权

US5797292A Domer apparatus for a can body making apparatus 失效
标题翻译：用于罐体制造装置的Domer装置
公开(公告)号：US5797292A
公开(公告)日：1998-08-25
申请号：US640671
申请日：1996-05-01
申请人： Bert E. Johansson , Connie M. Grims, Sr.
发明人： Bert E. Johansson , Connie M. Grims, Sr.
IPC分类号： B21D22/30 , B21D22/00
CPC分类号： B21D22/30
摘要： Domer apparatus for forming desired surface contours on the closed end portion of a can body wherein an outer member is mounted for sliding movement in a direction parallel to the longitudinal axis of the domer apparatus and relative to an inner member and wherein the outer member and the inner member are mounted for movement in radial directions in response to forces applied thereto by the closed end portion of the can body to center the outer member and the inner member relative to the closed end portion of the can body.
摘要翻译：一种用于在罐体的封闭端部上形成所需表面轮廓的多孔装置，其中外部构件安装成用于在平行于所述圆顶装置的纵向轴线的方向上相对于内部构件滑动运动，并且其中所述外部构件和内部构件被安装成响应于由罐体的封闭端部施加到其上的力沿径向方向运动，以使外部构件和内部构件相对于罐体的封闭端部中心。

5. 发明授权

US5056350A Apparatus and method for stripping a workpiece from a supporting device 失效
标题翻译：用于从支撑装置剥离工件的装置和方法
公开(公告)号：US5056350A
公开(公告)日：1991-10-15
申请号：US562747
申请日：1990-08-06
申请人： Bruce A. Moen , Warren R. Williams , Bert E. Johansson , Leo W. Mayer
发明人： Bruce A. Moen , Warren R. Williams , Bert E. Johansson , Leo W. Mayer
IPC分类号： B21D22/30 , B21D45/08 , B21D51/26
CPC分类号： B21D22/30 , B21D45/08 , B21D51/26
摘要： Apparatus and method for stripping a can body having an open end and a closed end from the punch on a reciprocating ram of a can body making apparatus wherein a cavity exists between the closed end and the punch and wherein the ram has a forward stroke and a return stroke by moving the closed end into contact with doming apparatus during the forward stroke to move a valve from a closed to an opened position to feed air under pressure into the cavity to hold the closed end against the doming apparatus during the return stroke until the can body is separated from the punch and ejecting the stripped can body from the doming apparatus.
摘要翻译：用于在罐体制造装置的往复运动的冲头上从冲头剥离具有开口端和封闭端的罐体的装置和方法，其中在封闭端和冲头之间存在空腔，并且其中冲头具有前冲程和通过在向前冲程期间将封闭端移动到与隆起装置接触的返回行程，以将阀从关闭位置移动到打开位置，以将压力下的空气供给到空腔中，以在返回冲程期间将封闭端保持抵靠拱顶装置直到罐体与冲头分离，并从圆顶装置喷出剥离的罐体。

6. 发明授权

US5054341A Apparatus and method for trimming a can body 失效
标题翻译：用于修剪罐体的装置和方法
公开(公告)号：US5054341A
公开(公告)日：1991-10-08
申请号：US435196
申请日：1989-11-13
申请人： Bert E. Johansson , Ray L. Bowles
发明人： Bert E. Johansson , Ray L. Bowles
IPC分类号： B23D31/00
CPC分类号： B23D31/001 , Y10T82/16016 , Y10T82/16032 , Y10T82/16114 , Y10T82/16181 , Y10T82/16213
摘要： Apparatus and method for trimming away a portion of the open end of an untrimmed can body to form a trimmed can body and a trimmed away portion using a plurality of can trimming apparatuses which are mounted on a turret which is secured to a main drive shaft for rotation therewith. Each of the can trimming apparatus has mechanisms for cutting the untrimmed can body to form a trimmed can body and a trimmed away portion; for separating the trimmed can body from the trimmed away portion by moving both in one axial direction and then only the trimmed can body in the opposite axial direction; for loading untrimmed can bodies onto each can processing apparatus and for unloading trimmed can bodies therefrom and for cutting, knurling and disposing of the trimmed away portions. A collapsibe mandrel is provided and comprises a hollow support member having a plurality of axially and radially outwardly extending resilient fingers integral therewith and a bearing surface mounted on an adjustable elongated hollow member in contact with the resilient fingers to control the radially outward extent thereof. Also, an annular spacer is located between a first knife and a first knurling roller to provide a space for the portion to be trimmed away prior to the knurling operation. A positive can body loading and unloading system is also provided.
摘要翻译：用于修剪未修剪的罐体的开口端的一部分的装置和方法，以使用多个可修剪装置形成修剪后的罐体和修剪部分，所述多个可修剪装置安装在转动架上，该转台固定到主驱动轴上与其旋转。每个可修剪装置具有用于切割未修剪的罐体以形成修剪的罐体和修剪掉的部分的机构; 用于通过在一个轴向方向上移动，然后仅在相对的轴向方向上仅修剪的罐体来将修剪后的罐体与修剪后的部分分离; 用于将未修整的罐体装载到每个罐加工装置上并用于从其中卸载修剪的罐体，以及用于切割，滚花和处理已修剪的部分。提供了折叠式心轴，并且包括具有与其成一体的多个轴向和径向向外延伸的弹性指状件的中空支撑构件和安装在与弹性指接触的可调节细长中空构件上以控制其径向向外范围的支承表面。此外，环形间隔件位于第一刀和第一滚花辊之间，以在滚花操作之前为要修剪的部分提供空间。还提供了正罐体装卸系统。

7. 发明授权

US4969635A Apparatus for use in trimming can bodies 失效
标题翻译：用于修剪罐体的装置
公开(公告)号：US4969635A
公开(公告)日：1990-11-13
申请号：US337359
申请日：1989-04-13
申请人： Bert E. Johansson , Ray L. Bowles , Leroy J. Haverland
发明人： Bert E. Johansson , Ray L. Bowles , Leroy J. Haverland
IPC分类号： B23D31/00
CPC分类号： B23D31/001
摘要： A collapsible mandrel for use in holding a can body in a process wherein a portion of the can body having uneven edges on the open end thereof is trimmed away is provided and comprises a hollow support member having a longitudinal axis and mounted at a relatively fixed location and having a plurality of axially and radially outwardly extending resilient fingers integral therewith and an elongated hollow member mounted on the hollow support member to provide for linear movement therebetween. The elongated hollow member has a bearing surface in contact with the resilient fingers so that movement of the elongated hollow member varies the radially outwardly extent of the resilient fingers so that can bodies having inner peripheral surfaces of differing inner diameters may be readily moved over the resilient fingers but wherein the resilient fingers will exert a sufficient force thereon so that the can body will rotate with the resilient fingers. A movement limiting member is mounted within the resilient fingers so as to limit the radially inward movement of the resilient fingers. A locking device is provided to prevent the rotation of the elongated hollow member.
摘要翻译：一种用于保持罐体的可折叠芯棒，其中在其开口端具有不平坦边缘的罐体的一部分被修剪掉，并且包括具有纵向轴线并安装在相对固定位置的中空支撑构件并且具有与其成一体的多个轴向和径向向外延伸的弹性指状物，以及安装在中空支撑构件上以提供它们之间线性运动的细长型中空构件。细长的中空构件具有与弹性指状物接触的支承表面，使得细长的中空构件的运动改变弹性指状物的径向向外的范围，使得具有不同内径的内周表面的罐体可以容易地移动到弹性手指，但是其中弹性指状物将在其上施加足够的力，使得罐体将随着弹性指状物旋转。移动限制构件安装在弹性指状件内，以限制弹性指的径向向内移动。提供锁定装置以防止细长的中空构件的旋转。

8. 发明授权

US4934167A Can body making apparatus 失效
标题翻译：罐身制作机
公开(公告)号：US4934167A
公开(公告)日：1990-06-19
申请号：US392446
申请日：1989-08-11
申请人： Conrad M. Grims , Bert E. Johansson , Roger A. Hahn
发明人： Conrad M. Grims , Bert E. Johansson , Roger A. Hahn
IPC分类号： B21D22/30 , B21D51/26
CPC分类号： B21D22/30 , B21D51/26
摘要： A redraw apparatus is provided for a can body making apparatus wherein the redraw carriage of the redraw apparatus is mounted for substantially friction-free sliding reciprocating movement over a pair of spaced apart support posts which are fixed mounted on the housing holding the can forming and ironing dies. Also, the counterbalancing system is provided for applying a force to counterbalance the weight of a portion of structures used to reciprocate the redraw carriage. Additionally, a ram assembly is provided for supporting a ram for movement through the redraw apparatus and the can forming and ironing dies wherein a pair of spaced apart elongated shafts are fixedly mounted and a ram carriage having the ram attached thereto is provided with liquid bearings using liquid coolant comprising water having solubles contained therein for mounting the ram carriage on the elongated shafts for substantially friction free movement thereover. A guide liquid bearing is also used to ensure proper alignment of the ram. Also disclosed is a reciprocating ram which is supported solely by a liquid bearing wherein the liquid bearing using liquid coolant comprising water having solubles contained therein has a sufficient length to ensure the proper alignment of the leading portion of the elongated ram as it engages a can blank in a redraw assembly and moves it through the forming and ironing dies to form an elongated can body.
摘要翻译：为罐体制造装置提供了一种再绘画装置，其中重画装置的重新拉出装置安装成用于在一对间隔开的支撑柱上实质上无摩擦的滑动往复运动，固定安装在保持罐形成和熨烫的壳体上死了此外，平衡系统被提供用于施加力以平衡用于使重新拉出托架往复运动的结构的一部分的重量。另外，提供了一种活塞组件，用于支撑用于移动的冲头，用于移动通过重新拉出装置和罐形成和熨烫模具，其中一对间隔开的细长轴被固定地安装，并且具有附接到其上的柱塞的冲头滑架设置有使用液体冷却剂包括其中容纳有可溶物的水，用于将柱塞滑架安装在细长轴上，用于在其上基本上无摩擦力的运动。引导液体轴承也用于确保冲头的正确对准。还公开了一种往复运动的冲头，其仅由液体轴承支撑，其中使用包含其中容纳可溶物的水的液体冷却剂的液体轴承具有足够的长度，以确保细长冲头的引导部分与罐坯体接合时的适当对准在重画组件中并将其移动通过成型和熨烫模具以形成细长的罐体。

9. 发明授权

US5404776A Apparatus for trimming a can body 失效
标题翻译：用于修剪罐体的装置
公开(公告)号：US5404776A
公开(公告)日：1995-04-11
申请号：US52363
申请日：1993-04-23
申请人： Bert E. Johansson , Ray L. Bowles
发明人： Bert E. Johansson , Ray L. Bowles
IPC分类号： B23D21/00 , B23D31/00 , B23B1/00
CPC分类号： B23D31/001 , B23D21/00 , Y10T82/16016 , Y10T82/16114 , Y10T82/16181 , Y10T82/16213
摘要： Apparatus for trimming away the open end of an untrimmed can body using a plurality of can trimming apparatuses mounted on a rotating turret wherein each can trimming apparatus has a rotatable first shaft having a radially outer or inner knife and a knurling roller mounted thereon for rotation therewith and a second rotatable shaft having a radially inner or outer knife and a knurling segment mounted thereon for rotation therewith and wherein, for each complete revolution of the turret, the first shaft makes three complete revolutions and the second shaft makes one complete revolution. Also, an arrangement of gears is provided for rotating the firs and second shafts.
摘要翻译：用于使用安装在旋转转台上的多个可修剪装置来修剪未修剪的罐体的开口端的装置，其中每个可修剪装置具有可旋转的第一轴，其具有安装在其上的径向外部或内部刀和滚花辊，用于随其旋转以及第二可旋转轴，其具有径向内部或外部刀和安装在其上的滚花段以与其一起旋转，并且其中，对于转台的每次完整转动，第一轴进行三次完整转动，并且第二轴进行一次完整的转动。此外，提供齿轮的布置用于旋转第一和第二轴。

10. 发明授权

US4976131A Can body making apparatus 失效
标题翻译：罐身制作机
公开(公告)号：US4976131A
公开(公告)日：1990-12-11
申请号：US510622
申请日：1990-04-18
申请人： Conrad M. Grims , Bert E. Johansson , Roger A. Hahn
发明人： Conrad M. Grims , Bert E. Johansson , Roger A. Hahn
IPC分类号： B21D22/30 , B21D51/26
CPC分类号： B21D22/30 , B21D51/26
摘要： A redraw apparatus is provided for a can body making apparatus wherein the redraw carriage of the redraw apparatus is mounted for substantially friction-free sliding reciprocating movement over a pair of spaced apart support posts which are fixedly mounted on the housing holding the can forming and ironing dies. Also, a counterbalancing system is provided for applying a force to counterbalance the weight of a portion of structures used to reciprocate the redraw carriage. Additionally, a raw assembly is provided for supporting a ram for movement through the redraw apparatus and the can forming and ironing dies wherein a pair of spaced apart elongated shafts are fixedly mounted and a ram carriage having the ram attached thereto is provided with liquid bearings using liquid coolant comprising water having solubles contained therein for mounting the ram carriage on the elongated shafts for substantially friction free movement thereover. A guide liquid bearing is also used to ensure proper alignment of the ram. Also disclosed in a reciprocating ram which is supported solely by a liquid bearing wherein the liquid bearing using liquid coolant comprising water having solubles contained therein has a sufficient length to ensure the proper alignment of the leading portion of the elongated ram as it engages a can blank in a redraw assembly and moves it through the forming and ironing dies to form an elongated can body.
摘要翻译：为罐体制造装置提供了一种重画装置，其中重画装置的重新拉出装置安装成用于在一对间隔开的支撑柱上基本上无摩擦的滑动往复运动，固定地安装在保持罐形成和熨烫的壳体上死了而且，还提供了一种平衡系统，用于施加力以平衡用于使重新拉出托架往复移动的结构的一部分的重量。另外，提供了一个原始组件，用于支撑用于移动通过重新拉拔装置的冲头，以及固定地安装一对间隔开的细长轴的罐头成形和熨烫模具，并且具有附接到其上的冲头的冲头滑架设置有液体轴承，其使用液体冷却剂包括其中容纳有可溶物的水，用于将柱塞滑架安装在细长轴上，用于在其上基本上无摩擦力的运动。引导液体轴承也用于确保冲头的正确对准。还公开在仅由液体轴承支撑的往复式推杆中，其中使用包含其中容纳可溶物的水的液体冷却剂的液体轴承具有足够的长度，以确保细长冲头的引导部分在与罐坯体接合时的适当对准在重画组件中并将其移动通过成型和熨烫模具以形成细长的罐体。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式