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1. 发明申请

US20120315639A1 METHOD AND APPARATUS FOR SINGLE CELL ISOLATION AND ANALYSIS 审中-公开
标题翻译：用于单细胞分离和分析的方法和装置
公开(公告)号：US20120315639A1
公开(公告)日：2012-12-13
申请号：US13483422
申请日：2012-05-30
申请人： GLENN YAGUANG DENG , Jie Zhang , Fang Tian
发明人： GLENN YAGUANG DENG , Jie Zhang , Fang Tian
IPC分类号： G01N33/574 , C12Q1/68 , C12M1/42 , G01N33/566
CPC分类号： G01N33/54333 , B03C1/0332 , B03C1/0335 , B03C1/284 , B03C1/286 , B03C1/288 , B03C2201/18 , B03C2201/26 , G01N33/538
摘要： A method and apparatus are disclosed here for rare target cell enrichment and isolation, where the captured target cells can be individually picked up and used for downstream analysis. This method and apparatus utilize antibodies conjugated microbeads to isolate target cells, use ON/OFF controls for the target cell capturing magnet and the release magnet, such that there is no need to change the cap of the capturing magnet and thus enabling automatic multiple rounds of capturing, washing and releasing cycles to increase the target cell detection sensitivity and reproducibility. A special filter is utilized to effectively remove more than 95% of free unbound microbeads, thus significantly improving the purity of the collected target cells and increasing the data quality of downstream analysis of the single target cells. Lastly, RNA expression patterns are proposed for identifying of certain target cells (e.g. circulating tumor cells and white blood cells).
摘要翻译：这里公开了用于稀有靶细胞富集和分离的方法和装置，其中捕获的靶细胞可以单独拾取并用于下游分析。该方法和装置利用抗体缀合的微珠来分离靶细胞，使用靶细胞捕获磁体和释放磁体的ON / OFF控制，使得不需要改变捕获磁体的盖，因此使得能够自动多轮捕获，洗涤和释放循环以增加靶细胞检测灵敏度和再现性。利用特殊的过滤器有效去除95％以上的游离的未结合微珠，从而显着提高收集靶细胞的纯度，提高单靶细胞下游分析的数据质量。最后，提出RNA表达模式用于鉴定某些靶细胞（例如循环肿瘤细胞和白细胞）。

2. 发明申请

US20090303070A1 Distributed Decision Making Area Earthquake Warning System 审中-公开
标题翻译：分布式决策区地震预警系统
公开(公告)号：US20090303070A1
公开(公告)日：2009-12-10
申请号：US12136289
申请日：2008-06-10
申请人： Jie Zhang , Yu Han , Fang Tian
发明人： Jie Zhang , Yu Han , Fang Tian
IPC分类号： G08B21/00
CPC分类号： G08B27/00 , G08B21/10
摘要： An improved area earthquake warning system based on distributed decision making method, which makes such a system affordable in the region where wired and wireless mobile communication infrastructures are too expensive to build. The present invention can provide seconds, even tens of seconds for users to seek shelter to reduce injuries and lives lost. An exemplary embodiment of the invention described herein comprises a network of earthquake detection sites covering a geographic region with four types of earthquake detection sites. Instead of sending all raw ground motion signals to a remote central processing site, these detection sites send processed earthquake parameters to a nearby alarm site to decide if an earthquake alarm broadcasting should be triggered. This method shortens the response time, decreases the false alarm rate, and provides unlimited scalability. Further more, this invention provides self-check mechanism to eliminate system malfunction time.
摘要翻译：一种基于分布式决策方法的改进型地震预警系统，使得有线和无线移动通信基础设施建设成本高昂的地区实现了这种系统的价格。本发明可以为用户提供几秒甚至几十秒的时间来寻求避难所，减少伤害和生命损失。本文描述的本发明的示例性实施例包括覆盖具有四种类型的地震检测位置的地理区域的地震检测站点的网络。这些检测站点不是将所有原始地面运动信号发送到远程中央处理站点，而是将处理过的地震参数发送到附近的报警站点，以决定是否触发地震报警广播。该方法缩短响应时间，降低误报率，提供无限可扩展性。此外，本发明提供了自检机制，以消除系统故障时间。

3. 发明授权

US08422216B2 Memory holding apparatus 失效
标题翻译：记忆保持装置
公开(公告)号：US08422216B2
公开(公告)日：2013-04-16
申请号：US12960353
申请日：2010-12-03
申请人： Zhi-Chun Liang , Fang Tian
发明人： Zhi-Chun Liang , Fang Tian
IPC分类号： G06F1/16
CPC分类号： G06F1/183
摘要： A memory holding apparatus includes a main pole and an inserting pole. The main pole includes a main portion and a first holding portion perpendicularly extending from a first end of the main portion. A second end of the main portion defines a receiving hole extending to the first holding portion. A sidewall of the main portion defines an opening. An elastic blocking piece extends from a side bounding the opening. A hook extends from an inside wall of the blocking piece. The inserting pole includes an inserting portion and a second holding portion perpendicularly extending from a first end of the inserting portion. The inserting portion defines a groove from a second end of the inserting portion extending to the second holding portion. A number of blocks extend from a bottom of the groove. The hook is selectively engaged with one of the blocks.
摘要翻译：存储器保持装置包括主极和插入杆。主杆包括主要部分和从主要部分的第一端垂直延伸的第一保持部分。主要部分的第二端限定延伸到第一保持部分的接收孔。主要部分的侧壁限定开口。弹性阻挡件从限定开口的一侧延伸。钩从阻塞件的内壁延伸。插入杆包括插入部分和从插入部分的第一端垂直延伸的第二保持部分。插入部分从延伸到第二保持部分的插入部分的第二端限定凹槽。多个块从凹槽的底部延伸。钩子选择性地与其中一个块接合。

4. 发明申请

US20100215544A1 HANDHELD MICROCANTILEVER-BASED SENSOR FOR DETECTING TOBACCO-SPECIFIC NITROSAMINES 审中-公开
标题翻译：用于检测烟草特异性硝基苯胺的手持式麦克风传感器
公开(公告)号：US20100215544A1
公开(公告)日：2010-08-26
申请号：US12769338
申请日：2010-04-28
申请人： Seetharama C. Deevi , Fang Tian
发明人： Seetharama C. Deevi , Fang Tian
IPC分类号： B01J19/00 , H01L41/22
CPC分类号： G01N29/022 , G01N33/0047 , G01N2291/0255 , G01N2291/0256 , Y10T436/170769
摘要： A method and system for detecting tobacco-specific nitrosamines. The method includes exposing at least one microcantilever beam to a medium, which may contain tobacco-specific nitrosamines, and measuring a deflection of the microcantilever beam, wherein the deflection indicates a presence of tobacco-specific nitrosamines in the medium. The at least one microcantilever beam can include a silicon base layer and a gold-coated receptor layer with a plurality of thiol molecules having a sulfur head and carboxyl-terminated group. The at least one microcantilever beam can include a silicon base layer and a metal or metal oxide coated receptor layer. Alternatively, the microcantilever beam can be formed by co-absorbing tobacco-specific nitrosamines and silane molecules on a silicon microcantilever surface, wherein the template molecules of tobacco-specific nitrosamines physically co-adsorb between the silane molecules. The template molecules of tobacco-specific nitrosamines are then washed away with a solvent to form a silane monolayer having tobacco-specific nitrosamine cavities.
摘要翻译：一种用于检测烟草特异性亚硝胺的方法和系统。该方法包括将至少一个微悬臂梁暴露于介质中，该培养基可含有烟草特异性亚硝胺，并测量微悬臂梁的挠曲，其中偏转指示介质中烟草特异性亚硝胺的存在。所述至少一个微悬臂梁可以包括具有硫头和羧基封端基团的多个硫醇分子的硅基层和金涂覆的受体层。所述至少一个微悬臂梁可以包括硅基层和金属或金属氧化物涂覆的受体层。或者，可以通过在硅微悬臂梁表面上共同吸收烟草特异性亚硝胺和硅烷分子来形成微悬臂梁，其中烟草特异性亚硝胺的模板分子物理共吸附在硅烷分子之间。然后用溶剂洗涤烟草特异性亚硝胺的模板分子以形成具有烟草特异性亚硝胺腔的硅烷单层。

5. 发明授权

US09516988B2 Water spraying apparatus of dishwasher and dishwasher comprising the same 有权
标题翻译：洗碗机和洗碗机的喷水装置包括其
公开(公告)号：US09516988B2
公开(公告)日：2016-12-13
申请号：US14343337
申请日：2012-09-07
申请人： Weidong Zhao , Fang Tian
发明人： Weidong Zhao , Fang Tian
IPC分类号： F16L27/08 , A47L15/42 , A47L15/23
CPC分类号： A47L15/4278 , A47L15/23 , F16L27/0804 , F16L27/0849
摘要： A water spraying apparatus of a dishwasher and the dishwasher comprising the water spraying apparatus are provided. The water spraying apparatus comprises a water source connecting pipe having a water outlet tube, a spraying arm having a water inlet tube, and a connecting device connecting the water source connecting pipe with the spraying arm, in which the connecting device comprises first and second semicircular fitting rings which are adapted to snap-fit with each other to form a connecting ring, the connecting ring is rotatably fitted over the water outlet tube of the water source connecting pipe and positioned in an axial direction of the connecting ring between the water inlet tube of the spraying arm and the water outlet tube of the water source connecting pipe.
摘要翻译：提供了一种洗碗机的喷水装置和包括喷水装置的洗碗机。喷水装置包括具有出水管的水源连接管，具有进水管的喷射臂和将水源连接管与喷射臂连接的连接装置，其中连接装置包括第一和第二半圆所述连接环适于彼此卡扣配合以形成连接环，所述连接环可旋转地装配在所述水源连接管的出水管上，并且在所述连接环的轴向方向上位于所述进水管的喷水臂和水源连接管的出水管。

6. 发明申请

US20080145998A1 METHOD OF FORMING A LOW-K DUAL DAMASCENE INTERCONNECT STRUCTURE 失效
标题翻译：形成低K双重DAMASCENE互连结构的方法
公开(公告)号：US20080145998A1
公开(公告)日：2008-06-19
申请号：US11531493
申请日：2006-09-13
申请人： GERARDO A. DELGADINO , Yan Ye , Neungho Shin , Yunsang Kim , Li-Qun Xia , Tzu-Fang Huang , Lihua Li Huang , Joey Chiu , Xiaoye Zhao , Fang Tian , Wen Zhu , Ellie Yieh
发明人： GERARDO A. DELGADINO , Yan Ye , Neungho Shin , Yunsang Kim , Li-Qun Xia , Tzu-Fang Huang , Lihua Li Huang , Joey Chiu , Xiaoye Zhao , Fang Tian , Wen Zhu , Ellie Yieh
IPC分类号： H01L21/76
CPC分类号： H01L21/76826 , H01L21/76811 , H01L21/76813
摘要： A method of fabricating an interconnect structure comprising etching a via into an upper low K dielectric layer and into a hardened portion of a lower low K dielectric layer. The via is defined by a pattern formed in a photoresist layer. The photoresist layer is then stripped, and a trench that circumscribes the via as defined by a hard mask is etched into the upper low K dielectric layer and, simultaneously, the via that was etched into the hardened portion of the lower low K dielectric layer is further etched into the lower low K dielectric layer. The result is a low K dielectric dual damascene structure.
摘要翻译：一种制造互连结构的方法，包括将通孔蚀刻到上部低K电介质层中并进入下部低K电介质层的硬化部分。通孔由形成在光致抗蚀剂层中的图案限定。然后剥离光致抗蚀剂层，并且将由硬掩模限定的通孔的沟槽蚀刻到上部低K电介质层中，并且同时蚀刻到下部低K电介质层的硬化部分中的通孔是进一步蚀刻到下部低K介电层中。结果是低K电介质双镶嵌结构。

7. 发明申请

US20080102532A1 Handheld microcantilever-based sensor for detecting tobacco-specific nitrosamines 有权
标题翻译：用于检测烟草特异性亚硝胺的手持式微型悬臂梁传感器
公开(公告)号：US20080102532A1
公开(公告)日：2008-05-01
申请号：US11902041
申请日：2007-09-18
申请人： Seetharama Deevi , Fang Tian
发明人： Seetharama Deevi , Fang Tian
IPC分类号： G01N33/00 , B01J19/00 , B05D1/36 , B05D3/10
CPC分类号： G01N29/022 , G01N33/0047 , G01N2291/0255 , G01N2291/0256 , Y10T436/170769
摘要： A method and system for detecting tobacco-specific nitrosamines. The method includes exposing at least one microcantilever beam to a medium, which may contain tobacco-specific nitrosamines, and measuring a deflection of the microcantilever beam, wherein the deflection indicates a presence of tobacco-specific nitrosamines in the medium. The at least one microcantilever beam can include a silicon base layer and a gold-coated receptor layer with a plurality of thiol molecules having a sulfur head and carboxyl-terminated group. The at least one microcantilever beam can include a silicon base layer and a metal or metal oxide coated receptor layer. Alternatively, the microcantilever beam can be formed by co-absorbing tobacco-specific nitrosamines and silane molecules on a silicon microcantilever surface, wherein the template molecules of tobacco-specific nitrosamines physically co-adsorb between the silane molecules. The template molecules of tobacco-specific nitrosamines are then washed away with a solvent to form a silane monolayer having tobacco-specific nitrosamine cavities.
摘要翻译：一种用于检测烟草特异性亚硝胺的方法和系统。该方法包括将至少一个微悬臂梁暴露于介质中，该培养基可含有烟草特异性亚硝胺，并测量微悬臂梁的挠曲，其中偏转指示介质中烟草特异性亚硝胺的存在。所述至少一个微悬臂梁可以包括具有硫头和羧基封端基团的多个硫醇分子的硅基层和金涂覆的受体层。所述至少一个微悬臂梁可以包括硅基层和金属或金属氧化物涂覆的受体层。或者，可以通过在硅微悬臂梁表面上共同吸收烟草特异性亚硝胺和硅烷分子来形成微悬臂梁，其中烟草特异性亚硝胺的模板分子物理共吸附在硅烷分子之间。然后用溶剂洗涤烟草特异性亚硝胺的模板分子以形成具有烟草特异性亚硝胺腔的硅烷单层。

8. 发明授权

US07132369B2 Method of forming a low-K dual damascene interconnect structure 失效
标题翻译：形成低K双镶嵌互连结构的方法
公开(公告)号：US07132369B2
公开(公告)日：2006-11-07
申请号：US10745344
申请日：2003-12-22
申请人： Gerardo A. Delgadino , Yan Ye , Neungho Shin , Yunsang Kim , Li-Qun Xia , Tzu-Fang Huang , Lihua Li , Joey Chiu , Xiaoye Zhao , Fang Tian , Wen Zhu , Ellie Yieh
发明人： Gerardo A. Delgadino , Yan Ye , Neungho Shin , Yunsang Kim , Li-Qun Xia , Tzu-Fang Huang , Lihua Li , Joey Chiu , Xiaoye Zhao , Fang Tian , Wen Zhu , Ellie Yieh
IPC分类号： H01L21/302
CPC分类号： H01L21/76826 , H01L21/76811 , H01L21/76813
摘要： A method of fabricating an interconnect structure comprising etching a via into an upper low K dielectric layer and into a hardened portion of a lower low K dielectric layer. The via is defined by a pattern formed in a photoresist layer. The photoresist layer is then stripped, and a trench that circumscribes the via as defined by a hard mask is etched into the upper low K dielectric layer and, simultaneously, the via that was etched into the hardened portion of the lower low K dielectric layer is further etched into the lower low K dielectric layer. The result is a low K dielectric dual damascene structure.
摘要翻译：一种制造互连结构的方法，包括将通孔蚀刻到上部低K电介质层中并进入下部低K电介质层的硬化部分。通孔由形成在光致抗蚀剂层中的图案限定。然后剥离光致抗蚀剂层，并且将由硬掩模限定的通孔的沟槽蚀刻到上部低K电介质层中，并且同时蚀刻到下部低K电介质层的硬化部分中的通孔为进一步蚀刻到下部低K介电层中。结果是低K电介质双镶嵌结构。

9. 发明申请

US20140299683A1 WATER SPRAYING APPARATUS OF DISHWASHER AND DISHWASHER COMPRISING THE SAME 有权
标题翻译：洗衣机和洗衣机包装的水喷涂装置
公开(公告)号：US20140299683A1
公开(公告)日：2014-10-09
申请号：US14343337
申请日：2012-09-07
申请人： Weidong Zhao , Fang Tian
发明人： Weidong Zhao , Fang Tian
IPC分类号： A47L15/42
CPC分类号： A47L15/4278 , A47L15/23 , F16L27/0804 , F16L27/0849
摘要： A water spraying apparatus of a diswasher and the diswasher comprising the water spraying apparatus are provided. The water spraying apparatus comprises a water source connecting pipe having a water outlet tube, a spraying arm having a water inlet tube, and a connecting device connecting the water source connecting pipe with the spraying arm, in which the connecting device comprises first and second semicircular fitting rings which are adapted to snap-fit with each other to form a connecting ring, the connecting ring is rotatably fitted over the water outlet tube of the water source connecting pipe and positioned in an axial direction of the connecting ring between the water inlet tube of the spraying arm and the water outlet tube of the water source connecting pipe.
摘要翻译：提供了一种洗碗机的喷水装置和包括喷水装置的洗涤机。喷水装置包括具有出水管的水源连接管，具有进水管的喷射臂和将水源连接管与喷射臂连接的连接装置，其中连接装置包括第一和第二半圆所述连接环适于彼此卡扣配合以形成连接环，所述连接环可旋转地装配在所述水源连接管的出水管上，并且在所述连接环的轴向方向上位于所述进水管的喷水臂和水源连接管的出水管。

10. 发明授权

US08769314B2 Test fixture and method using the DTR pins and CTS pins of RS-232 connectors for automatically turning on computers 有权
标题翻译：使用RS-232连接器的DTR引脚和CTS引脚测试夹具和方法，自动打开计算机
公开(公告)号：US08769314B2
公开(公告)日：2014-07-01
申请号：US12857577
申请日：2010-08-17
申请人： Zhi-Chun Liang , Jun-Min Chen , Zhi-Jian Long , Fang Tian
发明人： Zhi-Chun Liang , Jun-Min Chen , Zhi-Jian Long , Fang Tian
IPC分类号： G06F1/00 , G01D3/00 , H01H31/02
CPC分类号： G06F1/26
摘要： A test fixture includes a first RS-232 connector and a second RS-232 connector. The data terminal ready (DTR) pin of the first RS-232 connector is connected to the DTR pin of the second RS-232 connector, and the clear to send (CTS) pin of the first RS-232 connector is connected to the CTS pin of the second RS-232 connector. The DTR pins are further connected to a power pin of each of the test computers. The test fixture sets a high level voltage for the connected DTR pins, and sets a low level voltage for the connected CTS pins according to the commands of turning on the test computers sent by the control computer, to turn on the test computers. An auto shutdown software included in each of the test computers is executed to shut down the test computers.
摘要翻译：测试夹具包括第一个RS-232连接器和第二个RS-232连接器。第一个RS-232连接器的数据终端就绪（DTR）引脚连接到第二个RS-232连接器的DTR引脚，第一个RS-232连接器的清除发送（CTS）引脚连接到CTS 第二个RS-232连接器的引脚。 DTR引脚进一步连接到每个测试计算机的电源引脚。测试夹具为连接的DTR引脚设置高电平电压，并根据打开控制计算机发送的测试计算机的命令为连接的CTS引脚设置低电平电压，以打开测试计算机。执行每个测试计算机中包括的自动关机软件以关闭测试计算机。

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