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1. 发明申请

US20060069749A1 Location enhanced information delivery system 审中-公开
公开(公告)号：US20060069749A1
公开(公告)日：2006-03-30
申请号：US10369057
申请日：2003-02-17
申请人： Frederick Herz , Jonathan Smith , David Parkes
发明人： Frederick Herz , Jonathan Smith , David Parkes
IPC分类号： G06F15/16 , G06F17/30 , G06F7/00 , G06F17/00
CPC分类号： G06Q30/02 , G06F16/9535 , G06F16/9537 , H04W8/18
摘要： The Location Enhanced Information Deliver System Architecture (LEIA) customizes the information that is displayed to an information recipient based on optimizing a match between information purveyors, such as advertisers, and the information recipients who are local to an information delivery system. The present location enhanced information delivery system presents the information most suited to the real current audience, as measured by location information systems, rather than to a static predicted audience. While the preferred embodiment discloses a beaconing-style wireless technology, the system concept is easily extensible both to other location-information systems, such as license-plate scanning with cameras, and to utilizing the location-information for private displays of information in addition to public displays of information.

2. 发明申请

US20070008927A1 Autoband 有权
标题翻译：自动频带
公开(公告)号：US20070008927A1
公开(公告)日：2007-01-11
申请号：US11412600
申请日：2006-04-26
申请人： Frederick Herz , Jonathan Smith , Bhupinder Madan
发明人： Frederick Herz , Jonathan Smith , Bhupinder Madan
IPC分类号： H04Q7/00
CPC分类号： H04W84/18 , H04B7/18506 , H04L45/00 , H04L45/22 , H04L45/30 , H04W40/12 , H04W40/18 , H04W40/20 , H04W40/24 , H04W72/04 , H04W84/12
摘要： Autoband's distributed networking intelligence provides a novel architecture capable of dynamically reconfiguring communications pathways consisting of links whose transmission media are opportunistically and dynamically selectable. At least one constituent node in such automatically configurable transient pathways is mobile, for example, information (source) server, intervening router node(s), gateway server and/or client device. Additionally, Autoband's ad hoc communications pathways may seamlessly and dynamically integrate (i.e., “graft”) into standard fixed node networks such as terrestrial networks, other wireless networks or combinations thereof. These communications may consist of point-to-point or multicast links. An economic market-based approach further assures allocation of available network resources (i.e., bandwidth and processing) needed to achieve the most optimally resource efficient communications pathway configurations for the totality of communications. Consequently, optimal network resource allocation and efficiency at a system-wide level is continuously achieved.
摘要翻译： Autoband的分布式网络智能提供了一种新颖的架构，能够动态地重新配置由传输媒介机会主义和动态选择的链路组成的通信路径。这种自动配置的瞬时路径中的至少一个组成节点是移动的，例如信息（源）服务器，中间路由器节点，网关服务器和/或客户端设备。此外，Autoband的自组织通信路径可以无缝地和动态地整合（即，“移植”）到诸如地面网络，其他无线网络或其组合的标准固定节点网络中。这些通信可以由点对点或多播链路组成。基于经济市场的方法进一步确保为整体通信实现最佳资源有效的通信路径配置所需的可用网络资源（即，带宽和处理）的分配。因此，不断实现系统级的最优网络资源配置和效率。

3. 发明申请

US20060052142A1 Mobile link selection method for establishing highly efficient communications between mobile devices 有权
标题翻译：用于在移动设备之间建立高效通信的移动链路选择方法
公开(公告)号：US20060052142A1
公开(公告)日：2006-03-09
申请号：US10205182
申请日：2002-11-12
申请人： Frederick Herz , Jonathan Smith
发明人： Frederick Herz , Jonathan Smith
IPC分类号： H04M1/00
CPC分类号： H04B1/406
摘要： The present invention provides a new solution to reliable communication between automobiles and other communications devices. It relies on multiple available wireless bands and the addition of significant memory buffering to automobiles. The memory buffering is used to enable a new communications model for messages that we call Mobile Message Memory Queues (M3Qs). A significant benefit of the disclosed invention is the ease in which it can be incorporated into an automobile.
摘要翻译：本发明提供了一种用于汽车和其他通信设备之间的可靠通信的新解决方案。它依赖于多个可用的无线频带，并为汽车添加显着的内存缓冲。存储器缓冲用于为我们称为移动消息存储器队列（M 3 Q）的消息启用新的通信模型。所公开的发明的显着优点在于可以将其并入汽车中。

4. 外观设计

USD738969S1 Fitness device 有权
标题翻译：健身器材
公开(公告)号：USD738969S1
公开(公告)日：2015-09-15
申请号：US29484976
申请日：2014-03-14
申请人： Jonathan Smith
设计人： Jonathan Smith

5. 发明申请

US20130177551A1 RISK MARKERS FOR CARDIOVASCULAR DISEASE 有权
标题翻译：心血管疾病危险标志
公开(公告)号：US20130177551A1
公开(公告)日：2013-07-11
申请号：US13683527
申请日：2012-11-21
申请人： Stanley L. Hazen , Michael Kinter , Marc S. Penn , Jonathan Smith , Lemin Zheng
发明人： Stanley L. Hazen , Michael Kinter , Marc S. Penn , Jonathan Smith , Lemin Zheng
IPC分类号： G01N33/92
CPC分类号： G01N33/561 , C07K16/18 , G01N33/6893 , G01N33/92 , G01N2333/775 , G01N2800/32
摘要： Provided herein methods for determining whether a subject, particularly a human subject, is at risk of developing, having, or experiencing a complication of cardiovascular disease, and methods of treating subjects who are identified by the current methods of being at risk for cardiovascular disease. In one embodiment, the method comprises determining levels of one or more oxidized apolipoprotien A-I related biomolecules in a bodily sample from the subject. Also, provided are kits and reagents for use in the present methods. Also provided are methods for monitoring the status of cardiovascular disease in a subject or the effects of therapeutic agents on subjects with cardiovascular disease. Such method comprising determining levels of one or more oxidized apolipoprotein A-I related molecules in bodily samples taken from the subject over time or before and after therapy.
摘要翻译：本文提供用于确定受试者，特别是人类受试者是否处于发展，具有或经历心血管疾病并发症的风险的方法，以及治疗由目前的心血管疾病风险的方法鉴定的受试者的方法。在一个实施方案中，该方法包括确定来自受试者的身体样品中一种或多种氧化的载脂蛋白A-I相关生物分子的水平。此外，提供了用于本方法的试剂盒和试剂。还提供了用于监测受试者心血管疾病状态或治疗剂对心血管疾病受试者的影响的方法。这种方法包括测定在受试者随时间或治疗之前或之后取自受试者的身体样品中一种或多种氧化的载脂蛋白A-1相关分子的水平。

6. 发明申请

US20120095377A1 MULTI-FIT ORTHOTIC AND MOBILITY ASSISTANCE APPARATUS 有权
标题翻译：多功能运动和移动辅助装置
公开(公告)号：US20120095377A1
公开(公告)日：2012-04-19
申请号：US13274109
申请日：2011-10-14
申请人： Jonathan Smith , Kern Bhugra
发明人： Jonathan Smith , Kern Bhugra
IPC分类号： A61F5/00
CPC分类号： A61F5/0125 , A61F5/0102
摘要： A multi-fit orthotic structure including an attachment system for coupling the orthotic structure to a wide variety of subjects without requiring a custom fit. In one embodiment, active mobility assistance is provided via an orthotic system capable of integrating a linear actuator and linkage system to deliver torque to the lower leg of a subject to facilitate flexion and/or extension motion of the subject's leg. The orthotic structure is attached to the subject using a textile suspension system which does not require the orthotic structure to interface directly in the knee region or at the lateral areas of the thigh and calf of the subject, thus providing an ideal fit for the widest possible range of subjects with the minimum number of required sizes.
摘要翻译：一种多合适矫形器结构，包括用于将矫形器结构与各种各样的受试者联接而不需要定制配合的附接系统。在一个实施例中，通过能够集成线性致动器和联动系统的矫正系统来提供主动移动辅助，以将扭矩传递到对象的小腿，以促进对象腿部的屈曲和/或伸展运动。使用不需要矫正结构的纺织品悬挂系统将矫形器结构附接到受试者，膝关节区域或受试者的大腿和小腿的横向区域直接相接，从而为最广泛的可能性提供理想的适合具有所需尺寸最小数量的科目范围。

7. 发明申请

US20060251681A1 Methods for producing Marburg Virus proteins 失效
标题翻译：生产马尔堡病毒蛋白的方法
公开(公告)号：US20060251681A1
公开(公告)日：2006-11-09
申请号：US11485158
申请日：2006-07-12
申请人： Michael Heyey , Diane Negley , Peter Pushko , Jonathan Smith , Alan Schmaljohn
发明人： Michael Heyey , Diane Negley , Peter Pushko , Jonathan Smith , Alan Schmaljohn
IPC分类号： A61K39/395 , A61K39/12
CPC分类号： C07K14/005 , A61K38/00 , A61K39/00 , A61K2039/5256 , A61K2039/53 , C07K16/10 , C12N7/00 , C12N15/86 , C12N2760/14022 , C12N2760/14222 , C12N2770/36021 , C12N2770/36122 , C12N2770/36123 , C12N2770/36143 , C12N2770/36162
摘要： Using the MBGV GP, NP, and virion proteins, a method and composition for use in inducing an immune response which is protective against infection with MBGV in nonhuman primates is described.
摘要翻译：描述了使用MBGV GP，NP和病毒粒子蛋白，用于诱导免疫应答的方法和组合物，其在非人灵长类动物中防止MBGV感染。

8. 发明授权

US07059925B2 Life preserver system 有权
标题翻译：救生员系统
公开(公告)号：US07059925B2
公开(公告)日：2006-06-13
申请号：US11037433
申请日：2005-01-18
申请人： Jonathan Smith , Michael O'Connell
发明人： Jonathan Smith , Michael O'Connell
IPC分类号： B63C9/08
CPC分类号： B63C9/1255
摘要： An inflatable life preserver, capable of being in an inflated state and an uninflated state, is disclosed. The life preserver includes a structural overshell which defines the size and shape of the life preserver in the inflated state and a gas retention bladder fitted within the overshell. The overshell bears the expansion force of a gas within the bladder in the inflated state. The overshell defines inflatable side portions which are confined to sides of at least a portion of a chest area of a wearer, when the life preserver is in an uninflated state, and, which extend laterally over the chest area of the wearer, when the life preserver is in an inflated state.
摘要翻译：公开了一种能够处于充气状态和未充气状态的充气救生衣。救生员包括一个结构性的外壳，其定义了处于膨胀状态的救生衣的尺寸和形状以及安装在外壳内的保气囊。外壳在膨胀状态下承受膀胱内的气体的膨胀力。所述外壳限定了可膨胀的侧部，其限制在穿用者的胸部区域的至少一部分的侧面，当救生员处于未充气状态时，并且在使用者的胸部区域横向延伸时，防腐剂处于充气状态。

9. 发明申请

US20060057573A1 Methods and reagents for detecting target binding by nucleic acid ligands 审中-公开
标题翻译：用于检测核酸配体靶结合的方法和试剂
公开(公告)号：US20060057573A1
公开(公告)日：2006-03-16
申请号：US10504696
申请日：2003-02-10
申请人： Larry Gold , Jonathan Smith , Dominic Zichi , Daniel Schneider , Chad Greef
发明人： Larry Gold , Jonathan Smith , Dominic Zichi , Daniel Schneider , Chad Greef
IPC分类号： C12Q1/68 , C12Q1/42
CPC分类号： C12N15/115 , G01N33/58
摘要： The present invention provides novel methods and reagents for detecting the binding of protein targets to nucleic acid ligands. Using Universal Protein Stains (UPS), proteins bound by nucleic acid ligands may be labeled with a detectable moiety. The methods and reagents are particularly useful for the detection of protein targets bound to multiplexed arrays of nucleic acid ligands. The present invention also provides novel methods for the multiplexed evaluation of photocrosslinking nucleic acid ligands. The methods allow one simultaneously to: (1) evaluate the performance (dynamic range) of a plurality of photocrosslinking nucleic acid ligands; and (2) assess the specificity of each photocrosslinking nucleic acid ligand for its cognate target protein. Photocrosslinking nucleic acid ligands with the most desirable properties can then be selected for use in diagnostic and prognostic medical assays. The present invention also provides a photocrosslinking nucleic acid ligand that binds specifically to HIV gp120MN.
摘要翻译：本发明提供用于检测蛋白质靶标与核酸配体的结合的新型方法和试剂。使用通用蛋白污渍（UPS），可以用可检测的部分标记由核酸配体结合的蛋白质。所述方法和试剂对于检测与核酸配体复合阵列结合的蛋白质靶标特别有用。本发明还提供了用于光交联核酸配体的多重评价的新方法。该方法同时允许：（1）评估多个光交联核酸配体的性能（动态范围）; 和（2）评估每个光交联核酸配体对其同源靶蛋白的特异性。然后可以选择具有最理想特性的光交联核酸配体用于诊断和预后医学测定。本发明还提供了与HIV gp120MN特异性结合的光交联核酸配体。

10. 发明授权

US06892425B2 Removable door check device 失效
标题翻译：可拆卸门检查装置
公开(公告)号：US06892425B2
公开(公告)日：2005-05-17
申请号：US10358973
申请日：2003-02-05
申请人： Jonathan Smith
发明人： Jonathan Smith
IPC分类号： E05D7/10 , B60J5/04 , E05C17/22 , E05D5/06 , E05D11/10 , E05D11/06
CPC分类号： E05C21/005 , B05B13/0292 , E05D5/062 , E05D11/1014 , E05D11/1085 , E05Y2900/531 , Y10S16/17 , Y10T16/551 , Y10T16/61 , Y10T16/629
摘要： A removable door check device for holding a vehicle door hinge in an opened position includes a body, first and second leg portions extending from the body and disposed coplanar to the body, a protrusion portion extending from the body in a direction perpendicular to the body. In addition, a door hinge that includes a first hinge part, a second hinge part, a hinge pin passing through the first and second hinge parts and a removable door check device. The first and second hinge parts are pivotable about the hinge pin between an opened and a closed position. The removable door check device of the hinge is disposed on the hinge pin exterior to the first and second hinge parts engaging the second hinge part in the opened position.
摘要翻译：用于将车门铰链保持在打开位置的可拆卸的门检查装置包括主体，从主体延伸并且与主体共面设置的第一和第二腿部，从主体沿垂直于主体的方向延伸的突出部分。此外，门铰链包括第一铰链部分，第二铰链部分，穿过第一和第二铰链部分的铰链销和可移除的门检查装置。第一和第二铰链部分可在铰链销之间在打开和关闭位置之间枢转。铰链的可拆卸的门检查装置设置在第一和第二铰链部分的外部的铰链销上，在第二铰链部分处于打开位置。

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