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1. 发明授权

US5846261A Percutaneous catheter directed occlusion devices 失效
标题翻译：经皮导管导向闭塞装置
公开(公告)号：US5846261A
公开(公告)日：1998-12-08
申请号：US925935
申请日：1997-09-08
申请人： Frank Kotula , Kurt Amplatz
发明人： Frank Kotula , Kurt Amplatz
IPC分类号： A61B17/08 , A61B17/00 , A61B17/12 , A61F2/00 , A61F2/01 , A61F2/90
CPC分类号： A61B17/12122 , A61B17/0057 , A61B17/12022 , A61B17/12109 , A61B17/12172 , A61B17/12177 , A61F2/01 , B21F45/008 , A61B2017/00575 , A61B2017/00592 , A61B2017/00606 , A61B2017/00867 , A61F2/90 , A61F2002/016 , A61F2002/30093 , A61F2210/0019 , A61F2230/0006 , A61F2230/0065 , A61F2230/0069 , A61F2230/0071 , A61F2230/0078 , A61F2230/008
摘要： A collapsible medical device and associated methods for occluding an abnormal opening in, for example, a body organ, wherein the medical device is shaped from a heat treatable metal fabric. The metal fabric is formed from a plurality of metal strands and is heat treated within a mold in order to substantially set a desired shape of the device. The medical device includes a fastener for attaching to the end of a guide wire or delivery catheter, wherein the shape of the medical device is formed such that the fastener is attached to the metal fabric within a recess formed in the shape of the medical device. A medical device having a preselected shape is delivered through a catheter or the like for deployment in a desired channel or opening in a patient's body. The medical device may be shaped, for example, to occlude an ASD, PDA, or a VSD.
摘要翻译：一种可折叠的医疗装置和用于阻塞例如身体器官中的异常开口的相关方法，其中所述医疗装置由可热处理的金属织物成形。金属织物由多个金属线形成，并且在模具内进行热处理，以便基本上设定器件的期望形状。医疗装置包括用于附接到导丝或输送导管的端部的紧固件，其中医疗装置的形状形成为使得紧固件在形成为医疗装置形状的凹部内附接到金属织物。具有预选形状的医疗装置通过导管等传送，以展开在患者身体中的期望的通道或开口中。医疗装置可以被成形为例如遮挡ASD，PDA或VSD。

2. 发明授权

US5725552A Percutaneous catheter directed intravascular occlusion devices 失效
标题翻译：经皮导管导管的血管内闭塞装置
公开(公告)号：US5725552A
公开(公告)日：1998-03-10
申请号：US647712
申请日：1996-05-14
申请人： Frank Kotula , Kurt Amplatz , Curtis Amplatz
发明人： Frank Kotula , Kurt Amplatz , Curtis Amplatz
IPC分类号： A61B17/12 , A61B17/00 , A61F2/00 , A61F2/01 , A61F2/90 , A61M25/00 , B21F45/00 , A61B17/08
CPC分类号： A61F2/90 , A61B17/0057 , A61B17/12022 , A61B17/12109 , A61B17/12122 , A61B17/12172 , A61B17/12177 , A61F2/01 , B21F45/00 , B21F45/008 , A61B2017/00526 , A61B2017/00575 , A61B2017/00592 , A61B2017/00606 , A61B2017/00615 , A61B2017/00867 , A61F2/95 , A61F2002/016 , A61F2002/018 , A61F2002/30093 , A61F2210/0019 , A61F2220/0041 , A61F2230/0006 , A61F2230/0069 , A61F2230/0078 , A61F2230/008 , A61F2240/001
摘要： The present invention provides a method of forming a medical device and medical devices which can be formed in accordance with the method. In one embodiment, the method includes the steps of a) providing a metal fabric formed of a plurality of strands formed of a metal which can be heat treated to substantially set a desired shape; b) deforming the metal fabric to generally conform to a surface of a molding element; c) heat treating the metal fabric in contact with the surface of the molding element to substantially set the shape of the fabric in its deformed state; and d) removing the metal fabric from contact with the molding element. The resulting metal fabric will define a medical device which can be collapsed for passage through a catheter or the like for deployment in a channel of a patient's body. Medical devices made in accordance with this method can have varying structures.
摘要翻译：本发明提供一种可以根据该方法形成的医疗装置和医疗装置的形成方法。在一个实施方案中，该方法包括以下步骤：a）提供由多个由金属形成的股线形成的金属织物，该金属纤维可被热处理以基本上设定所需形状; b）使金属织物变形以与模制元件的表面大致相符; c）对与模制元件的表面接触的金属织物进行热处理，以将织物的形状基本上设定在其变形状态; 以及d）去除金属织物与模制元件的接触。所得到的金属织物将限定医疗装置，其可以折叠以通过导管等，以便部署在患者身体的通道中。根据该方法制造的医疗装置可以具有不同的结构。

3. 发明授权

US5098393A Medical introducer and valve assembly 失效
标题翻译：医疗导引器和阀组件
公开(公告)号：US5098393A
公开(公告)日：1992-03-24
申请号：US200662
申请日：1988-05-31
申请人： Kurt Amplatz , Frank Kotula
发明人： Kurt Amplatz , Frank Kotula
IPC分类号： A61M25/06 , A61M39/06
CPC分类号： A61M25/0606 , A61M39/0606 , A61M2025/0687 , A61M2039/062 , A61M2039/0633 , A61M2039/0686
摘要： A medical catheter introducer and hemostasis valve assembly consists of a sheath having an elongated tube defining a conduit, a housing disposed at the proximal end of the sheath and further defining a conduit and an orifice, and a flexible elongated dilator sized for insertion through the hub and sheath conduit. The dilator has a tapered distal tip end and defines an axial conduit and an annular ridge having distally- and proximally-directed inclined surfaces. The sheath, when assembled with the dilator, has its distal end immediately adjacent the proximally-directed inclined surface of the ridge. A hemostasis valve for sealing the conduit is disposed in alignment with the conduit, and defines an aperture for passage of dilator and ridge therethrough in sealing engagement, into the conduit, and seals when the dilator is removed. The valve has a housing defining an orifice of a first diameter, and a valve element of a second diameter, greater than the first diameter. The valve is disposed within the orifice and is subject to externally-applied, radially directed forces that cause the valve to assume a dome-shape formation, with a convex surface disposed against the pressure of fluids within the body. As the introducer assembly is introduced into a body over a guidewire extending via a puncture opening into a vessel, the dilator and sheath flex to follow the guidewire, and the tapered end of the dilator and the distally-directed inclined surface of the ridge act to dilate the flesh about the opening to facilitate passage of the sheath. The introducer and valve may be used alone, or respectively with valves or introducers of other design. A base for attachment of the introducer to the patient is also described.
摘要翻译：医疗导管导引器和止血阀组件包括具有限定导管的细长管的护套，设置在护套的近端处并进一步限定导管和孔的壳体，以及尺寸适于插入穿过毂的柔性细长扩张器和鞘导管。扩张器具有锥形的远端尖端并且限定轴向导管和具有远侧和近侧定向的倾斜表面的环形脊。当与扩张器组装时，护套的远端紧邻脊的向近侧倾斜的表面。用于密封导管的止血阀设置成与管道对准，并且在密封接合时限定了用于使膨胀器和脊通过的孔，用于密封接合，并且当扩张器被移除时密封。阀具有限定第一直径的孔的壳体和大于第一直径的第二直径的阀元件。阀设置在孔内并且受到外部施加的径向力的作用，使得阀呈现穹顶形状，其中凸表面抵抗体内流体的压力设置。当导引器组件被引入到穿过穿刺孔延伸到血管中的导丝上的主体中时，扩张器和皮肤弯曲以跟随导丝，并且扩张器的锥形端和脊的远侧倾斜的表面作用到扩大围绕开口的肉体，以方便鞘的通过。导引器和阀可以单独使用，也可以分别用于其他设计的阀门或导引器。还描述了用于将导引器附接到患者的基部。

4. 发明授权

US4485815A Device and method for fluoroscope-monitored percutaneous puncture treatment 失效
标题翻译：荧光透视监测经皮穿刺治疗的装置和方法
公开(公告)号：US4485815A
公开(公告)日：1984-12-04
申请号：US412594
申请日：1982-08-30
申请人： Kurt Amplatz , Frank Kotula
发明人： Kurt Amplatz , Frank Kotula
IPC分类号： A61B17/34 , A61B19/00
CPC分类号： A61B17/3403 , A61B2017/00902 , A61B90/39
摘要： A device for performing percutaneous puncture treatment of a patient includes an elongate radiolucent plastic handle with a central portion and two opposite elongated end portions. A hollow radiopaque needle has a hub at its proximal end which is releasably mounted in the central portion of the handle so that the needle is perpendicular to an axis through the end portions. The distal end of the needle has a puncturing tip. An internal fluid passage in the needle is open to the tip and the hub so that fluid may be drained from a patient's body through the passage when the needle is inserted in the patient's body. The needle and central portion of the handle are aligned under a field of view of a fluoroscope. The handle is held by the grips which are outside of the field of view of the fluoroscope. While the doctor continuously monitors progress of the needle on the fluoroscope, the puncturing tip is inserted through the skin and moved to an internal location for aspiration of fluid. Medical personnel are safely outside of the field of view of the fluoroscope during the entire process.
摘要翻译：用于对患者进行经皮穿刺治疗的装置包括具有中心部分和两个相对的细长端部的细长的射线可透过塑料手柄。中空的不透射线针在其近端具有轮毂，其可释放地安装在手柄的中心部分中，使得针通过端部垂直于轴线。针的远端具有穿刺尖端。针中的内部流体通道对尖端和轮毂开放，使得当针插入患者体内时，流体可以从患者的身体通过通道排出。手柄的针头和中心部分在荧光镜的视野下对齐。手柄由位于荧光镜视野外的把手握持。当医生连续监测荧光镜上针的进展时，穿刺尖端插入穿过皮肤并移动到内部位置以抽吸流体。在整个过程中，医务人员安全地离开荧光镜的视野。

5. 发明授权

US5171233A Snare-type probe 失效
标题翻译：圈型探头
公开(公告)号：US5171233A
公开(公告)日：1992-12-15
申请号：US514137
申请日：1990-04-25
申请人： Kurt Amplatz , Frank Kotula , Rudy A. Mazzocchi
发明人： Kurt Amplatz , Frank Kotula , Rudy A. Mazzocchi
IPC分类号： A61B17/22 , A61B17/32 , A61F2/00
CPC分类号： A61B17/32056 , A61B17/221 , A61F2002/30093 , A61F2210/0019 , A61M2205/0266
摘要： The present invention provides a snare for intravascular use having an elongate proximal member and a loop-shaped distal segment oriented at an angle to the adjacent portion of the proximal member. The snare may be formed of a superelastic shape memory alloy, which permits the distal segment to be collapsed for passage through a catheter and yet automatically open into its original, unrestrained configuration upon emerging from the distal tip of the catheter.
摘要翻译：本发明提供了一种用于血管内使用的圈套，其具有细长的近端构件和与近端构件的相邻部分成一定角度定向的环形远端区段。网圈可以由超弹性形状记忆合金形成，其允许远端片段被折叠以通过导管，并且当从导管的远侧末端出现时自动地打开到其原始的无限制配置。

6. 发明授权

US4995866A Combined needle and dilator apparatus 失效
标题翻译：组合针和扩张器
公开(公告)号：US4995866A
公开(公告)日：1991-02-26
申请号：US451093
申请日：1989-12-15
申请人： Kurt Amplatz , Frank Kotula
发明人： Kurt Amplatz , Frank Kotula
IPC分类号： A61M5/32 , A61M25/06
CPC分类号： A61M25/0606 , A61M5/3286 , A61M2025/0687
摘要： The present invention provides a combined needle and dilator comprising a needle having a head with an outer diameter greater than the outer diameter of the body of the needle and a dilating sheath carried about the needle and abutting the rearward needle portion of the needle head. The dilating sheath has a front portion with an outer diameter substantially equal to the outer diameter of the needle head to define, with the head, a generally smooth surface; a body portion with an outer diameter greater than that of the front portion; and a tapered portion disposed between the front and body portions. The tapered portion has an outer surface smoothly merging into the outer surfaces of the front portion and the body portion.
摘要翻译：本发明提供了一种组合的针和扩张器，其包括具有头部的针头，所述针头的外径大于所述针体的外径，并且所述扩张鞘围绕所述针头承载并抵靠所述针头的后针部分。扩张鞘具有前部，其外径基本上等于针头的外径，以与头部一起限定大致光滑的表面; 主体部分，其外径大于前部部分的外径; 以及设置在前部和主体部分之间的锥形部分。锥形部分具有平滑地融合到前部和主体部分的外表面中的外表面。

7. 发明授权

US08910613B2 Internal combustion engine 有权
标题翻译：内燃机
公开(公告)号：US08910613B2
公开(公告)日：2014-12-16
申请号：US14212878
申请日：2014-03-14
申请人： Kurt Amplatz
发明人： Kurt Amplatz
IPC分类号： F02B41/00 , F02B75/02 , F02B19/16
CPC分类号： F02B19/16 , Y02T10/125
摘要： An internal combustion engine is described that includes an expansion cylinder adjacent to a first combustion cylinder (or power cylinder). Combustion gases from the first cylinder are directed to the expansion cylinder to act on the piston in the expansion cylinder. The expansion cylinder has a larger bore (i.e. larger diameter piston) and/or a longer stroke than the first cylinder. The longer stroke also results in a much larger crankshaft arm resulting in a significantly improved mechanical advantage (i.e. torque). In addition, the expansion cylinder includes a check valve that is designed to automatically open the expansion chamber to atmosphere if a negative pressure develops due to the varying amount of exhaust gases at different speeds. In one embodiment, two power cylinders can be connected to one expansion cylinder.
摘要翻译：描述了一种内燃机，其包括与第一燃烧气缸（或动力气缸）相邻的膨胀气缸。来自第一气缸的燃烧气体被引导到膨胀气缸以作用在膨胀气缸中的活塞上。膨胀缸具有比第一气缸更大的孔（即更大直径的活塞）和/或更长的冲程。较长的行程也会导致更大的曲轴臂导致显着改善的机械优点（即扭矩）。此外，膨胀气缸包括止回阀，该止回阀被设计成如果由于不同速度的废气的变化量而产生负压，则自动将膨胀室打开到大气中。在一个实施例中，两个动力缸可以连接到一个膨胀缸。

8. 发明授权

US08900287B2 Intravascular deliverable stent for reinforcement of abdominal aortic aneurysm 有权
标题翻译：血管内输送支架用于加强腹主动脉瘤
公开(公告)号：US08900287B2
公开(公告)日：2014-12-02
申请号：US11331640
申请日：2006-01-13
申请人： Kurt Amplatz , John Oslund , Patrick Russo
发明人： Kurt Amplatz , John Oslund , Patrick Russo
IPC分类号： A61F2/06 , A61F2/07 , A61F2/90
CPC分类号： A61F2/07 , A61F2/852 , A61F2/856 , A61F2/90 , A61F2002/061 , A61F2002/075 , A61F2210/0014 , A61F2250/0015 , D04C1/06 , D10B2401/046 , D10B2509/06
摘要： A stent/graft especially designed to be used in a minimally invasive surgical procedure for treating an abdominal aortic aneurysm (AAA) comprises an innermost tubular structure of a length (L1) formed by braiding a relatively few strands of shape memory alloy wire. The pick and pitch of the braid are such as to provide relative large fenestrations in the tubular wall. A portion of the innermost tubular structure of a length L2 L2 does not block blood flow to the renal arteries while the portion L2 prevents the aneurysm to grown and burst.
摘要翻译：特别设计用于治疗腹主动脉瘤（AAA）的微创外科手术中的支架/移植物包括通过编织相对较少的形状记忆合金线束形成的长度（L1）的最内管状结构。编织物的拣选和间距在管状壁中提供相对较大的开窗。长度为L2 L2不阻止血液流向肾动脉，同时部分L2防止动脉瘤生长并爆裂。

9. 发明授权

US08778008B2 Intravascular deliverable stent for reinforcement of vascular abnormalities 有权
标题翻译：血管内输送支架用于加强血管异常
公开(公告)号：US08778008B2
公开(公告)日：2014-07-15
申请号：US11654288
申请日：2007-01-17
申请人： Kurt Amplatz , John C. Oslund , Patrick Russo , Xiaoping Gu
发明人： Kurt Amplatz , John C. Oslund , Patrick Russo , Xiaoping Gu
IPC分类号： A61F2/06 , A61F2/82 , A61F2/852
CPC分类号： A61F2/82 , A61F2/07 , A61F2/852 , A61F2/90 , A61F2002/075 , A61F2002/823 , A61F2210/0014 , A61F2210/0076 , A61F2220/0008 , A61F2220/0041 , A61F2220/0075 , A61F2250/0015 , A61F2250/0023 , A61F2250/0037
摘要： A catheter deliverable stent/graft especially designed to be used in a minimally invasive surgical procedure for treating a variety of vascular conditions such as aneurysms, stenotic lesions and saphenous vein grafts, comprises an innermost tubular structure and at least one further tubular member in coaxial arrangement. In one embodiment, the innermost tubular structure is of a length (L1) and is formed by braiding a relatively few strands of highly elastic metallic alloy. The pick and pitch of the braid are such as to provide relative large fenestrations in the tubular wall that permit blood flow through the wall and provide the primary radial support structure. A portion of the innermost tubular structure of a length L1 is surrounded by a further braided tubular structure having relatively many strands that substantially inhibit blood flow through the fenestrations of the innermost tubular structure. The composite structure can be stretched to reduce the outer diameter of the stent/graft, allowing it to be drawn into a lumen of a delivery catheter. The catheter can then be advanced through the vascular system to the site of treatment and then released, allowing it to self-expand against the vessel wall. Various optional embodiments are disclosed that allow one skilled in the art to tailor the design to the specific application.
摘要翻译：特别设计用于治疗各种血管病变如动脉瘤，狭窄病变和隐静脉移植物的微创外科手术中的导管可输送支架/移植物包括最内管状结构和至少一个同轴布置的另外的管状构件。在一个实施例中，最内管状结构具有长度（L1），并且通过编织相对较少数量的高弹性金属合金而形成。编织物的拣选和间距是在管状壁中提供允许血液流过壁并提供初级径向支撑结构的相对较大的开窗。长度为L1的最内管状结构的一部分由具有相当多的股线的进一步的编织管状结构包围，其基本上抑制通过最内管状结构的开窗的血液流动。复合结构可被拉伸以减小支架/移植物的外径，使其能够被拉入输送导管的内腔。导管然后可以通过血管系统前进到治疗部位，然后释放，允许其自我扩张抵靠血管壁。公开了各种可选实施例，其允许本领域技术人员根据具体应用来定制设计。

10. 发明授权

US08398670B2 Multi-layer braided structures for occluding vascular defects and for occluding fluid flow through portions of the vasculature of the body 有权
标题翻译：用于阻塞血管缺陷并阻塞流体流过身体脉管系统部分的多层编织结构
公开(公告)号：US08398670B2
公开(公告)日：2013-03-19
申请号：US11473971
申请日：2006-06-23
申请人： Kurt Amplatz , Xiaoping Gu , John C. Oslund , Gary A. Thill
发明人： Kurt Amplatz , Xiaoping Gu , John C. Oslund , Gary A. Thill
IPC分类号： A61M29/00
CPC分类号： A61B17/0057 , A61B17/12022 , A61B17/12122 , A61B17/12172 , A61B2017/00575 , A61B2017/00592 , A61B2017/00606 , A61B2017/00867
摘要： A collapsible medical device and associated methods of occluding an abnormal opening in, for example, a body organ, wherein the medical device is shaped from plural layers of a heat-treatable metal fabric. Each of the fabric layers is formed from a plurality of metal strands and the assembly is heat-treated within a mold in order to substantially set a desired shape of the device. By incorporating plural layers in the thus-formed medical device, the ability of the device to rapidly occlude an abnormal opening in a body organ is significantly improved.
摘要翻译：一种可折叠的医疗装置和在例如身体器官中闭塞异常开口的相关方法，其中所述医疗装置由多层可热处理的金属织物成形。每个织物层由多个金属线形成，并且该组件在模具内进行热处理，以便基本上设置该装置的期望形状。通过在如此形成的医疗装置中并入多层，显着提高了装置快速闭塞体内器官的异常开口的能力。

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