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1. 发明授权

US09272280B2 Device, systems and methods for evaluation of hemostasis 有权
标题翻译：用于止血评估的装置，系统和方法
公开(公告)号：US09272280B2
公开(公告)日：2016-03-01
申请号：US13397398
申请日：2012-02-15
申请人： Francesco Viola , William F. Walker , Gregory V. Browne , Robert S. Magyar , Bjarne Hansen , Christopher G. Denny , Karen Platt
发明人： Francesco Viola , William F. Walker , Gregory V. Browne , Robert S. Magyar , Bjarne Hansen , Christopher G. Denny
IPC分类号： G01N30/96 , B01L3/00 , G01N35/00
CPC分类号： G01N33/86 , B01L3/5027 , B01L3/502761 , B01L3/527 , B01L2200/04 , B01L2200/0647 , B01L2300/02 , B01L2300/024 , B01L2300/027 , B01L2300/0627 , B01L2300/0654 , B01L2300/0681 , B01L2300/0816 , B01L2300/0829 , B01L2300/0861 , B01L2300/0864 , B01L2300/0867 , B01L2300/123 , B01L2300/14 , B01L2300/16 , B01L2300/1805 , B01L2400/0436 , B01L2400/0439 , B01L2400/0487 , B01L2400/049 , B01L2400/0666 , G01N29/024 , G01N29/222 , G01N35/00 , G01N2800/224
摘要： Provided are devices, systems and methods for evaluation of hemostasis. Also provided are sound focusing assemblies.
摘要翻译：提供了用于止血评估的装置，系统和方法。还提供声音聚焦组件。

2. 发明申请

US20120329082A1 Devices, Systems and Methods For Evaluation of Hemostasis 有权
标题翻译：用于评估止血的装置，系统和方法
公开(公告)号：US20120329082A1
公开(公告)日：2012-12-27
申请号：US13397398
申请日：2012-02-15
申请人： Francesco Viola , William F. Walker , Gregory V. Browne , Robert S. Magyar , Bjarne Hansen , Christopher G. Denny , Karen Platt
发明人： Francesco Viola , William F. Walker , Gregory V. Browne , Robert S. Magyar , Bjarne Hansen , Christopher G. Denny , Karen Platt
IPC分类号： G01N33/96 , C12M1/34 , C12Q1/56
CPC分类号： G01N33/86 , B01L3/5027 , B01L3/502761 , B01L3/527 , B01L2200/04 , B01L2200/0647 , B01L2300/02 , B01L2300/024 , B01L2300/027 , B01L2300/0627 , B01L2300/0654 , B01L2300/0681 , B01L2300/0816 , B01L2300/0829 , B01L2300/0861 , B01L2300/0864 , B01L2300/0867 , B01L2300/123 , B01L2300/14 , B01L2300/16 , B01L2300/1805 , B01L2400/0436 , B01L2400/0439 , B01L2400/0487 , B01L2400/049 , B01L2400/0666 , G01N29/024 , G01N29/222 , G01N35/00 , G01N2800/224
摘要： Provided are devices, systems and methods for evaluation of hemostasis. Also provided are sound focusing assemblies.
摘要翻译：提供了用于止血评估的装置，系统和方法。还提供声音聚焦组件。

3. 发明申请

US20110252352A1 Hemostatic Parameter Display 审中-公开
标题翻译：止血参数显示
公开(公告)号：US20110252352A1
公开(公告)日：2011-10-13
申请号：US13083360
申请日：2011-04-08
申请人： Francesco Viola , William F. Walker , Gregory V. Browne , Adam Looker , Bryan Roy , Bjarne Hansen
发明人： Francesco Viola , William F. Walker , Gregory V. Browne , Adam Looker , Bryan Roy , Bjarne Hansen
IPC分类号： G06F3/048
CPC分类号： G06Q50/24 , G06F19/00 , G16H15/00
摘要： A system for displaying a plurality of hemostatic indexes is disclosed. The system includes a communication receiver configured to receive the hemostatic indexes and a graphical user interface (GUI) connected to the communication receiver and configured to simultaneously display the hemostatic indexes. The hemostatic indexes are derived from a plurality of independent measurements, such as the mechanical measurements determined using the sonorheometry systems and processes.
摘要翻译：公开了一种用于显示多个止血指标的系统。该系统包括被配置为接收止血指数的通信接收器和连接到通信接收器并被配置为同时显示止血指数的图形用户界面（GUI）。止血指数来源于多个独立的测量结果，例如使用sonorheometry系统和过程确定的机械测量。

4. 发明授权

US10147152B2 Hemostatic parameter display 有权
公开(公告)号：US10147152B2
公开(公告)日：2018-12-04
申请号：US13083360
申请日：2011-04-08
申请人： Francesco Viola , William F. Walker , Gregory V. Browne , Adam Looker , Bryan Roy , Bjarne Hansen
发明人： Francesco Viola , William F. Walker , Gregory V. Browne , Adam Looker , Bryan Roy , Bjarne Hansen
IPC分类号： A61B5/157 , G06Q50/24 , G16H15/00
摘要： A system for displaying a plurality of hemostatic indexes is disclosed. The system includes a communication receiver configured to receive the hemostatic indexes and a graphical user interface (GUI) connected to the communication receiver and configured to simultaneously display the hemostatic indexes. The hemostatic indexes are derived from a plurality of independent measurements, such as the mechanical measurements determined using the sonorheometry systems and processes.

5. 发明授权

US09579120B2 Ultrasound for locating anatomy or probe guidance 有权
标题翻译：用于定位解剖或探针指导的超声
公开(公告)号：US09579120B2
公开(公告)日：2017-02-28
申请号：US13574738
申请日：2011-01-28
申请人： F. William Mauldin, Jr. , Francesco Viola , William F. Walker
发明人： F. William Mauldin, Jr. , Francesco Viola , William F. Walker
IPC分类号： A61B8/00 , A61B17/34 , A61B8/08
CPC分类号： A61B17/3403 , A61B8/0841 , A61B8/42 , A61B8/4254 , A61B8/4281 , A61B17/3401 , A61B46/10 , A61B2017/3413 , A61B2034/2048 , A61B2090/378
摘要： A hand-held apparatus can be used to assist in guiding a probe or locating a particular anatomical target in a subject. The apparatus can include an ultrasonic transducer located on or within a housing and configured to generate ultrasonic energy directed into tissue of a subject and configured to receive a portion of the ultrasonic energy reflected by a target located within the tissue. In an example, the apparatus can include a motion tracking circuit configured to provide information indicative of a motion of the hand-held apparatus to the processor circuit, and a display configured to present information about a location of the target with respect to a portion of the hand-held apparatus, the information about the location determined by the processor circuit using the obtained information indicative of the ultrasonic energy reflected by the target and the information indicative of the motion of the hand-held apparatus.
摘要翻译：可以使用手持式装置来帮助引导探针或将特定解剖学靶定位在受试者中。该装置可以包括位于壳体上或壳体内的超声波换能器，其被配置为产生被引导到对象的组织中的超声波能量，并被配置为接收由位于组织内的靶反射的超声能量的一部分。在一个示例中，该装置可以包括运动跟踪电路，其被配置为向处理器电路提供指示手持设备的运动的信息;以及显示器，被配置为呈现关于目标的位置相对于手持设备，使用所获得的指示由目标反射的超声能量的信息和由表示手持设备的运动的信息由处理器电路确定的位置的信息。

6. 发明授权

US08548759B2 Methods, apparatus, or systems for characterizing physical property in non-biomaterial or bio-material 有权
标题翻译：用于表征非生物材料或生物材料中物理性质的方法，装置或系统
公开(公告)号：US08548759B2
公开(公告)日：2013-10-01
申请号：US12940838
申请日：2010-11-05
申请人： William F. Walker , Francesco Viola , F. William Mauldin
发明人： William F. Walker , Francesco Viola , F. William Mauldin
IPC分类号： G01F17/00 , G06F11/30
CPC分类号： G01N29/07 , G01N2291/02466 , G01N2291/02827 , G01N2291/044 , G01N2291/102
摘要： Techniques (e.g., system, apparatus, method, machine-readable medium) can be configured for characterizing a rheological or other structural physical property of a sample of a substance. In an example, this can include acoustically bidirectionally deforming the portion of the sample over a deformation range about a neutral-deformation locus within the deformation range, measuring a deformation response of at least a portion of the sample to the insonification, and characterizing the physical property of the sample using the measured response of at least a portion of the sample to the insonification, even in the presence of a flowing substance.
摘要翻译：技术（例如，系统，装置，方法，机器可读介质）可以被配置为表征物质样品的流变学或其它结构物理性质。在一个示例中，这可以包括在变形范围内围绕中性 - 变形轨迹的变形范围使样本的部分声学双向变形，测量样品的至少一部分对于失真的变形响应，以及表征物理即使在存在流动物质的情况下，样品的至少一部分的测量响应也与样品的性质相关。

7. 发明申请

US20120296213A1 ULTRASOUND FOR LOCATING ANATOMY OR PROBE GUIDANCE 有权
标题翻译：用于定位解剖学或探针指导的超声波
公开(公告)号：US20120296213A1
公开(公告)日：2012-11-22
申请号：US13574738
申请日：2011-01-28
申请人： F. William Mauldin, JR. , Francesco Viola , William F. Walker
发明人： F. William Mauldin, JR. , Francesco Viola , William F. Walker
IPC分类号： A61B8/12 , A61B8/14 , A61B8/00
CPC分类号： A61B17/3403 , A61B8/0841 , A61B8/42 , A61B8/4254 , A61B8/4281 , A61B17/3401 , A61B46/10 , A61B2017/3413 , A61B2034/2048 , A61B2090/378
摘要： A hand-held apparatus can be used to assist in guiding a probe or locating a particular anatomical target in a subject. The apparatus can include an ultrasonic transducer located on or within a housing and configured to generate ultrasonic energy directed into tissue of a subject and configured to receive a portion of the ultrasonic energy reflected by a target located within the tissue. In an example, the apparatus can include a motion tracking circuit configured to provide information indicative of a motion of the hand-held apparatus to the processor circuit, and a display configured to present information about a location of the target with respect to a portion of the hand-held apparatus, the information about the location determined by the processor circuit using the obtained information indicative of the ultrasonic energy reflected by the target and the information indicative of the motion of the hand-held apparatus.
摘要翻译：可以使用手持式装置来帮助引导探针或将特定解剖学靶定位在受试者中。该装置可以包括位于壳体上或壳体内的超声波换能器，其被配置为产生被引导到对象的组织中的超声波能量，并被配置为接收由位于组织内的靶反射的超声能量的一部分。在一个示例中，该装置可以包括运动跟踪电路，其被配置为向处理器电路提供指示手持设备的运动的信息;以及显示器，被配置为呈现关于目标的位置相对于手持设备，使用所获得的指示由目标反射的超声能量的信息和由表示手持设备的运动的信息由处理器电路确定的位置的信息。

8. 发明授权

US08306293B2 Reduction of echo decorrelation facilitating motion estimation 有权
标题翻译：减少回波去相关促进运动估计
公开(公告)号：US08306293B2
公开(公告)日：2012-11-06
申请号：US12467216
申请日：2009-05-15
申请人： William F. Walker , Francesco Viola , William F. Mauldin, Jr.
发明人： William F. Walker , Francesco Viola , William F. Mauldin, Jr.
IPC分类号： G06K9/00 , G06K9/40
CPC分类号： G06K9/0051 , G01S7/52034 , G01S7/52042 , G01S7/52046 , G01S13/58 , G01S13/89 , G01S15/58 , G01S15/8977 , G01S15/8979 , G06K9/6247
摘要： Methods systems and computer readable media are provided for extracting information pertaining to at least one moving target. A set of signal data are inputted to a principal components processor, wherein the set of signal data comprise signal data corresponding to at least one waveform acquired from the at least one moving target. A complex representation of the set of signal data is formed and, using a principal components processor, at least one complex principal component of the complex representation is calculated. At least one of the calculated complex principal components is automatically selected and each of the at least one automatically selected complex principal component is applied to extract information about the at least one moving target. Methods systems and computer readable media are provided extracting information pertaining to at least one moving target. A set of signal data comprising signal data corresponding to at least one waveform acquired from the at least one moving target are inputted to a principal components processor. A complex representation of the set of signal data is formed, and at least one complex principal component of the complex representation is calculated. An estimated value of a physical characteristic of the at least one moving, target is then calculated, using a phase of at least one of the at least one complex principal components.
摘要翻译：提供方法系统和计算机可读介质用于提取与至少一个移动目标有关的信息。一组信号数据被输入到主要部件处理器，其中该组信号数据包括对应于从至少一个移动目标获得的至少一个波形的信号数据。形成该组信号数据的复数表示，并且使用主成分处理器来计算复数表示的至少一个复主体分量。自动选择所计算的复杂主成分中的至少一个，并且应用所述至少一个自动选择的复合主成分中的每一个以提取关于所述至少一个移动目标的信息。提供方法系统和计算机可读介质提取与至少一个移动目标有关的信息。包括与从至少一个移动目标获取的至少一个波形对应的信号数据的一组信号数据被输入到主要部件处理器。形成该组信号数据的复数表示，并计算该复数表示的至少一个复数主分量。然后使用所述至少一个复杂主成分中的至少一个的相位来计算所述至少一个移动目标的物理特性的估计值。

9. 发明授权

US07949498B2 Method, system and computer program product for registration of multi-dimensional datasets 有权
标题翻译：用于多维数据集注册的方法，系统和计算机程序产品
公开(公告)号：US07949498B2
公开(公告)日：2011-05-24
申请号：US11906614
申请日：2007-10-02
申请人： William F. Walker , Francesco Viola
发明人： William F. Walker , Francesco Viola
IPC分类号： G06F17/30
CPC分类号： G06T7/30
摘要： Methods, systems and computer program products for estimating changes in an object represented by first and second multidimensional datasets. The first dataset is a reference dataset and the second dataset is an altered dataset. Discrete data samples of the first dataset are processed to form a piecewise continuous representation thereof. An error function is computed for comparisons between discrete data samples in the second dataset and the piecewise continuous representation of the first dataset. An alteration of the second dataset relative to the first dataset that minimizes the error function is determined.
摘要翻译：用于估计由第一和第二多维数据集表示的对象的变化的方法，系统和计算机程序产品。第一个数据集是一个参考数据集，第二个数据集是一个更改的数据集。处理第一数据集的离散数据样本以形成其分段连续表示。计算第二数据集中的离散数据样本与第一个数据集的分段连续表示之间的比较的误差函数。确定第二数据集相对于使误差函数最小化的第一数据集的改变。

10. 发明申请

US20100142781A1 Systems and Method for Adaptive Beamforming for Image Reconstruction and/or Target/Source Localization 有权
标题翻译：用于图像重构和/或目标/源定位的自适应波束成形的系统和方法
公开(公告)号：US20100142781A1
公开(公告)日：2010-06-10
申请号：US11992368
申请日：2006-09-19
申请人： William F. Walker , Francesco Viola
发明人： William F. Walker , Francesco Viola
IPC分类号： G06K9/00
CPC分类号： G01S7/52046 , G01S7/52026 , G01S7/5205 , G01S7/52052 , G01S15/8977
摘要： Methods, systems and computer readable media for reconstruction of target locations and amplitudes from signals received from one or more real targets in a space are provided, wherein the signals are at least one of signals received from the near-field and broadband signals. The space is modeled as a region of interest, and an array manifold matrix is calculated from signals received from hypothetical targets in the region of interest. One or more signal vectors received from the one or more real targets are reshaped into a data vector. A hypothetical target configuration is identified that, when applied to a signal model comprising the array manifold matrix, matches the data vector, a reconstruction vector is calculated. The reconstruction vector is reshaped into a reconstructed representation of the real targets in the space, and at least one of outputting the reconstructed representation for viewing by a user, and storing the reconstructed representation for later use are performed.
摘要翻译：提供了用于从从空间中的一个或多个实际目标接收的信号重构目标位置和幅度的方法，系统和计算机可读介质，其中所述信号是从近场和宽带信号接收的信号中的至少一个。该空间被建模为感兴趣的区域，并且根据从感兴趣区域中的假想目标接收的信号计算阵列歧管矩阵。从一个或多个实际目标接收到的一个或多个信号向量重新形成数据向量。识别出假设的目标配置，当应用于包括阵列歧管矩阵的信号模型时，与数据矢量匹配，计算重构矢量。将重构矢量重新形成为空间中的真实目标的重建表示，并且执行输出用于观看的重建表示中的至少一个，并且存储用于稍后使用的重构表示。

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