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1. 发明授权

US08586086B2 Hydrogel capable of containing and conveying cells 有权
标题翻译：水凝胶能够容纳和输送细胞
公开(公告)号：US08586086B2
公开(公告)日：2013-11-19
申请号：US12994873
申请日：2009-05-29
申请人： Francesco Daniele , Carmen Giordano , Maurizio Masi , Giuseppe Perale , Filippo Rossi , Marta Tunesi
发明人： Francesco Daniele , Carmen Giordano , Maurizio Masi , Giuseppe Perale , Filippo Rossi , Marta Tunesi
IPC分类号： A61K9/14 , A61K35/12 , A61K35/30 , C12N5/00 , C12N5/079 , C12Q1/02 , A61P9/00 , A61P19/04 , A61P27/02 , A61P17/00 , A61P1/16 , A61P13/12 , A61P25/00 , A61P25/28 , A61P25/16
CPC分类号： A61K47/36 , A61K9/0024 , A61K9/0085 , A61K35/30 , A61K35/34 , A61K47/34
摘要： An interpenetrating biodegradable polymeric matrix hydrogel and the use thereof to support, encapsulate, convey and release several types of cells under conditions which allow the cells to be kept alive, grow and interconnect. The hydrogel may be used to prepare implants for integrally or partially regenerating, reconstructing and/or replacing damaged, dead or no longer functional tissues, in particular at the central nervous system or spinal marrow level. In such use, the biodegradability of the hydrogel allows a progressive release of the conveyed cells in order to promote their integration, even functional, with the surrounding tissue. The hydrogel may also be employed to support cells, for example, neural cells such as neuronal cells, on measuring devices, specifically realized for monitoring several parameters of cell activity, also during pharmacological and bio-mechanical tests.
摘要翻译：互穿生物可降解聚合物基质水凝胶及其在允许细胞保持活着，生长和互连的条件下支持，包封，传递和释放几种类型的细胞的用途。水凝胶可用于制备用于整体或部分再生，重建和/或替代损伤的，死亡的或不再功能的组织，特别是在中枢神经系统或脊髓水平的植入物。在这种用途中，水凝胶的生物降解性允许递送的细胞逐渐释放，以促进它们与周围组织的整合，甚至功能化。水凝胶还可用于在药物和生物机械测试期间，在测量装置上支持细胞，例如神经细胞，例如神经细胞，特别实现用于监测细胞活性的几个参数。

2. 发明申请

US20110189285A1 HYDROGEL CAPABLE OF CONTAINING AND CONVEYING CELLS 有权
标题翻译：包含和输送细胞的水凝胶
公开(公告)号：US20110189285A1
公开(公告)日：2011-08-04
申请号：US12994873
申请日：2009-05-29
申请人： Francesco Daniele , Carmen Giordano , Maurizio Masi , Giuseppe Perale , Filippo Rossi , Marta Tunesi
发明人： Francesco Daniele , Carmen Giordano , Maurizio Masi , Giuseppe Perale , Filippo Rossi , Marta Tunesi
IPC分类号： A61K9/14 , C12N5/00 , C12Q1/02 , A61K35/12 , A61K35/30 , C12N5/079 , A61P9/00 , A61P19/04 , A61P19/08 , A61P27/02 , A61P17/00 , A61P1/16 , A61P13/12 , A61P25/00 , A61P25/28 , A61P25/16
CPC分类号： A61K47/36 , A61K9/0024 , A61K9/0085 , A61K35/30 , A61K35/34 , A61K47/34
摘要： An interpenetrating biodegradable polymeric matrix hydrogel and the use thereof to support, encapsulate, convey and release several types of cells under conditions which allow the cells to be kept alive, grow and interconnect. The hydrogel may be used to prepare implants for integrally or partially regenerating, reconstructing and/or replacing damaged, dead or no longer functional tissues, in particular at the central nervous system or spinal marrow level. In such use, the biodegradability of the hydrogel allows a progressive release of the conveyed cells in order to promote their integration, even functional, with the surrounding tissue. The hydrogel may also be employed to support cells, for example, neural cells such as neuronal cells, on measuring devices, specifically realised for monitoring several parameters of cell activity, also during pharmacological and bio-mechanical tests.
摘要翻译：互穿生物可降解聚合物基质水凝胶及其在允许细胞保持活着，生长和互连的条件下支持，包封，传递和释放几种类型的细胞的用途。水凝胶可用于制备用于整体或部分再生，重建和/或替代损伤的，死亡的或不再功能的组织，特别是在中枢神经系统或脊髓水平的植入物。在这种用途中，水凝胶的生物降解性允许递送的细胞逐渐释放，以促进它们与周围组织的整合，甚至功能化。水凝胶还可用于在药物和生物机械测试期间，在测量装置上支持细胞，例如神经细胞，例如神经细胞，特别实现用于监测细胞活性的几个参数。

3. 发明授权

US07267064B2 Harness suitable for use on watercraft 失效
标题翻译：线束适用于船只
公开(公告)号：US07267064B2
公开(公告)日：2007-09-11
申请号：US10528045
申请日：2003-09-12
申请人： Giuseppe Perale , Alessandro Tedesco
发明人： Giuseppe Perale , Alessandro Tedesco
IPC分类号： B63H9/00 , A47L3/04
CPC分类号： B63H9/1007 , A62B35/0025 , B63B35/7993
摘要： A safety system of a harness, in particular of the trapezoidal type, is suitable for use on watercraft such as a yacht or windsurfer. A basic element (10) is coupled to the harness. A hook (15), suitable for being hooked by a cable, is coupled to the basic element (10). The basic element (10) has a first piece (31) connected to the harness and a second piece (30, 15) that can be disconnected from said first piece (31). The first piece (31) is coupled to the second piece (30, 15) by a coupling (32) that can be removed.
摘要翻译：特别是梯形类型的线束的安全系统适用于诸如游艇或风帆冲击器的船只上。基本元件（10）耦合到线束。适于被电缆钩住的钩（15）耦合到基本元件（10）。基本元件（10）具有连接到线束的第一件（31）和可以与所述第一件（31）断开的第二件（30,15）。第一部件（31）通过能够移除的联接器（32）联接到第二部件（30,15）。

4. 发明申请

US20060005754A1 Harness suitable for use on watercraft 失效
标题翻译：线束适用于船只
公开(公告)号：US20060005754A1
公开(公告)日：2006-01-12
申请号：US10528045
申请日：2003-09-12
申请人： Giuseppe Perale , Alessandroi Tedesco
发明人： Giuseppe Perale , Alessandroi Tedesco
IPC分类号： B63H9/00
CPC分类号： B63H9/1007 , A62B35/0025 , B63B35/7993
摘要： The present invention refers to a harness, in particular the trapezoidal type, suitable for use on watercraft such as yacht or windsurf. More specifically it refers to a safety system of the harness. In one embodiment thereof the harness suitable for use on watercraft comprises: a basic element (10) coupled to said harness; a hook (15), suitable for being hooked by a cable, coupled to said basic element (10); characterised in that said basic element (10) comprises a first piece (31) connected to said harness and of a second piece (30, 15), that can be disconnected from said first piece (31); said first piece (31) is coupled to said second piece (30, 15) by means of coupling means (32) that can be slipped out.
摘要翻译：本发明涉及一种适用于诸如游艇或风帆之类的船舶上的梯形特征的线束。更具体地说，它是指线束的安全系统。在其一个实施例中，适合用于船舶上的线束包括：联接到所述线束的基本元件（10）耦合到所述基本元件（10）的适于被电缆钩住的钩（15）; 其特征在于，所述基本元件（10）包括连接到所述线束的第一件（31）和可与所述第一件（31）断开的第二件（30,15）。所述第一件（31）借助于可以滑出的联接装置（32）联接到所述第二件（30,15）上。

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