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1. 发明申请

US20080186378A1 METHOD AND APPARATUS FOR GUIDING TOWARDS TARGETS DURING MOTION 审中-公开
标题翻译：在运动期间指导目标的方法和装置
公开(公告)号：US20080186378A1
公开(公告)日：2008-08-07
申请号：US11938888
申请日：2007-11-13
申请人： FEIMO SHEN , Dinesh Kumar , Jasjit S. Suri
发明人： FEIMO SHEN , Dinesh Kumar , Jasjit S. Suri
IPC分类号： H04N7/18
CPC分类号： A61B8/0833 , A61B8/0841 , A61B8/12 , A61B8/4254 , A61B8/483 , A61B8/5238 , G06T7/12 , G06T7/174 , G06T7/38 , G06T19/20 , G06T2207/10072 , G06T2207/10136 , G06T2207/30081 , G06T2219/2004 , G06T2219/2016
摘要： A method and apparatus are disclosed for three-dimensional (3D) imaging and continuously updating organ shape and internal points for guiding targets during motion. It is suitable for image-guided surgery or operations as the speed of this guidance is achieved in real-time.
摘要翻译：公开了用于三维（3D）成像并连续更新器官形状和内部点的方法和装置，用于在运动期间引导目标。适用于图像引导手术或手术操作，因为本指南的实时速度得以实时化。

2. 发明授权

US07832114B2 Tracker holder assembly 有权
标题翻译：跟踪器支架组件
公开(公告)号：US07832114B2
公开(公告)日：2010-11-16
申请号：US11850482
申请日：2007-09-05
申请人： Jasjit S. Suri , Dinesh Kumar , Animesh Khemka
发明人： Jasjit S. Suri , Dinesh Kumar , Animesh Khemka
IPC分类号： A61B8/00
CPC分类号： A61B8/12 , A61B8/4218 , A61B8/4245
摘要： Provided herein are devices and methods for mounting variously configured medical imaging probes to a tracker assembly for imaging applications. In one aspect, a tracker assembly provides multiple degrees of freedom for positioning a probe relative to a patient and/or maintaining a probe in a desired location for imaging purposes. The tracker generates location information that may be utilized as frame of reference information for acquired images. In another aspect a holding device allows for interfacing/holding differently configured probes in a common orientation to a predetermined frame of reference.
摘要翻译：本文提供了用于将各种配置的医学成像探针安装到用于成像应用的跟踪器组件的装置和方法。在一个方面，跟踪器组件提供多个自由度，用于将探针相对于患者定位和/或将探针保持在期望的位置以用于成像目的。跟踪器生成可用作所获取图像的参考信息的位置信息。在另一方面，保持装置允许以与预定参考系相同的方向将不同配置的探针连接/保持。

3. 发明申请

US20090048515A1 BIOPSY PLANNING SYSTEM 审中-公开
标题翻译：生物计划系统
公开(公告)号：US20090048515A1
公开(公告)日：2009-02-19
申请号：US11838518
申请日：2007-08-14
申请人： Jasjit S. Suri , Dinesh Kumar , Yujun Guo , Ramkrishnan Narayanan
发明人： Jasjit S. Suri , Dinesh Kumar , Yujun Guo , Ramkrishnan Narayanan
IPC分类号： A61B10/02 , A61B8/13
CPC分类号： A61B8/12 , A61B10/02 , A61B2017/00274 , A61B2018/00547 , A61B2090/367
摘要： Guided biopsy is a commonly used method to remove suspicious tissues from an internal organ for pathological tests so that malignancy can be established. Provided herein are systems and methods (i.e., utilities) that allow for automated application of one or more predefined biopsy target plans to an acquired medical image including without limitation, an ultrasound prostate image. Due to different shapes and sizes of prostates as well as orientation of prostate with respect to an ultrasound probe during image, acquisition a simple prostate model (e.g., ellipse) with a fixed plan may not be sufficient. Accordingly, it has been determined that a deformable shape model with integrated biopsy target locations/sites may be fit to a prostate image to provide improved automated biopsy targeting.
摘要翻译：引导活检是一种常用的方法，用于从内部器官中清除可疑组织进行病理检查，以确定恶性。本文提供了允许将一个或多个预定义的活检目标计划自动应用于所获取的医学图像的系统和方法（即实用程序），包括但不限于超声前列腺图像。由于在图像期间由于前列腺的不同形状和尺寸以及相对于超声探头的前列腺的取向，所以采集具有固定计划的简单前列腺模型（例如椭圆）可能不足够。因此，已经确定具有集成活检目标位置/位点的可变形形状模型可以适合于前列腺图像以提供改进的自动活检靶向。

4. 发明申请

US20100172559A1 SYSTEM AND METHOD FOR PROSTATE BIOPSY 审中-公开
标题翻译：用于预测生物的系统和方法
公开(公告)号：US20100172559A1
公开(公告)日：2010-07-08
申请号：US12615862
申请日：2009-11-10
申请人： Dinesh Kumar , Jasjit S. Suri
发明人： Dinesh Kumar , Jasjit S. Suri
IPC分类号： G06K9/00
CPC分类号： A61B10/0241 , A61B34/20 , A61B2090/3782 , G06T7/33 , G06T2207/10072 , G06T2207/10132 , G06T2207/30056 , G06T2207/30068 , G06T2207/30081 , G06T2207/30084
摘要： The invention presents tools to improve a 3-D image aided biopsy or treatment procedure for prostate gland by providing additional functionality and additional visual cues on an output image of the prostate, which may be generated substantially in real-time. The tools include i) the identification of various parts of prostate to classify as per regular classification in pathological reports, ii) Computing and displaying the insertion depth of needle with respect to a selected target point during the procedure, iii) Computing and displaying the distance from needle tip to prostate surface following a procedure and, iv) Calibration for misalignment of a 2-D imaging transducer when used under tracked motion for a procedure.
摘要翻译：本发明提供了通过在前列腺的输出图像上提供附加功能和附加视觉提示来实质上实时地产生用于改善前列腺的3-D图像辅助活组织检查或治疗过程的工具。这些工具包括：i）根据病理报告中的常规分类对前列腺各部分进行鉴定，ii）在手术过程中计算和显示相对于选定目标点的针插入深度，iii）计算和显示距离根据程序从针尖到前列腺表面，以及iv）当在跟踪运动下用于程序时，对2-D成像换能器的未对准进行校准。

5. 发明申请

US20100016710A1 PROSTATE TREATMENT APPARATUS 审中-公开
标题翻译：前台处理装置
公开(公告)号：US20100016710A1
公开(公告)日：2010-01-21
申请号：US12501943
申请日：2009-07-13
申请人： Dinesh Kumar , Jasjit S. Suri
发明人： Dinesh Kumar , Jasjit S. Suri
IPC分类号： A61B5/05
CPC分类号： A61B5/055 , A61B8/0833 , A61B8/0841 , A61B8/12 , A61B8/483 , A61B8/5223 , A61B18/02 , A61B18/08 , A61B2018/00547 , A61B2018/00577 , A61B2034/2063 , A61B2090/3784 , A61N5/1001 , A61N2005/1012 , A61N2005/1058
摘要： The presented invention aims to address these and/or additional issues by providing a tracked grid for brachytherapy applications that can adjust to changes in the prostate between original image acquisition. The grid is allowed to be moved around and even rotated under tracked conditions, such that it can be maneuvered to align with any target region. A virtual 3-D grid is displayed on a computer with respect to the actual anatomy of the patient. The tracked grid can be moved relative to the virtual 3-D grid, such that the brachytherapy, cryo therapy or any other type of image guided therapy may be performed in real 3-D or even 4-D, when motion compensation is embedded during the procedure.
摘要翻译：所提出的发明旨在通过提供一种用于近距离放射治疗应用的跟踪网格来解决这些和/或另外的问题，其可以适应原始图像采集之前的前列腺的变化。允许网格被移动并且甚至在跟踪条件下旋转，使得其可以被操纵以与任何目标区域对齐。相对于患者的实际解剖结构，在计算机上显示虚拟3-D网格。跟踪的网格可以相对于虚拟3-D网格移动，使得当在3-D或甚至4-D中嵌入运动补偿时，近距离放射治疗，低温治疗或任何其他类型的图像引导治疗可以被执行步骤。

6. 发明申请

US20080249403A1 TRACKER HOLDER ASSEMBLY 有权
标题翻译：履带架总成
公开(公告)号：US20080249403A1
公开(公告)日：2008-10-09
申请号：US11850482
申请日：2007-09-05
申请人： Jasjit S. Suri , Dinesh Kumar , Animesh Khemka
发明人： Jasjit S. Suri , Dinesh Kumar , Animesh Khemka
IPC分类号： A61B8/00
CPC分类号： A61B8/12 , A61B8/4218 , A61B8/4245
摘要： Provided herein are devices and methods for mounting variously configured medical imaging probes to a tracker assembly for imaging applications. In one aspect, a tracker assembly provides multiple degrees of freedom for positioning a probe relative to a patient and/or maintaining a probe in a desired location for imaging purposes. The tracker generates location information that may be utilized as frame of reference information for acquired images. In another aspect a holding device allows for interfacing/holding differently configured probes in a common orientation to a predetermined frame of reference.
摘要翻译：本文提供了用于将各种配置的医学成像探针安装到用于成像应用的跟踪器组件的装置和方法。在一个方面，跟踪器组件提供多个自由度，用于将探针相对于患者定位和/或将探针保持在期望的位置以用于成像目的。跟踪器生成可用作所获取图像的参考信息的位置信息。在另一方面，保持装置允许以与预定参考系相同的方向将不同配置的探针连接/保持。

7. 发明申请

US20080051648A1 MEDICAL IMAGE ENHANCEMENT SYSTEM 审中-公开
标题翻译：医学图像增强系统
公开(公告)号：US20080051648A1
公开(公告)日：2008-02-28
申请号：US11609743
申请日：2006-12-12
申请人： Jasjit S. Suri , Dinesh Kumar
发明人： Jasjit S. Suri , Dinesh Kumar
IPC分类号： A61B5/05
CPC分类号： A61B6/504 , A61B6/481 , A61B6/5235 , A61B6/5264 , G06T5/50 , G06T2207/10076 , G06T2207/10121 , G06T2207/20224 , G06T2207/30021
摘要： Provided herein is a medical imaging system that allows for real-time guidance of, for example, catheters for use in interventional procedures. In one arrangement, an imaging system is provided that generate a series of images or frames during a dye injection procedure. The system is operative to automatically detect frames that include dye (bolus frames) and frames that are free of dye (mask frames). The series of images may be registered together to provide a common reference frame and thereby account for motion. Sets of mask frames and bolus frames are averaged together, respectively, to improve signal to noise qualities. A differential image is generated utilizing the average mask and average bolus frames. Contrast of the differential image may be enhanced. The system allows for motion correction, noise reduction and/or enhancement of a differential image in real time.
摘要翻译：本文提供了一种医疗成像系统，其允许例如用于介入程序的导管的实时指导。在一种布置中，提供了在染料注射过程期间产生一系列图像或框架的成像系统。该系统可操作以自动检测包括染料（弹丸框）和无染料的框架（掩模框）的框架。一系列图像可以一起注册以提供公共参考帧，从而解释运动。分别将掩模帧和推注帧的组合平均化，以提高信噪比。使用平均掩模和平均推注帧产生差分图像。可以增强差分图像的对比度。该系统允许实时地进行差分图像的运动校正，降噪和/或增强。

8. 发明申请

US20080161687A1 REPEAT BIOPSY SYSTEM 审中-公开
标题翻译：重生生物系统
公开(公告)号：US20080161687A1
公开(公告)日：2008-07-03
申请号：US11750854
申请日：2007-05-18
申请人： Jasjit S. Suri , Dinesh Kumar , Yujun Guo
发明人： Jasjit S. Suri , Dinesh Kumar , Yujun Guo
IPC分类号： A61B8/00 , A61B10/02
CPC分类号： A61B8/5238 , A61B8/0833 , A61B10/0233 , A61B90/36 , A61B2017/00274 , A61B2018/00547 , A61B2090/364 , A61B2090/378
摘要： Provided herein are improved biopsy systems and methods (i.e., utilities), which among other benefits, assist physicians with the selection biopsy sites based on temporally distinct images. More generally, the utilities allow for registering medical images such that information associated with a medical image obtained at a first time may be mapped to a subsequent medical image obtained at a subsequent time. This may result in improved diagnosis, better planning, better treatment delivery and/or follow-up.
摘要翻译：本文提供了改进的活检系统和方法（即效用），其中除了其它益处之外，还可以基于时间上不同的图像帮助医生进行选择性活检部位。更通常地，实用程序允许登记医学图像，使得与第一次获得的医学图像相关联的信息可以被映射到在随后的时间获得的后续医学图像。这可能导致改善诊断，更好的规划，更好的治疗交付和/或后续行动。

9. 发明授权

US08571277B2 Image interpolation for medical imaging 有权
标题翻译：图像插值用于医学成像
公开(公告)号：US08571277B2
公开(公告)日：2013-10-29
申请号：US11874778
申请日：2007-10-18
申请人： Jasjit S. Suri , Dinesh Kumar
发明人： Jasjit S. Suri , Dinesh Kumar
IPC分类号： G06K9/00
CPC分类号： A61B8/12 , A61B8/4245 , A61B8/483 , A61B8/5238 , G06T3/4007
摘要： Presented are systems and methods that allow for interpolation of a 3-D volume from arbitrarily oriented 2-D medical images. The interpolation of 3-D volume from arbitrarily oriented 2-D images reduces or eliminates most constraints on image acquisition thereby allowing for, inter alia, freehand manipulation of an image acquisition device (e.g. an ultrasound transducer). Related utilities involve the use of prior information about a specific object of interest to interpolate a surface (e.g., 3-D surface) of the object from limited information obtained from very few 2-D images.
摘要翻译：提出了允许从任意取向的2-D医学图像插入3-D体积的系统和方法。任意取向的2-D图像的3-D体积的插值减少或消除了对图像采集的大部分约束，从而允许尤其是对图像采集装置（例如超声换能器）的手绘操纵。相关实用程序涉及使用关于特定感兴趣对象的先前信息来从非常少的2-D图像获得的有限信息内插对象的表面（例如，3-D表面）。

10. 发明授权

US08278913B2 Apparatus and method for position sensing 有权
标题翻译：位置检测装置及方法
公开(公告)号：US08278913B2
公开(公告)日：2012-10-02
申请号：US12466887
申请日：2009-05-15
申请人： Dinesh Kumar , Guangyao Xu , Jasjit S. Suri
发明人： Dinesh Kumar , Guangyao Xu , Jasjit S. Suri
IPC分类号： G01R7/14 , G01R7/30
CPC分类号： A61B17/3403 , A61B8/4245 , A61B10/0241 , A61B2017/3405 , A61B2017/3409 , A61B2017/3413 , A61B2090/061 , A61B2090/062 , A61B2090/067
摘要： An improved apparatus and method for position sensing of a medical tracker device are presented. The apparatus and method are designed to constrain, rotate, and track the position of a medical tool. To improve the position sensing of the tracker, a joint that provides two degrees of freedom may use a revolute gear pair together with a rotary sensor for angular motion sensing and a sliding/prismatic assembly together with a linear magnetic sensor for linear position sensing. Thus, the linear motion sensing and the angular motion sensing are decoupled.
摘要翻译：提出了一种用于医疗跟踪装置的位置检测的改进的装置和方法。设备和方法被设计成约束，旋转和跟踪医疗工具的位置。为了改善跟踪器的位置感测，提供两个自由度的接头可以与用于角运动检测的旋转传感器一起使用旋转齿轮对以及与用于线性位置感测的线性磁传感器的滑动/棱镜组件。因此，线性运动感测和角运动感测被解耦。

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