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1. 发明授权

US09287017B2 Differential phase-contrast imaging with increased dynamic range 有权
标题翻译：差分相位对比成像具有增加的动态范围
公开(公告)号：US09287017B2
公开(公告)日：2016-03-15
申请号：US13983063
申请日：2012-02-02
申请人： Thomas Koehler , Ewald Rössl
发明人： Thomas Koehler , Ewald Rössl
IPC分类号： G03H5/00 , G21K1/06 , A61B6/00 , A61B6/04
CPC分类号： G21K1/067 , A61B6/0407 , A61B6/4035 , A61B6/4078 , A61B6/4291 , A61B6/4441 , A61B6/484 , A61B6/508 , G21K1/06 , G21K2201/067 , G21K2207/005
摘要： In X-ray differential phase-contrast imaging. In order to enhance the information acquired by phase-contrast imaging, an analyzer grating (34) is provided with an absorption structure (48). The latter includes a first plurality (50) of first areas (52) with a first X-ray attenuation, and a second plurality (54) of second areas (56) with a second X-ray attenuation. The second X-ray attenuation is smaller than the first X-ray attenuation, and the first and second areas are arranged periodically in an alternating manner. A third plurality (58) of third areas (60) is provided with a third X-ray attenuation, which lies in a range from the second X-ray attenuation to the first X-ray attenuation, wherein every second of the first or second areas is replaced by one of the third areas.
摘要翻译：在X射线差分相位成像中。为了增强通过相位对比成像获取的信息，分析器光栅（34）设置有吸收结构（48）。后者包括具有第一X射线衰减的第一多个（50）第一区域（52）和具有第二X射线衰减的第二多个（54）第二区域（56）。第二X射线衰减小于第一X射线衰减，并且第一和第二区域以交替方式周期性地布置。第三多个（58）的第三区域（60）设置有第三X射线衰减，其位于从第二X射线衰减到第一X射线衰减的范围内，其中第一或第二地区被第三个地区之一所取代。

2. 发明授权

US10734128B2 Differential phase-contrast imaging with focussing deflection structure plates 有权
公开(公告)号：US10734128B2
公开(公告)日：2020-08-04
申请号：US13982781
申请日：2012-01-30
申请人： Ewald Rössl , Thomas Koehler
发明人： Ewald Rössl , Thomas Koehler
IPC分类号： G01N23/04 , G21K1/06
摘要： The present invention relates to X-ray differential phase-contrast imaging, in particular to a deflection device for X-ray differential phase-contrast imaging. In order to provide differential phase-contrast imaging with improved dose efficiency, a deflection device (28) for X-ray differential phase-contrast imaging is provided, comprising a deflection structure (41) with a first plurality (44) of first areas (46), and a second plurality (48) of second areas (50). The first areas are provided to change the phase and/or amplitude of an X-ray radiation; and wherein the second areas are X-ray transparent. The first and second areas are arranged periodically such that, in the cross section, the deflection structure is provided with a profile arranged such that the second areas are provided in form of groove-like recesses (54) formed between first areas provided as projections (56). The adjacent projections form respective side surfaces (58) partly enclosing the respective recess arranged in between. The side surfaces of each recess have a varying distance (60) across the depth (62) of the recess.

3. 发明申请

US20130308751A1 DIFFERENTIAL PHASE-CONTRAST IMAGING WITH INCREASED DYNAMIC RANGE 有权
标题翻译：具有增加的动态范围的差分相位对比成像
公开(公告)号：US20130308751A1
公开(公告)日：2013-11-21
申请号：US13983063
申请日：2012-02-02
申请人： Thomas Koehler , Ewald Rössl
发明人： Thomas Koehler , Ewald Rössl
IPC分类号： G21K1/06
CPC分类号： G21K1/067 , A61B6/0407 , A61B6/4035 , A61B6/4078 , A61B6/4291 , A61B6/4441 , A61B6/484 , A61B6/508 , G21K1/06 , G21K2201/067 , G21K2207/005
摘要： The present invention relates to X-ray differential phase-contrast imaging. In order to enhance the information acquired by phase-contrast imaging, an analyzer grating (34) for X-ray differential phase-contrast imaging is provided with an absorption structure (48). The latter comprises a first plurality (50) of first areas (52) with a first X-ray attenuation, and a second plurality (54) of second areas (56) with a second X-ray attenuation. The second X-ray attenuation is smaller than the first X-ray attenuation, and the first and second areas are arranged periodically in an alternating manner. A third plurality (58) of third areas (60) is provided with a third X-ray attenuation, which lies in a range from the second X-ray attenuation to the first X-ray attenuation, wherein every second of the first or second areas is replaced by one of the third areas.
摘要翻译：本发明涉及X射线差分相位成像。为了增强通过相位对比成像获得的信息，用于X射线差分相位对比成像的分析器光栅（34）具有吸收结构（48）。后者包括具有第一X射线衰减的第一多个（50）第一区域（52）和具有第二X射线衰减的第二多个（54）第二区域（56）。第二X射线衰减小于第一X射线衰减，并且第一和第二区域以交替方式周期性地布置。第三多个（58）的第三区域（60）设置有第三X射线衰减，其位于从第二X射线衰减到第一X射线衰减的范围内，其中第一或第二地区被第三个地区之一所取代。

4. 发明申请

US20130315373A1 DIFFERENTIAL PHASE-CONTRAST IMAGING WITH FOCUSSING DEFLECTION STRUCTURE PLATES 审中-公开
标题翻译：具有聚焦偏转结构板的差分相位成像
公开(公告)号：US20130315373A1
公开(公告)日：2013-11-28
申请号：US13982781
申请日：2012-01-30
申请人： Ewald Rössl , Thomas Koehler
发明人： Ewald Rössl , Thomas Koehler
IPC分类号： G21K1/06 , G01N23/04
摘要： The present invention relates to X-ray differential phase-contrast imaging, in particular to a deflection device for X-ray differential phase-contrast imaging. In order to provide differential phase-contrast imaging with improved dose efficiency, a deflection device (28) for X-ray differential phase-contrast imaging is provided, comprising a deflection structure (41) with a first plurality (44) of first areas (46), and a second plurality (48) of second areas (50). The first areas are provided to change the phase and/or amplitude of an X-ray radiation; and wherein the second areas are X-ray transparent. The first and second areas are arranged periodically such that, in the cross section, the deflection structure is provided with a profile arranged such that the second areas are provided in form of groove-like recesses (54) formed between first areas provided as projections (56). The adjacent projections form respective side surfaces (58) partly enclosing the respective recess arranged in between. The side surfaces of each recess have a varying distance (60) across the depth (62) of the recess.
摘要翻译：本发明涉及X射线差分相位对比成像，特别涉及用于X射线差分相位对比成像的偏转装置。为了提供具有改进的剂量效率的差分相位对比成像，提供了一种用于X射线差分相位对比成像的偏转装置（28），包括具有第一多个第一区域（44）的偏转结构（41） 46）和第二多个（48）第二区域（50）。提供第一区域以改变X射线辐射的相位和/或幅度; 并且其中所述第二区域是X射线透明的。第一和第二区域周期性地布置，使得在横截面中，偏转结构设置有轮廓，轮廓布置成使得第二区域以形成在作为突起的第一区域之间形成的凹槽状凹部（54） 56）。相邻的突起形成部分地围绕设置在其间的相应凹部的相应侧表面（58）。每个凹部的侧表面具有穿过凹部的深度（62）的变化的距离（60）。

5. 发明授权

US09750465B2 Scanning system for differential phase contrast imaging 有权
公开(公告)号：US09750465B2
公开(公告)日：2017-09-05
申请号：US13514312
申请日：2010-12-08
申请人： Klaus Juergen Engel , Dieter Geller , Gereon Vogtmeier , Thomas Koehler
发明人： Klaus Juergen Engel , Dieter Geller , Gereon Vogtmeier , Thomas Koehler
IPC分类号： A61B6/00 , A61B6/03
CPC分类号： A61B6/00 , A61B6/032 , A61B6/4291 , A61B6/484 , A61B6/488 , A61B6/5241
摘要： The invention relates to the field of X-ray differential phase contrast imaging. For scanning large objects and for an improved contrast to noise ratio, an X-ray device (10) for imaging an object (18) is provided. The X-ray device (10) comprises an X-ray emitter arrangement (12) and an X-ray detector arrangement (14), wherein the X-ray emitter arrangement (14) is adapted to emit an X-ray beam (16) through the object (18) onto the X-ray detector arrangement (14). The X-ray beam (16) is at least partial spatial coherent and fan-shaped. The X-ray detector arrangement (14) comprises a phase grating (50) and an absorber grating (52). The X-ray detector arrangement (14) comprises an area detector (54) for detecting X-rays, wherein the X-ray device is adapted to generate image data from the detected X-rays and to extract phase information from the X-ray image data, the phase information relating to a phase shift of X-rays caused by the object (18). The object (18) has a region of interest (32) which is larger than a detection area of the X-ray detector (18) and the X-ray device (10) is adapted to generate image data of the region of interest (32) by moving the object (18) and the X-ray detector arrangement (14) relative to each other.

6. 发明授权

US09105369B2 Differential phase-contrast imaging with improved sampling 有权
标题翻译：差分相位对比成像与改进采样
公开(公告)号：US09105369B2
公开(公告)日：2015-08-11
申请号：US13819764
申请日：2011-08-26
申请人： Thomas Koehler
发明人： Thomas Koehler
IPC分类号： A61B6/00 , G21K1/06 , A61B6/03 , G21K1/02 , G01N23/04
CPC分类号： G21K1/067 , A61B6/032 , A61B6/4035 , A61B6/4291 , A61B6/484 , G01N23/04 , G21K1/02 , G21K2207/005
摘要： The present invention relates to differential phase-contrast imaging of an object. For increasing spatial resolution of an X-ray imaging system (2) the size of a detector pixel element (8) may be considered a limiting factor. Accordingly, it may be beneficial to increase the resolution of an apparatus (38) for phase-contrast imaging without further reducing the area of an individual pixel element (8). Accordingly, an apparatus (38) for phase-contrast imaging with improved sampling is provided, comprising an X-ray source (4), a first grating element G1 (24), a second grating element G2 (26) and an X-ray detector element (6) comprising a plurality of detector pixel elements (8), each detector pixel element (8) having a pixel area A. An object to be imagined (14) is arrangeable between the X-ray source (4) and the X-ray detector element (6). The first grating element G1 (24) as well as the second grating element G2 (26) are arrangeable between the X-ray source (4) and the X-ray detector element (6). The X-ray source (4), the first grating element G1 (24), the second grating element G2 (26) and the X-ray detector (6) are operatively coupled for acquisition of a phase-contrast image of the object (14). At least one of the first grating element G1 (24) and the second grating element G2 (26) comprise a first area A1 having a first grating pitch p1 and a second area A2 having a second grating pitch p2 different from the first grating pitch.
摘要翻译：本发明涉及物体的差分相位对比成像。为了增加X射线成像系统的空间分辨率（2），检测器像素元件（8）的尺寸可以被认为是限制因素。因此，增加用于相位对比成像的装置（38）的分辨率可能是有益的，而不进一步减小单个像素元件（8）的面积。因此，提供了一种用于具有改进采样的相位对比成像的装置（38），包括X射线源（4），第一光栅元件G1（24），第二光栅元件G2（26）和X射线检测器元件（6）包括多个检测器像素元件（8），每个检测器像素元件（8）具有像素区域A.要想象的物体（14）可布置在X射线源（4）和 X射线检测元件（6）。第一光栅元件G1（24）以及第二光栅元件G2（26）可布置在X射线源（X）和X射线探测元件（6）之间。 X射线源（4），第一光栅元件G1（24），第二光栅元件G2（26）和X射线检测器（6）可操作地耦合以获取对象的相位差图像 14）。第一光栅元件G1（24）和第二光栅元件G2（26）中的至少一个包括具有第一光栅间距p1的第一区域A1和具有与第一光栅间距不同的第二光栅间距p2的第二区域A2。

7. 发明授权

US09084528B2 Phase contrast imaging 有权
标题翻译：相位成像
公开(公告)号：US09084528B2
公开(公告)日：2015-07-21
申请号：US13514682
申请日：2010-12-03
申请人： Dieter Geller , Klaus Juergen Engel , Gereon Vogtmeier , Thomas Koehler , Ewald Roessl
发明人： Dieter Geller , Klaus Juergen Engel , Gereon Vogtmeier , Thomas Koehler , Ewald Roessl
IPC分类号： G01N23/04 , A61B6/00
CPC分类号： A61B6/00 , A61B6/4291 , A61B6/4441 , A61B6/484
摘要： X-ray devices for Phase Contrast Imaging (PCI) are often built up with the help of gratings. For large field-of-views (FOV), production cost and complexity of these gratings could increase significantly as they need to have a focused geometry. Instead of a pure PCI with a large FOV, this invention suggests to combine a traditional absorption X-ray-imaging system with large-FOV with an insertable low-cost PCI system with small-FOV, The invention supports the user to direct the PCI system with reduced FOV to a region that he regards as most interesting for performing a PCI scan thus eliminating X-ray dose exposure for scanning regions not interesting for a radiologist. The PCI scan may be generated on the basis of local tomography.
摘要翻译：用于相位对比成像（PCI）的X射线装置通常在光栅的帮助下构建。对于大视野（FOV）来说，这些光栅的生产成本和复杂性可能会因为需要聚焦几何而显着增加。本发明不是采用具有大FOV的纯PCI，而是将传统的吸收X射线成像系统与大型FOV结合，并具有小FOV的可插入低成本PCI系统。本发明支持用户指导PCI 系统将FOV降低到他认为对于执行PCI扫描最有趣的区域，从而消除了用于放射科医生不感兴趣的扫描区域的X射线剂量曝光。可以基于局部断层摄影产生PCI扫描。

8. 发明授权

US09066649B2 Apparatus for phase-contrast imaging comprising a displaceable X-ray detector element and method 有权
标题翻译：包括可移位的X射线检测器元件和方法的用于相位对比成像的装置
公开(公告)号：US09066649B2
公开(公告)日：2015-06-30
申请号：US13514383
申请日：2010-12-03
申请人： Ewald Roessl , Klaus Juergen Engel , Gereon Vogtmeier , Dieter Geller , Gerhard Martens , Sebastian Siegmund Schusser , Thomas Koehler
发明人： Ewald Roessl , Klaus Juergen Engel , Gereon Vogtmeier , Dieter Geller , Gerhard Martens , Sebastian Siegmund Schusser , Thomas Koehler
IPC分类号： A61B6/00 , A61B6/03
CPC分类号： A61B6/00 , A61B6/032 , A61B6/4021 , A61B6/4092 , A61B6/4291 , A61B6/484
摘要： An X-ray image acquisition apparatus employing phase-contrast imaging with enlarged field of view includes an X-ray source, an X-ray detector element having a detector size, a beam splitter grating and an analyzer grating. An object is arrangeable between the X-ray source and detector. The beam splitter grating and the analyzer grating are arrangeable between the X-ray source and detector. The X-ray source, the beam splitter grating, the analyzer grating and the X-ray detector are operatively coupled such that a phase-contrast image of the object is obtainable. The apparatus is configure to acquire a phase-contrast image having a field of view larger than the detector size. The X-ray detector element is displaceable where, by the displacement of the X-ray detector, a phase-contrast image of the enlarged field of view is obtainable.
摘要翻译：采用具有放大视场的相位对比成像的X射线图像获取装置包括X射线源，具有检测器尺寸的X射线检测器元件，分束器光栅和分析器光栅。 X射线源和检测器之间可以配置一个物体。分束器光栅和分析器光栅可以在X射线源和检测器之间布置。 X射线源，分束器光栅，分析器光栅和X射线检测器可操作地耦合，使得可以获得物体的相差图像。该装置被配置为获取具有大于检测器尺寸的视场的相位对比度图像。 X射线检测器元件可移动，其中通过X射线检测器的位移可以获得放大视场的相位对比图像。

9. 发明授权

US08966221B2 Translating translation requests having associated priorities 有权
标题翻译：翻译具有相关优先级的翻译请求
公开(公告)号：US08966221B2
公开(公告)日：2015-02-24
申请号：US13165013
申请日：2011-06-21
申请人： Ute Gaertner , Thomas Koehler
发明人： Ute Gaertner , Thomas Koehler
IPC分类号： G06F12/00 , G06F13/00 , G06F12/10 , G06F12/08
CPC分类号： G06F12/1027 , G06F12/0855
摘要： A lookup operation is performed in a translation look aside buffer based on a first translation request as current translation request, wherein a respective absolute address is returned to a corresponding requestor for the first translation request as translation result in case of a hit. A translation engine is activated to perform at least one translation table fetch in case the current translation request does not hit an entry in the translation look aside buffer, wherein the translation engine is idle waiting for the at least one translation table fetch to return data, reporting the idle state of the translation engine as lookup under miss condition and accepting a currently pending translation request as second translation request, wherein a lookup under miss sequence is performed in the translation look aside buffer based on said second translation request.
摘要翻译：在基于第一翻译请求的翻译旁边缓冲器中执行查找操作作为当前翻译请求，其中相应的绝对地址在命中情况下作为翻译结果返回给第一翻译请求的对应请求者。翻译引擎被激活以执行至少一个转换表提取，以防当前转换请求没有到达翻译旁边缓冲器中的条目，其中翻译引擎空闲等待至少一个转换表提取返回数据，将所述翻译引擎的空闲状态报告为在未命中条件下的查找，并接受当前待处理的转换请求作为第二转换请求，其中在所述翻译旁边缓冲器中基于所述第二翻译请求执行在未命中序列下的查找。

10. 发明授权

US08861674B2 Computed tomography apparatus 有权
标题翻译：计算机断层摄影仪
公开(公告)号：US08861674B2
公开(公告)日：2014-10-14
申请号：US13509840
申请日：2010-12-10
申请人： Thomas Koehler , Roland Proksa , Ewald Roessl
发明人： Thomas Koehler , Roland Proksa , Ewald Roessl
IPC分类号： A61B6/00 , A61B6/03 , G01N23/04 , G06T11/00
CPC分类号： A61B6/032 , A61B6/469 , A61B6/542 , G01N23/046 , G01N2223/419 , G06T11/005 , Y10S378/901
摘要： The invention relates to a computed tomography apparatus for imaging an object. The computed tomography apparatus comprises a radiation source (2) for generating modulated radiation (4) traversing the object and a detector (6) for generating detection values depending on the radiation (4) after having traversed the object, while the radiation source (2) and the object are moved relative to each other. A weight providing unit (14) provides modulation weights for weighting the detection values depending on the modulation of the radiation (4) and a reconstruction unit (15) reconstructs an image of the object, wherein the detection values are weighted based on the provided modulation weights and an image of the object is reconstructed from the weighted detection values. This can allow to optimize the dose application to the object by modulating the radiation accordingly, wherein the reconstructed images still have a high quality.
摘要翻译：本发明涉及一种用于对物体成像的计算机断层摄影装置。计算机断层摄影装置包括用于产生经过物体的调制辐射（4）的辐射源（2）和用于在穿过物体之后产生取决于辐射（4）的检测值的检测器（6），而辐射源）并且对象相对于彼此移动。权重提供单元（14）根据辐射（4）的调制提供用于对检测值进行加权的调制权重，并且重建单元（15）重建对象的图像，其中基于所提供的调制对所述检测值进行加权从加权检测值重建对象的权重和图像。这可以通过相应地调节辐射来优化对物体的剂量应用，其中重建的图像仍然具有高质量。

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