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1. 发明申请

US20060052359A1 7-Amino alkylidenyl-heterocyclic quinolones and naphthyridones 有权
标题翻译： 7-氨基亚烷基 - 杂环喹诺酮和萘啶酮
公开(公告)号：US20060052359A1
公开(公告)日：2006-03-09
申请号：US11084987
申请日：2005-03-21
申请人： Eugene Grant , Mark Macielag , Steven Paget , Michele Weidner-Wells , Xiaoqing Xu , Xiaodong Xu
发明人： Eugene Grant , Mark Macielag , Steven Paget , Michele Weidner-Wells , Xiaoqing Xu , Xiaodong Xu
IPC分类号： A61K31/519 , A61K31/4745 , A61K31/4709 , C07D487/02 , C07D403/02
CPC分类号： C07D215/56 , C07D401/04 , C07D471/04
摘要： The present invention relates to compounds having a structure according to Formula I wherein n, m, z, R, R2, R3, R4, R5, R6, A, E, X, Y, a and b are as defined above; or an optical isomer, diastereomer or enantiomer thereof; a pharmaceutically acceptable salt, hydrate, or prodrug thereof.
摘要翻译：本发明涉及具有式I结构的化合物

2. 发明申请

US20050101588A1 7-Amino alkylidenyl-heterocyclic quinolones and naphthyridones 有权
标题翻译： 7-氨基亚烷基 - 杂环喹诺酮和萘啶酮
公开(公告)号：US20050101588A1
公开(公告)日：2005-05-12
申请号：US10937238
申请日：2004-09-09
申请人： Eugene Grant , Mark Macielag , Xiaoqing Xu , Steven Paget , Michele Weidner-Wells
发明人： Eugene Grant , Mark Macielag , Xiaoqing Xu , Steven Paget , Michele Weidner-Wells
IPC分类号： A61K31/435 , A61K31/47 , A61K31/4709 , A61K31/4745 , A61K31/519 , A61P31/04 , C07D401/04 , C07D403/04 , C07D471/02 , C07D471/04 , C07D487/04 , C07D498/06 , C07D43/02
CPC分类号： C07D403/04 , C07D401/04 , C07D471/04
摘要： The present invention relates to compounds having a structure according to Formula I wherein n, m, z, R, R2, R3, R4, R5, R6, A, E, X, Y, a and b are as defined above; or an optical isomer, diastereomer or enantiomer thereof; a pharmaceutically acceptable salt, hydrate, or prodrug thereof.
摘要翻译：本发明涉及具有式I结构的化合物，其中n，m，z，R，R 2，R 3，R 4， R 5，R 6，A，E，X，Y，a和b如上所定义; 或其光学异构体，非对映异构体或对映异构体; 其药学上可接受的盐，水合物或前药。

3. 发明授权

US08133137B2 Pitching machine having optimal adjustability 有权
标题翻译：投球机具有最佳的可调性
公开(公告)号：US08133137B2
公开(公告)日：2012-03-13
申请号：US12386019
申请日：2009-04-14
申请人： Eugene Grant , William R. Woessner , Ian Fettes
发明人： Eugene Grant , William R. Woessner , Ian Fettes
IPC分类号： A63B69/00 , F41B15/00 , F41B4/00
CPC分类号： A63B69/406 , A63B2069/0008 , A63B2069/402 , A63B2102/02 , A63B2102/14 , A63B2102/18 , A63B2102/182 , A63B2243/0025 , A63B2243/0037 , A63B2243/0095
摘要： A pitching machine configured for adjustment by a user, and including a pitching head, a first macro-adjustment device and a first micro-adjustment device. The pitching head is situated atop a stand. The pitching head includes a first wheel spaced apart from an opposing surface and a first motor for driving the first wheel. The first macro-adjustment device is coupled to the pitching head and includes a first locking assembly that, when loosened, allows manual rotation of the pitching head about a first pivot axis. The first micro-adjustment device is coupled to the pitching head, and includes a first adjusting element that, when repositioned, incrementally rotates the pitching head about the first pivot axis. The first micro-adjustment device configured for operation by a single hand of a user, and the first macro-adjustment device retaining the pitching head in a secure position during adjustment of the first micro-adjustment device.
摘要翻译：一种俯仰机器，其构造为用于由用户调节，并包括俯仰头，第一宏观调节装置和第一微调装置。俯仰头位于支架顶部。俯仰头包括与相对表面间隔开的第一轮和用于驱动第一轮的第一马达。第一宏观调节装置联接到俯仰头并且包括第一锁定组件，当松开时允许俯仰头围绕第一枢转轴线手动旋转。第一微型调节装置联接到俯仰头部，并且包括第一调节元件，当重新定位时，第一调节元件逐渐地使俯仰头围绕第一枢转轴线旋转。第一微型调节装置，其被配置为通过用户的单手进行操作，以及第一宏观调节装置，在调整第一微调装置期间将俯仰头保持在安全位置。

4. 发明授权

US06793594B1 Sports practice net 失效
标题翻译：体育练习网
公开(公告)号：US06793594B1
公开(公告)日：2004-09-21
申请号：US10397271
申请日：2003-03-27
申请人： Eugene Grant
发明人： Eugene Grant
IPC分类号： A63B6300
CPC分类号： A63B63/00 , A63B69/3623 , A63B71/022 , A63B2208/12
摘要： A free standing net system incorporates a full sized floor for easy ball collection and a built in training target secured to a rear wall of a netted enclosure which is functional for multi-sport use. The netting of the enclosure is 1000 denier polyester, treated for long wear and UV resistance. The floor is constructed of high density nylon with a water-resistant polyurethane coating. The sleeves located at the peripheral edges of the netting are engaged by two shock-corded poles to provide a cantilevered frame portion projecting above and towards the sports enthusiast. The cantilevered frame portion is specifically designed to trap wedge shots during golf practice. Angled side wings of the netted enclosure allow free swinging motion with any golf club to provide a wide angle of capture during golf practice swings.
摘要翻译：独立的网络系统结合了一个全尺寸的地板，便于球的收集，并且内置的训练目标固定在网箱的后壁上，可用于多运动用途。外壳网为1000旦涤纶，经久耐磨和耐紫外线处理。地板由耐高温聚氨酯涂层的高密度尼龙构成。位于网的周边边缘的袖子由两个防震绳杆接合，以提供向运动爱好者上方和朝向运动爱好者伸出的悬臂框架部分。悬臂框架部分专门设计用于在高尔夫球练习期间捕捉楔形射击。网状外壳的倾斜侧翼允许任何高尔夫球杆自由摆动，以在高尔夫练习摆动期间提供广泛的捕获角度。

5. 发明授权

US08074633B2 Ball projecting machine 有权
标题翻译：球投机
公开(公告)号：US08074633B2
公开(公告)日：2011-12-13
申请号：US12386020
申请日：2009-04-14
申请人： Eugene Grant , William R. Woessner , Ian Fettes
发明人： Eugene Grant , William R. Woessner , Ian Fettes
IPC分类号： A63B69/00
CPC分类号： A63B69/406 , A63B2069/0008 , A63B2069/402 , A63B2102/02 , A63B2102/14 , A63B2102/18 , A63B2102/182 , A63B2243/0025 , A63B2243/0037 , A63B2243/0095
摘要： A ball projecting machine having a C-shaped arm that provides the ability to adjust the length or elevation of pitched balls. The C-shaped arm connects a ball projecting head to a stand, with the ball projecting head affixed to one end of the C-shaped arm, and the C-shaped arm is slidably engaged through a frame atop the stand to allow rotation of the ball projecting head about a horizontal axis. A center of gravity of the ball projecting head in combination with the C-shaped arm facilitates stability of the ball projecting machine when the C-shaped arm is slid up or down. A locking device, when loosened, allows the C-shaped arm to slide up or down through the frame.
摘要翻译：一种具有C形臂的球形投影机，其提供调节球形球的长度或高度的能力。 C形臂将球形突起头连接到支架上，其中球形突出头固定在C形臂的一端，并且C形臂通过支架顶部的框架可滑动地接合，以允许旋转球投射头围绕水平轴。与C形臂组合的球投射头的重心有助于当C形臂上下滑动时投球机的稳定性。锁定装置松开时，允许C形臂通过框架上下滑动。

6. 外观设计

USD566801S1 Batting tee 有权
标题翻译：打三通
公开(公告)号：USD566801S1
公开(公告)日：2008-04-15
申请号：US29286165
申请日：2007-04-26
申请人： Eugene Grant
设计人： Eugene Grant

7. 发明申请

US20060190177A1 Nanocircuitry for sensing, recording and outputting data 失效
标题翻译：用于感测，记录和输出数据的纳米电路
公开(公告)号：US20060190177A1
公开(公告)日：2006-08-24
申请号：US11060874
申请日：2005-02-18
申请人： Charles Grant , Eugene Grant
发明人： Charles Grant , Eugene Grant
IPC分类号： G01V7/00
CPC分类号： G01V9/00 , Y10S977/943 , Y10S977/95 , Y10S977/953
摘要： The device implements nanotechnology by embedding nanocircuits with sensors to surfaces such as walls, wall coverings, clothing, windows, window coverings, flooring, roofs, roadways and telephone poles. Using a plurality of nanocircuits in a multitude of locations, events can be continuously detected and recorded without intrusion, and reconstructed at a later time.
摘要翻译：该设备通过将具有传感器的纳米电路嵌入诸如墙壁，墙壁，衣服，窗户，窗帘，地板，屋顶，道路和电话杆的表面来实现纳米技术。在多个位置使用多个纳米电路，可以不间断地连续检测和记录事件，并在以后重建。

8. 发明申请

US20050159442A1 Protein tyrosine phosphatase 1B (PTP-1B) inhibitors and methods of using the same 审中-公开
标题翻译：蛋白酪氨酸磷酸酶1B（PTP-1B）抑制剂及其使用方法
公开(公告)号：US20050159442A1
公开(公告)日：2005-07-21
申请号：US10975813
申请日：2004-10-28
申请人： Danlin Xu , Francis Farrell , Eugene Grant , Frank Brown
发明人： Danlin Xu , Francis Farrell , Eugene Grant , Frank Brown
IPC分类号： A61K31/445 , A61K31/4745 , A61K31/60 , C07D471/04
CPC分类号： C07D471/04 , A61K31/445 , A61K31/4745 , A61K31/60
摘要： A novel class of compounds has been identified that inhibit PTP-1B through a newly discovered binding interaction. Methods of treating, preventing or delaying the onset of, conditions mediated by PTP-1B are also provided. The compounds are capable of interacting with the primary binding pocket of PTP-1B via a hydrogen bond acceptor and have an aqueous phase free energy more positive than about −1200 kJ/mol. Representative compounds in the class are those of Formula I: or an optical isomer, enantiomer, diastereomer, racemate or racemic mixture thereof, ester, prodrug or metabolite form, or a pharmaceutically acceptable salt thereof, wherein R1, R2 and/or R3 are independently hydrogen atoms or alkyl groups and G1 and G2 are aryl, heteroaryl, alkyl, arylalkanyl, arylalkenyl, arylalkynyl, heteroarylalkanyl, heteroarylalkenyl, or heteroarylalkynyl moieties.
摘要翻译：已经鉴定出新类化合物通过新发现的结合相互作用抑制PTP-1B。还提供了治疗，预防或延缓由PTP-1B介导的病症发作的方法。该化合物能够通过氢键受体与PTP-1B的主要结合口相互作用，并且具有比约-1200kJ / mol更正的水相游离能。该类中的代表性化合物是式I的那些：或其旋光异构体，对映体，非对映异构体，外消旋体或外消旋混合物，酯，前药或代谢物形式或其药学上可接受的盐，其中R 1， R 2和/或R 3独立地是氢原子或烷基，G 1和G 2是芳基，杂芳基，烷基，芳基烷基，芳基烯基，芳基炔基，杂芳基烷基，杂芳基烯基或杂芳基炔基部分。

9. 发明申请

US20090260612A1 Ball projecting machine 有权
标题翻译：球投机
公开(公告)号：US20090260612A1
公开(公告)日：2009-10-22
申请号：US12386020
申请日：2009-04-14
申请人： Eugene Grant , William R. Woessner , Ian Fettes
发明人： Eugene Grant , William R. Woessner , Ian Fettes
IPC分类号： A63B69/40
CPC分类号： A63B69/406 , A63B2069/0008 , A63B2069/402 , A63B2102/02 , A63B2102/14 , A63B2102/18 , A63B2102/182 , A63B2243/0025 , A63B2243/0037 , A63B2243/0095
摘要： A ball projecting machine having a C-shaped arm that provides the ability to adjust the length or elevation of pitched balls. The C-shaped arm connects a ball projecting head to a stand, with the ball projecting head affixed to one end of the C-shaped arm, and the C-shaped arm is slidably engaged through a frame atop the stand to allow rotation of the ball projecting head about a horizontal axis. A center of gravity of the ball projecting head in combination with the C-shaped arm facilitates stability of the ball projecting machine when the C-shaped arm is slid up or down. A locking device, when loosened, allows the C-shaped arm to slide up or down through the frame.
摘要翻译：一种具有C形臂的球形投影机，其提供调节球形球的长度或高度的能力。 C形臂将球形突起头连接到支架上，其中球形突出头固定在C形臂的一端，并且C形臂通过支架顶部的框架可滑动地接合，以允许旋转球投射头围绕水平轴。与C形臂组合的球投射头的重心有助于当C形臂上下滑动时投球机的稳定性。锁定装置松开时，允许C形臂通过框架上下滑动。

10. 发明申请

US20090260611A1 Pitching machine having optimal adjustability 有权
标题翻译：投球机具有最佳的可调性
公开(公告)号：US20090260611A1
公开(公告)日：2009-10-22
申请号：US12386019
申请日：2009-04-14
申请人： Eugene Grant , William R. Woessner , Ian Fettes
发明人： Eugene Grant , William R. Woessner , Ian Fettes
IPC分类号： A63B69/40
CPC分类号： A63B69/406 , A63B2069/0008 , A63B2069/402 , A63B2102/02 , A63B2102/14 , A63B2102/18 , A63B2102/182 , A63B2243/0025 , A63B2243/0037 , A63B2243/0095
摘要： A pitching machine configured for adjustment by a user, and including a pitching head, a first macro-adjustment device and a first micro-adjustment device. The pitching head is situated atop a stand. The pitching head includes a first wheel spaced apart from an opposing surface and a first motor for driving the first wheel. The first macro-adjustment device is coupled to the pitching head and includes a first locking assembly that, when loosened, allows manual rotation of the pitching head about a first pivot axis. The first micro-adjustment device is coupled to the pitching head, and includes a first adjusting element that, when repositioned, incrementally rotates the pitching head about the first pivot axis. The first micro-adjustment device configured for operation by a single hand of a user, and the first macro-adjustment device retaining the pitching head in a secure position during adjustment of the first micro-adjustment device.
摘要翻译：一种俯仰机器，其构造为用于由用户调节，并包括俯仰头，第一宏观调节装置和第一微调装置。俯仰头位于支架顶部。俯仰头包括与相对表面间隔开的第一轮和用于驱动第一轮的第一马达。第一宏观调节装置联接到俯仰头并且包括第一锁定组件，当松开时允许俯仰头围绕第一枢转轴线手动旋转。第一微型调节装置联接到俯仰头，并且包括第一调节元件，当重新定位时，第一调节元件逐渐地使俯仰头围绕第一枢转轴线旋转。第一微型调节装置，其被配置为通过用户的单手进行操作，以及第一宏观调节装置，在调整第一微调装置期间将俯仰头保持在安全位置。

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