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1. 发明授权

US4625170A NMR imaging method and apparatus 失效
标题翻译： NMR成像方法和装置
公开(公告)号：US4625170A
公开(公告)日：1986-11-25
申请号：US635154
申请日：1984-07-27
申请人： Etsuji Yamamoto , Shigeru Matsui , Masuo Kuroda , Hideki Kohno
发明人： Etsuji Yamamoto , Shigeru Matsui , Masuo Kuroda , Hideki Kohno
IPC分类号： G01R33/20 , A61B5/055 , A61B10/00 , G01R33/48 , G01R33/565
CPC分类号： G01R33/56518
摘要： An NMR imaging method and apparatus of the type in which a 180-degree RF pulse is applied to generate a spin echo after the selective excitation of a spin by a 90-degree RF pulse. A dummy gradient field, which has the same direction and intensity as those of a gradient field to be applied when the spin echo is observed, is applied between said 90-degree RF pulse and said 180-degree RF pulse so that the instant of starting the application of the gradient field for signal observation is advanced to the extent corresponding to said dummy gradient field.
摘要翻译：一种NMR成像方法和装置，其中施加180度RF脉冲以在旋转选择性激发90度RF脉冲之后产生自旋回波。在所述90度RF脉冲和所述180度RF脉冲之间，施加与观察到自旋回波时要施加的梯度场相同的方向和强度的虚拟梯度场，使得起始时刻将用于信号观察的梯度场的应用提前到对应于所述虚拟梯度场的程度。

2. 发明授权

US4777443A Inspection apparatus based on nuclear magnetic resonance 失效
标题翻译：基于核磁共振的检测装置
公开(公告)号：US4777443A
公开(公告)日：1988-10-11
申请号：US119489
申请日：1987-11-12
申请人： Masao Yabusaki , Etsuji Yamamoto , Takashi Onodera , Yukiko Ogura , Hideaki Nakane , Shigeru Matsui , Hideki Kohno
发明人： Masao Yabusaki , Etsuji Yamamoto , Takashi Onodera , Yukiko Ogura , Hideaki Nakane , Shigeru Matsui , Hideki Kohno
IPC分类号： G01R33/035 , G01R33/36 , G01R33/20
CPC分类号： G01R33/326 , G01R33/0358
摘要： Disclosed in a nuclear magnetic resonance (NMR) based inspection apparatus using an SQUID flux meter for detecting a small NMR signal, in which a receiving coil for receiving the NMR signal from an object is connected to a mixer, which mixes a reference high-frequency signal with the NMR signal so that the NMR signal is reduced to a low-frequency signal having a differential component of frequencies of both signals, and the low-frequency signal is applied to the input coil of the SQUID flux meter so that it is converted into a voltage signal. The mixer circuit includes Schottky diodes operative at a liquid helium temperature or Josephson junctions, and the portions of apparatus from the reception coil up to the SQUID flux meter are operated in a superconductive state at a liquid helium temperature.
摘要翻译：在使用SQUID通量计检测小型NMR信号的基于核磁共振（NMR）的检查装置中公开了一种用于从物体接收NMR信号的接收线圈连接到混频器，该混频器将参考高频用NMR信号进行信号，使得NMR信号被减少到具有两个信号的频率的差分分量的低频信号，并且低频信号被施加到SQUID通量计的输入线圈，使得其被转换变成电压信号。混频器电路包括以液氦温度或约瑟夫逊结操作的肖特基二极管，并且从接收线圈到SQUID通量计的装置部分在液氦温度下处于超导状态。

3. 发明授权

US4683433A Imaging method and apparatus using nuclear magnetic resonance 失效
标题翻译：使用核磁共振的成像方法和装置
公开(公告)号：US4683433A
公开(公告)日：1987-07-28
申请号：US636995
申请日：1984-08-02
申请人： Etsuji Yamamoto , Hideki Kohno , Masao Kuroda , Shigeru Matsui , Hidemi Shiono
发明人： Etsuji Yamamoto , Hideki Kohno , Masao Kuroda , Shigeru Matsui , Hidemi Shiono
IPC分类号： G01R33/20 , A61B5/055 , A61B10/00 , G01R33/48 , G01R33/54 , G01R33/56
CPC分类号： G01R33/482 , G01R33/56
摘要： An NMR imaging apparatus and method for detecting a nuclear spin resonance signal from an object, which is placed in a magnetic field, to produce images of the object. At an instant when the spins come into phase after the signal detection by a first spin excitation, RF magnetic field pulses are applied for rotating the direction of the spin to that opposite to the initial state. After that, the spin excitation and the signal direction of second time are conducted to measure the data which are different in the effect of the relaxation time from the first measurements. By repeating these sequences, it is possible to produce a plurality of images such as an intensity image or a relaxation time enhanced image.
摘要翻译：一种用于检测放置在磁场中的物体的核自旋共振信号的NMR成像设备和方法，以产生物体的图像。在通过第一自旋激发在信号检测之后自旋进入相位的瞬间，施加RF磁场脉冲以将旋转方向旋转到与初始状态相反的方向。之后，进行自旋激励和第二次的信号方向，以测量与第一次测量相比，松弛时间的影响不同的数据。通过重复这些序列，可以产生多个图像，例如强度图像或弛豫时间增强图像。

4. 发明授权

US4716369A High speed imaging method with three-dimensional NMR 失效
标题翻译：高速成像方法采用三维NMR
公开(公告)号：US4716369A
公开(公告)日：1987-12-29
申请号：US746663
申请日：1985-06-20
申请人： Kensuke Sekihara , Shigeru Matsui , Hideki Kohno , Etsuji Yamamoto , Hidemi Shiono
发明人： Kensuke Sekihara , Shigeru Matsui , Hideki Kohno , Etsuji Yamamoto , Hidemi Shiono
IPC分类号： G01R33/485 , G01R33/561 , G01R33/20
CPC分类号： G01R33/485 , G01R33/5615 , G01R33/5616
摘要： The present invention is an imaging method using three-dimensional NMR to which an echo-planar method is applied. After excitation of nuclear spins, the gradient magnetic field Gx for phase-encoding is applied and there is repeated a sequence of measuring and obtaining an echo train of spin-echoes with a constant gradient magnetic field Gx and a periodically-inverted gradient magnetic field Gy, as varying the amount of encoding, so as to obtain the three-dimensional imaging by the Fourier-conversion. Moreover, after the selective excitation of spins within an X-Y surface, a 180.degree. radio frequency pulse is applied. As varying the time difference .tau..sub..epsilon. between the interval from the excitation until the application of the 180.degree. radio frequency pulse and the interval from the application thereof until a peak of a first echo of an echo train, three-dimensional imaging is carried out with a chemical shift axis as one axis by repeating the sequence and accomplishing Fourier-conversion with .tau..sub..epsilon. as a numerical variable.
摘要翻译：本发明是使用采用回波平面法的三维NMR的成像方法。在激励核自旋之后，施加用于相位编码的梯度磁场Gx，并且重复测量并获得具有恒定梯度磁场Gx和周期性反转梯度磁场Gy的自旋回波回波序列的序列，因为改变编码量，从而通过傅里叶变换获得三维成像。此外，在X-Y表面中的自旋选择性激发之后，施加180°射频脉冲。随着从激励到施加180°射频脉冲的间隔与从应用到应用的间隔直到回波列的第一回波的峰值之间的时间差τεε改变，三维成像是化学位移轴作为一个轴，通过重复该序列，并以tauε作为数值变量进行傅里叶变换。

5. 发明授权

US4672318A Method of measuring the static magnetic field distribution in an NMR inspection system 失效
标题翻译：在NMR检查系统中测量静态磁场分布的方法
公开(公告)号：US4672318A
公开(公告)日：1987-06-09
申请号：US696909
申请日：1985-01-31
申请人： Kensuke Sekihara , Etsuji Yamamoto , Shigeru Matsui , Hideki Kohno
发明人： Kensuke Sekihara , Etsuji Yamamoto , Shigeru Matsui , Hideki Kohno
IPC分类号： G01R33/20 , A61B5/055 , A61B10/00 , G01R33/24 , G01R33/38 , G01R33/387
CPC分类号： G01R33/24
摘要： A method of measuring a static magnetic field distribution in a nuclear magnetic resonance (NMR) inspection system which comprises magnetic field generator for producing a static magnetic field, inclination or gradient magnetic fields and a high-frequency magnetic field, a signal detector for sensing nuclear magnetic resonance signals from an inspection sample, a computer for processing output signals from the signal detector and an output device for providing a computational result of the computer, wherein a time interval t.sub.1 from the center of a 90.degree.-pulse high-frequency magnetic field to the center of a 180.degree.-pulse high-frequency magnetic field is made different by a time difference t.sub.0 from a time interval t.sub.2 from the center of the 180.degree.-pulse high-frequency magnetic field to a peak of a spin echo, so that static magnetic field distribution is calculated based on the computer output which corresponds to the difference of the two time intervals.
摘要翻译：一种在核磁共振（NMR）检查系统中测量静磁场分布的方法，其包括用于产生静磁场，倾斜或梯度磁场和高频磁场的磁场发生器，用于感测核的信号检测器来自检查样本的磁共振信号，用于处理来自信号检测器的输出信号的计算机和用于提供计算机的计算结果的输出装置，其中从90°脉冲高频磁场的中心起的时间间隔t1 从180°脉冲高频磁场的中心到从180°脉冲高频磁场的中心到自旋回波的峰值的时间间隔t2由时间差t0变化到180°脉冲高频磁场的中心，因此基于对应于两个时间间隔的差的计算机输出来计算静态磁场分布。

6. 发明授权

US4791369A Method of measuring magnetic field error of an NMR imaging apparatus and of correcting distortion caused by the error 失效
标题翻译：测量NMR成像设备的磁场误差并校正由误差引起的失真的方法
公开(公告)号：US4791369A
公开(公告)日：1988-12-13
申请号：US72035
申请日：1987-07-10
申请人： Etsuji Yamamoto , Hideki Kohno
发明人： Etsuji Yamamoto , Hideki Kohno
IPC分类号： A61B5/055 , A61B10/00 , G01R33/24 , G01R33/48 , G01R33/565 , G01R33/20
CPC分类号： G01R33/24 , G01R33/56563 , G01R33/56518
摘要： A method of finding error distribution in the static magnetic field and distribution of deviations from straight lines in the gradient magnetic fields of an NMR imaging apparatus which employs the applied spin-warp method. A phantom whose shape has been known is measured in the read-out gradient magnetic fields having different polarities to obtain two spin density distribution images. The two images are then compared with the shape of said phantom to measure the distortion distributions of the images. Error in the static magnetic field and deviations of the gradient magnetic fields from the straight lines are analyzed from the distortion distributions. From the thus obtained error distribution, furthermore, distortion induced in imaging the object is estimated, and the distortion contained in the image that is reconstructed from the spin density of the object by the spin-warp method is corrected using the thus estimated value.
摘要翻译：在使用所采用的旋转翘曲方法的NMR成像装置的梯度磁场中找到静态磁场中的误差分布和偏离直线偏差的方法。在具有不同极性的读出梯度磁场中测量其形状已知的体模，以获得两个自旋密度分布图像。然后将两个图像与所述体模的形状进行比较，以测量图像的失真分布。从失真分布中分析静态磁场的误差和梯度磁场与直线的偏差。此外，根据这样得到的误差分布，估计在物体成像时引起的失真，并且使用这样估计的值来校正通过旋转扭曲方法从物体的自旋密度重构的图像中包含的失真。

7. 发明授权

US4472683A Imaging apparatus using nuclear magnetic resonance 失效
标题翻译：使用核磁共振成像设备
公开(公告)号：US4472683A
公开(公告)日：1984-09-18
申请号：US420303
申请日：1982-09-20
申请人： Kensuke Sekihara , Etsuji Yamamoto , Hideki Kohno , Shinji Yamamoto
发明人： Kensuke Sekihara , Etsuji Yamamoto , Hideki Kohno , Shinji Yamamoto
IPC分类号： A61B10/00 , A61B5/055 , G01R33/48 , G01R33/54 , G01R33/08
CPC分类号： G01R33/4833
摘要： An imaging apparatus using nuclear magnetic resonance is disclosed in which both an image corresponding to the projection of a nuclear spin distribution in a to-be-inspected object on a two-dimensional plane and a display mark indicating a desired measuring position are displayed on a display face of a display device such as a CRT display, the display mark is freely moved on the display face to be set at a desired position on the display face, and magnetic field generating means for generating a static magnetic field, linear gradient field, or radio frequency magnetic field is controlled on the basis of the desired position of the display mark to obtain an image of that cross section of the object which is located at a position indicated by the display mark.
摘要翻译：公开了一种使用核磁共振的成像装置，其中在二维平面上的被检查物体中的核自旋分布的投影和指示期望的测量位置的显示标记的图像都显示在 CRT显示器等显示装置的显示面，在显示面上自由移动显示标记，将其设定在显示面上的期望位置，产生静磁场，线性梯度场，或者基于显示标记的期望位置来控制射频磁场，以获得位于由显示标记指示的位置处的对象的该横截面的图像。

8. 发明授权

US5109198A Nuclear magnetic resonance imaging apparatus 失效
标题翻译：核磁共振成像装置
公开(公告)号：US5109198A
公开(公告)日：1992-04-28
申请号：US469916
申请日：1990-01-24
申请人： Yoshiki Murakami , Etsuji Yamamoto , Masao Yabusaki , Hideki Kohno , Munetaka Tsuda , Toshihiro Ishizuka
发明人： Yoshiki Murakami , Etsuji Yamamoto , Masao Yabusaki , Hideki Kohno , Munetaka Tsuda , Toshihiro Ishizuka
IPC分类号： G01R33/34
CPC分类号： G01R33/34046
摘要： In a nuclear magnetic resonance imaging apparatus including a first probe circuit for detecting magnetic flux in a first direction and a second probe circuit for detecting magnetic flux in a direction perpendicular to the first direction, the arm angle of conductor arms to form the first probe circuit and the arm angle of conductor arms to form the second probe circuit are different from each other.
摘要翻译：在包括用于检测第一方向的磁通的第一探针电路和用于检测与第一方向垂直的方向上的磁通的第二探针电路的核磁共振成像装置中，形成第一探针电路的导体臂的臂角并且形成第二探针电路的导体臂的臂角彼此不同。

9. 发明授权

US4875013A High-frequency coil for nuclear magnetic imaging 失效
标题翻译：高频线圈用于核磁成像
公开(公告)号：US4875013A
公开(公告)日：1989-10-17
申请号：US162982
申请日：1988-03-02
申请人： Yoshiki Murakami , Etsuji Yamamoto , Masao Yabusaki , Hideki Kohno
发明人： Yoshiki Murakami , Etsuji Yamamoto , Masao Yabusaki , Hideki Kohno
IPC分类号： G01R33/343
CPC分类号： G01R33/343
摘要： A high-frequency coil of the type of slot resonator in which outer conductors that have wing portions at both ends thereof and that are divided, are formed on the cylindrical surface, and ring-like inner conductors are formed on the inside of the wing portions. The wing portions have a width different from the width of the inner conductors. The self resonance frequency of the coil is adjusted by adjusting the width which is smaller than the other width. Further, the neighboring tips of the wing portions are opposed to each other via an air gap. The self resonance frequency is also adjusted depending upon the position of the dielectric plate inserted in the gap.
摘要翻译：在圆筒形表面上形成有槽谐振器类型的高频线圈，其中在其两端具有翼部并被分割的外导体，并且在翼部的内侧形成有环形的内导体。翼部的宽度不同于内导体的宽度。通过调节小于另一个宽度的宽度来调节线圈的自谐振频率。此外，翼部的相邻端部经由气隙彼此相对。自谐振频率也根据插入间隙中的电介质板的位置来调节。

10. 发明授权

US4739265A NMR imaging method 失效
标题翻译： NMR成像方法
公开(公告)号：US4739265A
公开(公告)日：1988-04-19
申请号：US846151
申请日：1986-03-31
申请人： Etsuji Yamamoto , Kensuke Sekihara , Hidemi Shiono , Hideki Kohno
发明人： Etsuji Yamamoto , Kensuke Sekihara , Hidemi Shiono , Hideki Kohno
IPC分类号： G01R33/485 , G01R33/565 , G01R33/20
CPC分类号： G01R33/565 , G01R33/485 , G01R33/56527
摘要： A method for providing spin density distribution images of an object, discriminated with respect to plural chemical shifts. This method is performed by repeating a measurement sequence in a spin warp imaging method, of the spin data plural times, with a time difference .DELTA..tau. between a time interval .tau..sub.1 from spin excitation to a 180.degree. RF pulse and a time interval .tau..sub.2 from the 180.degree. RF pulse to a peak of a spin echo, altering .DELTA..tau. in the ways corresponding the number of chemical shifts to be discriminated from one another, subjecting the respective spin data to two-dimensional Fourier transform to provide plural sets of spin data for respective coordinates in a spatial domain, and solving simultaneous equations of the sets of spin data to provide spin densities corresponding to the respective chemical shifts.
摘要翻译：一种用于提供对象的自旋密度分布图像的方法，其被鉴别为多个化学位移。该方法通过在旋转数据成像方法中重复自旋数据多次的测量序列，其中从自旋激发到180°RF脉冲的时间间隔τ1与时间间隔τ2之间的时间差DELTAτ 从180°RF脉冲到自旋回波的峰值，以相应于要彼此区分的化学位移数的方式改变DELTA tau，对各自旋转数据进行二维傅里叶变换以提供多组旋转用于空间域中的各个坐标的数据，以及求解自旋数据组的联立方程以提供对应于各个化学位移的自旋密度。

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