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1. 发明申请

US20130110137A1 Surface Treated Polymeric Synthetic Hernia Mesh Prosthesis, Surface Treated Sutures and Staples and Methods of Manufacturing the Same 审中-公开
标题翻译：表面处理聚合物合成疝网假体，表面处理缝线和钉子及其制造方法
公开(公告)号：US20130110137A1
公开(公告)日：2013-05-02
申请号：US13632197
申请日：2012-10-01
申请人： Enrico Nicolo , Linda Cahalan , Greg Johnson , Mark Gartner , Patrick Cahalan , Brian J Fill , Ali HUSSAIN , Jeffrey W. Speakman
发明人： Enrico Nicolo , Linda Cahalan , Greg Johnson , Mark Gartner , Patrick Cahalan , Brian J Fill , Ali HUSSAIN , Jeffrey W. Speakman
IPC分类号： A61L27/24 , A61L27/22
CPC分类号： A61L27/24 , A61L27/227 , A61L31/048 , A61L31/10 , A61L33/0029 , A61L2400/18 , A61M1/1698 , C08L83/04 , C08L23/12
摘要： A variety of polymeric synthetic hernia mesh prosthesis with surface treatment on at least one tissue-facing surface to control tissue adhesion are disclosed including heparin surface treatment which provides heparin present in an amount to yield heparin bioactivity of at least one of i) an ATIII binding of at least 2 pmol/cm2, and ii) a thrombin deactivation of at least 0.2 IU/cm2; an acrylic surface treatment for coupling thereto of a heparin surface treatment, a collagen surface treatment or both; and an amino-functional polysiloxane surface treatment for coupling thereto of a heparin surface treatment. The synthetic hernia mesh may be formed of monofilament or multifilament polypropylene or polyester, and may be formed as a multi-layer prosthesis with an outer layer formed of a polymeric synthetic hernia mesh with surface treatment to control tissue adhesion coupled to one or more polymeric synthetic hernia meshes without such surface treatments.
摘要翻译：公开了在至少一个面向组织的表面上进行表面处理以控制组织粘附的各种聚合合成疝网假体，其包括肝素表面处理，其提供一定量的肝素以产生以下至少一种的肝素生物活性：i）ATIII结合至少2pmol / cm 2，和ii）至少0.2IU / cm 2的凝血酶失活; 用于与肝素表面处理，胶原表面处理或两者结合的丙烯酸表面处理; 和用于与肝素表面处理偶联的氨基官能聚硅氧烷表面处理。合成疝网可以由单丝或多丝聚丙烯或聚酯形成，并且可以形成为具有由聚合物合成疝网形成的外层的多层假体，其具有表面处理以控制与一种或多种聚合物合成没有这种表面处理的疝气网眼。

2. 发明授权

US6117148A Intraluminal anastomotic device 有权
标题翻译：腔内吻合装置
公开(公告)号：US6117148A
公开(公告)日：2000-09-12
申请号：US173867
申请日：1998-10-16
申请人： Biagio Ravo , Enrico Nicolo
发明人： Biagio Ravo , Enrico Nicolo
IPC分类号： A61B17/115 , A61B17/04
CPC分类号： A61B17/115 , A61B17/1155
摘要： An intestinal intraluminal reconstruction and resection device includes a mechanism for intussusception of the bowel, a bowel anastomosis mechanism and a mechanism for severing the resected bowel. The surgical device allows the user to carry out intraluminally an anastomosis first, prior to resection of the intestine or any hollow viscus, therefore not exposing the dirty intraluminal content to the clean abdominal or thoracic cavities. The above is achieved by first intussuscepting the hollow viscus, then anastomosis and finally intraluminal resection.
摘要翻译：肠腔内重建和切除装置包括肠套叠机构，肠吻合机制和切除肠道的机制。手术装置允许使用者在切除肠或任何中空粘液之前首先进行内镜吻合，因此不会将脏的腔内内容物暴露于清洁的腹部或胸腔。以上是通过首先套管中空粘液，然后吻合并最终进行腔内切除来实现的。

3. 发明申请

US20120078274A1 METHOD AND APPARATUS OF TENSION FREE INGUINAL HERNIA REPAIR RECONSTRUCTING PHYSIOLOGY USING INGUINAL HERNIA PROSTHETIC HAVING LATERAL NON-ENCIRCLING CORD LOCATING STRUCTURE 审中-公开
标题翻译：方法和装置免费INNUINAL HERNIA修复重建生理学使用INGUINE HERNIA具有横向非包裹线定位结构的假体
公开(公告)号：US20120078274A1
公开(公告)日：2012-03-29
申请号：US13078338
申请日：2011-04-01
申请人： Enrico Nicolo
发明人： Enrico Nicolo
IPC分类号： A61B17/03
CPC分类号： A61F2/0063
摘要： An inguinal hernia prosthesis includes a cord locating structure that provides cord protecting functions. The cord locating structure, which may be a semi-circular or other shaped recess positioned along a longitudinal peripheral edge of the prosthesis, is designed to only surround a portion of the cord, e.g. less than 180 or preferably 120 degrees, with the remaining cord circumference being positioned by the element against appropriate muscle tissue. The cord locating structure may be referenced as a non-encircling lateral cord locating structure. The prosthetic: provides tension free repair; minimizes cord damage through tissue ingrowth/strangulation effects, inadvertent suturing through the cord structure, and abrasion with the prosthetic; and minimizes size of prosthetic used in the repair; and is configured to reconstitutes the pre-hernia muscle physiology.
摘要翻译：腹股沟疝假体包括提供电线保护功能的电线定位结构。绳索定位结构可以是沿着假体的纵向周边边缘定位的半圆形或其它形状的凹槽，其被设计成仅围绕绳索的一部分，例如，小于180度或优选120度，其余绳索周围由该元件抵靠适当的肌肉组织定位。绳索定位结构可以被称为非环绕侧向绳索定位结构。假肢：提供无张力修复; 通过组织向内生长/窒息效应，通过绳索结构的无意缝合以及与假体的磨损来最小化绳索损伤; 并使修复中使用的假体的尺寸最小化; 并且被配置为重建疝前肌肉生理学。

4. 发明授权

US5937445A One-piece surgical mask and cap 失效
标题翻译：一体式手术口罩和帽子
公开(公告)号：US5937445A
公开(公告)日：1999-08-17
申请号：US969782
申请日：1997-11-13
申请人： Biagio Ravo , Enrico Nicolo
发明人： Biagio Ravo , Enrico Nicolo
IPC分类号： A41D13/11 , A42B1/04
CPC分类号： A42B1/046 , A41D13/1153 , Y10S2/901
摘要： The one-piece surgical mask and cap includes a substantially planar blank with an eye opening formed therethrough. Straps are attached to the side edges of the blank for connecting the one-piece surgical mask and cap to the user. The upper portion of the blank above the eye opening forms the cap portion, and the lower portion of the blank below the eye opening forms the mask portion. Elastic bands may be provided surrounding the eye opening to further secure the one-piece surgical mask and cap of the present invention to the user.
摘要翻译：一体式手术掩模和帽包括基本上平面的坯料，其中形成有眼孔。带子连接到坯件的侧边缘，用于将一体式手术口罩和帽子连接到使用者。眼睛开口上方的毛坯的上部形成盖部分，并且在眼睛开口下方的坯件的下部形成掩模部分。可以围绕眼睛开口设置弹性带，以进一步将本发明的一体式外科口罩和帽固定到使用者身上。

5. 发明授权

US06981979B2 Surgical anastomotic devices 失效
公开(公告)号：US06981979B2
公开(公告)日：2006-01-03
申请号：US10320749
申请日：2002-12-16
申请人： Enrico Nicolo
发明人： Enrico Nicolo
IPC分类号： A61B17/04
CPC分类号： A61B17/0643 , A61B17/1114 , A61B17/1152 , A61B2017/1107 , A61B2017/1135 , A61B2017/1139
摘要： Specifically, the anastomosis device of the present invention provides an anastomosis ring; such as but not limited to a ring of staples, in the form of an oval or ellipse. One specific embodiment of the present invention is a side to end anastomotic stapler with a row of staples formed in an elliptical pattern. Another embodiment of the present invention is a pair of anastomotic compression rings formed in an ellipse. A further embodiment of the invention is compression disc, rather than open ring structure.

6. 发明授权

US06652595B1 Method of repairing inguinal hernias 失效
标题翻译：修复腹股沟疝的方法
公开(公告)号：US06652595B1
公开(公告)日：2003-11-25
申请号：US09488724
申请日：1998-01-09
申请人： Enrico Nicolo
发明人： Enrico Nicolo
IPC分类号： A61F202
CPC分类号： A61F2/0063
摘要： A universal, surgical prosthesis for hernia repair is provided in the form of a foldable sheet. The prosthesis includes a barrier layer formed of a material adapted to prevent biological adherence thereto, such as polytetrafluoroethylene, and a second surface layer formed of a material adapted to promote biological tissue adherence thereto, such as polypropylene. The second surface may be formed of a series of spaced projections. The prosthesis is adapted to be manipulated into an operative position to exhibit an appropriate exterior when in the operative position. In this manner, the universal, surgical prosthesis can be utilized for a wide range of surgical procedures.
摘要翻译：以可折叠片的形式提供用于疝修补的通用的外科假体。假体包括由适于防止生物粘附的材料（例如聚四氟乙烯）形成的阻挡层，以及由适于促进生物组织粘附的材料（例如聚丙烯）形成的第二表面层。第二表面可以由一系列间隔的突起形成。假体适于在处于操作位置时被操纵到操作位置以显示适当的外部。以这种方式，通用的外科假体可用于广泛的外科手术。

7. 发明申请

US20050192600A1 Inguinal hernia repair prosthetic 审中-公开
标题翻译：腹股沟疝修补假体
公开(公告)号：US20050192600A1
公开(公告)日：2005-09-01
申请号：US11065332
申请日：2005-02-24
申请人： Enrico Nicolo , Massimo Mancusso
发明人： Enrico Nicolo , Massimo Mancusso
IPC分类号： A61B17/08 , A61F2/00
CPC分类号： A61F2/0063
摘要： A suture-less, tension free, one-piece, double layer, inguinal hernia repair prosthetic is preferably formed of a single piece or sheet of repair fabric, such as polypropylene mesh, PTFE mesh, biologic material, or combinations thereof. The prosthetic sheet preferably includes a fold line dividing the sheet into two general halves. Each prosthetic half of the prosthetic sheet is preferably shaped generally to fit within the inguinal canal. Each prosthetic half of the sheet includes an opening in the inner portion of the sheet and a slit extending to the peripheral portion of the prosthetic half. The slits extend to generally opposite side of the prosthetic. Each opening is adapted to receive a patient's spermatic cord structure there through.
摘要翻译：无缝合，无张力，一体式，双层，腹股沟疝修补假体优选由单片或多片修复织物形成，例如聚丙烯网，PTFE网，生物材料或其组合。假体片优选地包括将片分成两个一般的两半的折线。假体片的每个假体半部优选地通常成形为适合于腹股沟内。片材的每个假体半部包括在片材的内部部分中的开口和延伸到假肢半部的周边部分的狭缝。狭缝延伸到假体的大致相对的一侧。每个开口适合于通过接收患者的精索结构。

8. 发明授权

US06592600B1 Bowel clamp 失效
标题翻译：肠夹
公开(公告)号：US06592600B1
公开(公告)日：2003-07-15
申请号：US09168649
申请日：1998-10-08
申请人： Enrico Nicolo
发明人： Enrico Nicolo
IPC分类号： A61B1708
CPC分类号： A61B17/29 , A61B17/0218 , A61B17/282 , A61B2017/2808 , A61B2017/2901 , A61B2017/2929 , A61B2017/2932
摘要： A surgical clamp allows for mobilization of an organ or hollow viscus of a patient during a surgical procedure with minimization of trauma to the organ or hollow viscus. The surgical clamp includes at least one handle adapted to be gripped by the user for manipulation of the surgical clamp and the engaged organ or hollow viscus, and at least on jaw attached to the handle, wherein the jaw is adapted to substantially encircle the engaged organ or hollow viscus of the patient. The clamp may be sized to fit through a conventional trocar such that the surgical procedure may be a laparoscopic procedure for operating on the organ or hollow viscus, such as the bowel.
摘要翻译：手术夹具允许在外科手术过程中移动患者的器官或中空粘液，同时使器官或中空粘液的创伤最小化。手术夹具包括至少一个手柄，其适于被使用者抓住以操纵手术夹具和被接合的器官或中空粘液，并且至少在连接到手柄上的钳口上，其中钳口适于基本上环绕接合的器官或患者的中空粘液。夹具的尺寸可以通过常规套管针的尺寸设定，使得外科手术可以是用于在器官或中空粘液（例如肠）上操作的腹腔镜手术。

9. 发明授权

US06279809B1 Circular stapler for side to end, side to side and end to side anastomosis 有权
公开(公告)号：US06279809B1
公开(公告)日：2001-08-28
申请号：US09264764
申请日：1999-03-09
申请人： Enrico Nicolo
发明人： Enrico Nicolo
IPC分类号： A61B17068
CPC分类号： A61B17/068 , A61B17/11 , A61B17/115 , A61B17/1155 , A61B2017/1135 , A61B2017/1139 , A61B2017/2905
摘要： A circular stapler for side to end, side to side or end to side anastomosis includes an actuating head portion attached to an elongated tubular body with a handle on the opposed end of the body from the head. The head includes an anvil and associated stapling mechanism, wherein the anvil and the associated stapling mechanism are positioned perpendicular to a longitudinal axis of the head. The anvil is releasably attached to the head and may be attached to the head through an anvil applicator. The anvil may include an extendable stem.

10. 发明授权

US09636203B2 Method and apparatus of tension free inguinal hernia repair reconstructing physiology using inguinal hernia prosthetic having lateral non-encircling cord locating structure 有权
公开(公告)号：US09636203B2
公开(公告)日：2017-05-02
申请号：US13078338
申请日：2011-04-01
申请人： Enrico Nicolo
发明人： Enrico Nicolo
IPC分类号： A61F2/02 , A61F2/00
CPC分类号： A61F2/0063
摘要： An inguinal hernia prosthesis includes a cord locating structure that provides cord protecting functions. The cord locating structure, which may be a semi-circular or other shaped recess positioned along a longitudinal peripheral edge of the prosthesis, is designed to only surround a portion of the cord, e.g. less than 180 or preferably 120 degrees, with the remaining cord circumference being positioned by the element against appropriate muscle tissue. The cord locating structure may be referenced as a non-encircling lateral cord locating structure. The prosthetic: provides tension free repair; minimizes cord damage through tissue ingrowth/strangulation effects, inadvertent suturing through the cord structure, and abrasion with the prosthetic; and minimizes size of prosthetic used in the repair; and is configured to reconstitutes the pre-hernia muscle physiology.

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