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1. 发明申请

US20070244556A1 Annuloplasty Device Having a Helical Anchor and Methods for its Use 审中-公开
公开(公告)号：US20070244556A1
公开(公告)日：2007-10-18
申请号：US11734566
申请日：2007-04-12
申请人： Nasser Rafiee , Nareak Douk , Eliot Bloom , Michael Finney , Morgan House , Rany Huynh , Stuart Mac Donald , Juan-Pablo Mas , David Barone
发明人： Nasser Rafiee , Nareak Douk , Eliot Bloom , Michael Finney , Morgan House , Rany Huynh , Stuart Mac Donald , Juan-Pablo Mas , David Barone
IPC分类号： A61F2/24
摘要： A system for modifying a heart valve annulus includes a helically helical anchored annuloplasty device delivered to the annulus via an elongated delivery member. The helical anchors of the devices disclosed herein are rotated into the valve annulus along an anchor guide by using a driver that is movably disposed in the delivery member. A tether is disposed within an inner channel of the helical anchor and a locking device is used to secure the annuloplasty device after the valve annulus has been modified. The annuloplasty device can be delivered to the annulus using, traditional surgical approach or a minimally invasive or catheter based methods.

2. 发明申请

US20070051377A1 Cardiac valve annulus reduction system 有权
标题翻译：心脏瓣膜减压系统
公开(公告)号：US20070051377A1
公开(公告)日：2007-03-08
申请号：US10531819
申请日：2004-11-12
申请人： Nareak Douk , Nasser Rafiee , Eliot Bloom , Douglas Fogg , Rany Huynh , David Barone
发明人： Nareak Douk , Nasser Rafiee , Eliot Bloom , Douglas Fogg , Rany Huynh , David Barone
IPC分类号： A61B19/00
CPC分类号： A61F2/2445 , A61B17/00234 , A61B17/0401 , A61B2017/00243 , A61B2017/00783 , A61B2017/0414 , A61B2017/0496 , A61B2017/06052 , A61B2017/06176 , A61F2002/30545 , A61F2220/0016 , A61F2250/001
摘要： A catheter-based, annulus reduction device and system for cardiac valve repair and method of using the same. The system is usable for treating mitral valve regurgitation and comprises a catheter, a reduction ring carried within the catheter, the reduction ring including a plurality of exit ports formed in a side wall of the reduction ring and filament received in the reduction ring. The filament includes a plurality of radially extendible barbs corresponding to the sidewall openings. The reduction ring carrying the filament is deployed adjacent a mitral valve annulus and the filament is translated relative to the reduction ring to deploy the barbs through the exit ports and into the annulus and to further translate the reduction ring with deployed barbs to reshape the annulus.
摘要翻译：一种基于导管的减压装置和心脏瓣膜修复系统及其使用方法。该系统可用于治疗二尖瓣反流，并且包括导管，在导管内承载的还原环，所述还原环包括形成在所述还原环的侧壁中的多个出口和容纳在所述还原环中的细丝。灯丝包括对应于侧壁开口的多个可径向延伸的倒钩。承载细丝的还原环被布置在二尖瓣环附近，并且细丝相对于还原环平移，以将倒钩布置在出口端口并进入环形空间中，并且进一步将还原环用展开的倒钩重新平整以环形环。

3. 发明申请

US20060167474A1 Apparatus and method for elongation of a papillary muscle 审中-公开
标题翻译：用于乳头肌伸长的装置和方法
公开(公告)号：US20060167474A1
公开(公告)日：2006-07-27
申请号：US10531832
申请日：2004-09-15
申请人： Eliot Bloom , Nasser Rafiee , Nareak Douk
发明人： Eliot Bloom , Nasser Rafiee , Nareak Douk
IPC分类号： A61B17/122 , A61B17/128 , A61F2/24
CPC分类号： A61F2/2466 , A61B90/02 , A61B2017/00243 , A61B2017/088 , A61F2/2457
摘要： A system and method for treating a dilated heart valve by elongating a papillary muscle. The system comprises a delivery catheter 110 and a holding catheter 130. The system further comprises a muscle elongation device 200 including at least two clamping rings 210, 215 slidably connected by at least one connecting rod 220. The muscle elongation device 200 is delivered to a papillary muscle 560 associated with the dilated heart valve, where it is released from the delivery catheter 110 and the clamping rings 210, 215 wrap about and engage the papillary muscle. The muscle tissue is cut between the clamping rings 210, 215, which then move away from each other to a predetermined position, thus permitting the papillary muscle to elongate.
摘要翻译：一种通过延长乳头肌来治疗扩张型心脏瓣膜的系统和方法。该系统包括输送导管110和保持导管130。系统还包括肌肉伸长装置200，其包括至少两个由至少一个连杆220可滑动地连接的夹紧环210,215。肌肉伸长装置200被输送到与扩张的心脏瓣膜相关联的乳头肌560，其中它从输送导管110释放，并且夹紧环210,215包裹并接合乳头肌。在夹紧环210,215之间切割肌肉组织，然后夹紧环210,215彼此远离移动到预定位置，从而允许乳头肌细长。

4. 发明申请

US20070093869A1 Device, system, and method for contracting tissue in a mammalian body 审中-公开
标题翻译：用于在哺乳动物体内收缩组织的装置，系统和方法
公开(公告)号：US20070093869A1
公开(公告)日：2007-04-26
申请号：US10560986
申请日：2004-06-21
申请人： Eliot Bloom , Nareak Douk , Nasser Rafiee
发明人： Eliot Bloom , Nareak Douk , Nasser Rafiee
IPC分类号： A61B17/08
CPC分类号： A61B17/068 , A61B17/0644 , A61B17/10 , A61B2017/00243 , A61B2017/0641 , A61B2017/081 , A61F2/2445
摘要： A device, a system and a method for contracting tissue in a mammalian body. The contracting device comprises a body and a plurality of legs radially splayed there from. Each leg includes a snap-acting spring tip. When a force is applied to the device, the tips operate to transform the device from a deployment state into a treatment state. Each leg may also be bent at one or more deformation elements in response to the application of force. The system comprises a contracting device slidably received within a delivery catheter. The method of contracting tissue in a mammalian body comprises delivering a contracting device in a lumen of a catheter proximate a treatment area, releasing the contracting device from the catheter, positioning legs of the contracting device on tissue to be contracted, exerting a force on the contracting device, transforming the device into a treatment state, and reducing a compass of the tissue in response to the attainment of the treatment state.
摘要翻译：用于在哺乳动物体内收缩组织的装置，系统和方法。收缩装置包括主体和在其上径向张开的多个腿。每个腿包括弹性弹簧尖。当力施加到设备时，提示操作以将设备从部署状态转换成处理状态。响应于施加力，每个腿也可以在一个或多个变形元件处弯曲。该系统包括可滑动地容纳在输送导管内的收缩装置。在哺乳动物身体中收缩组织的方法包括将收缩装置输送到靠近治疗区域的导管的内腔中，将收缩装置从导管释放，将收缩装置的腿定位在要收缩的组织上，在其上施加力收缩装置，将装置转化为治疗状态，以及响应于治疗状态的实现而减少组织的罗盘。

5. 发明授权

US07316706B2 Tensioning device, system, and method for treating mitral valve regurgitation 有权
标题翻译：张力装置，系统和二尖瓣反流治疗方法
公开(公告)号：US07316706B2
公开(公告)日：2008-01-08
申请号：US10867394
申请日：2004-06-14
申请人： Eliot Bloom , Nareak Douk , John Horrigan , Rany Huynh , Nasser Rafiee
发明人： Eliot Bloom , Nareak Douk , John Horrigan , Rany Huynh , Nasser Rafiee
IPC分类号： A61B17/04 , A61B17/08
CPC分类号： A61F2/2487 , A61B2017/00243 , A61B2017/00783 , A61B2017/0409 , A61B2017/0437 , A61B2017/0445 , A61B2017/0462 , A61B2017/0464
摘要： A system for treating mitral valve regurgitation comprises a tensioning device slidably received within a delivery catheter. The tensioning device includes a tether linking proximal an anchoring member and a distal anchoring member. At least one of the anchoring members includes an elastic portion that flexes in response to a heartbeat when the tensioning device is positioned across a chamber of a heart. The tether includes at least one locking member initially positioned between the anchoring members. A method for treating mitral valve regurgitation comprises piercing a first wall of a chamber of a heart, engaging a distal anchoring member with a second wall of the heart chamber, engaging a proximal anchoring member with the first wall, and pulling a locking member affixed to a tether linking the anchoring members from an initial position between the two anchoring members to a locked position proximal the proximal anchoring member.
摘要翻译：用于治疗二尖瓣反流的系统包括可滑动地容纳在输送导管内的张紧装置。张紧装置包括连接锚固构件和远侧锚定构件的系绳。锚固构件中的至少一个包括弹性部分，当张紧装置定位在心脏的腔室时，弹性部分响应于心跳而弯曲。系绳包括至少一个初始定位在锚定构件之间的锁定构件。一种治疗二尖瓣反流的方法包括刺穿心脏腔室的第一壁，将远端锚固构件与心脏腔室的第二壁接合，使近端锚定构件与第一壁接合，并且拉动固定到将锚定构件从两个锚定构件之间的初始位置连接到靠近近侧锚定构件的锁定位置的系绳。

6. 发明申请

US20070244554A1 Annuloplasty Device Having a Helical Anchor and Methods for its Use 审中-公开
标题翻译：具有螺旋锚的瓣环成形装置及其使用方法
公开(公告)号：US20070244554A1
公开(公告)日：2007-10-18
申请号：US11734547
申请日：2007-04-12
申请人： Nasser Rafiee , Nareak Douk , Eliot Bloom , Michael Finney , Morgan House , Rany Huynh , Stuart Mac Donald , Juan-Pablo Mas , David Barone
发明人： Nasser Rafiee , Nareak Douk , Eliot Bloom , Michael Finney , Morgan House , Rany Huynh , Stuart Mac Donald , Juan-Pablo Mas , David Barone
IPC分类号： A61F2/24
摘要： A system for modifying a heart valve annulus includes a helically helical anchored annuloplasty device delivered to the annulus via an elongated delivery member. The helical anchors of the devices disclosed herein are rotated into the valve annulus along an anchor guide by using a driver that is movably disposed in the delivery member. A tether is disposed within an inner channel of the helical anchor and a locking device is used to secure the annuloplasty device after the valve annulus has been modified. The annuloplasty device can be delivered to the annulus using, traditional surgical approach or a minimally invasive or catheter based methods.
摘要翻译：用于修改心脏瓣膜环的系统包括经由细长递送构件递送至环带的螺旋状螺旋锚定瓣环成形术装置。本文公开的装置的螺旋锚通过使用可移动地设置在输送构件中的驱动器沿着锚定引导件旋转到阀环中。系绳设置在螺旋锚固件的内部通道内，并且锁定装置用于在瓣膜环已被修改之后固定瓣环成形术装置。瓣膜成形术装置可以使用传统的手术方法或基于微创或基于导管的方法递送至环带。

7. 发明申请

US20070244553A1 Annuloplasty Device Having a Helical Anchor and Methods for its Use 有权
公开(公告)号：US20070244553A1
公开(公告)日：2007-10-18
申请号：US11734536
申请日：2007-04-12
申请人： Nasser Rafiee , Nareak Douk , Eliot Bloom , Michael Finney , Morgan House , Rany Huynh , Stuart Mac Donald , Juan-Pablo Mas , David Barone
发明人： Nasser Rafiee , Nareak Douk , Eliot Bloom , Michael Finney , Morgan House , Rany Huynh , Stuart Mac Donald , Juan-Pablo Mas , David Barone
IPC分类号： A61F2/24
CPC分类号： A61F2/2451 , A61F2/2466
摘要： A system for modifying a heart valve annulus includes a helically helical anchored annuloplasty device delivered to the annulus via an elongated delivery member. The helical anchors of the devices disclosed herein are rotated into the valve annulus along an anchor guide by using a driver that is movably disposed in the delivery member. A tether is disposed within an inner channel of the helical anchor and a locking device is used to secure the annuloplasty device after the valve annulus has been modified. The annuloplasty device can be delivered to the annulus using, traditional surgical approach or a minimally invasive or catheter based methods.

8. 发明申请

US20070244555A1 Annuloplasty Device Having a Helical Anchor and Methods for its Use 审中-公开
公开(公告)号：US20070244555A1
公开(公告)日：2007-10-18
申请号：US11734555
申请日：2007-04-12
申请人： Nasser Rafiee , Nareak Douk , Eliot Bloom , Michael Finney , Morgan House , Rany Huynh , Stuart Mac Donald , Juan-Pablo Mas , David Barone
发明人： Nasser Rafiee , Nareak Douk , Eliot Bloom , Michael Finney , Morgan House , Rany Huynh , Stuart Mac Donald , Juan-Pablo Mas , David Barone
IPC分类号： A61F2/24
CPC分类号： A61F2/2445 , A61F2/2466
摘要： A system for modifying a heart valve annulus includes a helically helical anchored annuloplasty device delivered to the annulus via an elongated delivery member. The helical anchors of the devices disclosed herein are rotated into the valve annulus along an anchor guide by using a driver that is movably disposed in the delivery member. A tether is disposed within an inner channel of the helical anchor and a locking device is used to secure the annuloplasty device after the valve annulus has been modified. The annuloplasty device can be delivered to the annulus using, traditional surgical approach or a minimally invasive or catheter based methods.

9. 发明授权

US08454683B2 Annuloplasty device having a helical anchor and methods for its use 有权
标题翻译：具有螺旋锚的瓣膜成形术装置及其使用方法
公开(公告)号：US08454683B2
公开(公告)日：2013-06-04
申请号：US11734536
申请日：2007-04-12
申请人： Nasser Rafiee , Nareak Douk , Eliot Bloom , Michael Finney , Morgan House , Rany Huynh , Stuart Mac Donald , Juan-Pablo Mas , David Barone
发明人： Nasser Rafiee , Nareak Douk , Eliot Bloom , Michael Finney , Morgan House , Rany Huynh , Stuart Mac Donald , Juan-Pablo Mas , David Barone
IPC分类号： A61F2/24
CPC分类号： A61F2/2451 , A61F2/2466
摘要： A system for modifying a heart valve annulus includes a helically helical anchored annuloplasty device delivered to the annulus via an elongated delivery member. The helical anchors of the devices disclosed herein are rotated into the valve annulus along an anchor guide by using a driver that is movably disposed in the delivery member. A tether is disposed within an inner channel of the helical anchor and a locking device is used to secure the annuloplasty device after the valve annulus has been modified. The annuloplasty device can be delivered to the annulus using, traditional surgical approach or a minimally invasive or catheter based methods.
摘要翻译：用于修改心脏瓣膜环的系统包括经由细长递送构件递送至环带的螺旋状螺旋锚定瓣环成形术装置。本文公开的装置的螺旋锚通过使用可移动地设置在输送构件中的驱动器沿着锚定引导件旋转到阀环中。系绳设置在螺旋锚固件的内部通道内，并且锁定装置用于在瓣膜环已被修改之后固定瓣环成形术装置。瓣膜成形术装置可以使用传统的手术方法或基于微创或基于导管的方法递送至环带。

10. 发明授权

US07699892B2 Minimally invasive procedure for implanting an annuloplasty device 有权
标题翻译：植入瓣膜成形术装置的微创手术
公开(公告)号：US07699892B2
公开(公告)日：2010-04-20
申请号：US11734604
申请日：2007-04-12
申请人： Nasser Rafiee , Nareak Douk , Eliot Bloom , Michael Finney , Morgan House , Rany Huynh , Stuart Mac Donald , Juan-Pablo Mas , David Barone
发明人： Nasser Rafiee , Nareak Douk , Eliot Bloom , Michael Finney , Morgan House , Rany Huynh , Stuart Mac Donald , Juan-Pablo Mas , David Barone
IPC分类号： A61F2/24
CPC分类号： A61F2/2448
摘要： A method for modifying a heart valve annulus includes placing a purse string suture at a puncture site adjacent a heart valve, inserting at least one delivery member through the puncture site, positioning a distal end of the at least one delivery member adjacent a portion of a valve annulus, deploying an annuloplasty device carried within the at least one delivery member and implanting the annuloplasty device into the valve annulus. The method also includes reshaping the heart valve annulus after implantation of the at least one annuloplasty device.
摘要翻译：一种用于修改心脏瓣膜环的方法包括将钱包线缝合物放置在心脏瓣膜附近的穿刺部位处，将至少一个递送部件穿过穿刺部位插入，将至少一个递送部件的远端邻近一部分瓣膜环，部署在所述至少一个递送构件内携带的瓣环成形术装置，并将瓣环成形术装置植入瓣膜环。该方法还包括在植入至少一个瓣膜成形术装置之后重塑心脏瓣膜环。

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