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    • 1. 发明授权
    • Method and apparatus for electrophysiological testing in an implantable device
    • 用于在可植入装置中进行电生理测试的方法和装置
    • US06847843B1
    • 2005-01-25
    • US09876755
    • 2001-06-06
    • Elia Arambula MouchawarBonian DaiMohssen FardGregory HauckCorey L. Brown
    • Elia Arambula MouchawarBonian DaiMohssen FardGregory HauckCorey L. Brown
    • A61N1/18A61N1/362A61N1/365A61N1/372
    • A61N1/365A61N1/3625
    • An implantable cardiac stimulation device and associated method capable of delivering non-invasive programmed stimulation for electrophysiological testing in which the onset of the non-invasive programmed stimulation is triggered by a cardiac event, either a detected intrinsic event or a stimulated event, occurring in the heart chamber to be tested. When a non-invasive programmed stimulation command is received by the implanted device, it switches to a routine that allows transition to a non-invasive programmed stimulation from a standard operating mode, during a refractory period. The stimulation device also provides a recovery delay following the last pulse of a non-invasive programmed stimulation sequence. If no intrinsic activity is detected during the recovery delay, a refractory period is started following the expiration of the recovery delay. During this refractory period, a transition from the non-invasive programmed stimulation state machine back to the standard stimulation state machine is accomplished.
    • 可植入的心脏刺激装置和相关联的方法,其能够递送用于电生理测试的非侵入式程序刺激,其中非侵入式程序化刺激的发作由心脏事件触发,或者检测到的固有事件或刺激事件 心室待测。 当植入装置接收非侵入式编程刺激命令时,它切换到允许在不应期内从标准操作模式转换到无创程序刺激的程序。 刺激装置还在非侵入式编程刺激序列的最后脉冲之后提供恢复延迟。 如果在恢复延迟期间没有检测到内在活动,则在恢复延迟期满后开始不应期。 在这个不应期内,实现了从无创程序刺激状态机转移到标准刺激状态机的过渡。
    • 3. 发明授权
    • Systems and methods for use with an implantable medical device for discriminating VT and SVT based on ventricular depolarization event timing
    • 用于基于心室去极化事件时间识别VT和SVT的可植入医疗装置的系统和方法
    • US08165675B2
    • 2012-04-24
    • US12608827
    • 2009-10-29
    • Hanbiao WangBonian DaiXing Pei
    • Hanbiao WangBonian DaiXing Pei
    • A61N1/36
    • A61B5/0464A61B5/053A61B5/0816A61B5/11A61B2562/0219A61N1/3622
    • Techniques are described for discriminating ventricular tachycardia (VT) from supraventricular tachycardia (SVT) using an implantable medical device capable of multi-site ventricular sensing. In one example, ventricular depolarization events are detected within a patient by the implantable device during a tachyarrhythmia, at both a left ventricular sensing site and a right ventricular sensing site. Ventricular event timing differences are then ascertained. The device compares the ventricular event timing differences detected during the tachyarrhythmia with predetermined supraventricular event timing differences for the patient, such as event timing differences previously detected within the patient during sinus rhythm or extrapolated from sinus rhythm values. The device then distinguishes VT from SVT based on the comparison of the event timing differences detected during the tachyarrhythmia with the predetermined supraventricular event timing differences. Morphological waveform analysis can also be performed, when needed, to further distinguish VT from SVT.
    • 描述了使用能够进行多部位心室感测的可植入医疗装置来区分室上性心动过速(VT)与室上性心动过速(SVT)的技术。 在一个示例中,在左心室感觉部位和右心室感测部位的快速性心律失常期间,可植入装置在患者体内检测心室去极化事件。 然后确定心室事件时间差异。 该装置将在快速性心律失常期间检测到的心室事件时间差与患者的预定的室上事件时间差相比较,例如在窦性心律期间先前在患者内检测到的事件时间差异或从窦性心律值外推。 然后,该设备基于在快速性心律失常期间检测到的事件时间差与预定的室上事件时间差异的比较来区分VT与SVT。 当需要时也可以进行形态波形分析,以进一步区分VT与SVT。
    • 5. 发明授权
    • Systems and methods for diagnosing an implantable device
    • 用于诊断植入式装置的系统和方法
    • US07991472B2
    • 2011-08-02
    • US12247841
    • 2008-10-08
    • Paul A. LevineHanbiao WangBonian DaiRobert E. Smith, Jr.
    • Paul A. LevineHanbiao WangBonian DaiRobert E. Smith, Jr.
    • A61N1/00
    • A61N1/3706A61N1/3702A61N1/371A61N2001/083
    • A method for diagnosing an implantable cardiac device including a plurality of implanted leads may include: monitoring a plurality of parameters associated with the plurality of implanted leads; detecting a change in one of the parameters; evaluating at least one of the other parameters upon detection of the change; and diagnosing a problem with the implantable cardiac device based on the detected change and the evaluation. A system for diagnosing an implantable cardiac device including a plurality of implanted leads may include an implantable pacing device and a processor. The processor may be configured to: monitor a plurality of parameters associated with the plurality of implanted leads; detect a change in one of the parameters; evaluating at least one of the other parameters upon detection of the change; and diagnose a problem with the implantable cardiac device based on the detected change and the evaluation.
    • 用于诊断包括多个植入引线的可植入心脏装置的方法可以包括:监测与所述多个植入引线相关联的多个参数; 检测其中一个参数的变化; 在检测到变化时评估至少一个其他参数; 并且基于检测到的变化和评估来诊断可植入心脏装置的问题。 用于诊断包括多个植入引线的可植入心脏装置的系统可以包括可植入起搏装置和处理器。 处理器可以被配置为:监视与多个植入引线相关联的多个参数; 检测其中一个参数的变化; 在检测到变化时评估至少一个其他参数; 并基于检测到的变化和评估来诊断可植入心脏装置的问题。
    • 6. 发明申请
    • SYSTEMS AND METHODS FOR USE WITH AN IMPLANTABLE MEDICAL DEVICE FOR DISCRIMINATING VT AND SVT BASED ON VENTRICULAR DEPOLARIZATION EVENT TIMING
    • 用于基于静态分解事件定时的用于鉴别VT和SVT的可植入医疗设备的系统和方法
    • US20110106194A1
    • 2011-05-05
    • US12608827
    • 2009-10-29
    • Hanbiao WangBonian DaiXing Pei
    • Hanbiao WangBonian DaiXing Pei
    • A61N1/365A61B5/0464
    • A61B5/0464A61B5/053A61B5/0816A61B5/11A61B2562/0219A61N1/3622
    • Techniques are described for discriminating ventricular tachycardia (VT) from supraventricular tachycardia (SVT) using an implantable medical device capable of multi-site ventricular sensing. In one example, ventricular depolarization events are detected within a patient by the implantable device during a tachyarrhythmia, at both a left ventricular sensing site and a right ventricular sensing site. Ventricular event timing differences are then ascertained. The device compares the ventricular event timing differences detected during the tachyarrhythmia with predetermined supraventricular event timing differences for the patient, such as event timing differences previously detected within the patient during sinus rhythm or extrapolated from sinus rhythm values. The device then distinguishes VT from SVT based on the comparison of the event timing differences detected during the tachyarrhythmia with the predetermined supraventricular event timing differences. Morphological waveform analysis can also be performed, when needed, to further distinguish VT from SVT.
    • 描述了使用能够进行多部位心室感测的可植入医疗装置来区分室上性心动过速(VT)与室上性心动过速(SVT)的技术。 在一个示例中,在左心室感觉部位和右心室感测部位的快速性心律失常期间,可植入装置在患者体内检测心室去极化事件。 然后确定心室事件时间差异。 该装置将在快速性心律失常期间检测到的心室事件时间差与患者的预定的室上事件时间差相比较,例如在窦性心律期间先前在患者内检测到的事件时间差异或从窦性心律值外推。 然后,该设备基于在快速性心律失常期间检测到的事件时间差与预定的室上事件时间差异的比较来区分VT与SVT。 当需要时也可以进行形态波形分析,以进一步区分VT与SVT。
    • 7. 发明申请
    • SYSTEMS AND METHODS FOR DIAGNOSING AN IMPLANTABLE DEVICE
    • 用于诊断可植入设备的系统和方法
    • US20100087891A1
    • 2010-04-08
    • US12247841
    • 2008-10-08
    • Paul A. LevineHanbiao WangBonian DaiRobert E. Smith, JR.
    • Paul A. LevineHanbiao WangBonian DaiRobert E. Smith, JR.
    • A61N1/37
    • A61N1/3706A61N1/3702A61N1/371A61N2001/083
    • A method for diagnosing an implantable cardiac device including a plurality of implanted leads may include: monitoring a plurality of parameters associated with the plurality of implanted leads; detecting a change in one of the parameters; evaluating at least one of the other parameters upon detection of the change; and diagnosing a problem with the implantable cardiac device based on the detected change and the evaluation. A system for diagnosing an implantable cardiac device including a plurality of implanted leads may include an implantable pacing device and a processor. The processor may be configured to: monitor a plurality of parameters associated with the plurality of implanted leads; detect a change in one of the parameters; evaluating at least one of the other parameters upon detection of the change; and diagnose a problem with the implantable cardiac device based on the detected change and the evaluation.
    • 用于诊断包括多个植入引线的可植入心脏装置的方法可以包括:监测与所述多个植入引线相关联的多个参数; 检测其中一个参数的变化; 在检测到变化时评估至少一个其他参数; 并且基于检测到的变化和评估来诊断可植入心脏装置的问题。 用于诊断包括多个植入引线的可植入心脏装置的系统可以包括可植入起搏装置和处理器。 处理器可以被配置为:监视与多个植入引线相关联的多个参数; 检测其中一个参数的变化; 在检测到变化时评估至少一个其他参数; 并基于检测到的变化和评估来诊断可植入心脏装置的问题。