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1. 发明申请

US20090177040A1 Instrument shaft 审中-公开
标题翻译：仪表轴
公开(公告)号：US20090177040A1
公开(公告)日：2009-07-09
申请号：US12314522
申请日：2008-12-11
申请人： Edwin Lyons , Dougles J. Rose-Innes
发明人： Edwin Lyons , Dougles J. Rose-Innes
IPC分类号： A61B1/008
CPC分类号： A61B1/0055 , A61M25/0138
摘要： A shaft for a flexible endoscopic instrument is provided in which the shaft comprises a generally tubular frame member, the tubular frame member providing the shaft with at least one flexible section along the length of the shaft, the flexible section having a greater flexibility than at least one other section of the shaft. The flexible section of the shaft has a proximal end and a distal end, and is provided with first and second series of slots, the slots of the first series alternating with the slots of the second series to form an offset pattern of staggered slots in the frame member to provide the different stiffness properties. Each of the slots in a selected one of either the first or second series of slots is of a different length as compared to other slots in that series of slots, the slots in the selected series varying in length according to a predetermined progression, such that the flexible section is designed to deflect in a controlled and predetermined manner.
摘要翻译：提供了一种用于柔性内窥镜器械的轴，其中所述轴包括大致管状的框架构件，所述管状框架构件为所述轴提供沿着所述轴的长度的至少一个柔性部分，所述柔性部分具有比至少更大的挠性轴的另一部分。轴的柔性部分具有近端和远端，并且设置有第一和第二系列槽，第一系列的槽与第二系列的槽交替，以形成位于第二系列中的交错槽的偏移图案框架构件以提供不同的刚度特性。与所述一系列时隙中的其他时隙相比，所述第一或第二时隙系列中的所选择的一个中的每个时隙具有不同的长度，所选择的系列中的时隙根据预定的进程在长度上变化，使得柔性部分被设计成以受控和预定的方式偏转。

2. 发明授权

US09308077B2 Medical device suitable for treating reflux from a stomach to an oesophagus 有权
公开(公告)号：US09308077B2
公开(公告)日：2016-04-12
申请号：US11643698
申请日：2006-12-22
申请人： Niall Behan , Donal Devery , Sean Finnegan , Edwin Lyons , Enda McLaughlin
发明人： Niall Behan , Donal Devery , Sean Finnegan , Edwin Lyons , Enda McLaughlin
IPC分类号： A61F2/04 , A61B17/00 , A61F2/24 , A61F2/91 , A61F2/95
CPC分类号： A61F2/04 , A61B2017/00827 , A61F2/24 , A61F2/2418 , A61F2/90 , A61F2/91 , A61F2/95 , A61F2002/044 , A61F2250/0039 , A61F2250/0067
摘要： A medical treatment device (200), for treating reflux from a stomach (201) to an esophagus (202) and for delivering a therapeutic agent to an inner surface of the esophagus (202), comprises a valve member (203), a lining member (204), and a support member (205). The valve member (203) is movable between a closed configuration and an open configuration, in which the valve member (203) facilitates passage of material between the esophagus (202) and the stomach (201). The valve member (203) is biased towards the closed configuration and gradually moves over a period of 4 to 10 secs from the open configuration to the closed configuration. The support member (205) supports the device (200) relative to the esophagus (202) and the stomach (201). The lining member (204) lines part of the inner surface of the esophagus (202) for delivery of a therapeutic agent to the esophagus (202).

3. 发明授权

US08603188B2 Medical device suitable for treating reflux from a stomach to an oesophagus 有权
标题翻译：适用于治疗从胃向食道返回的医疗装置
公开(公告)号：US08603188B2
公开(公告)日：2013-12-10
申请号：US12837023
申请日：2010-07-15
申请人： Niall Behan , Donal Devery , Sean Finnegan , Edwin Lyons , Enda McLaughlin
发明人： Niall Behan , Donal Devery , Sean Finnegan , Edwin Lyons , Enda McLaughlin
IPC分类号： A61F2/04
CPC分类号： A61F2/04 , A61B2017/00827 , A61F2/24 , A61F2/2418 , A61F2/90 , A61F2/91 , A61F2/95 , A61F2002/044 , A61F2250/0039 , A61F2250/0067
摘要： A medical treatment device (200), for treating reflux from a stomach (201) to an esophagus (202) and for delivering a therapeutic agent to an inner surface of the esophagus (202), comprises a valve member (203), a lining member (204), and a support member (205). The valve member (203) is movable between a closed configuration and an open configuration, in which the valve member (203) facilitates passage of material between the esophagus (202) and the stomach (201). The valve member (203) is biased towards the closed configuration and gradually moves over a period of 4 to 10 secs from the open configuration to the closed configuration. The support member (205) supports the device (200) relative to the esophagus (202) and the stomach (201). The lining member (204) lines part of the inner surface of the esophagus (202) for delivery of a therapeutic agent to the esophagus (202).
摘要翻译：一种用于治疗从胃（201）到食道（202）的回流并将治疗剂输送到食道（202）的内表面的治疗装置（200），包括阀构件（203），衬垫构件（204）和支撑构件（205）。阀构件（203）可在封闭构造和打开构型之间移动，其中阀构件（203）有助于材料在食道（202）和胃（201）之间的通过。阀构件（203）被朝向闭合构型偏置，并且从打开构型到关闭构型逐渐移动4至10秒的时间。支撑构件（205）相对于食道（202）和胃（201）支撑装置（200）。衬里构件（204）排列食道（202）的内表面的一部分，用于将治疗剂递送到食道（202）。

4. 发明申请

US20100280613A1 MEDICAL DEVICE SUITABLE FOR TREATING REFLUX FROM A STOMACH TO AN OESOPHAGUS 有权
公开(公告)号：US20100280613A1
公开(公告)日：2010-11-04
申请号：US12837032
申请日：2010-07-15
申请人： Niall Behan , Donal Devery , Sean Finnegan , Edwin Lyons , Enda McLaughlin
发明人： Niall Behan , Donal Devery , Sean Finnegan , Edwin Lyons , Enda McLaughlin
IPC分类号： A61F2/08
CPC分类号： A61F2/04 , A61B2017/00827 , A61F2/24 , A61F2/2418 , A61F2/90 , A61F2/91 , A61F2/95 , A61F2002/044 , A61F2250/0039 , A61F2250/0067
摘要： A medical treatment device (200), for treating reflux from a stomach (201) to an oesophagus (202) and for delivering a therapeutic agent to an inner surface of the oesophagus (202), comprises a valve member (203), a lining member (204), and a support member (205). The valve member (203) is movable between a closed configuration and an open configuration, in which the valve member (203) facilitates passage of material between the oesophagus (202) and the stomach (201). The valve member (203) is biased towards the closed configuration and gradually moves over a period of 4 to 10 secs from the open configuration to the closed configuration. The support member (205) supports the device (200) relative to the oesophagus (202) and the stomach (201). The lining member (204) lines part of the inner surface of the oesophagus (202) for delivery of a therapeutic agent to the oesophagus (202).

5. 发明授权

US08603189B2 Medical device suitable for treating reflux from a stomach to an oesophagus 有权
标题翻译：适用于治疗从胃向食道返回的医疗装置
公开(公告)号：US08603189B2
公开(公告)日：2013-12-10
申请号：US12837032
申请日：2010-07-15
申请人： Niall Behan , Donal Devery , Sean Finnegan , Edwin Lyons , Enda McLaughlin
发明人： Niall Behan , Donal Devery , Sean Finnegan , Edwin Lyons , Enda McLaughlin
IPC分类号： A61F2/04
CPC分类号： A61F2/04 , A61B2017/00827 , A61F2/24 , A61F2/2418 , A61F2/90 , A61F2/91 , A61F2/95 , A61F2002/044 , A61F2250/0039 , A61F2250/0067
摘要： A medical treatment device (200), for treating reflux from a stomach (201) to an oesophague (202) and for delivering a therapeutic agent to an inner surface of the oesophague (202), comprises a valve member (203), a lining member (204), and a support member (205). The valve member (203) is movable between a closed configuration and an open configuration, in which the valve member (203) facilitates passage of material between the oesophague (202) and the stomach (201). The valve member (203) is biased towards the closed configuration and gradually moves over a period of 4 to 10 secs from the open configuration to the closed configuration. The support member (205) supports the device (200) relative to the oesophague (202) and the stomach (201). The lining member (204) lines part of the inner surface of the oesophague (202) for delivery of a therapeutic agent to the oesophague (202).
摘要翻译：一种用于治疗从胃（201）到食虫（202）的回流并将治疗剂输送到食道（202）的内表面的治疗装置（200），包括阀构件（203），衬垫构件（204）和支撑构件（205）。阀构件（203）可在封闭构造和打开构型之间移动，其中阀构件（203）有助于食物（202）和胃（201）之间的材料通过。阀构件（203）被朝向闭合构型偏置，并且从打开构型到关闭构型逐渐移动4至10秒的时间。支撑构件（205）相对于食虫（202）和胃（201）支撑装置（200）。衬里构件（204）排列食道（202）的内表面的一部分，用于将治疗剂递送到食洞（202）。

6. 发明申请

US20090104640A1 Method of Evaluating Biological Material and Bioreactor Therefor 审中-公开
标题翻译：生物材料和生物反应器评估方法
公开(公告)号：US20090104640A1
公开(公告)日：2009-04-23
申请号：US11575254
申请日：2005-09-14
申请人： Valerie Barron , Linda Ann Murphy , Edwin Lyons , Abhay Pandit , Peter Mc Hugh
发明人： Valerie Barron , Linda Ann Murphy , Edwin Lyons , Abhay Pandit , Peter Mc Hugh
IPC分类号： C12Q1/02 , C12M1/00 , G06F19/00
CPC分类号： A61F2/062 , G01N33/5082
摘要： A method of evaluating biological material comprising forming a 3-dimensional scaffold of tubular biological material, delivering a fluid through the tubular biological material, and evaluating the biological material and in particular evaluating the effect of biomolecules, medical devices and medical devices containing biomolecules on biological material. The invention further relates to a bioreactor suitable for evaluating biological material.
摘要翻译：一种评估生物材料的方法，包括形成管状生物材料的3维支架，通过管状生物材料输送流体，评价生物材料，特别是评价生物分子，医疗装置和含有生物分子的生物分子对生物体的影响材料。本发明还涉及适于评估生物材料的生物反应器。

7. 发明授权

US08241320B2 Surgical instrument 有权
标题翻译：手术器械
公开(公告)号：US08241320B2
公开(公告)日：2012-08-14
申请号：US12320017
申请日：2009-01-14
申请人： Edwin Lyons , Douglas J. Rose-Innes , Robert J. Brewer
发明人： Edwin Lyons , Douglas J. Rose-Innes , Robert J. Brewer
IPC分类号： A61B17/00 , A61B18/18
CPC分类号： A61B17/2909 , A61B18/1482 , A61B2017/003 , A61B2017/2927
摘要： An articulated surgical instrument includes a handle, an actuating assembly associated with the handle, and a shaft including a proximal end coupled to the handle, a deflectable portion and an end effector. Distal portions of deflection wires are connected to the shaft. Proximal portions of the wires are connected to the actuating assembly. Movement of the actuating assembly moves the deflection wires to cause a deflection of the deflectable portion. The actuating assembly includes one or more actuators and one or more slider members associated with the actuators and connected to the deflection wires. The slider members are movable linearly between first and second positions, the proximal portions of the deflection wires being connected to the slider members. One of the actuators and slider members has a cam track and the other has a cam follower, such that movement of an actuator by the user of the instrument causes a linear movement of a slider member from its first position to its second position, so as to move the deflection wires causing a corresponding deflection of the deflectable portion.
摘要翻译：关节式手术器械包括手柄，与手柄相关联的致动组件，以及包括联接到手柄的近端的轴，可偏转部分和端部执行器。偏转线的远端连接到轴。电线的近端连接到致动组件。致动组件的移动使偏转线移动以引起可偏转部分的偏转。致动组件包括一个或多个致动器和与致动器相关联并连接到偏转线的一个或多个滑块构件。滑块构件可在第一位置和第二位置之间线性移动，偏转线的近侧部分连接到滑块构件。致动器和滑动构件中的一个具有凸轮轨道，而另一个具有凸轮从动件，使得致动器由仪器使用者的运动导致滑块构件从其第一位置到其第二位置的线性运动，因此以移动导致可偏转部分的相应偏转的偏转线。

8. 发明申请

US20100298951A1 MEDICAL DEVICE SUITABLE FOR TREATING REFLUX FROM A STOMACH TO AN OESOPHAGUS 有权
标题翻译：医疗器械适用于治疗反射镜从静脉注射到ESOPHAGUS
公开(公告)号：US20100298951A1
公开(公告)日：2010-11-25
申请号：US12837023
申请日：2010-07-15
申请人： Niall Behan , Donal Devery , Sean Finnegan , Edwin Lyons , Enda McLaughlin
发明人： Niall Behan , Donal Devery , Sean Finnegan , Edwin Lyons , Enda McLaughlin
IPC分类号： A61F2/04
CPC分类号： A61F2/04 , A61B2017/00827 , A61F2/24 , A61F2/2418 , A61F2/90 , A61F2/91 , A61F2/95 , A61F2002/044 , A61F2250/0039 , A61F2250/0067
摘要： A medical treatment device (200), for treating reflux from a stomach (201) to an oesophagus (202) and for delivering a therapeutic agent to an inner surface of the oesophagus (202), comprises a valve member (203), a lining member (204), and a support member (205). The valve member (203) is movable between a closed configuration and an open configuration, in which the valve member (203) facilitates passage of material between the oesophagus (202) and the stomach (201). The valve member (203) is biased towards the closed configuration and gradually moves over a period of 4 to 10 secs from the open configuration to the closed configuration. The support member (205) supports the device (200) relative to the oesophagus (202) and the stomach (201). The lining member (204) lines part of the inner surface of the oesophagus (202) for delivery of a therapeutic agent to the oesophagus (202).
摘要翻译：一种用于治疗从胃（201）到食道（202）的回流并将治疗剂输送到食道（202）的内表面的治疗装置（200），包括阀构件（203），衬垫构件（204）和支撑构件（205）。阀构件（203）可在封闭构造和打开构型之间移动，其中阀构件（203）有助于材料在食道（202）和胃（201）之间的通过。阀构件（203）被朝向闭合构型偏置，并且从打开构型到关闭构型逐渐移动4至10秒的时间。支撑构件（205）相对于食道（202）和胃（201）支撑装置（200）。衬里构件（204）排列食道（202）的内表面的一部分，用于将治疗剂递送到食道（202）。

9. 发明申请

US20090187185A1 Surgical instrument 有权
标题翻译：手术器械
公开(公告)号：US20090187185A1
公开(公告)日：2009-07-23
申请号：US12320017
申请日：2009-01-14
申请人： Edwin Lyons , Douglas J. Rose-Innes , Robert J. Brewer
发明人： Edwin Lyons , Douglas J. Rose-Innes , Robert J. Brewer
IPC分类号： A61B18/14 , A61B19/00 , A61B17/28
CPC分类号： A61B17/2909 , A61B18/1482 , A61B2017/003 , A61B2017/2927
摘要： An articulated surgical instrument includes a handle, an actuating assembly associated with the handle, and a shaft including a proximal end coupled to the handle, a deflectable portion and an end effector. Distal portions of deflection wires are connected to the shaft. Proximal portions of the wires are connected to the actuating assembly. Movement of the actuating assembly moves the deflection wires to cause a deflection of the deflectable portion. The actuating assembly includes one or more actuators and one or more slider members associated with the actuators and connected to the deflection wires. The slider members are movable linearly between first and second positions, the proximal portions of the deflection wires being connected to the slider members. One of the actuators and slider members has a cam track and the other has a cam follower, such that movement of an actuator by the user of the instrument causes a linear movement of a slider member from its first position to its second position, so as to move the deflection wires causing a corresponding deflection of the deflectable portion.
摘要翻译：关节式手术器械包括手柄，与手柄相关联的致动组件，以及包括联接到手柄的近端的轴，可偏转部分和端部执行器。偏转线的远端连接到轴。电线的近端连接到致动组件。致动组件的移动使偏转线移动以引起可偏转部分的偏转。致动组件包括一个或多个致动器和与致动器相关联并连接到偏转线的一个或多个滑块构件。滑块构件可在第一位置和第二位置之间线性移动，偏转线的近侧部分连接到滑块构件。致动器和滑动构件中的一个具有凸轮轨道，而另一个具有凸轮从动件，使得致动器由仪器使用者的运动导致滑块构件从其第一位置到其第二位置的线性运动，因此以移动导致可偏转部分的相应偏转的偏转线。

10. 发明申请

US20070198048A1 Medical device suitable for treating reflux from a stomach to an oesophagus 有权
标题翻译：适用于治疗从胃向食道返回的医疗装置
公开(公告)号：US20070198048A1
公开(公告)日：2007-08-23
申请号：US11643698
申请日：2006-12-22
申请人： Niall Behan , Donal Devery , Sean Finnegan , Edwin Lyons , Enda McLaughlin
发明人： Niall Behan , Donal Devery , Sean Finnegan , Edwin Lyons , Enda McLaughlin
IPC分类号： A61F2/00 , A61M29/00 , A61B17/08
CPC分类号： A61F2/04 , A61B2017/00827 , A61F2/24 , A61F2/2418 , A61F2/90 , A61F2/91 , A61F2/95 , A61F2002/044 , A61F2250/0039 , A61F2250/0067
摘要： A medical treatment device (200), for treating reflux from a stomach (201) to an oesophagus (202) and for delivering a therapeutic agent to an inner surface of the oesophagus (202), comprises a valve member (203), a lining member (204), and a support member (205). The valve member (203) is movable between a closed configuration and an open configuration, in which the valve member (203) facilitates passage of material between the oesophagus (202) and the stomach (201). The valve member (203) is biased towards the closed configuration and gradually moves over a period of 4 to 10 secs from the open configuration to the closed configuration. The support member (205) supports the device (200) relative to the oesophagus (202) and the stomach (201). The lining member (204) lines part of the inner surface of the oesophagus (202) for delivery of a therapeutic agent to the oesophagus (202).
摘要翻译：一种用于治疗从胃（201）到食道（202）的回流并将治疗剂输送到食道（202）的内表面的治疗装置（200），包括阀构件（203），衬垫构件（204）和支撑构件（205）。阀构件（203）可在封闭构造和打开构型之间移动，其中阀构件（203）有助于材料在食道（202）和胃（201）之间的通过。阀构件（203）被朝向闭合构型偏置，并且从打开构型到关闭构型逐渐移动4至10秒的时间。支撑构件（205）相对于食道（202）和胃（201）支撑装置（200）。衬里构件（204）排列食道（202）的内表面的一部分，用于将治疗剂递送到食道（202）。

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