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1. 发明申请

US20110230700A1 EXPANDABLE BRACHYTHERAPY APPARATUS AND METHODS FOR USING THEM 有权
标题翻译：可扩展的宽带设备及其使用方法
公开(公告)号：US20110230700A1
公开(公告)日：2011-09-22
申请号：US12727209
申请日：2010-03-18
申请人： Eduardo Chi Sing , Tommy G. Nguyen , Luis R. Urquidi
发明人： Eduardo Chi Sing , Tommy G. Nguyen , Luis R. Urquidi
IPC分类号： A61M36/12
CPC分类号： A61N5/1015 , A61M25/10 , A61M29/02 , A61N2005/1004
摘要： Brachytherapy treatment apparatus are provided that include an elongate body including a core member and an outer member surrounding and movable relative to the core member. One or more helical catheters are provided on a distal portion of the elongate body, e.g., including distal ends coupled to the core member and proximal ends coupled to the outer member. The outer member is movable relative to the core member, e.g., axially and/or rotationally, to direct the helical catheters between a collapsed configuration for introduction through a tissue tract to a target location, e.g., a lumpectomy cavity, and an expanded configuration. Each helical catheter includes a lumen, and, after expansion to the expanded configuration, a source of radiation may be introduced along the helical catheters and/or a lumen of the core member for delivering radiation to the target location. Optionally, the apparatus may include a balloon surrounding or within the helical members.
摘要翻译：提供了近程放射疗法治疗装置，其包括细长体，其包括芯部件和围绕并可相对于芯部件移动的外部部件。一个或多个螺旋导管设置在细长主体的远端部分上，例如包括联接到芯部件的远端和与外部部件相连的近端。外部构件可相对于芯构件例如轴向和/或旋转地移动，以将螺旋形导管引导到折叠构型之间，用于通过组织管道引导到目标位置，例如乳房切除腔，以及扩张构型。每个螺旋导管包括内腔，并且在膨胀到扩张构型之后，可以沿着螺旋形导管和/或芯构件的内腔引入辐射源，以将辐射传送到目标位置。可选地，该装置可以包括围绕或在螺旋构件内的气球。

2. 发明授权

US08814775B2 Expandable brachytherapy apparatus and methods for using them 有权
标题翻译：可扩展近距离放射治疗仪及其使用方法
公开(公告)号：US08814775B2
公开(公告)日：2014-08-26
申请号：US12727209
申请日：2010-03-18
申请人： Eduardo Chi Sing , Tommy G. Nguyen , Luis R. Urquidi
发明人： Eduardo Chi Sing , Tommy G. Nguyen , Luis R. Urquidi
IPC分类号： A61N5/00 , A61M29/02 , A61N5/10 , A61M25/10
CPC分类号： A61N5/1015 , A61M25/10 , A61M29/02 , A61N2005/1004
摘要： Brachytherapy treatment apparatus are provided that include an elongate body including a core member and an outer member surrounding and movable relative to the core member. One or more helical catheters are provided on a distal portion of the elongate body, e.g., including distal ends coupled to the core member and proximal ends coupled to the outer member. The outer member is movable relative to the core member, e.g., axially and/or rotationally, to direct the helical catheters between a collapsed configuration for introduction through a tissue tract to a target location, e.g., a lumpectomy cavity, and an expanded configuration. Each helical catheter includes a lumen, and, after expansion to the expanded configuration, a source of radiation may be introduced along the helical catheters and/or a lumen of the core member for delivering radiation to the target location. Optionally, the apparatus may include a balloon surrounding or within the helical members.
摘要翻译：提供了近程放射疗法治疗装置，其包括细长体，其包括芯部件和围绕并可相对于芯部件移动的外部部件。一个或多个螺旋导管设置在细长主体的远端部分上，例如包括联接到芯部件的远端和与外部部件相连的近端。外部构件可相对于芯构件例如轴向和/或旋转地移动，以将螺旋形导管引导到折叠构型之间，用于通过组织管道引导到目标位置，例如乳房切除腔，以及扩张构型。每个螺旋导管包括内腔，并且在膨胀到扩张构型之后，可以沿着螺旋形导管和/或芯构件的内腔引入辐射源，以将辐射传送到目标位置。可选地，该装置可以包括围绕或在螺旋构件内的气球。

3. 发明授权

US07029489B1 System and method for delivering hemostasis promoting material to a blood vessel puncture site 有权
标题翻译：将止血促进材料输送到血管穿刺部位的系统和方法
公开(公告)号：US07029489B1
公开(公告)日：2006-04-18
申请号：US10461035
申请日：2003-06-13
申请人： Mark Ashby , Luis R. Urquidi , Eduardo Chi Sing
发明人： Mark Ashby , Luis R. Urquidi , Eduardo Chi Sing
IPC分类号： A61B17/08
CPC分类号： A61B17/0057 , A61B2017/00637 , A61B2017/00654 , A61B2017/00672
摘要： A system for delivering hemostasis promoting material of the present invention allows the hemostasis promoting material to be delivered to a blood vessel puncture site by fluid pressure. The system allows the hemostasis promoting material to be delivered through an introducer sheath which is already in place within a tissue tract. This system includes a controlled tip which is insertable through the introducer sheath to locate and occlude the blood vessel puncture site and a hydration chamber for receiving and delivering the hemostasis promoting material to the blood vessel puncture site. The system accurately locates the blood vessel wall at a puncture site and for properly placing a hemostasis plug over the puncture site.
摘要翻译：用于输送本发明止血促进材料的系统允许止血促进材料通过流体压力输送到血管穿刺部位。该系统允许止血促进材料通过已经在组织管内已经就位的导引器鞘被递送。该系统包括可控制的尖端，其可插入穿过引导器护套以定位和闭塞血管穿刺部位，以及用于接收和输送止血促进材料到血管穿刺部位的水合室。系统准确地将穿刺部位的血管壁定位，并将止血塞适当地放置在穿刺部位上。

4. 发明授权

US08317821B1 Release mechanism 有权
标题翻译：释放机制
公开(公告)号：US08317821B1
公开(公告)日：2012-11-27
申请号：US10462064
申请日：2003-06-12
申请人： Mark Ashby , Eduardo Chi Sing , Luis R. Urquidi , Tin Tran
发明人： Mark Ashby , Eduardo Chi Sing , Luis R. Urquidi , Tin Tran
IPC分类号： A61B17/03
CPC分类号： A61B17/0057 , A61B2017/00654 , A61B2017/00672 , A61B2017/00898 , A61B2017/3419 , A61B2017/3482
摘要： The present invention provides for a method and apparatus related to a releasable mechanism having a first connector having a first end and a second end, a second connector having a top and a bottom, a first notch positioned near the first connector second end to releasably mate with the second connector bottom, and a second notch located near the second connector bottom to releasably receive the first connector second end.
摘要翻译：本发明提供了一种与可释放机构相关的方法和装置，其具有第一连接器，其具有第一端和第二端，具有顶部和底部的第二连接器，位于第一连接器第二端附近的第一切口以可释放地配合以及位于第二连接器底部附近的可释放地接收第一连接器第二端的第二凹口。

5. 发明授权

US07037322B1 System and method for delivering hemostasis promoting material to a blood vessel puncture with a staging tube 有权
标题翻译：用止血管将止血促进材料输送到血管穿刺的系统和方法
公开(公告)号：US07037322B1
公开(公告)日：2006-05-02
申请号：US10461006
申请日：2003-06-13
申请人： Eduardo Chi Sing , Mark Ashby , Luis R. Urquidi
发明人： Eduardo Chi Sing , Mark Ashby , Luis R. Urquidi
IPC分类号： A61B17/08
CPC分类号： A61B17/0057 , A61B17/00491 , A61B2017/00637 , A61B2017/00654 , A61B2017/00672 , A61B2090/062
摘要： A system for delivering hemostasis promoting material of the present invention allows the hemostasis promoting material to be delivered to a blood vessel puncture site by fluid pressure. The system allows the hemostasis promoting material to be delivered through an introducer sheath which is already in place within a tissue tract. This system includes a controlled tip which is insertable through the introducer sheath to locate and occlude the blood vessel puncture site and a hydration chamber for receiving and delivering the hemostasis promoting material to the blood vessel puncture site. The system accurately locates the blood vessel wall at a puncture site and for properly placing a hemostasis plug over the puncture site.
摘要翻译：用于输送本发明止血促进材料的系统允许止血促进材料通过流体压力输送到血管穿刺部位。该系统允许止血促进材料通过已经在组织管内已经就位的导引器鞘被递送。该系统包括可控制的尖端，其可插入穿过引导器护套以定位和闭塞血管穿刺部位，以及用于接收和输送止血促进材料到血管穿刺部位的水合室。系统准确地将穿刺部位的血管壁定位，并将止血塞适当地放置在穿刺部位上。

6. 发明授权

US07695492B1 Enhanced bleed back system 失效
标题翻译：增强排气系统
公开(公告)号：US07695492B1
公开(公告)日：2010-04-13
申请号：US10462065
申请日：2003-06-12
申请人： Mark Ashby , Andrew H. Cragg , Luis R. Urquidi , Eduardo Chi Sing
发明人： Mark Ashby , Andrew H. Cragg , Luis R. Urquidi , Eduardo Chi Sing
IPC分类号： A61M5/00
CPC分类号： A61B17/0057 , A61B2017/00637 , A61B2017/00672 , A61B2090/062
摘要： The present invention provides for an apparatus to locate a blood vessel puncture having a bleed back entrance port near a first end, a bleed back exit port near a second end; and a lumen extending between the bleed back entrance port and the bleed back exit port, wherein said bleed back entrance port has a diameter substantially equal to or greater than the lumen diameter. The present invention further provides for a method for locating a blood vessel puncture by inserting a locator into a blood vessel lumen, the locator having a bleed back entrance port at a first end, a bleed back exit port at a second end, and a finger adjacent the bleed back entrance port, observing a blood flow out of the bleed back exit port, and withdrawing the locator out of the blood vessel lumen until the finger contacts the blood vessel wall.
摘要翻译：本发明提供一种装置，用于定位在第一端附近具有排泄口入口的血管穿刺，靠近第二端的排出口; 以及在所述排泄口入口和所述排泄口出口之间延伸的内腔，其中所述排泄口入口具有基本上等于或大于所述管腔直径的直径。本发明还提供一种通过将定位器插入血管内腔来定位血管穿刺的方法，所述定位器在第一端具有排出口入口，在第二端具有排出口，并且在手指邻近排出口入口，观察从出血口出口的血液流出，并将定位器从血管腔排出，直到手指接触血管壁。

7. 发明授权

US09883919B2 Brachytherapy apparatus, systems, and methods for using them 有权
公开(公告)号：US09883919B2
公开(公告)日：2018-02-06
申请号：US12841111
申请日：2010-07-21
申请人： Eduardo Chi Sing , Tommy G. Nguyen
发明人： Eduardo Chi Sing , Tommy G. Nguyen
IPC分类号： A61M36/04 , A61B90/00 , A61N5/10 , A61M25/01
CPC分类号： A61B90/39 , A61B2090/3925 , A61M25/0108 , A61N5/1027
摘要： A brachytherapy treatment apparatus is provided that includes a center catheter including proximal and distal ends defining a central longitudinal axis therebetween, the center catheter including a bend between the proximal and distal ends. The apparatus includes a pair of expandable catheters including pathways extending between the proximal and distal ends thereof, the expandable catheter distal ends coupled to the distal end of the core member. An actuator is coupled to the expandable catheters adjacent expandable portions that is movable relative to the center catheter for moving the expandable portions between a collapsed configuration wherein the expandable portions extend substantially parallel to the center catheter and an expanded configuration wherein the expandable portions bow away from one another substantially within a curved plane aligned generally with a bend of to the center catheter. A balloon is provided adjacent the expandable portions and surrounding a portion of the catheters.

8. 发明授权

US08636635B2 Brachytherapy apparatus, systems, and methods for using them 有权
标题翻译：近距离放射治疗仪器，系统和使用方法
公开(公告)号：US08636635B2
公开(公告)日：2014-01-28
申请号：US12543469
申请日：2009-08-18
申请人： Eduardo Chi Sing , Tommy G. Nguyen
发明人： Eduardo Chi Sing , Tommy G. Nguyen
IPC分类号： A61N5/00 , A61M36/00
CPC分类号： A61N5/1015 , A61N5/1016
摘要： An applicator for delivering brachytherapy includes elongate members movable between collapsed and expanded configurations for delivering brachytherapy within a lumpectomy cavity, a vaginal cavity, or other target region. The elongate members may be expandable into a symmetrical or asymmetrical expanded configuration, e.g., into a generally spherical, pear-shaped, or planar configuration. A system for delivering brachytherapy includes the applicator and an access device for lining and/or dilating a body cavity and/or for receiving the applicator therein. The access device is advanced into a body cavity, an expandable member on the access device is inflated, the applicator is advanced into the access device, and the elongate members are expanded to deliver radiation to the target region. Alternatively, the access device carries an expandable device into the target region, the expandable device is removed after dilating the target region, and the applicator is introduced through the access device to deliver radiation.
摘要翻译：用于递送近距离放射治疗的施放器包括可在塌陷和膨胀构型之间移动的细长构件，用于在乳房切除腔，阴道腔或其它目标区域内输送近距离放射治疗。细长构件可以可扩展成对称或不对称的膨胀构型，例如，变成大致球形的梨形或平面构型。用于递送近距离放射治疗的系统包括施用器和用于衬里和/或扩张体腔和/或用于在其中接收施用器的进入装置。进入装置前进到体腔中，进入装置上的可膨胀构件被充气，施加器前进到进入装置中，并且细长构件被扩张以将辐射传递到目标区域。或者，接入设备将可扩展设备携带到目标区域中，在扩大目标区域之后移除可扩展设备，并且通过接入设备引入施加器以传送辐射。

9. 发明申请

US20120108881A1 EXPANDABLE BRACHYTHERAPY APPARATUS AND METHODS FOR USING THEM 有权
标题翻译：可扩展的宽带设备及其使用方法
公开(公告)号：US20120108881A1
公开(公告)日：2012-05-03
申请号：US12939121
申请日：2010-11-03
申请人： Eduardo Chi Sing , Tommy G. Nguyen
发明人： Eduardo Chi Sing , Tommy G. Nguyen
IPC分类号： A61M36/04
CPC分类号： A61N5/1015 , A61M25/10 , A61N5/1001 , A61N5/1002 , A61N5/1007 , A61N5/1014 , A61N2005/1004
摘要： Brachytherapy treatment apparatus are provided that include an elongate core member, a plurality of expandable catheters or other elongate members and a balloon or other expandable member on a distal portion adjacent the core member. Each catheter includes a distal end coupled to the core member distal end, a proximal end movable relative to the core member, and a lumen extending between the proximal and distal ends for receiving a source of radiation therealong. The balloon is expandable independently of the catheters such that the balloon may be expanded after expanding the catheters, e.g., to facilitate imaging and/or dose planning. Optionally, a working channel may be provided for receiving an aspiration catheter or other instrument or at least one of the catheters may include an aspiration lumen and one or more ports, e.g., for aspirating material from a region surrounding the distal portion.
摘要翻译：提供了近距离放射疗法治疗装置，其包括细长芯部件，多个可膨胀导管或其它细长部件以及邻近该芯部件的远侧部分上的球囊或其它可扩张部件。每个导管包括联接到芯构件远端的远端，可相对于芯构件移动的近端，以及在近端和远端之间延伸的腔，用于在其周围接收辐射源。气囊可以独立于导管扩张，使得气囊可以在扩张导管之后膨胀，例如以便于成像和/或剂量计划。可选地，可以提供工作通道用于接收抽吸导管或其他器械，或者至少一个导管可以包括抽吸腔和一个或多个端口，例如用于从围绕远端部分的区域抽吸材料。

10. 发明申请

US20100048977A1 BRACHYTHERAPY APPARATUS, SYSTEMS, AND METHODS FOR USING THEM 有权
公开(公告)号：US20100048977A1
公开(公告)日：2010-02-25
申请号：US12543463
申请日：2009-08-18
申请人： Eduardo Chi Sing , Tommy G. Nguyen
发明人： Eduardo Chi Sing , Tommy G. Nguyen
IPC分类号： A61M36/10 , A61M36/12
CPC分类号： A61N5/1015 , A61N5/1016
摘要： An applicator for delivering brachytherapy includes elongate members movable between collapsed and expanded configurations for delivering brachytherapy within a lumpectomy cavity, a vaginal cavity, or other target region. The elongate members may be expandable into a symmetrical or asymmetrical expanded configuration, e.g., into a generally spherical, pear-shaped, or planar configuration. A system for delivering brachytherapy includes the applicator and an access device for lining and/or dilating a body cavity and/or for receiving the applicator therein. The access device is advanced into a body cavity, an expandable member on the access device is inflated, the applicator is advanced into the access device, and the elongate members are expanded to deliver radiation to the target region. Alternatively, the access device carries an expandable device into the target region, the expandable device is removed after dilating the target region, and the applicator is introduced through the access device to deliver radiation.

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