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1. 发明授权

US12121439B2 Biased distal assemblies with locking mechanism 有权
公开(公告)号：US12121439B2
公开(公告)日：2024-10-22
申请号：US17484203
申请日：2021-09-24
申请人： EVALVE, INC.
发明人： Chad Abunassar
IPC分类号： A61F2/24 , A61B17/00
CPC分类号： A61F2/2466 , A61B17/00234 , A61F2/2454 , A61F2/246 , A61B2017/00243 , A61F2210/0014 , A61F2220/0016 , A61F2220/0041 , A61F2220/0091
摘要： System for fixation of native leaflets of a heart valve including an implantable fixation device including a center portion defining a longitudinal axis. The implantable fixation device further includes a first distal assembly having a first distal strut pivotally-coupled with the center portion and a first distal element pivotally-coupled with the first distal strut. The first distal assembly is configured to move between a closed position and an extended position. The implantable fixation device further includes a second distal assembly having a second distal strut pivotally-coupled with the center portion and a second distal element pivotally-coupled with the second distal strut. The second distal assembly is configured to move between a closed position and an extended position. The implantable fixation device further includes a locking mechanism configured to lock the first distal assembly and second distal assembly in a selected locked position between the closed position and the extended position.

2. 发明公开

US20230248521A1 WIDE CLIP WITH NONDEFORMABLE WINGS 审中-公开
公开(公告)号：US20230248521A1
公开(公告)日：2023-08-10
申请号：US18303363
申请日：2023-04-19
申请人： EVALVE, INC.
发明人： Chad Abunassar , Jessie Garcia , Gabriel Gonzales , Samir Jain , Casey Barbarino , Santosh Prabhu
IPC分类号： A61F2/24
CPC分类号： A61F2/246 , A61F2220/0008 , A61F2230/0093 , A61F2250/0036 , A61F2250/0037
摘要： Fixation device for fixation of leaflets of a heart valve includes a central assembly and at least one arm moveably coupled to the central assembly. The at least one arm includes a body portion having a first end and a second end and a longitudinal axis defined therebetween, the second end being moveable between a closed position and an open position, the body portion having opposing body lateral sides, each body lateral side extending between the first end and the second end, the body portion having a body portion width defined between the opposing body lateral sides. The at least one arm further includes first and second nondeformable wing extensions, each wing extension extending laterally from a respective lateral side, each wing extension having a lateral outer edge, wherein a maximum arm width is defined between the outer lateral edge of the first wing extension and the outer lateral edge of the second wing extension. The fixation device further includes at least one gripping element moveable relative to the at least one arm to capture a native leaflet therebetween.

3. 发明授权

US11707228B2 Systems and methods for intra-procedural cardiac pressure monitoring 有权
公开(公告)号：US11707228B2
公开(公告)日：2023-07-25
申请号：US17033235
申请日：2020-09-25
申请人： EVALVE, INC.
发明人： Lauren Troxler , Chad Abunassar , Jhey Samson , Eymard Burlaza , Manish Gada
IPC分类号： A61B5/0215 , A61B5/00 , A61M25/00 , A61M25/06
CPC分类号： A61B5/6852 , A61B5/0215 , A61B5/6869 , A61B5/6884 , A61B2560/066 , A61M25/005 , A61M25/0026 , A61M2025/0002 , A61M2025/0003 , A61M2025/0681
摘要： Delivery system for fixation device, including guide catheter with proximal end portion having proximal end port, distal end portion having distal end port, and inner surface defining inner lumen extending in fluid communication between proximal end port and distal end port. Delivery catheter extending through the inner lumen to define annular space between outer surface of the delivery catheter and inner surface of the guide catheter. A pressure sensor proximate the proximal end portion in fluid communication with the annual space to monitor fluid pressure. The distal end portion of the guide catheter includes flow passages in fluid communication between an exterior of the distal end portion and the annular space.

4. 发明申请

US20210093256A1 SYSTEMS AND METHODS FOR INTRA-PROCEDURAL CARDIAC PRESSURE MONITORING 有权
公开(公告)号：US20210093256A1
公开(公告)日：2021-04-01
申请号：US17033235
申请日：2020-09-25
申请人： EVALVE, INC.
发明人： Lauren Troxler , Chad Abunassar , Jhey Samson , Eymard Burlaza , Manish Gada
IPC分类号： A61B5/00 , A61B5/0215
摘要： Delivery system for fixation device, including guide catheter with proximal end portion having proximal end port, distal end portion having distal end port, and inner surface defining inner lumen extending in fluid communication between proximal end port and distal end port. Delivery catheter extending through the inner lumen to define annular space between outer surface of the delivery catheter and inner surface of the guide catheter. A pressure sensor proximate the proximal end portion in fluid communication with the annual space to monitor fluid pressure. The distal end portion of the guide catheter includes flow passages in fluid communication between an exterior of the distal end portion and the annular space.

5. 发明授权

US12048624B2 Independent proximal element actuation methods 有权
公开(公告)号：US12048624B2
公开(公告)日：2024-07-30
申请号：US16930241
申请日：2020-07-15
申请人： EVALVE, INC.
发明人： Koji Kizuka , Richard Childs , Gabriel Gonzales , Dylan Van Hoven , Chad Abunassar , Travis Marsot , Rob Mosley , Nisu Patel , Francisco Valencia
IPC分类号： A61F2/24
CPC分类号： A61F2/2439 , A61F2/2418 , A61F2210/0014 , A61F2220/0016 , A61F2250/0098
摘要： Fixation system for fixation of leaflets of a heart valve including an implantable fixation device having a first arm and a second arm, a first proximal element moveable relative to the first arm between a first position and a second position, and a second proximal element moveable relative to the second arm between a first position and a second position. The fixation system includes a delivery device having a catheter, a first proximal element line and a second proximal element line, and a handle having a first and second proximal element line handles coupled to the first proximal element line and the second proximal element line, respectively. The handle can include an interlock moveable between an unlocked position and a locked position.

6. 发明授权

US11660189B2 Wide clip with nondeformable wings 有权
公开(公告)号：US11660189B2
公开(公告)日：2023-05-30
申请号：US16928599
申请日：2020-07-14
申请人： EVALVE, INC.
发明人： Chad Abunassar , Jessie Garcia , Gabriel Gonzales , Samir Jain , Casey Barbarino , Santosh Prabhu
IPC分类号： A61F2/24
CPC分类号： A61F2/246 , A61F2220/0008 , A61F2230/0093 , A61F2250/0036 , A61F2250/0037
摘要： Fixation device for fixation of leaflets of a heart valve includes a central assembly and at least one arm moveably coupled to the central assembly. The at least one arm includes a body portion having a first end and a second end and a longitudinal axis defined therebetween, the second end being moveable between a closed position and an open position, the body portion having opposing body lateral sides, each body lateral side extending between the first end and the second end, the body portion having a body portion width defined between the opposing body lateral sides. The at least one arm further includes first and second nondeformable wing extensions, each wing extension extending laterally from a respective lateral side, each wing extension having a lateral outer edge, wherein a maximum arm width is defined between the outer lateral edge of the first wing extension and the outer lateral edge of the second wing extension. The fixation device further includes at least one gripping element moveable relative to the at least one arm to capture a native leaflet therebetween.

7. 发明申请

US20210338428A1 LONG ARM VALVE REPAIR CLIP 有权
公开(公告)号：US20210338428A1
公开(公告)日：2021-11-04
申请号：US17374161
申请日：2021-07-13
申请人： EVALVE, INC.
发明人： Chad Abunassar , Jessie Garcia , Tamer Mahmoud , Brandon Chu , Santosh Prabhu
IPC分类号： A61F2/24 , A61B17/29 , A61B17/00 , A61B17/08
摘要： Fixation device for engaging tissue including a pair of fixation elements, each fixation element has a first end and a second end opposite the first end, the first ends are moveable between a closed position and an open position. The fixation device further includes a pair of gripping elements. Each gripping element is moveable with a respective fixation element and disposed in opposition to at least a portion of the respective fixation element to capture tissue therebetween. The fixation device further includes a central portion operatively connected to each gripping element at a respective central portion-gripping element interface. The central portion has at least one distal end and a width “W1” proximate the distal end. Each of the gripping elements has a free end opposite its respective central portion-gripping element interface and a length “L1” defined between the respective central portion-gripping element interface and the free end. The length L1 fixation elements is at least about three times the width W1.

8. 发明授权

US11065119B2 Long arm valve repair clip 有权
公开(公告)号：US11065119B2
公开(公告)日：2021-07-20
申请号：US15977995
申请日：2018-05-11
申请人： EVALVE, INC.
发明人： Chad Abunassar , Jessie Garcia , Tamer Mahmoud , Brandon Chu , Santosh Prabhu
IPC分类号： A61F2/24 , A61B17/29 , A61B17/00 , A61B17/08 , A61B17/04 , A61B17/128
摘要： Fixation device for engaging tissue including a pair of fixation elements, each fixation element has a first end and a second end opposite the first end, the first ends are moveable between a closed position and an open position. The fixation device further includes a pair of gripping elements. Each gripping element is moveable with a respective fixation element and disposed in opposition to at least a portion of the respective fixation element to capture tissue therebetween. The fixation device further includes a central portion operatively connected to each gripping element at a respective central portion-gripping element interface. The central portion has at least one distal end and a width “W1” proximate the distal end. Each of the gripping elements has a free end opposite its respective central portion-gripping element interface and a length “L1” defined between the respective central portion-gripping element interface and the free end. The length L1 fixation elements is at least about three times the width W1.

9. 发明申请

US20210186698A1 WIDE CLIP WITH DEFORMABLE WIDTH 有权
公开(公告)号：US20210186698A1
公开(公告)日：2021-06-24
申请号：US17124259
申请日：2020-12-16
申请人： EVALVE, INC.
发明人： Chad Abunassar , Santosh Prabhu , Casey Barbarino , Jessie Garcia , Gabriel Gonzales , Brandon Chu , Tamer M. Mahmoud , Michael Wei
IPC分类号： A61F2/24
摘要： Fixation device for fixation of leaflets of a heart valve includes a central assembly and at least one arm moveably coupled relative to the central assembly. The at least one arm includes a deformable frame having a first end and a second end and a longitudinal axis defined therebetween, the second end being moveable between a closed position and an open position. The deformable frame further includes first and second deformable flex portions, each flex portion extending along a respective lateral side of the deformable frame and having a deformed condition and an undeformed condition, and each flex portion having an outer lateral edge. The at least one arm has a maximum deformed arm lateral cross-dimension with the flex portions in the deformed condition.

10. 发明授权

US12138169B2 Fixation device having a flexure portion 有权
公开(公告)号：US12138169B2
公开(公告)日：2024-11-12
申请号：US17732830
申请日：2022-04-29
申请人： EVALVE, INC.
发明人： Chad Abunassar , Gabriel Gonzales , Samir Jain , Jill McCoy
IPC分类号： A61F2/24
CPC分类号： A61F2/2466 , A61F2220/0016 , A61F2230/0026
摘要： Fixation device for fixation of leaflets of a heart valve, the fixation device including a central element defining a central axis. The fixation device further includes a distal portion including at least one arm coupled to the central element, wherein the at least one arm is moveable to a selected position between a fully open position and a fully closed position. The distal portion further includes at least one leg operatively coupled to the at least one arm and configured to move the at least one arm to the selected position between the fully open position and the fully closed position. The at least one arm includes a contact portion configured to engage native heart valve tissue, the contact portion defining a contact portion axis. The distal portion includes a flexure portion configured to enable the contact portion in the selected position to move within a flex angle range between an undeformed contact portion angle relative to the central axis and a flexed contact portion angle relative to the central axis. The flexed contact portion angle is greater than the undeformed contact portion angle. The flex angle range is about 10 degrees to about 45 degrees. The fixation device further includes at least one gripping element moveable relative to the at least one arm to capture a native leaflet therebetween.

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